CA1029719A - Preparation de l'a-6-deoxy-5-hydroxytetracycline - Google Patents

Preparation de l'a-6-deoxy-5-hydroxytetracycline

Info

Publication number
CA1029719A
CA1029719A CA224,909A CA224909A CA1029719A CA 1029719 A CA1029719 A CA 1029719A CA 224909 A CA224909 A CA 224909A CA 1029719 A CA1029719 A CA 1029719A
Authority
CA
Canada
Prior art keywords
hydroxytetracycline
deoxy
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA224,909A
Other languages
English (en)
Other versions
CA224909S (en
Inventor
Charles J.V. Scanio
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Application granted granted Critical
Publication of CA1029719A publication Critical patent/CA1029719A/fr
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/24—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton
    • C07C237/26—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton of a ring being part of a condensed ring system formed by at least four rings, e.g. tetracycline
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2231/00—Catalytic reactions performed with catalysts classified in B01J31/00
    • B01J2231/60—Reduction reactions, e.g. hydrogenation
    • B01J2231/64—Reductions in general of organic substrates, e.g. hydride reductions or hydrogenations
    • B01J2231/641—Hydrogenation of organic substrates, i.e. H2 or H-transfer hydrogenations, e.g. Fischer-Tropsch processes
    • B01J2231/645—Hydrogenation of organic substrates, i.e. H2 or H-transfer hydrogenations, e.g. Fischer-Tropsch processes of C=C or C-C triple bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/40—Ortho- or ortho- and peri-condensed systems containing four condensed rings
    • C07C2603/42—Ortho- or ortho- and peri-condensed systems containing four condensed rings containing only six-membered rings
    • C07C2603/44—Naphthacenes; Hydrogenated naphthacenes
    • C07C2603/46—1,4,4a,5,5a,6,11,12a- Octahydronaphthacenes, e.g. tetracyclines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Saccharide Compounds (AREA)
CA224,909A 1974-05-28 1975-04-17 Preparation de l'a-6-deoxy-5-hydroxytetracycline Expired CA1029719A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US473791A US3907890A (en) 1974-05-28 1974-05-28 Preparation of alpha-6-deoxy-5-hydroxytetracycline

Publications (1)

Publication Number Publication Date
CA1029719A true CA1029719A (fr) 1978-04-18

Family

ID=23880982

Family Applications (1)

Application Number Title Priority Date Filing Date
CA224,909A Expired CA1029719A (fr) 1974-05-28 1975-04-17 Preparation de l'a-6-deoxy-5-hydroxytetracycline

Country Status (33)

Country Link
US (1) US3907890A (fr)
JP (1) JPS585185B2 (fr)
AR (1) AR204864A1 (fr)
AT (1) AT338421B (fr)
BE (1) BE829344A (fr)
BG (1) BG29427A3 (fr)
CA (1) CA1029719A (fr)
CH (1) CH602592A5 (fr)
CS (1) CS176141B2 (fr)
DE (1) DE2520546A1 (fr)
DK (1) DK145877C (fr)
EG (1) EG11666A (fr)
ES (1) ES437047A1 (fr)
FI (1) FI58910C (fr)
FR (1) FR2272978B1 (fr)
GB (1) GB1478587A (fr)
HK (1) HK28579A (fr)
HU (1) HU169913B (fr)
IE (1) IE41554B1 (fr)
IL (1) IL47118A (fr)
IN (1) IN141263B (fr)
KE (1) KE2935A (fr)
LU (1) LU72566A1 (fr)
MY (1) MY7900244A (fr)
NL (1) NL180310C (fr)
NO (1) NO146199C (fr)
PH (1) PH10678A (fr)
PL (1) PL96623B1 (fr)
RO (1) RO72528A (fr)
SE (1) SE421612B (fr)
SU (1) SU578865A3 (fr)
YU (1) YU39319B (fr)
ZA (1) ZA752639B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3962131A (en) * 1975-01-28 1976-06-08 Pfizer Inc. Rhodium containing catalyst and use thereof in preparation of 6-deoxy-5-oxytetracycline
US4218340A (en) * 1975-11-19 1980-08-19 Eastman Kodak Company Nickel and cobalt containing carbonylation catalyst compositions for the production of carboxylic acids and their esters
US4374752A (en) * 1981-06-30 1983-02-22 Union Carbide Corporation Catalyst and process for the conversion of methanol to acetaldehyde
US4500458A (en) * 1982-01-19 1985-02-19 Plurichemie Anstalt Process for the preparation of α-6-deoxytetracyclines
DK386784A (da) * 1983-08-17 1985-02-18 Hovione Int Ltd Fremgangsmaade til fremstilling af alfa-6-desoxy-tetracykliner
JPS6220097A (ja) * 1985-07-19 1987-01-28 能美防災株式会社 蓄積型火災受信機
JPS6425298A (en) * 1987-07-21 1989-01-27 Yazaki Corp Gas leakage warning device
US4973719A (en) * 1988-10-28 1990-11-27 Ranbaxy Laboratories Limited Process for the production of alpha-6-deoxytetracyclines
EP0391005B1 (fr) * 1989-04-03 1991-10-16 Ranbaxy Laboratories, Ltd. Procédé de préparation d'alpha-6-déoxytétracyclines
US4902447A (en) * 1988-10-28 1990-02-20 Ranbaxy Laboratories Limited Process for the production of alpha-6-deoxytetracyclines and hydrogenation catalyst useful therein
US4987242A (en) * 1988-10-28 1991-01-22 Jagmohan Khanna Hydrogenation catalyst useful in the production of alpha-6-deoxytetracyclines
US5049683A (en) * 1989-01-04 1991-09-17 Houba, Inc. Process for the production of alpha-6-deoxytetracyclines

