SG10201400926VA - Inhibition of biofilm organisms - Google Patents

Inhibition of biofilm organisms

Info

Publication number
SG10201400926VA
SG10201400926VA SG10201400926VA SG10201400926VA SG10201400926VA SG 10201400926V A SG10201400926V A SG 10201400926VA SG 10201400926V A SG10201400926V A SG 10201400926VA SG 10201400926V A SG10201400926V A SG 10201400926VA SG 10201400926V A SG10201400926V A SG 10201400926VA
Authority
SG
Singapore
Prior art keywords
inhibition
biofilm organisms
biofilm
organisms
Prior art date
Application number
SG10201400926VA
Inventor
Deborah O'neil
Derry Mercer
Cedric Charrier
Original Assignee
Novabiotics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novabiotics Ltd filed Critical Novabiotics Ltd
Publication of SG10201400926VA publication Critical patent/SG10201400926VA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/145Amines having sulfur, e.g. thiurams (>N—C(S)—S—C(S)—N< and >N—C(S)—S—S—C(S)—N<), Sulfinylamines (—N=SO), Sulfonylamines (—N=SO2)
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N33/00Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
    • A01N33/02Amines; Quaternary ammonium compounds
    • A01N33/08Amines; Quaternary ammonium compounds containing oxygen or sulfur
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A61K38/1729Cationic antimicrobial peptides, e.g. defensins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties
    • A61L15/44Medicaments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties
    • A61L15/46Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A61L29/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/252Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
    • A61L2300/254Enzymes, proenzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404Biocides, antimicrobial agents, antiseptic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/424Anti-adhesion agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/45Mixtures of two or more drugs, e.g. synergistic mixtures

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Materials Engineering (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Zoology (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Environmental Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SG10201400926VA 2009-03-31 2010-03-31 Inhibition of biofilm organisms SG10201400926VA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16539609P 2009-03-31 2009-03-31
GBGB0905451.1A GB0905451D0 (en) 2009-03-31 2009-03-31 Biofilms

Publications (1)

Publication Number Publication Date
SG10201400926VA true SG10201400926VA (en) 2014-10-30

Family

ID=40671951

Family Applications (2)

Application Number Title Priority Date Filing Date
SG2011064417A SG174278A1 (en) 2009-03-31 2010-03-31 Inhibition of biofilm organisms
SG10201400926VA SG10201400926VA (en) 2009-03-31 2010-03-31 Inhibition of biofilm organisms

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG2011064417A SG174278A1 (en) 2009-03-31 2010-03-31 Inhibition of biofilm organisms

Country Status (21)

