BRPI0924844A2 - derivados de azacarbolinas 9h-pirrol[2,3-b:5,4-c']dipiridina, sua preparação e sua utilização terapêutica. - Google Patents
derivados de azacarbolinas 9h-pirrol[2,3-b:5,4-c']dipiridina, sua preparação e sua utilização terapêutica.Info
- Publication number
- BRPI0924844A2 BRPI0924844A2 BRPI0924844A BRPI0924844A BRPI0924844A2 BR PI0924844 A2 BRPI0924844 A2 BR PI0924844A2 BR PI0924844 A BRPI0924844 A BR PI0924844A BR PI0924844 A BRPI0924844 A BR PI0924844A BR PI0924844 A2 BRPI0924844 A2 BR PI0924844A2
- Authority
- BR
- Brazil
- Prior art keywords
- azacarbolines
- dipyridine
- pyrrol
- derivatives
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0901368A FR2943674B1 (fr) | 2009-03-24 | 2009-03-24 | Derives d'azacarbolines,leur preparation et leur utilisation therapeutique |
| FR0956944A FR2950891B1 (fr) | 2009-10-06 | 2009-10-06 | Derives d'azacarbolines 9h-pyrrolo[2,3-b:5,4-c']dipyridine, leur preparation et leur utilisation therapeutique |
| PCT/FR2009/052330 WO2010109084A2 (fr) | 2009-03-24 | 2009-11-30 | DERIVES D'AZACARBOLINES 9H-PYRROLO[2,3-b:5,4-c']DIPYRIDINE, LEUR PREPARATION ET LEUR UTILISATION THERAPEUTIQUE |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0924844A2 true BRPI0924844A2 (pt) | 2016-01-26 |
Family
ID=42101692
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0924844A BRPI0924844A2 (pt) | 2009-03-24 | 2009-11-30 | derivados de azacarbolinas 9h-pirrol[2,3-b:5,4-c']dipiridina, sua preparação e sua utilização terapêutica. |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20120208809A1 (de) |
| EP (1) | EP2411389A2 (de) |
| JP (1) | JP2012521394A (de) |
| KR (1) | KR20110130504A (de) |
| CN (1) | CN102365282A (de) |
| AR (1) | AR073431A1 (de) |
| AU (1) | AU2009342734A1 (de) |
| BR (1) | BRPI0924844A2 (de) |
| CA (1) | CA2756152A1 (de) |
| IL (1) | IL215286A0 (de) |
| MX (1) | MX2011010062A (de) |
| RU (1) | RU2011142791A (de) |
| SG (1) | SG174903A1 (de) |
| TW (1) | TW201035097A (de) |
| UY (1) | UY32275A (de) |
| WO (1) | WO2010109084A2 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2706059A1 (de) * | 2008-06-11 | 2014-03-12 | Genentech, Inc. | Diazacarbazole und Verwendungsverfahren |
| US20110183938A1 (en) * | 2009-12-16 | 2011-07-28 | Genentech, Inc. | 1,7-diazacarbazoles and methods of use |
| JO3438B1 (ar) | 2011-04-13 | 2019-10-20 | Epizyme Inc | مركبات بنزين مستبدلة بأريل أو أريل غير متجانس |
| CN102432472A (zh) * | 2011-11-03 | 2012-05-02 | 浙江工业大学 | 一种2，2-二氟丙烷-1，3-二胺的制备方法 |
| KR101561330B1 (ko) | 2012-09-19 | 2015-10-16 | 주식회사 두산 | 인돌로인돌계 유기 발광 화합물 및 이를 이용한 유기 전계 발광 소자 |
| WO2014062732A1 (en) | 2012-10-15 | 2014-04-24 | Epizyme, Inc. | Substituted benzene compounds |
| EP3448375B1 (de) * | 2016-04-25 | 2023-09-27 | Duke University | Benzoylglycinderivate und verfahren zur herstellung und verwendung davon |
| CN112996506A (zh) * | 2018-08-14 | 2021-06-18 | 奥斯特克有限公司 | 吡咯并二吡啶化合物 |
