CA1003833A - Pyridazine derivatives - Google Patents

Pyridazine derivatives

Info

Publication number
CA1003833A
CA1003833A CA144,468A CA144468A CA1003833A CA 1003833 A CA1003833 A CA 1003833A CA 144468 A CA144468 A CA 144468A CA 1003833 A CA1003833 A CA 1003833A
Authority
CA
Canada
Prior art keywords
pyridazine derivatives
pyridazine
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA144,468A
Other languages
English (en)
Other versions
CA144468S (fr
Inventor
Henri Laborit
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of CA1003833A publication Critical patent/CA1003833A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/20—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA144,468A 1971-06-18 1972-06-12 Pyridazine derivatives Expired CA1003833A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB2873771 1971-06-18
FR7219096A FR2141697B1 (da) 1971-06-18 1972-05-29

Publications (1)

Publication Number Publication Date
CA1003833A true CA1003833A (en) 1977-01-18

Family

ID=26217112

Family Applications (1)

Application Number Title Priority Date Filing Date
CA144,468A Expired CA1003833A (en) 1971-06-18 1972-06-12 Pyridazine derivatives

Country Status (13)

Country Link
US (1) US4169158A (da)
JP (1) JPS5550943B1 (da)
AR (1) AR192370A1 (da)
AU (1) AU472247B2 (da)
BE (1) BE784727A (da)
CA (1) CA1003833A (da)
CH (1) CH546769A (da)
DE (1) DE2229215C2 (da)
ES (1) ES403998A1 (da)
FR (1) FR2141697B1 (da)
GB (1) GB1345880A (da)
NL (1) NL177893C (da)
SE (1) SE392899B (da)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2510998B1 (fr) * 1981-08-07 1986-01-10 Sanofi Sa Nouveaux derives amines de la pyridazine, leur procede de preparation et les medicaments, a action desinhibitrice, qui en comportent
FR2510997A1 (fr) * 1981-08-10 1983-02-11 Sanofi Sa Nouveaux derives de la methyl-4 phenyl-6 pyridazine, procede pour leur preparation et medicaments actifs sur le systeme nerveux central en contenant
FR2511366A1 (fr) * 1981-08-11 1983-02-18 Sanofi Sa Nouveaux derives de la pyridazine, leur procede de preparation et les medicaments, actifs sur le systeme nerveux central, qui en contiennent
FR2539741A1 (fr) * 1983-01-21 1984-07-27 Sanofi Sa Composes a noyau heterocyclique diazote, leur procede de preparation et les medicaments, actifs sur le systeme nerveux central, qui en contiennent
FR2539742B1 (fr) * 1983-01-24 1986-09-05 Sanofi Sa Derives amines de la pyridazine substitues en position 6 par un heterocycle ou un alicycle, lesdits derives etant actifs sur le systeme nerveux central
FR2539739B1 (fr) * 1983-01-24 1985-11-22 Sanofi Sa Nouveaux derives de la naphtyl pyridazine actifs sur le systeme nerveux central, procede de preparation de ces derives et medicaments en contenant
CA1218655A (en) * 1983-01-28 1987-03-03 Kathleen Biziere Process for the preparation of pyridazine derivatives having a psychotropic action
FR2540115B1 (fr) * 1983-01-28 1985-06-07 Sanofi Sa Derive de la pyridazine ayant une action psychotrope, son mode de preparation et les medicaments en contenant
FR2555178B1 (fr) * 1983-11-18 1986-04-18 Sanofi Sa Derives cyanes de la pyridazine ayant une action psychotrope, leur mode de preparation et les medicaments en contenant
FR2625201B1 (fr) * 1987-12-24 1990-06-15 Sanofi Sa Nouveaux derives tricycliques agonistes des recepteurs cholinergiques et medicaments en contenant
FR2642648B1 (fr) * 1989-02-07 1991-06-21 Sanofi Sa Utilisation de derives d'alkyl-5 pyridazine comme medicaments actifs sur le systeme cholinergique
FR2642757B1 (fr) * 1989-02-07 1991-05-24 Sanofi Sa Nouveaux derives de la pyridazine, procede de preparation et compositions pharmaceutiques en contenant
US5461053A (en) * 1989-02-07 1995-10-24 Sanofi Pyridazine derivatives
FR2642754B1 (fr) * 1989-02-07 1991-05-24 Sanofi Sa Nouveaux derives de la pyridazine, procede de preparation et compositions pharmaceutiques en contenant
PT93060B (pt) 1989-02-07 1995-12-29 Sanofi Sa Processo para a obtencao de derivados de piridazina e de composicoes farmaceuticas que os contem
US20100210590A1 (en) * 1995-09-27 2010-08-19 Northwestern University Compositions and treatments for seizure-related disorders
US20030176437A1 (en) 2001-08-31 2003-09-18 D.M. Watterson Anti-inflammatory and protein kinase inhibitor compositions and related methods for downregulation of detrimental cellular responses and inhibition of cell death
BRPI0517947A (pt) 2004-11-02 2008-10-21 Univ Northwestern composto de piridazina, composições e métodos
WO2006050359A2 (en) 2004-11-02 2006-05-11 Northwestern University Pyridazine compounds and methods
RU2442775C2 (ru) * 2005-07-04 2012-02-20 Хай Пойнт Фармасьютикалс, ЛЛС Антагонисты гистаминовых н3-рецепторов
AU2006264966B2 (en) * 2005-07-04 2013-02-21 High Point Pharmaceuticals, Llc Histamine H3 receptor antagonists
AU2007243280A1 (en) 2006-04-28 2007-11-08 Northwestern University Formulations containing pyridazine compounds for treating neuroinflammatory diseases
CA2650704A1 (en) * 2006-04-28 2007-11-08 Northwestern University Salts of pyridazine compounds
EP2015750A2 (en) 2006-04-28 2009-01-21 Northwestern University Compositions and treatments using pyridazine compounds and cholinesterase inhibitors
EP2038256A1 (en) 2006-05-23 2009-03-25 TransTech Pharma, Inc 6- (4-cyclopropylpiperazin-1-yl) -2 ' -methyl- [3, 4 ']-bipyridine and its use as a medicament
CA2659570C (en) 2006-05-29 2015-10-06 High Point Pharmaceuticals, Llc 3-(1,3-benzodioxol-5-yl)-6-(4-cyclopropylpiperazin-1-yl)-pyridazine, its salts and solvates and its use as histamine h3 receptor antagonist
EP2014656A3 (en) 2007-06-11 2011-08-24 High Point Pharmaceuticals, LLC New heteocyclic h3 antagonists
US8461389B2 (en) 2008-04-18 2013-06-11 University College Dublin, National University Of Ireland, Dublin Psycho-pharmaceuticals
US9133123B2 (en) 2010-04-23 2015-09-15 Cytokinetics, Inc. Certain amino-pyridines and amino-triazines, compositions thereof, and methods for their use
AR081626A1 (es) * 2010-04-23 2012-10-10 Cytokinetics Inc Compuestos amino-piridazinicos, composiciones farmaceuticas que los contienen y uso de los mismos para tratar trastornos musculares cardiacos y esqueleticos
AR081331A1 (es) 2010-04-23 2012-08-08 Cytokinetics Inc Amino- pirimidinas composiciones de las mismas y metodos para el uso de los mismos
KR20200124661A (ko) 2018-01-23 2020-11-03 인스티튜트 구스타브 루시 종양 성장을 감소시키기 위한 미나프린의 용도

