BRPI1010024A2 - derivados de aminopirrolidinona e uso dos mesmos - Google Patents
derivados de aminopirrolidinona e uso dos mesmosInfo
- Publication number
- BRPI1010024A2 BRPI1010024A2 BRPI1010024A BRPI1010024A BRPI1010024A2 BR PI1010024 A2 BRPI1010024 A2 BR PI1010024A2 BR PI1010024 A BRPI1010024 A BR PI1010024A BR PI1010024 A BRPI1010024 A BR PI1010024A BR PI1010024 A2 BRPI1010024 A2 BR PI1010024A2
- Authority
- BR
- Brazil
- Prior art keywords
- aminopyrrolidinone
- derivatives
- aminopyrrolidinone derivatives
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US18438609P | 2009-06-05 | 2009-06-05 | |
US29502310P | 2010-01-14 | 2010-01-14 | |
PCT/US2010/037582 WO2010141932A1 (en) | 2009-06-05 | 2010-06-07 | Aminopyrrolidinone derivatives and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI1010024A2 true BRPI1010024A2 (pt) | 2019-09-24 |
Family
ID=42635266
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI1010024A BRPI1010024A2 (pt) | 2009-06-05 | 2010-06-07 | derivados de aminopirrolidinona e uso dos mesmos |
Country Status (12)
Country | Link |
---|---|
US (2) | US8252829B2 (pt) |
EP (1) | EP2438059A1 (pt) |
JP (1) | JP2012529432A (pt) |
CN (1) | CN102548986A (pt) |
AU (1) | AU2010256360A1 (pt) |
BR (1) | BRPI1010024A2 (pt) |
CA (1) | CA2764387A1 (pt) |
IL (1) | IL216768A0 (pt) |
MX (1) | MX2011013016A (pt) |
SG (1) | SG176628A1 (pt) |
WO (1) | WO2010141932A1 (pt) |
ZA (1) | ZA201109034B (pt) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10164139A1 (de) | 2001-12-27 | 2003-07-10 | Bayer Ag | 2-Heteroarylcarbonsäureamide |
WO2008022349A2 (en) | 2006-08-18 | 2008-02-21 | Armagen Technologies, Inc. | Agents for blood-brain barrier delivery |
US20100312105A1 (en) * | 2007-10-31 | 2010-12-09 | Alseres Pharmaceuticals, Inc. | Methods for diagnosing and monitoring treatment of lewy body dementia by assessing dopamine transporter level |
CA3017886A1 (en) | 2008-11-19 | 2010-05-27 | Envivo Pharmaceuticals, Inc. | Treatment of cognitive disorders with (r)-7-chloro-n-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide and pharmaceutically acceptable salts thereof |
CN102802620A (zh) * | 2009-05-11 | 2012-11-28 | 英维沃医药有限公司 | 使用某种α-7烟酸受体与乙酰胆碱酯酶抑制剂结合治疗认知障碍 |
EP2485761B1 (en) | 2009-10-09 | 2019-02-27 | Armagen, Inc. | Methods and compositions for increasing iduronate 2-sulfatase activity in the cns |
WO2011146511A1 (en) | 2010-05-17 | 2011-11-24 | Envivo Pharmaceuticals, Inc. | A crystalline form of (r)-7-chloro-n-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide hydrochloride monohydrate |
EA027748B1 (ru) * | 2012-04-04 | 2017-08-31 | Тева Фармасьютикалз Интернэшнл Гмбх | Применение придопидина в комбинации с тетрабеназином для лечения двигательных нарушений и ожирения |
AU2013259871A1 (en) | 2012-05-08 | 2014-11-20 | Forum Pharmaceuticals Inc. | Methods of maintaining, treating or improving cognitive function |
