BRPI0918936A2 - conversão de derivados de prenila em isopreno - Google Patents
conversão de derivados de prenila em isoprenoInfo
- Publication number
- BRPI0918936A2 BRPI0918936A2 BRPI0918936A BRPI0918936A BRPI0918936A2 BR PI0918936 A2 BRPI0918936 A2 BR PI0918936A2 BR PI0918936 A BRPI0918936 A BR PI0918936A BR PI0918936 A BRPI0918936 A BR PI0918936A BR PI0918936 A2 BRPI0918936 A2 BR PI0918936A2
- Authority
- BR
- Brazil
- Prior art keywords
- isoprene
- conversion
- prenyl derivatives
- prenyl
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
- C12P5/007—Preparation of hydrocarbons or halogenated hydrocarbons containing one or more isoprene units, i.e. terpenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C1/00—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon
- C07C1/20—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon starting from organic compounds containing only oxygen atoms as heteroatoms
- C07C1/207—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon starting from organic compounds containing only oxygen atoms as heteroatoms from carbonyl compounds
- C07C1/2078—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon starting from organic compounds containing only oxygen atoms as heteroatoms from carbonyl compounds by a transformation in which at least one -C(=O)-O- moiety is eliminated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C1/00—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon
- C07C1/20—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon starting from organic compounds containing only oxygen atoms as heteroatoms
- C07C1/24—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon starting from organic compounds containing only oxygen atoms as heteroatoms by elimination of water
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/90—Isomerases (5.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/03—Phosphoric monoester hydrolases (3.1.3)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/07—Diphosphoric monoester hydrolases (3.1.7)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y306/00—Hydrolases acting on acid anhydrides (3.6)
- C12Y306/01—Hydrolases acting on acid anhydrides (3.6) in phosphorus-containing anhydrides (3.6.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y503/00—Intramolecular oxidoreductases (5.3)
- C12Y503/03—Intramolecular oxidoreductases (5.3) transposing C=C bonds (5.3.3)
- C12Y503/03002—Isopentenyl-diphosphate DELTA-isomerase (5.3.3.2)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9720408P | 2008-09-15 | 2008-09-15 | |
PCT/US2009/057036 WO2010031076A2 (en) | 2008-09-15 | 2009-09-15 | Conversion of prenyl derivatives to isoprene |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0918936A2 true BRPI0918936A2 (pt) | 2019-09-24 |
Family
ID=42005829
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0918936A BRPI0918936A2 (pt) | 2008-09-15 | 2009-09-15 | conversão de derivados de prenila em isopreno |
Country Status (7)
Country | Link |
---|---|
US (3) | US8476049B2 (pt) |
EP (1) | EP2340312A2 (pt) |
BR (1) | BRPI0918936A2 (pt) |
CA (1) | CA2737195A1 (pt) |
SG (1) | SG169614A1 (pt) |
WO (1) | WO2010031076A2 (pt) |
ZA (1) | ZA201102109B (pt) |