| CN113166058A (zh) | 2018-08-14 | 2021-07-23 | 奥斯特克有限公司 | 氟β-咔啉化合物 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1209158A1 (de) * | 2000-11-18 | 2002-05-29 | Aventis Pharma Deutschland GmbH | Substitutierte beta-Carboline |
| EP1134221A1 (de) * | 2000-03-15 | 2001-09-19 | Aventis Pharma Deutschland GmbH | Substituierte beta-Carboline als lkB-Kinasehemmer |
| EP1896472A1 (de) * | 2005-06-09 | 2008-03-12 | Boehringer Ingelheim International GmbH | Alpha-carboline als cdk-1 inhibitoren |
| US8119655B2 (en) | 2005-10-07 | 2012-02-21 | Takeda Pharmaceutical Company Limited | Kinase inhibitors |
| WO2007110364A1 (en) * | 2006-03-28 | 2007-10-04 | High Point Pharmaceuticals, Llc | Benzothiazoles having histamine h3 receptor activity |
| EP2706059A1 (de) * | 2008-06-11 | 2014-03-12 | Genentech, Inc. | Diazacarbazole und Verwendungsverfahren |
| AR072084A1 (es) * | 2008-06-12 | 2010-08-04 | Sanofi Aventis | Derivados de azacarbolinas, su preparacion y su utilizacion terapeutica como inhibidores de las quinasas pim |
-
2009
- 2009-11-30 KR KR1020117024857A patent/KR20110130504A/ko not_active Application Discontinuation
- 2009-11-30 RU RU2011142791/04A patent/RU2011142791A/ru not_active Application Discontinuation
- 2009-11-30 US US13/258,924 patent/US20120208809A1/en not_active Abandoned
- 2009-11-30 UY UY0001032275A patent/UY32275A/es not_active Application Discontinuation
- 2009-11-30 SG SG2011068889A patent/SG174903A1/en unknown
- 2009-11-30 EP EP09797115A patent/EP2411389A2/de not_active Withdrawn
- 2009-11-30 WO PCT/FR2009/052330 patent/WO2010109084A2/fr active Application Filing
- 2009-11-30 AU AU2009342734A patent/AU2009342734A1/en not_active Abandoned
- 2009-11-30 CN CN2009801583033A patent/CN102365282A/zh active Pending
- 2009-11-30 AR ARP090104599A patent/AR073431A1/es unknown
- 2009-11-30 TW TW098140843A patent/TW201035097A/zh unknown
- 2009-11-30 BR BRPI0924844A patent/BRPI0924844A2/pt not_active IP Right Cessation
- 2009-11-30 MX MX2011010062A patent/MX2011010062A/es not_active Application Discontinuation
- 2009-11-30 CA CA2756152A patent/CA2756152A1/fr not_active Abandoned
- 2009-11-30 JP JP2012501334A patent/JP2012521394A/ja active Pending
-
2011
- 2011-09-21 IL IL215286A patent/IL215286A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2756152A1 (fr) | 2010-09-30 |
| RU2011142791A (ru) | 2013-04-27 |
| JP2012521394A (ja) | 2012-09-13 |
| US20120208809A1 (en) | 2012-08-16 |
| AU2009342734A1 (en) | 2011-10-13 |
| MX2011010062A (es) | 2011-11-18 |
| UY32275A (es) | 2010-06-30 |
| AR073431A1 (es) | 2010-11-03 |
| KR20110130504A (ko) | 2011-12-05 |
| WO2010109084A2 (fr) | 2010-09-30 |
| SG174903A1 (en) | 2011-11-28 |
| EP2411389A2 (de) | 2012-02-01 |
| TW201035097A (en) | 2010-10-01 |
| IL215286A0 (en) | 2011-11-30 |
| WO2010109084A3 (fr) | 2011-01-06 |
| CN102365282A (zh) | 2012-02-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2384 DE 13-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |