BRPI0920041A2 - composições e processos relacionados às proteínas eap, emp e/ou adsa bacterianas - Google Patents
composições e processos relacionados às proteínas eap, emp e/ou adsa bacterianasInfo
- Publication number
- BRPI0920041A2 BRPI0920041A2 BRPI0920041A BRPI0920041A BRPI0920041A2 BR PI0920041 A2 BRPI0920041 A2 BR PI0920041A2 BR PI0920041 A BRPI0920041 A BR PI0920041A BR PI0920041 A BRPI0920041 A BR PI0920041A BR PI0920041 A2 BRPI0920041 A2 BR PI0920041A2
- Authority
- BR
- Brazil
- Prior art keywords
- adsa
- emp
- eap
- bacterial
- processes
- Prior art date
Links
- 230000001580 bacterial effect Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
- C07K16/1271—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Micrococcaceae (F), e.g. Staphylococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/085—Staphylococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
- C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
- C07K16/1278—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Bacillus (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A61K2039/507—Comprising a combination of two or more separate antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/55—Fusion polypeptide containing a fusion with a toxin, e.g. diphteria toxin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Mycology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10319608P | 2008-10-06 | 2008-10-06 | |
US10319008P | 2008-10-06 | 2008-10-06 | |
US17077909P | 2009-04-20 | 2009-04-20 | |
PCT/US2009/059648 WO2010042481A1 (en) | 2008-10-06 | 2009-10-06 | Compositions and methods related to bacterial eap, emp, and/or adsa proteins |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0920041A2 true BRPI0920041A2 (pt) | 2017-06-27 |
Family
ID=41382468
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0920041A BRPI0920041A2 (pt) | 2008-10-06 | 2009-10-06 | composições e processos relacionados às proteínas eap, emp e/ou adsa bacterianas |
Country Status (8)
Country | Link |
---|---|
US (1) | US20110262477A1 (ja) |
EP (1) | EP2341929B1 (ja) |
JP (1) | JP2012504660A (ja) |
CN (1) | CN102333540B (ja) |
AU (1) | AU2009302582A1 (ja) |
BR (1) | BRPI0920041A2 (ja) |
CA (1) | CA2739581A1 (ja) |
WO (1) | WO2010042481A1 (ja) |
Families Citing this family (28)
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US20180221466A9 (en) * | 2006-06-12 | 2018-08-09 | Glaxosmithkline Biologicals S.A. | Use of alpha-toxin for treating and preventing staphylococcus infections |
EP2666784B1 (en) * | 2007-08-31 | 2017-04-05 | University Of Chicago | Methods and compositions related to immunizing against staphylococcal lung diseases and conditions |
US9181329B2 (en) | 2007-08-31 | 2015-11-10 | The University Of Chicago | Methods and compositions related to immunizing against Staphylococcal lung diseases and conditions |
PL2493498T3 (pl) | 2009-10-30 | 2017-08-31 | Glaxosmithkline Biologicals Sa | Oczyszczanie sacharydów otoczkowych staphylococcus aureus typu 5 i typu 8 |
CN101914144B (zh) * | 2010-04-30 | 2013-01-09 | 浙江大学 | 金黄色葡萄球菌荚膜多糖和蛋白质偶联物及制备方法和用途 |
ES2655701T3 (es) | 2010-07-02 | 2018-02-21 | The University Of Chicago | Composiciones y métodos relacionados con variantes de la proteína A (SpA) |
JP5793194B2 (ja) * | 2010-09-09 | 2015-10-14 | ザ・ユニバーシティ・オブ・シカゴThe University Of Chicago | 感染防御ブドウ球菌抗原が関与する方法および組成物 |
CA2845259A1 (en) | 2011-08-15 | 2013-02-21 | The University Of Chicago | Compositions and methods related to antibodies to staphylococcal protein a |
CA2910320A1 (en) | 2012-04-26 | 2013-10-31 | University Of Chicago | Compositions and methods related to antibodies that neutralize coagulase activity during staphylococcus aureus disease |
ES2806945T3 (es) * | 2012-04-26 | 2021-02-19 | Univ Chicago | Antígenos de coagulasa estafilocócica y métodos para su uso |
CN102993308B (zh) * | 2012-09-29 | 2014-11-05 | 重庆原伦生物科技有限公司 | 耐甲氧西林金黄色葡萄球菌(mrsa)疫苗重组蛋白抗原hi2及制备方法和应用 |
WO2014074540A2 (en) | 2012-11-06 | 2014-05-15 | Medimmune, Llc | Antibodies to s. aureus surface determinants |
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KR20160015227A (ko) | 2013-05-31 | 2016-02-12 | 제넨테크, 인크. | 항-세포벽 테이코산 항체 및 접합체 |
KR20160015286A (ko) | 2013-05-31 | 2016-02-12 | 제넨테크, 인크. | 항-세포벽 테이코산 항체 및 접합체 |
SG11201607070VA (en) | 2014-05-02 | 2016-11-29 | Momenta Pharmaceuticals Inc | Compositions and methods related to engineered fc constructs |