PL3292875T3 (pl) * | 2012-06-19 | 2020-11-16 | University Of Florida Research Foundation, Inc. | Kompozycje i sposoby leczenia chorób |
US8818117B2 (en) * | 2012-07-19 | 2014-08-26 | Sony Corporation | Method and apparatus for compressing Z-stack microscopy images |
JP6194003B2 (ja) | 2012-10-09 | 2017-09-06 | ザ プロクター アンド ギャンブル カンパニー | 有益剤及びこれを含む組成物の特定又は評価方法 |
CN104703585A (zh) | 2012-10-09 | 2015-06-10 | 宝洁公司 | 鉴定协同化妆品组合的方法 |
JP6407029B2 (ja) * | 2012-12-13 | 2018-10-17 | 新田ゼラチン株式会社 | 筋芽細胞分化促進剤 |
US10906981B2 (en) * | 2013-07-19 | 2021-02-02 | The Regents Of The University Of California | Compositions and methods related to structures that cross the blood brain barrier |
JP6746945B2 (ja) * | 2015-06-30 | 2020-08-26 | ソニー株式会社 | 情報処理装置、情報処理システム及び情報処理方法 |
US10407023B2 (en) * | 2017-01-30 | 2019-09-10 | Ford Global Technologies, Llc | Remote starting of engines via vehicle keypads |
JP6958860B2 (ja) * | 2017-11-07 | 2021-11-02 | 学校法人自治医科大学 | ミトコンドリアの機能障害の改善剤、及びミトコンドリアの機能障害に起因する疾患又は症状の予防又は治療薬、並びにそれらの用途 |
CN114681472B (zh) * | 2019-03-13 | 2023-06-30 | 中国人民解放军军事科学院军事医学研究院 | 氨基葡萄糖及其衍生物作为抗病毒药物的应用 |
CN112945913A (zh) * | 2019-12-10 | 2021-06-11 | 中国科学院大连化学物理研究所 | 一种萘酰亚胺类荧光探针在脂滴成像领域中的应用 |
Family Cites Families (90)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4902505A (en) | 1986-07-30 | 1990-02-20 | Alkermes | Chimeric peptides for neuropeptide delivery through the blood-brain barrier |
US5004697A (en) | 1987-08-17 | 1991-04-02 | Univ. Of Ca | Cationized antibodies for delivery through the blood-brain barrier |
US4939174A (en) | 1988-02-26 | 1990-07-03 | Shashoua Victor E | Appetite suppression with dopamine-fatty acid conjugates |
US6107499A (en) | 1988-02-26 | 2000-08-22 | Neuromedica, Inc. | Dopamine analog amide |
US4933324A (en) | 1988-02-26 | 1990-06-12 | Shashoua Victor E | Fatty acid-neuroactive drug conjugate as a prodrug |
US5994392A (en) | 1988-02-26 | 1999-11-30 | Neuromedica, Inc. | Antipsychotic prodrugs comprising an antipsychotic agent coupled to an unsaturated fatty acid |
US5025001A (en) | 1988-06-15 | 1991-06-18 | Brigham And Women's Hospital | S-nitroso derivatives of ACE inhibitors and the use thereof |
US5527527A (en) | 1989-09-07 | 1996-06-18 | Alkermes, Inc. | Transferrin receptor specific antibody-neuropharmaceutical agent conjugates |
US5977307A (en) | 1989-09-07 | 1999-11-02 | Alkermes, Inc. | Transferrin receptor specific ligand-neuropharmaceutical agent fusion proteins |
US5130330A (en) | 1990-01-31 | 1992-07-14 | G. D. Searle & Co. | Nitrogen-containing cyclohetero cycloalkylaminoaryl derivatives for cns disorders |
US5268164A (en) | 1990-04-23 | 1993-12-07 | Alkermes, Inc. | Increasing blood-brain barrier permeability with permeabilizer peptides |
US5112596A (en) | 1990-04-23 | 1992-05-12 | Alkermes, Inc. | Method for increasing blood-brain barrier permeability by administering a bradykinin agonist of blood-brain barrier permeability |