Country Link
US (3) US9339525B2 (en)
EP (1) EP2413949B1 (en)
JP (1) JP5727994B2 (en)
KR (1) KR101852784B1 (en)
CN (2) CN102387794B (en)
AU (2) AU2010231136B2 (en)
BR (1) BRPI1012219C1 (en)
CA (1) CA2755878C (en)
CY (1) CY1121175T1 (en)
GB (1) GB0905451D0 (en)
IL (1) IL215369B2 (en)
MX (1) MX358018B (en)
NZ (1) NZ595037A (en)
PL (1) PL2413949T3 (en)
RU (1) RU2548786C2 (en)
SG (2) SG174278A1 (en)
SI (1) SI2413949T1 (en)
TR (1) TR201821161T4 (en)
UA (1) UA106743C2 (en)
WO (1) WO2010112848A2 (en)
ZA (1) ZA201107140B (en)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2463181B (en) 2007-05-14 2013-03-27 Univ New York State Res Found Induction of a physiological dispersion response in bacterial cells in a biofilm
GB0905451D0 (en) * 2009-03-31 2009-05-13 Novabiotics Ltd Biofilms
TWI403330B (en) * 2010-03-29 2013-08-01 Rise technology co ltd Low hemolysis antibacterial peptide pharmaceutical compositions and use thereof
GB201016733D0 (en) * 2010-10-05 2010-11-17 Novabiotics Ltd Compounds and their use
US9534223B2 (en) * 2010-04-27 2017-01-03 Lysando Ag Method of reducing biofilms
GB201021186D0 (en) * 2010-12-14 2011-01-26 Novabiotics Ltd Composition
AU2012253379A1 (en) 2011-05-12 2013-11-21 Healthpoint, Ltd. Wound debridement compositions containing seaprose and methods of wound treatment using same
TWI415572B (en) 2011-06-17 2013-11-21 Univ Chang Gung Inhibition of biofilm formation by 1,2,3,4,6-penta-o-galloyl-d-glucopyranose
US20140315789A1 (en) * 2011-11-23 2014-10-23 Newsouth Innovations Pty Limited Antimicrobial peptides and uses thereof
CA2867903C (en) 2012-03-23 2023-02-14 Amicrobe, Inc. Compositions and uses of antimicrobial materials with tissue-compatible properties
MX2014013745A (en) * 2012-05-11 2016-05-05 Smith & Nephew Inc Use of seaprose to remove bacterial biofilm.
WO2014016979A1 (en) * 2012-07-27 2014-01-30 住友重機械工業株式会社 Microbial activity modulator and method of modulating microbe activity
EP3038638A4 (en) * 2013-08-27 2017-09-13 The University Of British Columbia Small cationic anti-biofilm and idr peptides
GB201405891D0 (en) * 2014-04-02 2014-05-14 Novabiotics Ltd Modified antimicrobial peptides
GB201416727D0 (en) * 2014-09-22 2014-11-05 Novabiotics Ltd Use
US20160102052A1 (en) * 2014-09-22 2016-04-14 Novabiotics Limited Use of Cysteamine in Treating Infections caused by Yeasts/Moulds
GB201510077D0 (en) * 2015-06-10 2015-07-22 Novabiotics Ltd Use
US11103547B2 (en) 2016-02-04 2021-08-31 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Methods for disrupting biofilms
WO2017140770A1 (en) * 2016-02-19 2017-08-24 Forschungszentrum Borstel Leibniz-Zentrum Für Medizin Und Biowissenschaften Means and methods for treating bacterial infections
US20190071706A1 (en) 2016-04-04 2019-03-07 University Of Virginia Patent Foundation Compositions and methods for preventing and treating disease
EP3241570A1 (en) * 2016-05-02 2017-11-08 Institut National De La Sante Et De La Recherche Medicale (Inserm) Polypeptide and hyaluronic acid coatings
CN109789191B (en) * 2016-05-12 2023-08-01 宾夕法尼亚州立大学托管会 Compositions and methods for inhibiting biofilm deposition and production
WO2017212239A1 (en) * 2016-06-07 2017-12-14 Novabiotics Limited Treatment of drug-resistant microbial infections
US11628207B2 (en) 2016-07-27 2023-04-18 Smith & Nephew, Inc. Use of thermolysin to reduce or eliminate bacterial biofilms from surfaces
FI3554491T3 (en) 2016-12-15 2023-04-26 Zambon Spa N-acetylcysteine for use as antibacterial agent
US20200016231A1 (en) * 2016-12-22 2020-01-16 Whiteley Corporation Pty Ltd Biofilm disrupting composition
KR102548671B1 (en) * 2017-01-05 2023-06-28 코르메딕스, 인코포레이티드 Antimicrobial compositions comprising antimicrobial hydrogels effective against mature biofilms
EP3573622B1 (en) 2017-01-30 2023-10-18 Smith & Nephew, Inc. Synergistic combination of thermolysin and an antibacterial agent to reduce or eliminate bacterial biofilms from surfaces
AU2018249552A1 (en) 2017-04-06 2019-10-31 Amicrobe, Inc. Compositions and uses of locally-applied antimicrobial synthetic cationic polypeptide(s) with enhanced performance and safety
RU2664708C1 (en) * 2017-06-08 2018-08-21 Сергей Иванович Черныш Method of destroying and preventing formation of bacterial biofilms by complex of antimicrobial peptides of insects
CN108048359B (en) * 2017-12-27 2020-12-01 广州立白企业集团有限公司 Culture method of dental plaque biomembrane model, optimized biomembrane viable count method and application
EP3765057A4 (en) * 2018-03-13 2022-01-05 Peptilogics, Inc. Treatment of implants with engineered antimicrobial amphiphilic peptides
CN108753632A (en) * 2018-05-25 2018-11-06 安徽中医药大学 A method of dissolving candida albicans biofilm extracellular matrix
US11541105B2 (en) 2018-06-01 2023-01-03 The Research Foundation For The State University Of New York Compositions and methods for disrupting biofilm formation and maintenance
EP3866775A1 (en) * 2018-10-17 2021-08-25 Novabiotics Limited Dosage regime
CN110402928A (en) * 2019-08-08 2019-11-05 杭州博菲医疗器械有限公司 A kind of bacteria resistance function liquid and the conduit tube component using the bacteria resistance function liquid
CN110583697B (en) * 2019-09-20 2021-04-06 浙江工商大学 Efficient chemical biological agent for removing pseudomonas aeruginosa biofilm and application thereof
CN111675751B (en) * 2020-04-08 2022-06-14 天津医科大学口腔医院 Antibacterial peptide and application thereof
GB202010268D0 (en) * 2020-07-03 2020-08-19 Novabiotics Ltd Nail formulations and treatment regimes

