ATE414534T1 - Immunotherapeutische methoden und systeme - Google Patents
Immunotherapeutische methoden und systemeInfo
- Publication number
- ATE414534T1 ATE414534T1 AT02783303T AT02783303T ATE414534T1 AT E414534 T1 ATE414534 T1 AT E414534T1 AT 02783303 T AT02783303 T AT 02783303T AT 02783303 T AT02783303 T AT 02783303T AT E414534 T1 ATE414534 T1 AT E414534T1
- Authority
- AT
- Austria
- Prior art keywords
- methods
- polypeptide antigen
- peptides
- antigen
- systems
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 5
- 230000001024 immunotherapeutic effect Effects 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 8
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 8
- 239000000427 antigen Substances 0.000 abstract 6
- 102000036639 antigens Human genes 0.000 abstract 6
- 108091007433 antigens Proteins 0.000 abstract 6
- 229920001184 polypeptide Polymers 0.000 abstract 5
- 230000004046 hyporesponsiveness Effects 0.000 abstract 2
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 1
- 238000011260 co-administration Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/35—Allergens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/35—Allergens
- A61K39/36—Allergens from pollen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Neurology (AREA)
- Endocrinology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Dermatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Emergency Medicine (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Ophthalmology & Optometry (AREA)
- Otolaryngology (AREA)
- Reproductive Health (AREA)
- Obesity (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33838501P | 2001-12-05 | 2001-12-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE414534T1 true ATE414534T1 (de) | 2008-12-15 |
Family
ID=23324613
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02783303T ATE414534T1 (de) | 2001-12-05 | 2002-12-05 | Immunotherapeutische methoden und systeme |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20060024334A1 (de) |
| EP (1) | EP1453539B1 (de) |
| JP (2) | JP4874522B2 (de) |
| AT (1) | ATE414534T1 (de) |
| AU (1) | AU2002347369A1 (de) |
| CA (1) | CA2469078A1 (de) |
| DE (1) | DE60229979D1 (de) |
| ES (1) | ES2316632T3 (de) |
| WO (1) | WO2003047618A2 (de) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE414534T1 (de) * | 2001-12-05 | 2008-12-15 | Circassia Ltd | Immunotherapeutische methoden und systeme |
| US7279295B2 (en) * | 2002-03-27 | 2007-10-09 | Phadia Ab | Allergen |
| CN1668737A (zh) * | 2002-05-16 | 2005-09-14 | 阿尔克-阿贝洛有限公司 | 重组Bet.V.1过敏原突变体及其方法和制备 |
| GB0307989D0 (en) * | 2003-04-07 | 2003-05-14 | Mcewen Lab Ltd | Therapeutic composition |
| KR20060096030A (ko) * | 2003-09-17 | 2006-09-05 | 베이비 부스트 인코퍼레이티드 | 알레르기 방지 방법 및 기구 |
| DE10351471A1 (de) * | 2003-11-04 | 2005-06-09 | Ursula Prof. Dr. Wiedermann-Schmidt | Polyvalente Allergievakzine |
| EP1773402A2 (de) * | 2004-06-17 | 2007-04-18 | Mannkind Corporation | Wirksamere immuntherapie mittels ergänzung diagnostischer verfahren mit therapeutischen verfahren |
| CN100374152C (zh) * | 2005-12-23 | 2008-03-12 | 中国农业大学 | 一种过敏性反应抑制剂 |
| JP2007189919A (ja) * | 2006-01-17 | 2007-08-02 | Osaka Prefecture Univ | イヌアレルギーに対する予防又は治療作用を有するポリペプチド |
| JP2007189920A (ja) * | 2006-01-17 | 2007-08-02 | Osaka Prefecture Univ | イヌアレルギーに対する予防又は治療作用を有するポリペプチド |
| AU2008211227B2 (en) | 2007-01-30 | 2014-04-17 | Epivax, Inc. | Regulatory T cell epitopes, compositions and uses thereof |