ATE159009T1 (de) | 1991-05-10 | 1997-10-15 | Rhone Poulenc Rorer Int | Bis mono- und bicyclische aryl- und heteroarylderivate mit inhibierender wirkung auf die egf und/oder pdgf-rezeptor tyrosinkinase |
EP0524595A1 (en) | 1991-07-23 | 1993-01-27 | Schering Corporation | Substituted beta-lactam compounds useful as hypocholesterolemic agents and processes for the preparation thereof |
GB2267966A (en) | 1992-06-17 | 1993-12-22 | Merck & Co Inc | A fluorescence assay for farnesyl protein transferase activity |
BR9509994A (pt) | 1994-12-13 | 1997-12-30 | Corvas Int Inc | Derivados heterocíclicos aromáticos como inibidores de enzimas |
AU5772396A (en) | 1995-05-19 | 1996-11-29 | Chiroscience Limited | 3,4-disubstituted-phenylsulphonamides and their therapeutic use |
US6011029A (en) | 1996-02-26 | 2000-01-04 | Bristol-Myers Squibb Company | Inhibitors of farnesyl protein transferase |
US6063930A (en) | 1996-04-03 | 2000-05-16 | Merck & Co., Inc. | Substituted imidazole compounds useful as farnesyl-protein transferase inhibitors |
AU715603B2 (en) | 1996-04-03 | 2000-02-03 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
US6001835A (en) | 1996-04-03 | 1999-12-14 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
EP0937073A2 (en) | 1996-10-11 | 1999-08-25 | Cor Therapeutics, Inc. | Selective factor xa inhibitors |
JPH10215175A (ja) | 1996-11-29 | 1998-08-11 | Sony Corp | Pll回路及び信号再生装置 |
CN1246847A (zh) | 1996-12-23 | 2000-03-08 | 杜邦药品公司 | 作为Xa因子抑制剂的含氮杂芳族化合物 |
US6093737A (en) | 1996-12-30 | 2000-07-25 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
CA2293713C (en) | 1997-06-17 | 2006-12-05 | Schering Corporation | Bispyrido-cycloheptane compounds useful for inhibition of farnesyl protein transferase |
US5972898A (en) | 1998-03-27 | 1999-10-26 | Abbott Laboratories | 3',3-N-bis-substituted macrolide LHRH antagonists |
US6437146B1 (en) | 1998-09-25 | 2002-08-20 | Fujisawa Pharmaceutical Co., Ltd. | Oxazole compounds as prostaglandin e2 agonists or antagonists |
CA2362778A1 (en) | 1999-03-03 | 2000-09-08 | Merck & Co., Inc. | Inhibitors of prenyl-protein transferase |
AU6016200A (en) | 1999-07-16 | 2001-02-05 | Sankyo Company Limited | Coumarone analogues |
US20030191279A1 (en) | 1999-08-27 | 2003-10-09 | Goldstein Steven Wayne | Urea derivatives useful as anticancer agents |
EP1214326A1 (en) | 1999-09-09 | 2002-06-19 | Merck & Co., Inc. | Inhibitors of prenyl-protein transferase |
WO2001017992A1 (en) | 1999-09-09 | 2001-03-15 | Merck & Co., Inc. | Inhibitors of prenyl-protein transferase |
US6844367B1 (en) | 1999-09-17 | 2005-01-18 | Millennium Pharmaceuticals, Inc. | Benzamides and related inhibitors of factor Xa |
EP1216231A2 (en) | 1999-09-17 | 2002-06-26 | Millennium Pharmaceuticals, Inc. | INHIBITORS OF FACTOR Xa |
US7087597B1 (en) | 1999-10-12 | 2006-08-08 | Takeda Pharmaceutical Company Limited | Pyrimidine 5-carboxamide compounds, process for producing the same and use thereof |
