BRPI0921469B1 - Proteínas de ligação que inibem a interação com o receptor de vegf-a, composição farmacêutica - Google Patents
Proteínas de ligação que inibem a interação com o receptor de vegf-a, composição farmacêutica Download PDFInfo
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- BRPI0921469B1 BRPI0921469B1 BRPI0921469-0A BRPI0921469A BRPI0921469B1 BR PI0921469 B1 BRPI0921469 B1 BR PI0921469B1 BR PI0921469 A BRPI0921469 A BR PI0921469A BR PI0921469 B1 BRPI0921469 B1 BR PI0921469B1
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| AU2014243418B2 (en) * | 2010-04-30 | 2016-09-22 | Molecular Partners Ag | Modified binding proteins inhibiting the VEGF-A receptor interaction |
| AR081361A1 (es) | 2010-04-30 | 2012-08-29 | Molecular Partners Ag | Proteinas de union modificadas que inhiben la interaccion de receptor del factor de crecimiento endotelial vascular de glicoproteina a vegf-a |
| EP3514169B1 (en) | 2010-11-26 | 2024-03-06 | Molecular Partners AG | Designed repeat proteins binding to serum albumin |
| EA201391607A1 (ru) | 2011-04-29 | 2014-04-30 | Янссен Байотек, Инк. | Связывающие il4/il13 белки с повторами и их применение |
| WO2012172054A1 (en) | 2011-06-16 | 2012-12-20 | Scil Proteins Gmbh | Modified multimeric ubiquitin proteins binding vegf-a |
| CN104039351A (zh) | 2011-10-13 | 2014-09-10 | 阿尔皮奥治疗学股份有限公司 | 用于治疗血管渗漏综合征和癌症的方法 |
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| CN103308673B (zh) | 2012-03-08 | 2017-05-31 | 思芬构技术有限公司 | 用于预测雌性对象中发生心血管事件的风险的方法 |
| CN103308689B (zh) | 2012-03-08 | 2017-04-12 | 思芬构技术有限公司 | 用于预测雌性对象中患上癌症的风险或诊断癌症的方法 |
| CN103308670B (zh) | 2012-03-08 | 2017-06-09 | 思芬构技术有限公司 | 用于预测对象患糖尿病和/或代谢综合征的风险的方法 |
| PL2846836T3 (pl) * | 2012-05-07 | 2020-01-31 | Allergan, Inc. | Sposób leczenia amd u pacjentów opornych na terapię anty- vegf |
| KR102288287B1 (ko) | 2012-06-01 | 2021-08-11 | 노파르티스 아게 | 시린지 |
| KR20150023957A (ko) * | 2012-06-28 | 2015-03-05 | 몰리큘라 파트너스 아게 | 혈소판-유래 성장인자에 결합하는 설계된 안키린 반복 단백질 |
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| JP2015528454A (ja) * | 2012-08-28 | 2015-09-28 | ノバルティス アーゲー | 眼血管増殖性疾患の処置におけるｖｅｇｆアンタゴニストの使用 |
| TR201809001T4 (tr) | 2012-10-02 | 2018-07-23 | Sphingotec Gmbh | Böbrek fonksiyonunu teşhis etmek veya izlemek veya böbrek fonksiyonu bozukluğunu teşhis etmek için bir usul. |
| EP2738180A1 (en) | 2012-11-30 | 2014-06-04 | Molecular Partners AG | Binding proteins comprising at least two binding domains against HER2. |
| EP2943795B1 (en) | 2013-01-08 | 2021-02-24 | sphingotec GmbH | Fasting levels of growth hormone as a predictive marker of cardiovascular risk |
| KR20150122761A (ko) * | 2013-02-26 | 2015-11-02 | 로슈 글리카트 아게 | Ｔ 세포 활성화 항원 결합 분자 |
| CA2902547A1 (en) * | 2013-03-14 | 2014-09-25 | Allergan, Inc. | Composition of a sustained-release delivery and method of stabilizing proteins during fabrication process |
| SG10201800309SA (en) | 2013-03-20 | 2018-02-27 | Sphingotec Gmbh | Adrenomedullin to guide therapy of blood pressure decline |
| FR3004650B1 (fr) * | 2013-04-22 | 2015-05-29 | Affilogic | Composition topique comprenant un variant d'une protéine sauvage à pli-OB, ainsi que son procédé de préparation |
| EP3004152B1 (en) | 2013-05-31 | 2020-09-30 | Molecular Partners AG | Designed ankyrin repeat proteins binding to hepatocyte growth factor |
| US20160129080A1 (en) | 2013-06-20 | 2016-05-12 | Aaron Osborne | Treatment of polypoidal chroidal vasculopathy |
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| MX2016000384A (es) | 2013-07-11 | 2016-04-29 | Novartis Ag | Uso de un antagonista de vegf en el tratamiento de trastornos coriorretinianos neovasculares y de permeabilidad en pacientes pediatricos. |
| BR112016000282A2 (pt) | 2013-07-11 | 2017-12-12 | Novartis Ag | uso de antagonista de vegf em tratamento de retinopatia da prematuridade |
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| CN105960247A (zh) | 2013-11-05 | 2016-09-21 | 阿勒根公司 | 用抗vegf darpin治疗眼病的方法 |
| EP3828202A1 (en) | 2014-05-12 | 2021-06-02 | Formycon AG | Pre-filled plastic syringe containing a vegf antagonist |
| EP3002589A1 (en) | 2014-10-01 | 2016-04-06 | sphingotec GmbH | A method for stratifying a female subject for hormone replacement therapy |
| IL276944B (en) * | 2015-04-02 | 2022-07-01 | Molecular Partners Ag | Designed ankyrin repeat domains with binding specificity for serum albumin |
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| TWI799366B (zh) | 2015-09-15 | 2023-04-21 | 美商建南德克公司 | 胱胺酸結骨架平臺 |
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