BRPI1012219C1 - produto, substrato, composição farmacêutica, usos de um produto, e de um peptídeo antimicrobiano, métodos para prevenir formação de biofilme em um ambiente, para tratar uma infecção microbiana por profilaxia ou terapia, e para tratar ou prevenir formação de biofilme em um ambiente, e, uso de uma cisteamina - Google Patents
produto, substrato, composição farmacêutica, usos de um produto, e de um peptídeo antimicrobiano, métodos para prevenir formação de biofilme em um ambiente, para tratar uma infecção microbiana por profilaxia ou terapia, e para tratar ou prevenir formação de biofilme em um ambiente, e, uso de uma cisteaminaInfo
- Publication number
- BRPI1012219C1 BRPI1012219C1 BRPI1012219A BRPI1012219A BRPI1012219C1 BR PI1012219 C1 BRPI1012219 C1 BR PI1012219C1 BR PI1012219 A BRPI1012219 A BR PI1012219A BR PI1012219 A BRPI1012219 A BR PI1012219A BR PI1012219 C1 BRPI1012219 C1 BR PI1012219C1
- Authority
- BR
- Brazil
- Prior art keywords
- product
- treat
- environment
- biofilm formation
- prevent biofilm
- Prior art date
Links
- 108700042778 Antimicrobial Peptides Proteins 0.000 title abstract 3
- 102000044503 Antimicrobial Peptides Human genes 0.000 title abstract 3
- 230000032770 biofilm formation Effects 0.000 title abstract 3
- 239000003910 polypeptide antibiotic agent Substances 0.000 title abstract 3
- UFULAYFCSOUIOV-UHFFFAOYSA-N cysteamine Chemical compound NCCS UFULAYFCSOUIOV-UHFFFAOYSA-N 0.000 title abstract 2
- 208000015181 infectious disease Diseases 0.000 title abstract 2
- 229960003151 mercaptamine Drugs 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 230000000813 microbial effect Effects 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 239000000047 product Substances 0.000 title abstract 2
- 239000000758 substrate Substances 0.000 title abstract 2
- 238000011321 prophylaxis Methods 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 title 1
- 230000003214 anti-biofilm Effects 0.000 abstract 3
- 239000003795 chemical substances by application Substances 0.000 abstract 3
- 239000000853 adhesive Substances 0.000 abstract 1
- 230000000181 anti-adherent effect Effects 0.000 abstract 1
- 239000002270 dispersing agent Substances 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
- A01N33/02—Amines; Quaternary ammonium compounds
- A01N33/08—Amines; Quaternary ammonium compounds containing oxygen or sulfur
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/145—Amines having sulfur, e.g. thiurams (>N—C(S)—S—C(S)—N< and >N—C(S)—S—S—C(S)—N<), Sulfinylamines (—N=SO), Sulfonylamines (—N=SO2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- A61K38/1729—Cationic antimicrobial peptides, e.g. defensins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/44—Medicaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/46—Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
- A61L29/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
- A61L2300/254—Enzymes, proenzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/424—Anti-adhesion agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/45—Mixtures of two or more drugs, e.g. synergistic mixtures
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Materials Engineering (AREA)
- Hematology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Zoology (AREA)
- Surgery (AREA)
- Marine Sciences & Fisheries (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Dermatology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Wood Science & Technology (AREA)
- Environmental Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Dentistry (AREA)
- Plant Pathology (AREA)
- Pest Control & Pesticides (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16539609P | 2009-03-31 | 2009-03-31 | |
| GBGB0905451.1A GB0905451D0 (en) | 2009-03-31 | 2009-03-31 | Biofilms |
| PCT/GB2010/000631 WO2010112848A2 (en) | 2009-03-31 | 2010-03-31 | Inhibition of biofilm organisms |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BRPI1012219A2 BRPI1012219A2 (pt) | 2016-03-29 |
| BRPI1012219B8 BRPI1012219B8 (pt) | 2020-05-12 |
| BRPI1012219C1 true BRPI1012219C1 (pt) | 2021-05-25 |
Family
ID=40671951