US6713476B2 (en) | 2000-04-03 | 2004-03-30 | Dupont Pharmaceuticals Company | Substituted cycloalkyls as inhibitors of a beta protein production |
AU2001273040A1 (en) | 2000-06-27 | 2002-01-08 | Du Pont Pharmaceuticals Company | Factor xa inhibitors |
JP2002275064A (ja) | 2001-01-15 | 2002-09-25 | Sankyo Co Ltd | クロマン類縁体を含有する医薬 |
AU2002303264A1 (en) | 2001-04-09 | 2002-10-21 | Bristol-Myers Squibb Company | Fused heterocyclic inhibitors of factor xa |
GB2377933A (en) | 2001-07-06 | 2003-01-29 | Bayer Ag | Succinic acid derivatives useful as integrin antagonists |
AU2003205570A1 (en) | 2002-01-10 | 2003-07-24 | Boehringer Ingelheim Pharma Gmbh And Co. Kg | Combination of mtp inhibitors or apob secretion inhibitors with fibrates for use as drugs |
TW200812986A (en) | 2002-08-09 | 2008-03-16 | Nps Pharma Inc | New compounds |
US7074809B2 (en) | 2002-08-09 | 2006-07-11 | Astrazeneca Ab | Compounds |
US7294642B2 (en) | 2002-09-06 | 2007-11-13 | Elan Pharmaceuticals, Inc. | 1,3-Diamino-2-hydroxypropane pro-drug derivatives |
PL376154A1 (en) | 2002-09-18 | 2005-12-27 | Ono Pharmaceutical Co, Ltd. | Triazaspiro[5.5]undecane derivatives and drugs comprising the same as the active ingredient |
AU2003275632A1 (en) | 2002-10-25 | 2004-05-13 | Mitsubishi Pharma Corporation | N-oxide compounds |
WO2005012221A1 (ja) | 2003-08-04 | 2005-02-10 | Ono Pharmaceutical Co., Ltd. | ジフェニルエーテル化合物、その製造方法および用途 |
GB0325956D0 (en) | 2003-11-06 | 2003-12-10 | Addex Pharmaceuticals Sa | Novel compounds |
WO2005077373A2 (en) | 2004-02-03 | 2005-08-25 | Astrazeneca Ab | Treatment of gastro-esophageal reflux disease (gerd) |
WO2005077345A1 (en) | 2004-02-03 | 2005-08-25 | Astrazeneca Ab | Compounds for the treatment of gastro-esophageal reflux disease |
WO2005077368A2 (en) | 2004-02-03 | 2005-08-25 | Astrazeneca Ab | Treatment of gastro-esophageal reflux disease (gerd) |
US20050197336A1 (en) | 2004-03-08 | 2005-09-08 | Miikana Therapeutics Corporation | Inhibitors of histone deacetylase |
US7345043B2 (en) | 2004-04-01 | 2008-03-18 | Miikana Therapeutics | Inhibitors of histone deacetylase |
US20060074103A1 (en) | 2004-10-06 | 2006-04-06 | Corte James R | Cyclic beta-amino acid derivatives as factor Xa inhibitors |
EP1656931A1 (en) * | 2004-11-15 | 2006-05-17 | Exonhit Therapeutics SA | Compounds which inhibits protein prenylation ( e.g. geranylgeranyltransferase or farnesyltransferase inhibitors) for treating Parkinson's disease |
WO2006063010A2 (en) | 2004-12-08 | 2006-06-15 | Nuada, Llc | Compounds and methods of use thereof |
CA2589830A1 (en) | 2005-01-05 | 2006-07-13 | Rigel Pharmaceuticals, Inc. | Ubiquitin ligase inhibitors |
US7511077B2 (en) | 2005-02-09 | 2009-03-31 | Neuromed Pharmaceuticals Ltd. | Diamine calcium channel blockers |
EP1864971A4 (en) | 2005-03-31 | 2010-02-10 | Takeda Pharmaceutical | PROPHYLACTIC / THERAPEUTIC AGENT AGAINST DIABETES |