Also Published As

Publication number Publication date
AU4350072A (en) 1973-12-20
BE784727A (fr) 1972-10-02
JPS5550943B1 (da) 1980-12-20
US4169158A (en) 1979-09-25
AR192370A1 (es) 1973-02-14
FR2141697B1 (da) 1976-09-17
ES403998A1 (es) 1975-06-01
SE392899B (sv) 1977-04-25
DE2229215C2 (de) 1984-09-06
CH546769A (fr) 1974-03-15
NL177893B (nl) 1985-07-16
GB1345880A (en) 1974-02-06
NL7208355A (da) 1972-12-20
FR2141697A1 (da) 1973-01-26
NL177893C (nl) 1985-12-16
AU472247B2 (en) 1973-12-20
DE2229215A1 (de) 1973-01-25

Similar Documents

Publication Publication Date Title
CA1003833A (en) Pyridazine derivatives
AU468250B2 (en) 3-nitropyrazole derivatives
CA943542A (en) Aminopyridazine derivatives
AU462723B2 (en) 2-nitro-5-imidazolyaldehyde derivatives
AU461957B2 (en) Lumilysergol derivatives
CA1017335A (en) Triazolyl-ethenyl-phenylene derivatives
AU463679B2 (en) Dibenzocycloheptadioxolan derivatives
AU470552B2 (en) Aminocephalosporin derivatives
AU472069B2 (en) Dibenzoxirenazepine derivatives
CA867769A (en) Fluoracylamino-trichloromethyl-methane derivatives
CA868361A (en) Thieno-benzothiazine derivatives
CA862754A (en) Benzothiazepin-4-one derivatives
CA871723A (en) Pyridyl-2-imidazolone derivatives
CA871716A (en) Norscopolamine derivatives
CA869544A (en) Thieno-benzothiazine derivatives
CA872254A (en) Indenopyridine derivatives
CA873890A (en) 5-nitrofuran derivatives
CA866804A (en) Spiro-azatetramethylene derivatives
CA863950A (en) Thienobenzothiazephine derivatives
CA863356A (en) Indenopyridine derivatives
CA862773A (en) N-phenylsuccinimide derivatives
AU463550B2 (en) Nitrofurylpyrimidine derivatives
CA874996A (en) Diaryloxalamide derivatives
AU479054B2 (en) Triazole-ethenyl-phenylene derivatives
CA879103A (en) 3-amino-propoxy-indole derivatives