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI1012219A BRPI1012219C1 (pt) | 2009-03-31 | 2010-03-31 | produto, substrato, composição farmacêutica, usos de um produto, e de um peptídeo antimicrobiano, métodos para prevenir formação de biofilme em um ambiente, para tratar uma infecção microbiana por profilaxia ou terapia, e para tratar ou prevenir formação de biofilme em um ambiente, e, uso de uma cisteamina |
Country Status (21)
| Country | Link |
|---|---|
| US (3) | US9339525B2 (enExample) |
| EP (1) | EP2413949B1 (enExample) |
| JP (1) | JP5727994B2 (enExample) |
| KR (1) | KR101852784B1 (enExample) |
| CN (2) | CN104257645A (enExample) |
| AU (2) | AU2010231136B2 (enExample) |
| BR (1) | BRPI1012219C1 (enExample) |
| CA (1) | CA2755878C (enExample) |
| CY (1) | CY1121175T1 (enExample) |
| GB (1) | GB0905451D0 (enExample) |
| IL (1) | IL215369B2 (enExample) |
| MX (1) | MX358018B (enExample) |
| NZ (1) | NZ595037A (enExample) |
| PL (1) | PL2413949T3 (enExample) |
| RU (1) | RU2548786C2 (enExample) |
| SG (2) | SG10201400926VA (enExample) |
| SI (1) | SI2413949T1 (enExample) |
| TR (1) | TR201821161T4 (enExample) |
| UA (1) | UA106743C2 (enExample) |
| WO (1) | WO2010112848A2 (enExample) |
| ZA (1) | ZA201107140B (enExample) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008143889A1 (en) | 2007-05-14 | 2008-11-27 | Research Foundation Of State University Of New York | Induction of a physiological dispersion response in bacterial cells in a biofilm |
| GB0905451D0 (en) * | 2009-03-31 | 2009-05-13 | Novabiotics Ltd | Biofilms |
| TWI403330B (zh) * | 2010-03-29 | 2013-08-01 | Rise technology co ltd | 低血球溶解性之抗微生物胜肽、醫藥組成物及其用途 |
| GB201016733D0 (en) * | 2010-10-05 | 2010-11-17 | Novabiotics Ltd | Compounds and their use |
| BR112012026880B1 (pt) * | 2010-04-27 | 2021-03-16 | Lysando Ag | método para eliminação ou redução de um biofilme bacteriano, variante de endolisina ou variante de bacteriocina e seus usos |
| GB201021186D0 (en) * | 2010-12-14 | 2011-01-26 | Novabiotics Ltd | Composition |
| RU2013150536A (ru) | 2011-05-12 | 2015-06-20 | Смит & Невью Ортопедикс АГ | Способ и топическая композиция для обработки ран, содержащая seaprose и его применение |
| TWI415572B (zh) | 2011-06-17 | 2013-11-21 | Univ Chang Gung | 利用１，２，３，４，６－五－ｏ－沒食子醯基－ｄ－葡哌喃糖來抑制生物膜形成 |
| US20140315789A1 (en) * | 2011-11-23 | 2014-10-23 | Newsouth Innovations Pty Limited | Antimicrobial peptides and uses thereof |
| ES2991989T3 (es) | 2012-03-23 | 2024-12-05 | Macro Biologics Inc | Composiciones y usos de materiales antimicrobianos con propiedades compatibles con tejidos |
| RU2014145270A (ru) * | 2012-05-11 | 2016-07-10 | Смит & Невью, Инк. | Способ и композиция для разрушения бактериальной биопленки |
| WO2014016979A1 (ja) * | 2012-07-27 | 2014-01-30 | 住友重機械工業株式会社 | 微生物活性調節剤及び微生物の活性を調節する方法 |
| US20160289287A1 (en) * | 2013-08-27 | 2016-10-06 | The University Of British Columbia | Small cationic anti-biofilm and idr peptides |
| GB201405891D0 (en) * | 2014-04-02 | 2014-05-14 | Novabiotics Ltd | Modified antimicrobial peptides |
| US20160102052A1 (en) * | 2014-09-22 | 2016-04-14 | Novabiotics Limited | Use of Cysteamine in Treating Infections caused by Yeasts/Moulds |
| GB201416727D0 (en) * | 2014-09-22 | 2014-11-05 | Novabiotics Ltd | Use |
| GB201510077D0 (en) * | 2015-06-10 | 2015-07-22 | Novabiotics Ltd | Use |
| US11103547B2 (en) | 2016-02-04 | 2021-08-31 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Methods for disrupting biofilms |
| EP3416669B1 (en) * | 2016-02-19 | 2025-05-28 | Klaus Brandenburg | Means and methods for treating bacterial infections |
| WO2017176796A1 (en) | 2016-04-04 | 2017-10-12 | University Of Virginia Patent Foundation | Compositions and methods for preventing and treating disease |
| EP3241570A1 (en) * | 2016-05-02 | 2017-11-08 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Polypeptide and hyaluronic acid coatings |
| JP7249149B2 (ja) * | 2016-05-12 | 2023-03-30 | ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア | バイオフィルムの堆積および産生を阻害するための組成物および方法 |
| WO2017212239A1 (en) * | 2016-06-07 | 2017-12-14 | Novabiotics Limited | Treatment of drug-resistant microbial infections |
| WO2018020435A1 (en) | 2016-07-27 | 2018-02-01 | Smith & Nephew, Inc. | Use of thermolysin to reduce or eliminate bacterial biofilms from surfaces |
| EP3554491B1 (en) | 2016-12-15 | 2023-02-15 | Zambon S.p.A. | N-acetylcysteine for use as antibacterial agent |
