BRPI0917648A2 - composição e vetor para uso na prevenção ou no tratamento de alergia à erva de santiago por tolerização, produto contendo entre três e treze polipeptídeos, formulação farmacêutica, e, método in vitro. - Google Patents

composição e vetor para uso na prevenção ou no tratamento de alergia à erva de santiago por tolerização, produto contendo entre três e treze polipeptídeos, formulação farmacêutica, e, método in vitro.

Info

Publication number
BRPI0917648A2
BRPI0917648A2 BRPI0917648A BRPI0917648A BRPI0917648A2 BR PI0917648 A2 BRPI0917648 A2 BR PI0917648A2 BR PI0917648 A BRPI0917648 A BR PI0917648A BR PI0917648 A BRPI0917648 A BR PI0917648A BR PI0917648 A2 BRPI0917648 A2 BR PI0917648A2
Authority
BR
Brazil
Prior art keywords
allergy
toleration
vector
prevention
treatment
Prior art date
Application number
BRPI0917648A
Other languages
English (en)
Inventor
Mark Larche
Paul Laidler
Roderick Peter Hafner
Original Assignee
Circassia Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41090318&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0917648(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB0814986A external-priority patent/GB0814986D0/en
Priority claimed from PCT/GB2008/002779 external-priority patent/WO2009022155A2/en
Priority claimed from GB0815218A external-priority patent/GB0815218D0/en
Application filed by Circassia Ltd filed Critical Circassia Ltd
Publication of BRPI0917648A2 publication Critical patent/BRPI0917648A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens
    • A61K39/36—Allergens from pollen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/08—RNA viruses
    • C07K14/145—Rhabdoviridae, e.g. rabies virus, Duvenhage virus, Mokola virus or vesicular stomatitis virus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047—Cells of the immune system
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047—Cells of the immune system
    • G01N33/505—Cells of the immune system involving T-cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5094—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for blood cell populations
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56972—White blood cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/24—Immunology or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Virology (AREA)
  • Mycology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Botany (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
BRPI0917648A 2008-08-15 2009-08-14 composição e vetor para uso na prevenção ou no tratamento de alergia à erva de santiago por tolerização, produto contendo entre três e treze polipeptídeos, formulação farmacêutica, e, método in vitro. BRPI0917648A2 (pt)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB0814986A GB0814986D0 (en) 2008-08-15 2008-08-15 Peptide for il10 production
PCT/GB2008/002779 WO2009022155A2 (en) 2007-08-15 2008-08-15 Peptide with reduced dimer formation
PCT/GB2008/002781 WO2009022157A2 (en) 2007-08-15 2008-08-15 Peptide with improved solubility
GB0815218A GB0815218D0 (en) 2008-08-20 2008-08-20 Ragweed peptides for vaccine
EP09251252.4A EP2153841B2 (en) 2008-08-15 2009-05-01 Vaccine comprising Amb a 1 peptides for use in the treatment of ragweed allergy
PCT/GB2009/001986 WO2010018378A2 (en) 2008-08-15 2009-08-14 Ragweed peptides for vaccine

Publications (1)

Publication Number Publication Date
BRPI0917648A2 true BRPI0917648A2 (pt) 2015-12-01

Family

ID=41090318

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0917648A BRPI0917648A2 (pt) 2008-08-15 2009-08-14 composição e vetor para uso na prevenção ou no tratamento de alergia à erva de santiago por tolerização, produto contendo entre três e treze polipeptídeos, formulação farmacêutica, e, método in vitro.

Country Status (18)

Country Link
US (3) US8491910B2 (pt)
EP (3) EP2153841B2 (pt)
JP (1) JP5788319B2 (pt)
KR (1) KR20110044787A (pt)
CN (2) CN104710512A (pt)
AT (1) ATE536880T1 (pt)
AU (1) AU2009281013B2 (pt)
BR (1) BRPI0917648A2 (pt)
CA (1) CA2734379A1 (pt)
DK (1) DK2153841T4 (pt)
EA (1) EA201170336A1 (pt)
ES (1) ES2378870T5 (pt)
HR (1) HRP20120206T4 (pt)
MX (1) MX2011001619A (pt)
PL (1) PL2153841T5 (pt)
PT (1) PT2153841E (pt)
SI (1) SI2153841T2 (pt)
WO (1) WO2010018378A2 (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1958645A1 (en) * 2007-02-13 2008-08-20 Biomay AG Peptides derived from the major allergen of ragweed (Ambrosia artemisiifolia) and uses thereof
ES2378870T5 (es) * 2008-08-15 2016-02-03 Circassia Limited Vacuna que comprende péptidos Amb a 1 para uso en el tratamiento de alergia a ambrosía
WO2010018384A1 (en) * 2008-08-15 2010-02-18 Circassia Limited T-cell antigen peptide from allergen for stimulation of il-10 production
EP3170510A1 (de) 2010-01-14 2017-05-24 Merck Patent GmbH Varianten der gruppe 5-allergene der süssgräser mit reduzierter allergenität durch mutagenese von prolinresten
FI20115374A0 (fi) 2011-04-18 2011-04-18 Teknologian Tutkimuskeskus Vtt Oy Uudet hypoallergeenit
DK2723373T3 (en) * 2011-06-27 2017-09-18 Anergis S A OVERLAPPING ADJUSTING PEPTIDES FOR TREATMENT
ES2623050T3 (es) * 2012-04-16 2017-07-10 Alk-Abelló A/S Polipéptidos profilinas vegetales para su uso en inmunoterapia de alergia inespecífica
DK2914286T3 (da) 2012-10-30 2021-11-08 Aravax Pty Ltd Hidtil ukendte immunterapeutiske molekyler og anvendelser deraf
DK2968528T3 (da) * 2013-03-15 2022-03-28 Sementis Ltd Immunmodulation
EP3049098A4 (en) 2013-09-25 2017-08-16 Aravax Pty Ltd Novel immunotherapeutic composition and uses thereof
WO2017179025A1 (en) 2016-04-15 2017-10-19 Alk-Abelló A/S Epitope polypeptides of ragweed pollen allergens
EP3295956A1 (en) 2016-09-20 2018-03-21 Biomay Ag Polypeptide construct comprising fragments of allergens
CN117362453B (zh) * 2023-12-08 2024-02-27 山东硕景生物科技有限公司 一种Derf1重组抗原、其制备方法及应用