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1430859A (fr) * 1960-05-23 1966-05-25
GB1182353A (en) * 1966-02-07 1970-02-25 Montedison Spa Cobalt Hydrocarbonyls
US3444198A (en) * 1967-02-13 1969-05-13 Pfizer & Co C Process for producing alpha-6-deoxytetracyclines
US3692864A (en) * 1970-09-30 1972-09-19 Texaco Inc Hydrogenation process utilizing homogeneous metal catalysts
US3717585A (en) * 1971-01-08 1973-02-20 Phillips Petroleum Co Promoted trihydrocarbylphosphine modified carbonyl cobalt catalyst system

Also Published As

Publication number Publication date
LU72566A1 (fr) 1976-03-17
BG29427A3 (en) 1980-11-14
YU39319B (en) 1984-10-31
HU169913B (fr) 1977-02-28
IL47118A0 (en) 1975-06-25
ES437047A1 (es) 1977-01-16
GB1478587A (en) 1977-07-06
FR2272978B1 (fr) 1978-06-09
CH602592A5 (fr) 1978-07-31
FI751437A (fr) 1975-11-29
KE2935A (en) 1979-03-30
DK145877C (da) 1983-09-12
NL180310C (nl) 1987-02-02
FI58910C (fi) 1981-05-11
CS176141B2 (fr) 1977-06-30
US3907890A (en) 1975-09-23
ZA752639B (en) 1976-04-28
DK225075A (da) 1975-11-29
ATA359375A (de) 1976-12-15
NO751389L (fr) 1975-12-01
BE829344A (fr) 1975-11-24
IE41554B1 (en) 1980-01-30
NO146199C (no) 1982-08-18
FR2272978A1 (fr) 1975-12-26
NL7505943A (nl) 1975-12-02
SE7504140L (sv) 1975-12-01
FI58910B (fi) 1981-01-30
EG11666A (en) 1978-03-29
PH10678A (en) 1977-08-05
DE2520546A1 (de) 1975-12-04
AT338421B (de) 1977-08-25
NO146199B (no) 1982-05-10
IL47118A (en) 1978-01-31
NL180310B (nl) 1986-09-01
IN141263B (fr) 1977-02-05
DK145877B (da) 1983-03-28
IE41554L (en) 1975-11-28
AR204864A1 (es) 1976-03-05
PL96623B1 (pl) 1978-01-31
SU578865A3 (ru) 1977-10-30
YU132875A (en) 1982-05-31
JPS50160261A (fr) 1975-12-25
RO72528A (fr) 1981-11-04
HK28579A (en) 1979-05-11
JPS585185B2 (ja) 1983-01-29
MY7900244A (en) 1979-12-31
SE421612B (sv) 1982-01-18

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