Families Citing this family (55)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20100118973A (ko) | 2007-12-13 | 2010-11-08 | 다니스코 유에스 인크. | 이소프렌을 생성하기 위한 조성물 및 방법 |
US8173410B2 (en) * | 2008-04-23 | 2012-05-08 | Danisco Us Inc. | Isoprene synthase variants for improved microbial production of isoprene |
KR20110038087A (ko) | 2008-06-30 | 2011-04-13 | 더 굿이어 타이어 앤드 러버 캄파니 | 재생가능 자원으로부터의 이소프렌 중합체 |
SG169614A1 (en) | 2008-09-15 | 2011-04-29 | Goodyear Tire & Rubber | Conversion of prenyl derivatives to isoprene |
SG169652A1 (en) * | 2008-09-15 | 2011-04-29 | Danisco Us Inc | Reduction of carbon dioxide emission during isoprene production by fermentation |
CN102333866B (zh) * | 2008-12-30 | 2015-04-29 | 丹尼斯科美国公司 | 生产异戊二烯和共同产物的方法 |
US8324442B2 (en) | 2009-03-03 | 2012-12-04 | Amyris, Inc. | Microbial derived isoprene and methods for making the same |
CA2759700A1 (en) | 2009-04-23 | 2010-10-28 | Danisco Us Inc. | Three-dimensional structure of isoprene synthase and its use thereof for generating variants |
TW201120213A (en) | 2009-06-17 | 2011-06-16 | Danisco Us Inc | Polymerization of isoprene from renewable resources |
TWI434921B (zh) | 2009-06-17 | 2014-04-21 | Danisco Us Inc | 從生物異戊二烯組合物製造燃料成分之方法及系統 |
TW201412988A (zh) | 2009-06-17 | 2014-04-01 | Danisco Us Inc | 使用dxp及mva途徑之改良之異戊二烯製造 |
US20110039323A1 (en) * | 2009-08-14 | 2011-02-17 | Eric Lawrence Singsaas | Isoprene Production |
IN2012DN05187A (pt) | 2009-12-18 | 2015-10-23 | Danisco Us Inc | |
SG196782A1 (en) | 2009-12-23 | 2014-02-13 | Danisco Us Inc | Compositions and methods for the increased production of isoprene and other products with 6 - phosphogluconolactonase (pgl) |
BR112012032276A2 (pt) | 2010-06-17 | 2016-11-16 | Danisco Us Inc | composições de combustível compreendendo derivados de isopreno |
EP2601300A1 (en) | 2010-08-06 | 2013-06-12 | Danisco US Inc. | Production of isoprene under neutral ph conditions |
WO2012058494A2 (en) | 2010-10-27 | 2012-05-03 | Danisco Us Inc. | Isoprene synthase variants for improved production of isoprene |
JP2014502844A (ja) | 2010-12-22 | 2014-02-06 | ダニスコ・ユーエス・インク | 組み換え細胞による五炭糖の生物学的生産 |
BR112013018316A2 (pt) | 2010-12-22 | 2018-09-11 | Danisco Us Inc | composições e métodos para produção aprimorada de isopreno usando dois tipos de enzimas ispg |
EP2702139A1 (en) | 2011-04-29 | 2014-03-05 | Danisco US Inc. | Production of mevalonate, isoprene, and isoprenoids using genes encoding polypeptides having thiolase, hmg-coa synthase and hmg-coa reductase enzymatic activities |
WO2012149491A2 (en) | 2011-04-29 | 2012-11-01 | Danisco Us Inc. | Recombinant microorganisms for enhanced production of mevalonate, isoprene, and isoprenoids |
US20130122562A1 (en) | 2011-08-04 | 2013-05-16 | Danisco Us Inc. | Production of isoprene, isoprenoid precursors, and isoprenoids using acetoacetyl-coa synthase |
US8951764B2 (en) | 2011-08-05 | 2015-02-10 | Danisco Us Inc. | Production of isoprenoids under neutral pH conditions |
EP2764084B2 (en) | 2011-10-07 | 2021-11-03 | Danisco US Inc. | Utilization of phosphoketolase in the production of mevalonate, isoprenoid precursors, and isoprene |
WO2013053824A1 (en) | 2011-10-11 | 2013-04-18 | Metabolic Explorer | New biosynthesis pathway for prenol in a recombinant microorganism |