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5776761A (en) * 1989-03-17 1998-07-07 Immulogic Pharmaceutical Corporation Nucleic acids encoding allergenic proteins from ragweed
CA2049921C (en) 1989-03-17 2004-06-15 Bruce Rogers Allergenic proteins from ragweed and uses therefor
US5703055A (en) 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
US5399346A (en) 1989-06-14 1995-03-21 The United States Of America As Represented By The Department Of Health And Human Services Gene therapy
WO1994001560A1 (en) 1991-07-12 1994-01-20 Immulogic Pharmaceutical Corporation Allergenic proteins and peptides from japanese cedar pollen
EP0636180A1 (en) 1992-04-09 1995-02-01 Immulogic Pharmaceutical Corporation T CELL EPITOPES OF THE MAJOR ALLERGENS FROM $i(AMBROSIA ARTEMISIIFOLIA)
JPH07257419A (ja) 1994-03-24 1995-10-09 Kubota Corp 農作業車
US5968526A (en) 1994-04-14 1999-10-19 Immulogic Pharamaceutical Corporation T cell epitopes of the major allergens from Dermatophagoides (house dust mite)
AU4146796A (en) * 1994-10-27 1996-05-23 Immulogic Pharmaceutical Corporation T cell epitopes of the major allergens from ambrosia artemisiifolia
IL115744A (en) 1994-10-27 2000-07-16 Akzo Nobel Nv Peptides comprising a subsequence of human cartilage glycoprotein - 39
EP1044019A1 (en) 1998-01-09 2000-10-18 Circassia Limited Methods and compositions for desensitisation
US6989146B2 (en) 2000-08-09 2006-01-24 The Regents Of The University Of California Stress proteins and peptides and methods of use thereof
ATE414534T1 (de) 2001-12-05 2008-12-15 Circassia Ltd Immunotherapeutische methoden und systeme
AU2003228133A1 (en) 2002-04-22 2003-11-03 Umc Utrecht Holding B.V. Reduction of unwanted immune reactions
GB0210741D0 (en) 2002-05-10 2002-06-19 Medical Res Council Methods of therapy
GB0308988D0 (en) 2003-04-17 2003-05-28 Univ Singapore Molecule
WO2006075253A2 (en) 2005-01-11 2006-07-20 Commissariat A L'energie Atomique Peptides for desensitizing subjects allergic to dog hair and dander and compositions containing said peptides.
CN101171033A (zh) * 2005-03-04 2008-04-30 戴纳瓦克斯技术公司 包含具免疫刺激序列iss之寡核苷酸的疫苗：其中iss与抗原缀合并通过缓冲条件和其他赋形剂稳定
EP1899367A4 (en) 2005-06-10 2009-06-24 Univ Singapore MUTANT ALLERGENS
US20070092532A1 (en) 2005-10-25 2007-04-26 Board Of Trustees Operating Michigan State University Arthritis vaccines and methods
CN100457180C (zh) * 2005-11-09 2009-02-04 浙江我武生物科技有限公司 用于治疗过敏性疾病的药物组合物及其制备方法
RU2420569C2 (ru) 2005-11-29 2011-06-10 Актогеникс Нв Индукция толерантности к антигенам через слизистую
AT503690A1 (de) * 2006-06-09 2007-12-15 Biomay Ag Hypoallergene moleküle
EP1958645A1 (en) 2007-02-13 2008-08-20 Biomay AG Peptides derived from the major allergen of ragweed (Ambrosia artemisiifolia) and uses thereof
WO2008139163A1 (en) 2007-05-09 2008-11-20 Circassia Limited Prognostic assay for determining t cell response to hla antigens and use thereof in field of tissue transplantation
GB0710529D0 (en) 2007-06-01 2007-07-11 Circassia Ltd Vaccine
WO2009022154A2 (en) 2007-08-15 2009-02-19 Circassia Limited Peptide with multiple epitopes
ES2378870T5 (es) * 2008-08-15 2016-02-03 Circassia Limited Vacuna que comprende péptidos Amb a 1 para uso en el tratamiento de alergia a ambrosía