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1055560B (en) * 1974-05-02 1982-01-11 Istituto Chemioterapico PYRIMIDINE DERIVATIVES AND RELATED COMPOSITIONS FOR THE TREATMENT OF VIRAL INFECTIONS
US6475434B1 (en) * 1998-12-07 2002-11-05 Baylor College Of Medicine Composition and methods for preventing and removing biofilm embedded microorganisms from the surface of medical devices
ITMI20021881A1 (en) * 2002-09-04 2004-03-05 Zambon Spa PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF INFECTIONS FROM URINARY PATHOGENS.
GB2398497A (en) * 2003-02-19 2004-08-25 Walcom Animal Science Composition for improving immunity of animals
EP1927597B1 (en) * 2004-08-18 2016-11-02 Novabiotics Limited Antibacterial peptides
US20070093894A1 (en) * 2005-10-25 2007-04-26 Baylor College Of Medicine Incorporation of antimicrobial combinations onto devices to reduce infection
ZA200805191B (en) * 2005-11-28 2009-08-26 Hk Omega Biopharma Ltd Materials and methods for treating viral infections with a cysteamine compound
AR057623A1 (en) * 2005-11-28 2007-12-05 Omega Bio Pharma H K Ltd MATERIALS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS
GB0702021D0 (en) * 2007-02-02 2007-03-14 Novabiotics Ltd Peptides and their use
US20100151042A1 (en) * 2007-05-25 2010-06-17 Hao Yi Liang Materials and Methods for Treating Influenza Infections
US20090209650A1 (en) * 2008-02-17 2009-08-20 Francis Chi Materials and Methods for Improving the health of Shrimp
GB0905451D0 (en) * 2009-03-31 2009-05-13 Novabiotics Ltd Biofilms
GB201021186D0 (en) * 2010-12-14 2011-01-26 Novabiotics Ltd Composition
US20160106689A1 (en) * 2014-09-22 2016-04-21 Novabiotics Limited Use
US20160102052A1 (en) * 2014-09-22 2016-04-14 Novabiotics Limited Use of Cysteamine in Treating Infections caused by Yeasts/Moulds

Also Published As

Publication number Publication date
AU2016210742B2 (en) 2017-08-10
KR20120003893A (en) 2012-01-11
EP2413949B1 (en) 2018-10-10
AU2010231136A1 (en) 2011-09-29
IL215369B2 (en) 2023-02-01
CN102387794A (en) 2012-03-21
SI2413949T1 (en) 2019-02-28
CY1121175T1 (en) 2020-05-29
UA106743C2 (en) 2014-10-10
US20160206575A1 (en) 2016-07-21
BRPI1012219B8 (en) 2020-05-12
PL2413949T3 (en) 2019-04-30
AU2010231136B2 (en) 2016-08-04
CA2755878A1 (en) 2010-10-07
US20190175528A1 (en) 2019-06-13
CN102387794B (en) 2015-11-25
WO2010112848A3 (en) 2011-01-27
SG174278A1 (en) 2011-10-28
TR201821161T4 (en) 2019-01-21
CA2755878C (en) 2018-04-24
BRPI1012219C1 (en) 2021-05-25
BRPI1012219A2 (en) 2016-03-29
AU2016210742A1 (en) 2016-08-25
JP5727994B2 (en) 2015-06-03
MX2011010258A (en) 2011-10-19
US20120189682A1 (en) 2012-07-26
GB0905451D0 (en) 2009-05-13
NZ595037A (en) 2013-07-26
CN104257645A (en) 2015-01-07
IL215369B (en) 2022-10-01
EP2413949A2 (en) 2012-02-08
KR101852784B1 (en) 2018-04-30
WO2010112848A2 (en) 2010-10-07
JP2012522037A (en) 2012-09-20
US9339525B2 (en) 2016-05-17
ZA201107140B (en) 2012-06-27
IL215369A (en) 2013-02-03
MX358018B (en) 2018-08-02
RU2548786C2 (en) 2015-04-20

Similar Documents

Publication Publication Date Title
ZA201107140B (en) Inhibition of biofilm organisms
ZA201700326B (en) Inhibitors of beta-secretase
GB0919097D0 (en) Treatment of hard surfaces
ZA201102604B (en) Alkylcyclohexylethers of dihydrotetraazabenzoazulenes
HK1171624A1 (en) Inhibitors of cognitive decline
HK1167323A1 (en) Inhibitors of cognitive decline
ZA201007418B (en) Arrangement for neutralisation of microorganisms
HK1160925A1 (en) Use of athepsin
GB0907886D0 (en) Corrosion inhibitor
EP2296476A4 (en) Inhibitors of bacterial biofilm formation
GB0916510D0 (en) Deposition of materials
IL217756A0 (en) Inhibitors of jnk
EG26530A (en) Composition for decreasing hardness of water
EP2418208A4 (en) Inhibitor for elevation of gip level
HRP20190034T1 (en) Inhibition of biofilm organisms
GB0908609D0 (en) New use of isoQC inhibitors
GB0915468D0 (en) Get me out of here
HU0800656D0 (en) Effective use of tea-composition
GB0905280D0 (en) Novel uses of VEGFxxxb
GB0715788D0 (en) Inhibition of corrosion
GB0912788D0 (en) Corrosion inhibitor
GB0911084D0 (en) New use of statins
GB0914742D0 (en) Enzyme inhibition
GB0914739D0 (en) Enzyme inhibition