US8735134B2 (en) | 2011-10-27 | 2014-05-27 | Danisco Us Inc. | Isoprene synthase variants with improved solubility for production of isoprene |
AU2012358149A1 (en) | 2011-12-23 | 2014-07-03 | Danisco Us Inc. | Enhanced production of isoprene using host cells having decreased ispA activity |
WO2013096917A1 (en) | 2011-12-23 | 2013-06-27 | Danisco Us Inc. | Production of isoprene under reduced oxygen inlet levels |
US9315831B2 (en) | 2012-03-30 | 2016-04-19 | Danisco Us Inc. | Direct starch to fermentable sugar as feedstock for the production of isoprene, isoprenoid precursor molecules, and/or isoprenoids |
US20130295627A1 (en) * | 2012-04-09 | 2013-11-07 | Robert J. Hanchar | Process for producing methyl butenol (2-methyl-3-buten-2-ol) |
US8895277B2 (en) | 2012-05-02 | 2014-11-25 | Danisco Us Inc. | Legume isoprene synthase for production of isoprene |
US9163263B2 (en) | 2012-05-02 | 2015-10-20 | The Goodyear Tire & Rubber Company | Identification of isoprene synthase variants with improved properties for the production of isoprene |
KR20150014941A (ko) | 2012-05-16 | 2015-02-09 | 글리코스 바이오테크놀로지스, 인코포레이티드 | 아이소프렌의 생산을 위한 미생물유기체 및 방법 |
WO2013181647A2 (en) | 2012-06-01 | 2013-12-05 | Danisco Us Inc. | Compositions and methods of producing isoprene and/or industrrial bio-products using anaerobic microorganisms |
EP2935364A2 (en) | 2012-12-21 | 2015-10-28 | Danisco US Inc. | Production of isoprene, isoprenoid, and isoprenoid precursors using an alternative lower mevalonate pathway |
US9850512B2 (en) | 2013-03-15 | 2017-12-26 | The Research Foundation For The State University Of New York | Hydrolysis of cellulosic fines in primary clarified sludge of paper mills and the addition of a surfactant to increase the yield |
EP2984105B1 (en) | 2013-04-10 | 2019-05-22 | Danisco US Inc. | Phosphoketolases for improved production of acetyl coenzyme a-derived metabolites, isoprene, isoprenoid precursors, and isoprenoids |
ES2728307T3 (es) | 2013-06-21 | 2019-10-23 | Danisco Us Inc | Composiciones y métodos para la transformación clostridial |
EP3075843B1 (en) | 2013-11-28 | 2019-07-03 | Ajinomoto Co., Inc. | Method for producing isoprene monomer |
JP6744819B2 (ja) | 2014-02-20 | 2020-08-19 | ダニスコ・ユーエス・インク | メバロン酸、イソプレン、イソプレノイド前駆体、イソプレノイド、およびアセチルCoA由来産物の生産向上のための組換え微生物 |
US9951363B2 (en) | 2014-03-14 | 2018-04-24 | The Research Foundation for the State University of New York College of Environmental Science and Forestry | Enzymatic hydrolysis of old corrugated cardboard (OCC) fines from recycled linerboard mill waste rejects |
WO2016015021A1 (en) | 2014-07-24 | 2016-01-28 | The Regents Of The University Of California | Oxidative starch degradation by a new family of pmos |
US10113186B2 (en) | 2014-11-13 | 2018-10-30 | Global Bioenergies | Alkenol dehydratase variants |
WO2016085987A1 (en) * | 2014-11-26 | 2016-06-02 | Visolis, Inc. | Processes for conversion of biologically derived mevalonic acid |
CN104910448B (zh) * | 2015-06-03 | 2017-06-06 | 华南理工大学 | 一种医用套扎器环形弹性圈的制备方法 |
US20180237359A1 (en) * | 2015-08-19 | 2018-08-23 | Technology Holding, Llc | Hybrid chem-bio method to produce diene molecules |
RU2734778C2 (ru) * | 2016-05-06 | 2020-10-23 | Курарей Ко., Лтд. | Способ получения сопряженного диена |
