CA1020938A - Process for the preparation of 7-alkylthio substituted lincomycins - Google Patents

Process for the preparation of 7-alkylthio substituted lincomycins

Info

Publication number
CA1020938A
CA1020938A CA191,996A CA191996A CA1020938A CA 1020938 A CA1020938 A CA 1020938A CA 191996 A CA191996 A CA 191996A CA 1020938 A CA1020938 A CA 1020938A
Authority
CA
Canada
Prior art keywords
lincomycins
preparation
alkylthio substituted
alkylthio
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA191,996A
Other languages
English (en)
French (fr)
Other versions
CA191996S (en
Inventor
Brian Bannister
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Priority to CA285,191A priority Critical patent/CA1034946A/en
Priority to CA285,192A priority patent/CA1034947A/en
Application granted granted Critical
Publication of CA1020938A publication Critical patent/CA1020938A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/14—Acyclic radicals, not substituted by cyclic structures attached to a sulfur, selenium or tellurium atom of a saccharide radical
    • C07H15/16—Lincomycin; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
    • C07D327/04—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
    • C07D327/06—Six-membered rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
CA191,996A 1973-03-06 1974-02-07 Process for the preparation of 7-alkylthio substituted lincomycins Expired CA1020938A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CA285,191A CA1034946A (en) 1973-03-06 1977-08-22 PREPARATION OF ALKYLTHIO-.alpha.-THIOLINCOSAMINIDES
CA285,192A CA1034947A (en) 1973-03-06 1977-08-22 PREPARATION OF ALKYLTHIO-.alpha.-THIOLINCOSAMINIDES

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US338459A US3870699A (en) 1973-03-06 1973-03-06 Lincomycin analogs

Publications (1)

Publication Number Publication Date
CA1020938A true CA1020938A (en) 1977-11-15

Family

ID=23324898

Family Applications (1)

Application Number Title Priority Date Filing Date
CA191,996A Expired CA1020938A (en) 1973-03-06 1974-02-07 Process for the preparation of 7-alkylthio substituted lincomycins

Country Status (15)

Country Link
US (2) US3870699A (ko)
JP (1) JPS5857439B2 (ko)
BE (1) BE811931A (ko)
CA (1) CA1020938A (ko)
CH (1) CH617440A5 (ko)
CS (1) CS195677B2 (ko)
FR (1) FR2220252B1 (ko)
GB (1) GB1447462A (ko)
HU (2) HU170910B (ko)
NL (1) NL7402239A (ko)
PL (4) PL101373B1 (ko)
SE (2) SE420098B (ko)
SU (1) SU944506A3 (ko)
YU (1) YU36744B (ko)
ZA (1) ZA74935B (ko)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01280176A (ja) * 1988-04-30 1989-11-10 Sekisui Plastics Co Ltd コンクリート構造物の孔あけ方法
US20030073826A1 (en) * 2001-08-28 2003-04-17 Chao Robert S. Crystaline clindamycin free base
US7199105B2 (en) * 2002-08-15 2007-04-03 Vicuron Pharmaceuticals, Inc. Lincomycin derivatives possessing antibacterial activity
MXPA05001689A (es) * 2002-08-15 2005-05-27 Vicuron Pharm Inc Derivados de lincomicina que poseen actividad antibacteriana.
US7199106B2 (en) 2003-06-17 2007-04-03 Vicuron Pharmaceuticals, Inc. Lincomycin derivatives possessing antimicrobial activity
US7256177B2 (en) 2003-06-17 2007-08-14 Vicuron Pharmaceuticals, Inc. Lincomycin derivatives possessing antibacterial activity
US7361743B2 (en) * 2004-02-11 2008-04-22 Pfizer Inc Lincomycin derivatives possessing antibacterial activity
EP1970377A4 (en) 2005-12-09 2013-02-27 Meiji Seika Kaisha LINCOMYCIN DERIVATIVE AND ANTIBACTERIAL AGENT CONTAINING THIS AS AN ACTIVE SUBSTANCE
TWI499414B (zh) * 2006-09-29 2015-09-11 Lexicon Pharmaceuticals Inc 鈉與葡萄糖第２型共同運輸體（ｃｏ-ｔｒａｎｓｐｏｒｔｅｒ ２）的抑制物與其應用方法
US7879808B2 (en) * 2007-05-31 2011-02-01 Meiji Seika Kaisha, Ltd. Lincomycin derivatives and antimicrobial agents comprising the same as active ingredient
US7867980B2 (en) * 2007-05-31 2011-01-11 Meiji Seika Kaisha, Ltd. Lincosamide derivatives and antimicrobial agents comprising the same as active ingredient
TWI472521B (zh) * 2008-07-17 2015-02-11 Lexicon Pharmaceuticals Inc （２ｓ，３ｒ，４ｒ，５ｓ，６ｒ）－２－（４－氯－３－（４－乙氧苄基）苯基）－６－（甲硫）四氫－２ｈ－哌喃－３，４，５－三醇的固體形態與其使用方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3271385A (en) * 1964-04-13 1966-09-06 Upjohn Co Carbamoyl derivatives of lincomycin and processes for producing them
US3702322A (en) * 1970-04-06 1972-11-07 Upjohn Co Derivatives of lincomycin and its analogs and process
US3689474A (en) * 1970-08-04 1972-09-05 Upjohn Co 7-mercapto-7-deoxylincomycins and process for preparing the same

Also Published As

Publication number Publication date
SE435625B (sv) 1984-10-08
USRE29558E (en) 1978-02-28
PL102862B1 (pl) 1979-04-30
FR2220252B1 (ko) 1977-11-10
SE420098B (sv) 1981-09-14
AU6569774A (en) 1975-08-21
NL7402239A (ko) 1974-09-10
JPS5857439B2 (ja) 1983-12-20
BE811931A (fr) 1974-09-06
CS195677B2 (en) 1980-02-29
SE7712151L (sv) 1977-10-27
PL102863B1 (pl) 1979-04-30
YU36744B (en) 1984-08-31
ZA74935B (en) 1974-12-24
PL101373B1 (pl) 1978-12-30
HU170525B (ko) 1977-06-28
US3870699A (en) 1975-03-11
GB1447462A (en) 1976-08-25
CH617440A5 (ko) 1980-05-30
YU58274A (en) 1982-02-25
SU944506A3 (ru) 1982-07-15
PL102355B1 (pl) 1979-03-31
JPS49134617A (ko) 1974-12-25
HU170910B (hu) 1977-09-28
FR2220252A1 (ko) 1974-10-04

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