GB0510139D0 (en) | 2005-05-18 | 2005-06-22 | Addex Pharmaceuticals Sa | Novel compounds B1 |
WO2007029121A2 (en) | 2005-07-21 | 2007-03-15 | Galderma Research & Development | Novel cyclopent-2-en-1-one derivatives which are ppar receptor modulators, and use thereof in pharmaceutical or cosmetic compositions |
AU2006274733B2 (en) | 2005-07-30 | 2010-09-16 | Astrazeneca Ab | Imidazolyl-pyrimidine compounds for use in the treatment of proliferative disorders |
WO2007100351A2 (en) | 2005-09-13 | 2007-09-07 | Teva Gyogyszergyar Zartkoruen Mukodo Reszvenytarsasag | Process for preparing simvastatin and intermediates thereof |
US20070129437A1 (en) | 2005-12-06 | 2007-06-07 | Ferenc Korodi | Process for preparing simvastatin and intermediates thereof |
WO2007070556A2 (en) | 2005-12-12 | 2007-06-21 | Genelabs Technologies, Inc. | N-(6-membered aromatic ring)-amido anti-viral compounds |
CA2633569A1 (en) | 2005-12-12 | 2007-06-21 | Genelabs Technologies, Inc. | N-(5-membered heteroaromatic ring)-amido anti-viral compounds |
CA2637024C (en) | 2006-01-30 | 2013-05-14 | Transtech Pharma, Inc. | Substituted imidazole derivatives, compositions, and methods of use as ptpase inhibitors |
PE20071025A1 (es) | 2006-01-31 | 2007-10-17 | Mitsubishi Tanabe Pharma Corp | Compuesto amina trisustituido |
CA2691214A1 (en) | 2006-06-09 | 2007-12-21 | Kemia, Inc. | Therapy using cytokine inhibitors |
CA2656067C (en) | 2006-06-23 | 2014-08-12 | Radius Health, Inc. | Treatment of vasomotor symptoms with selective estrogen receptor modulators |
AU2007269830A1 (en) | 2006-06-29 | 2008-01-10 | Schering Corporation | Substituted bicyclic and tricyclic thrombin receptor antagonists |
JP2010510246A (ja) | 2006-11-21 | 2010-04-02 | スミスクライン ビーチャム コーポレーション | アミド抗ウイルス化合物 |
BRPI0719379A2 (pt) | 2006-11-24 | 2014-02-11 | Ac Immune Sa | Composto, composição farmacêutica, uso de composto, mistura, métodos para coletar dados para o diagnóstico de uma doença ou condição associada com amilóide em uma amostra ou um paciente, para determinar a extensão da carga de placa amiloidogênica em um tecido e/ou um fluido corporal, para coletar dados para determinar a predisposição a uma doença ou condição associada com amilóide em um paciente, para coletar dados para monitorar a doença residual mínima em um paciente seguindo o tratamento com um anticorpo ou uma composição de vacina e para coletar dados para predizer a responsividade de um paciente sendo tratado com um anticorpo ou uma composição de vacina, e, kit de teste |
WO2008091670A2 (en) | 2007-01-24 | 2008-07-31 | Polyera Corporation | Organic semiconductor materials and precursors thereof |
GB0707051D0 (en) | 2007-04-12 | 2007-05-30 | Istituto Di Ricerche D Biolog | Antiviral agents |
US8975259B2 (en) | 2007-04-27 | 2015-03-10 | University Of Rochester | Compositions and methods for inhibiting G protein signaling |