US20190241913A1 (en) * | 2016-10-12 | 2019-08-08 | Reliance Industries Limited | Method for production of isoprene recombinant microorganism, gene construct, vector and application thereof |
CA3062645A1 (en) | 2017-05-10 | 2018-11-15 | Baymedica, Inc. | Recombinant production systems for prenylated polyketides of the cannabinoid family |
CA3084263A1 (en) | 2017-12-07 | 2019-06-13 | Zymergen Inc. | Engineered biosynthetic pathways for production of (6e)-8-hydroxygeraniol by fermentation |
CN111868047A (zh) | 2017-12-21 | 2020-10-30 | 齐默尔根公司 | 荆芥内半缩醛氧化还原酶、荆芥内半缩醛合酶和能够产生荆芥内酯的微生物 |
EP3861109A1 (en) | 2018-10-05 | 2021-08-11 | Ajinomoto Co., Inc. | Method for producing target substance by bacterial fermentation |
CN110241103B (zh) * | 2019-07-04 | 2021-01-19 | 江西邦泰绿色生物合成生态产业园发展有限公司 | 一种生物酶法生产异戊二烯的方法 |
EP4347800A1 (en) | 2021-05-26 | 2024-04-10 | Invizyne Technologies, Inc. | Prenyltransferase variants with increased thermostability |
WO2023077017A1 (en) * | 2021-10-27 | 2023-05-04 | The Regents Of The University Of California | Methods and compositions useful for the production of olefinic ester |
Family Cites Families (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3792104A (en) * | 1970-06-27 | 1974-02-12 | Basf Ag | Manufacture of isoprene |
JPS5242763B2 (pt) * | 1971-01-12 | 1977-10-26 | ||
CA1338400C (en) | 1983-08-31 | 1996-06-18 | David H. Gelfand | Recombinant fungal cellulases |
GB8407828D0 (en) * | 1984-03-27 | 1984-05-02 | Ontario Research Foundation | In situ preparation |
US4570029A (en) * | 1985-03-04 | 1986-02-11 | Uop Inc. | Process for separating isoprene |
US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
EP0215594B2 (en) | 1985-08-29 | 2003-10-15 | Genencor International, Inc. | Heterologous polypeptide expressed in filamentous fungi, processes for their preparation, and vectors for their preparation |
DK122686D0 (da) | 1986-03-17 | 1986-03-17 | Novo Industri As | Fremstilling af proteiner |
GB8610600D0 (en) | 1986-04-30 | 1986-06-04 | Novo Industri As | Transformation of trichoderma |
US4734538A (en) * | 1986-12-24 | 1988-03-29 | Union Carbide Corporation | Process for the production of dienes |
DK1225227T3 (da) * | 1990-12-10 | 2009-06-22 | Genencor Int | Forbedret forsukring af cellulose ved kloning og amplifikation af beta-glucosidase genet af trichoderma |
WO1995004134A1 (en) | 1993-08-02 | 1995-02-09 | Genencor International, Inc. | Method of reducing complex carbohydrates in fermentation products |
US5861271A (en) * | 1993-12-17 | 1999-01-19 | Fowler; Timothy | Cellulase enzymes and systems for their expressions |
US5686276A (en) | 1995-05-12 | 1997-11-11 | E. I. Du Pont De Nemours And Company | Bioconversion of a fermentable carbon source to 1,3-propanediol by a single microorganism |
US5849970A (en) * | 1995-06-23 | 1998-12-15 | The Regents Of The University Of Colorado | Materials and methods for the bacterial production of isoprene |
DE19629568C1 (de) | 1996-07-15 | 1998-01-08 | Fraunhofer Ges Forschung | Verfahren zur Herstellung von Isopren |
US6176176B1 (en) * | 1998-04-30 | 2001-01-23 | Board Of Trustees Operating Michigan State University | Apparatus for treating cellulosic materials |
EP2305825B1 (en) * | 1998-07-06 | 2015-01-14 | DCV Inc. doing business as Bio-Technical Resourses | Method of vitamin production |