Also Published As

Publication number Publication date
EA201170336A1 (ru) 2011-10-31
PT2153841E (pt) 2012-03-21
PL2153841T3 (pl) 2012-05-31
WO2010018378A3 (en) 2010-07-22
US20120108524A1 (en) 2012-05-03
EP2444100A2 (en) 2012-04-25
EP2153841B1 (en) 2011-12-14
US20130295123A1 (en) 2013-11-07
CN102170897A (zh) 2011-08-31
WO2010018378A2 (en) 2010-02-18
US8491910B2 (en) 2013-07-23
EP2433639A2 (en) 2012-03-28
KR20110044787A (ko) 2011-04-29
HRP20120206T4 (hr) 2016-02-12
CN104710512A (zh) 2015-06-17
US20170014505A1 (en) 2017-01-19
ES2378870T3 (es) 2012-04-18
MX2011001619A (es) 2011-03-25
CA2734379A1 (en) 2010-02-18
EP2444100A3 (en) 2012-07-25
ATE536880T1 (de) 2011-12-15
US9347937B2 (en) 2016-05-24
CN102170897B (zh) 2015-02-04
DK2153841T4 (en) 2016-02-15
HRP20120206T1 (en) 2012-03-31
ES2378870T5 (es) 2016-02-03
EP2153841A1 (en) 2010-02-17
SI2153841T1 (sl) 2012-04-30
AU2009281013A1 (en) 2010-02-18
DK2153841T3 (da) 2012-03-26
JP5788319B2 (ja) 2015-09-30
EP2433639A3 (en) 2012-06-27
SI2153841T2 (sl) 2016-02-29
PL2153841T5 (pl) 2016-09-30
AU2009281013B2 (en) 2015-01-29
JP2012500193A (ja) 2012-01-05
EP2153841B2 (en) 2015-11-11
WO2010018378A8 (en) 2010-10-28

Similar Documents

Publication Publication Date Title
BRPI0917648A2 (pt) composição e vetor para uso na prevenção ou no tratamento de alergia à erva de santiago por tolerização, produto contendo entre três e treze polipeptídeos, formulação farmacêutica, e, método in vitro.
Vassilopoulou et al. Effect of in vitro gastric and duodenal digestion on the allergenicity of grape lipid transfer protein
Koppelman et al. Allergenicity attributes of different peanut market types
CY1112655T1 (el) Γλυκοζυλιωμενη ιl-7, παρασκευη και χρησεις
MY177052A (en) Anti a beta antibody formulation
BRPI0811320A2 (pt) Surfactantes reconstituídos com propriedades melhoradas
WO2007092772A3 (en) Protein formulations
WO2005082927A3 (en) Antihypertensive peptides
EA019923B1 (ru) Композиции со сниженным образованием димеров
Cabrera-Chávez et al. Maize prolamins resistant to peptic-tryptic digestion maintain immune-recognition by IgA from some celiac disease patients
ES2657414T3 (es) Uso de la lactoferrina en el diagnóstico o el pronóstico de la enfermedad de Alzheimer
Hofer et al. Tackling Bet v 1 and associated food allergies with a single hybrid protein
EA202190310A1 (ru) Белок для лечения воспалительных заболеваний
Gadermaier et al. Isoform identification and characterization of Art v 3, the lipid-transfer protein of mugwort pollen
NO331277B1 (no) Farmasoytisk sammensetning omfattende polypetid/nukleinsyre for behandling av retinale degenererende sykdommer, vektor, isolert polypeptid, renset antistoff og anvendelse av polypeptid, nukleinsyre og antistoff, samt fremgangsmater og kit
Sabato et al. Basophil activation reveals divergent patient-specific responses to thermally processed peanuts
Davies et al. The dominant 55 kDa allergen of the subtropical Bahia grass (Paspalum notatum) pollen is a group 13 pollen allergen, Pas n 13
WO2007134118A3 (en) Protein based composition and methods of using same
IL177698A0 (en) Fusion proeins comprising modified allergens of the ns-ltps family, use thereof and pharmaceutical compositions comprising the same
Marzban et al. Identification of four IgE‐reactive proteins in raspberry (Rubus ideaeus L.)
ATE531384T1 (de) Peptide aus dem plasminogenaktivator-hemmer 1 und ihre verwendung
WO2009103319A3 (en) Ezrin, serpin b5, peroxiredoxin-2 and heat shock protein beta-1 as autoantigens for treating or detecting streptococcal diseases
ATE290081T1 (de) Parietaria judaica ns-ltp-antigenvarianten, entsprechende pharmazeutische zusammensetzungen und ihre verwendung
WO2007052154A3 (en) Erythropoietin-derived short peptide and its mimics as immuno/inflammatory modulators
Sudha et al. Stability of protease-rich Periplaneta americana allergen extract during storage: formulating preservatives to enhance shelf life

Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2475 DE 12-06-2018 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.