MX2017007231A (es) | 2014-12-03 | 2017-11-08 | Genentech Inc | Conjugados de rifamicina y anticuerpos contra el staphylococcuss aureus y usos de estos. |
BR112017011325A2 (pt) | 2014-12-03 | 2020-07-21 | Genentech, Inc. | ?composto de conjugado anticorpo?antibiótico, composição, método de tratamento de uma infecção, método para matar staph aureus, processo para produzir o conjugado, kit para o tratamento de uma infecção, intermediários antibiótico-ligante e ligante-droga? |
WO2016095832A1 (en) * | 2014-12-18 | 2016-06-23 | The University Of Hong Kong | Immunotherapeutic targets against staphylococcus aureus |
CN105424930A (zh) * | 2015-11-23 | 2016-03-23 | 天津科技大学 | 一种快速检测金黄色葡萄球菌的方法 |
EP3423572B1 (en) * | 2016-03-02 | 2023-11-29 | Momenta Pharmaceuticals, Inc. | Methods related to engineered fc constructs |
CN109963869A (zh) | 2016-05-23 | 2019-07-02 | 动量制药公司 | 与经改造的Fc构建体相关的组合物和方法 |
WO2018083476A1 (en) * | 2016-11-03 | 2018-05-11 | Oxford University Innovation Limited | Fusion polypeptides derived from staphylococcus aureus antigens |
BR112019013955A2 (pt) | 2017-01-06 | 2020-02-11 | Momenta Pharmaceuticals, Inc. | Composições e métodos relacionados a construtos de fc manipulados |
US11179454B2 (en) * | 2017-03-15 | 2021-11-23 | London School Of Hygiene And Tropical Medicine | Whole cell vaccines |
US11041217B2 (en) * | 2018-01-05 | 2021-06-22 | Azitra Inc | Auxotrophic strains of staphylococcus bacterium |
WO2021233420A1 (en) * | 2020-05-22 | 2021-11-25 | Versitech Limited | A live strain of staphylococcus aureus and uses thereof |
CN116472342A (zh) * | 2020-05-22 | 2023-07-21 | 港大科桥有限公司 | 一种金黄色葡萄球菌的活菌株及其用途 |
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SE0000514D0 (sv) | 2000-02-17 | 2000-02-17 | Biostapro Ab | A 52 kDa protein from coagulase negative staphylococci and fragments |
JP4164361B2 (ja) | 2000-11-07 | 2008-10-15 | イムノワクチン テクノロジーズ インコーポレーテッド | 増強した免疫応答を有するワクチン、およびその調製方法 |
AT410798B (de) * | 2001-01-26 | 2003-07-25 | Cistem Biotechnologies Gmbh | Verfahren zur identifizierung, isolierung und herstellung von antigenen gegen ein spezifisches pathogen |
WO2002074324A1 (en) | 2001-03-15 | 2002-09-26 | The Texas A & M University System | Collagen-binding adhesin from staphylococcus epidermidis and method of use |
GB0107661D0 (en) * | 2001-03-27 | 2001-05-16 | Chiron Spa | Staphylococcus aureus |
US7115264B2 (en) | 2001-11-05 | 2006-10-03 | Inhibitex | Monoclonal antibodies to the fibronectin binding protein and method of use in treating or preventing infections |
CA2469132A1 (en) | 2001-12-11 | 2003-07-03 | Merck & Co., Inc. | Staphylococcus aureus exopolysaccharide and process |
EP1565478B1 (en) | 2002-11-12 | 2017-08-02 | The Brigham And Women's Hospital, Inc. | Polysaccharide vaccine for staphylococcal infections |
EP1583517B1 (en) | 2002-11-12 | 2019-06-12 | The Brigham And Women's Hospital, Inc. | Methods and products for treating staphylococcal infections |
EP1791560A4 (en) * | 2004-09-17 | 2009-01-14 | Merck & Co Inc | POLYPEPTIDES FOR INDUCING AN IMMUNE RESPONSE OF PROTECTION DIRECTED AGAINST STAPHYLOCOCCUS AUREUS |
US8758765B2 (en) * | 2008-07-29 | 2014-06-24 | The University Of Chicago | Compositions and methods related to Staphylococcal bacterium proteins |
FR2957821B1 (fr) | 2010-03-24 | 2014-08-29 | Inst Francais Du Petrole | Nouvelle zone de regeneration du catalyseur divisee en secteurs pour unites catalytiques regeneratives |
-
2009
- 2009-10-06 CN CN200980146554.XA patent/CN102333540B/zh not_active Expired - Fee Related
- 2009-10-06 WO PCT/US2009/059648 patent/WO2010042481A1/en active Application Filing
- 2009-10-06 US US13/122,793 patent/US20110262477A1/en not_active Abandoned
- 2009-10-06 AU AU2009302582A patent/AU2009302582A1/en not_active Abandoned
- 2009-10-06 EP EP09793315.4A patent/EP2341929B1/en not_active Not-in-force
- 2009-10-06 JP JP2011530297A patent/JP2012504660A/ja active Pending
- 2009-10-06 CA CA2739581A patent/CA2739581A1/en not_active Abandoned
- 2009-10-06 BR BRPI0920041A patent/BRPI0920041A2/pt not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US20110262477A1 (en) | 2011-10-27 |
JP2012504660A (ja) | 2012-02-23 |
WO2010042481A1 (en) | 2010-04-15 |
CN102333540B (zh) | 2015-04-22 |
CA2739581A1 (en) | 2010-04-15 |
EP2341929B1 (en) | 2017-01-25 |
EP2341929A1 (en) | 2011-07-13 |
CN102333540A (zh) | 2012-01-25 |
AU2009302582A1 (en) | 2010-04-15 |
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