EP1947189B1 (en) | 1998-07-06 | 2010-12-01 | DCV Inc. doing business as Bio-Technical Resourses | Method of vitamin production |
US6268328B1 (en) * | 1998-12-18 | 2001-07-31 | Genencor International, Inc. | Variant EGIII-like cellulase compositions |
EP1354956A4 (en) | 2000-12-28 | 2004-10-27 | Toyota Motor Co Ltd | PROCESS FOR PRODUCING PRENYL ALCOHOL |
WO2002053751A1 (fr) * | 2000-12-28 | 2002-07-11 | Kabushiki Kaisha Toyota Chuo Kenkyusho | Polypeptides, polynucleotides, acides nucleiques de recombinaison, produits de recombinaison et procede de production d'alcool prenylique |
JP4430869B2 (ja) * | 2001-04-04 | 2010-03-10 | ジェネンコー・インターナショナル・インク | 宿主細胞の分離した生産及び異化経路 |
DE10201458A1 (de) * | 2001-04-11 | 2002-10-17 | Adelbert Bacher | Intermediate und Enzyme des Mevalonat-unabhängigen Isoprenoidbiosyntheseweg |
EP1499709B1 (en) * | 2002-04-22 | 2012-01-04 | E.I. Du Pont De Nemours And Company | Promoter and plasmid system for genetic engineering |
AU2003287028B2 (en) | 2002-10-04 | 2008-09-04 | E.I. Du Pont De Nemours And Company | Process for the biological production of 1,3-propanediol with high yield |
DK1627049T3 (da) | 2003-05-29 | 2010-05-31 | Genencor Int | Nye Trichoderma-gener |
JP5091484B2 (ja) * | 2003-11-21 | 2012-12-05 | ジェネンコー・インターナショナル・インク | トリコデルマにおける顆粒デンプン加水分解酵素の発現及び顆粒デンプン基質からグルコースシロップを製造する方法 |
CA2652732C (en) * | 2006-05-26 | 2015-04-28 | Amyris Biotechnologies, Inc. | Fuel components, fuel compositions and methods of making and using same |
US7947478B2 (en) | 2006-06-29 | 2011-05-24 | The Regents Of The University Of California | Short chain volatile hydrocarbon production using genetically engineered microalgae, cyanobacteria or bacteria |
WO2009006429A1 (en) * | 2007-06-29 | 2009-01-08 | Regents Of The University Of California | Host cells and methods for producing 3-methyl-2-buten-1-ol, 3-methyl-3-buten-1-ol, and 3-methyl-butan-1-ol |
CN102791848B (zh) * | 2008-07-02 | 2017-11-10 | 丹尼斯科美国公司 | 用于在去偶联条件和/或安全操作范围下产生不含c5烃的异戊二烯的方法和组合物 |
SG169614A1 (en) | 2008-09-15 | 2011-04-29 | Goodyear Tire & Rubber | Conversion of prenyl derivatives to isoprene |
-
2009
- 2009-09-15 SG SG201101746A patent/SG169614A1/en unknown
- 2009-09-15 BR BRPI0918936A patent/BRPI0918936A2/pt not_active IP Right Cessation
- 2009-09-15 ZA ZA2011/02109A patent/ZA201102109B/en unknown
- 2009-09-15 EP EP09744251A patent/EP2340312A2/en not_active Withdrawn
- 2009-09-15 US US12/560,370 patent/US8476049B2/en not_active Expired - Fee Related
- 2009-09-15 WO PCT/US2009/057036 patent/WO2010031076A2/en active Application Filing
- 2009-09-15 CA CA2737195A patent/CA2737195A1/en not_active Abandoned
-
2013
- 2013-06-06 US US13/912,002 patent/US8945893B2/en not_active Expired - Fee Related
-
2015
- 2015-01-06 US US14/590,882 patent/US20150191746A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP2340312A2 (en) | 2011-07-06 |
US20130309743A1 (en) | 2013-11-21 |
CA2737195A1 (en) | 2010-03-18 |
US8476049B2 (en) | 2013-07-02 |
US8945893B2 (en) | 2015-02-03 |
SG169614A1 (en) | 2011-04-29 |
ZA201102109B (en) | 2013-10-30 |
WO2010031076A3 (en) | 2010-11-11 |
US20150191746A1 (en) | 2015-07-09 |
WO2010031076A2 (en) | 2010-03-18 |
US20100113846A1 (en) | 2010-05-06 |
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