US20090012091A1 (en) | 2007-07-02 | 2009-01-08 | Kinagen, Inc. | Oximide derivatives and their therapeutical application |
JP4834699B2 (ja) | 2007-07-30 | 2011-12-14 | 田辺三菱製薬株式会社 | 医薬組成物 |
JP4846769B2 (ja) | 2007-07-30 | 2011-12-28 | 田辺三菱製薬株式会社 | 医薬組成物 |
JP2011500584A (ja) | 2007-10-10 | 2011-01-06 | ケミエテック,エルエルシ− | Crth2受容体拮抗薬としての複素環化合物 |
US8907095B2 (en) | 2007-10-22 | 2014-12-09 | Merck Sharp & Dohme Corp. | Bicyclic heterocycle derivatives and their use as modulators of the activity of GPR119 |
JP5544296B2 (ja) | 2007-11-16 | 2014-07-09 | ライジェル ファーマシューティカルズ, インコーポレイテッド | 代謝障害のためのカルボキサミド、スルホンアミド、およびアミン化合物 |
EP2268636A1 (en) | 2007-12-11 | 2011-01-05 | Schering Corporation | Gamma secretase modulators |
TWI447099B (zh) | 2008-01-29 | 2014-08-01 | Nissan Chemical Ind Ltd | Aryl sulfonic acid compounds and the use of electron acceptables |
KR101331032B1 (ko) | 2008-07-30 | 2013-11-19 | 삼성전자주식회사 | 가상화 환경과 결합된 어플리케이션 실행 방법 |
EP2237405B1 (en) | 2009-03-31 | 2013-02-20 | STMicroelectronics Srl | Control device for the change of the driving modality of an electromagnetic load |
US8473905B1 (en) | 2009-09-30 | 2013-06-25 | Emc Corporation | Managing user interface characteristics in displaying data storage systems information |
JP5646195B2 (ja) | 2010-03-30 | 2014-12-24 | 富士フイルム株式会社 | インクジェット記録装置及び断熱処理方法 |
TWI437908B (zh) | 2011-05-17 | 2014-05-11 | Leadtrend Tech Corp | 具電流平衡功能的驅動電路 |
-
2010
- 2010-06-07 CN CN2010800350077A patent/CN102548986A/zh active Pending
- 2010-06-07 MX MX2011013016A patent/MX2011013016A/es not_active Application Discontinuation
- 2010-06-07 SG SG2011089018A patent/SG176628A1/en unknown
- 2010-06-07 WO PCT/US2010/037582 patent/WO2010141932A1/en active Application Filing
- 2010-06-07 EP EP10724958A patent/EP2438059A1/en not_active Withdrawn
- 2010-06-07 JP JP2012514220A patent/JP2012529432A/ja not_active Withdrawn
- 2010-06-07 BR BRPI1010024A patent/BRPI1010024A2/pt not_active IP Right Cessation
- 2010-06-07 AU AU2010256360A patent/AU2010256360A1/en not_active Abandoned
- 2010-06-07 US US12/795,065 patent/US8252829B2/en not_active Expired - Fee Related
- 2010-06-07 CA CA2764387A patent/CA2764387A1/en not_active Abandoned
-
2011
- 2011-12-04 IL IL216768A patent/IL216768A0/en unknown
- 2011-12-08 ZA ZA2011/09034A patent/ZA201109034B/en unknown
-
2012
- 2012-07-13 US US13/548,363 patent/US20130289086A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
IL216768A0 (en) | 2012-02-29 |
AU2010256360A1 (en) | 2012-01-12 |
WO2010141932A1 (en) | 2010-12-09 |
US8252829B2 (en) | 2012-08-28 |
CN102548986A (zh) | 2012-07-04 |
ZA201109034B (en) | 2013-02-27 |
CA2764387A1 (en) | 2010-12-09 |
JP2012529432A (ja) | 2012-11-22 |
MX2011013016A (es) | 2012-04-20 |
US20130289086A1 (en) | 2013-10-31 |
SG176628A1 (en) | 2012-01-30 |
EP2438059A1 (en) | 2012-04-11 |
US20110021590A1 (en) | 2011-01-27 |
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