| WO2018112511A1 (en) * | 2016-12-22 | 2018-06-28 | Whiteley Corporation Pty Ltd | Biofilm disrupting composition |
| EP3565613A4 (en) * | 2017-01-05 | 2020-07-29 | Cormedix Inc. | ANTIMICROBIAL COMPOSITIONS, INCLUDING ANTIMICROBIAL HYDROGELS, EFFECTIVE AGAINST MATURE BIOFILMS |
| WO2018140707A1 (en) | 2017-01-30 | 2018-08-02 | Smith & Nephew, Inc. | Synergistic combination of thermolysin and an antibacterial agent to reduce eliminate bacterial biofilms from surfaces |
| MX393548B (es) | 2017-04-06 | 2025-03-24 | Amicrobe Inc | Composiciones y usos de polipéptidos catiónicos, sintéticos, antimicrobianos localmente aplicados con seguridad y desempeño mejorados. |
| RU2664708C1 (ru) * | 2017-06-08 | 2018-08-21 | Сергей Иванович Черныш | Способ разрушения и предотвращения образования бактериальных биопленок комплексом антимикробных пептидов насекомых |
| CN108048359B (zh) * | 2017-12-27 | 2020-12-01 | 广州立白企业集团有限公司 | 一种牙菌斑生物膜模型的培养方法和优化的生物膜活菌计数法及应用 |
| EP3765057A4 (en) * | 2018-03-13 | 2022-01-05 | Peptilogics, Inc. | TREATMENT OF IMPLANTS WITH SPECIFICALLY MODIFIED ANTIMICROBIAL AMPHIPHILE PEPTIDES |
| CN108753632A (zh) * | 2018-05-25 | 2018-11-06 | 安徽中医药大学 | 一种溶解白念珠菌生物被膜胞外基质的方法 |
| US11541105B2 (en) | 2018-06-01 | 2023-01-03 | The Research Foundation For The State University Of New York | Compositions and methods for disrupting biofilm formation and maintenance |
| FI3866775T3 (fi) * | 2018-10-17 | 2025-07-10 | Novabiotics Ltd | Kysteamiini käytettäväksi keuhkosairauksien hoidossa |
| CN110402928A (zh) * | 2019-08-08 | 2019-11-05 | 杭州博菲医疗器械有限公司 | 一种抑菌功能液及应用该抑菌功能液的导管组件 |
| CN110583697B (zh) * | 2019-09-20 | 2021-04-06 | 浙江工商大学 | 去除铜绿假单胞菌生物膜用的高效化学生物制剂及其应用 |
| CN111675751B (zh) * | 2020-04-08 | 2022-06-14 | 天津医科大学口腔医院 | 一种抗菌肽及其应用 |
| GB202010268D0 (en) * | 2020-07-03 | 2020-08-19 | Novabiotics Ltd | Nail formulations and treatment regimes |
| US12371463B2 (en) | 2021-04-20 | 2025-07-29 | University of Pittsburgh—of the Commonwealth System of Higher Education | Methods and compositions for treatment of antibiotic-resistant bacterial infections |
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|---|---|---|---|---|
| IT1055560B (it) * | 1974-05-02 | 1982-01-11 | Istituto Chemioterapico | Derivati pirimidinici e relative composizioni per il trattamento di infezioni virali |
| WO2000033895A1 (en) * | 1998-12-07 | 2000-06-15 | Baylor College Of Medicine | Preventing and removing biofilm from the surface of medical devices |
| ITMI20021881A1 (it) * | 2002-09-04 | 2004-03-05 | Zambon Spa | Composizioni farmaceutiche per il trattamento di infezioni da patogeni dell'apparato urinario. |
| GB2398497A (en) * | 2003-02-19 | 2004-08-25 | Walcom Animal Science | Composition for improving immunity of animals |
| EP1778720B1 (en) * | 2004-08-18 | 2010-09-01 | Novabiotics Limited | Antimicrobial peptides comprising an arginine- and/or lysine-containing motif |
| US20070093894A1 (en) * | 2005-10-25 | 2007-04-26 | Baylor College Of Medicine | Incorporation of antimicrobial combinations onto devices to reduce infection |
| AR057623A1 (es) * | 2005-11-28 | 2007-12-05 | Omega Bio Pharma H K Ltd | Materiales y metodos para el tratamiento de las infecciones virales |
| ZA200805191B (en) * | 2005-11-28 | 2009-08-26 | Hk Omega Biopharma Ltd | Materials and methods for treating viral infections with a cysteamine compound |
| GB0702021D0 (en) * | 2007-02-02 | 2007-03-14 | Novabiotics Ltd | Peptides and their use |
| WO2009023356A2 (en) * | 2007-05-25 | 2009-02-19 | Omega-Biopharma (H.K.) Limited | Materials and methods for treating influenza infections |
| CN102006785A (zh) * | 2008-02-17 | 2011-04-06 | 华扩达动物科学(I.P.3)有限公司 | 改善虾健康的材料和方法 |
| GB0905451D0 (en) * | 2009-03-31 | 2009-05-13 | Novabiotics Ltd | Biofilms |
| GB201021186D0 (en) * | 2010-12-14 | 2011-01-26 | Novabiotics Ltd | Composition |
| US20160106689A1 (en) * | 2014-09-22 | 2016-04-21 | Novabiotics Limited | Use |
| US20160102052A1 (en) * | 2014-09-22 | 2016-04-14 | Novabiotics Limited | Use of Cysteamine in Treating Infections caused by Yeasts/Moulds |
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2009
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2010
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