| WO2008092902A1 (en) * | 2007-01-30 | 2008-08-07 | Alk-Abelló A/S | Use of a first house dust mite group 2 allergen for treating allergy to a second house dust mite group 2 allergen |
| AU2013202871B2 (en) * | 2007-06-01 | 2015-10-22 | Circassia Limited | Vaccine peptide combinations against cat allergy |
| GB0710529D0 (en) * | 2007-06-01 | 2007-07-11 | Circassia Ltd | Vaccine |
| MX2010001779A (es) | 2007-08-15 | 2010-07-06 | Circassia Ltd | Peptidos para vacunas. |
| EP2153841B2 (de) | 2008-08-15 | 2015-11-11 | Circassia Limited | Impfstoff beinhaltend Amb a 1 Peptide zur Behandlung von Traubenkraut-Allergie |
| WO2010018384A1 (en) * | 2008-08-15 | 2010-02-18 | Circassia Limited | T-cell antigen peptide from allergen for stimulation of il-10 production |
| GB0821806D0 (en) * | 2008-11-28 | 2009-01-07 | Circassia Ltd | Compositions with reduced dimer formation |
| CN102438643B (zh) | 2008-11-30 | 2015-07-01 | 免疫桑特公司 | 用于治疗乳糜泻的组合物和方法 |
| HRP20150317T1 (hr) | 2009-02-05 | 2015-04-24 | Circassia Limited | Peptidi trave za cjepivo |
| GB201002559D0 (en) | 2010-02-15 | 2010-03-31 | Circassia Ltd | Birch peptides for vaccine |
| US20130004528A1 (en) * | 2010-02-26 | 2013-01-03 | Benaroya Research Institute | Direct analysis of antigen-specific immune response |
| WO2011112788A1 (en) * | 2010-03-12 | 2011-09-15 | Antigen Laboratories, Inc. | Methods of treating allergies with substantially phenol-free carriers |
| JP6062851B2 (ja) * | 2010-04-30 | 2017-01-18 | アロヴェイト・エルエルシー | 口腔粘膜を介してアレルギーを減感作するための方法、物品及びキット |
| WO2012148549A1 (en) | 2011-02-25 | 2012-11-01 | Benaroya Research Institute | Detection of an immune response |
| CN102793919A (zh) * | 2011-05-20 | 2012-11-28 | 日东电工株式会社 | 医药组合物及医药组合物的制造方法 |
| WO2013166453A2 (en) * | 2012-05-03 | 2013-11-07 | La Jolla Institute For Allergy And Immunology | T cell epitopes from cockroach and methods of making and using same |
| GB201208293D0 (en) | 2012-05-11 | 2012-06-20 | Circassia Ltd | Hydrochlorice salt of peptide |
| US11096994B2 (en) | 2012-10-30 | 2021-08-24 | Aravax Pty Ltd | Immunotherapeutic molecules and uses thereof |
| JP2014028820A (ja) * | 2013-08-30 | 2014-02-13 | China Agricultural Univ | アレルギー抑制剤の組成物及びキットならびにその使用方法 |
| WO2015038624A1 (en) | 2013-09-10 | 2015-03-19 | Immusant, Inc. | Dosage of a gluten peptide composition |
| EA035045B1 (ru) | 2013-09-19 | 2020-04-21 | АЛЛОВЕЙТ, ЭлЭлСи | Составы зубной пасты для доставки аллергенов в слизистую оболочку полости рта |
| CN121714673A (zh) | 2013-09-25 | 2026-03-24 | 阿拉沃克斯有限公司 | 新型免疫治疗组合物及其用途 |
| US10925924B2 (en) * | 2014-03-18 | 2021-02-23 | Apeptico Forschung Und Entwicklung Gmbh | Dry-powder peptide medicament |
| US10872313B2 (en) | 2015-06-02 | 2020-12-22 | ROCA Medical Ltd. | Method for repurposing NDC codes in a pharmaceutical database for venom derived allergens involved in venom immunotherapy |
| WO2016054038A1 (en) | 2014-09-29 | 2016-04-07 | Immusant, Inc. | Use of hla genetic status to assess or select treatment of celiac disease |
| US20160362205A1 (en) * | 2015-06-02 | 2016-12-15 | ROCA Medical Ltd. | Use of autoinjector for distributing antigens to the public |
| US10369215B2 (en) | 2015-06-02 | 2019-08-06 | ROCA Medical Ltd. | Predilution sets for distributing antigens |
| US10548974B2 (en) | 2015-06-02 | 2020-02-04 | ROCA Medical Ltd. | Therapeutic treatment kit for allergies based on DNA profiles |
| US20170021010A1 (en) * | 2015-07-21 | 2017-01-26 | David Phillip ERSTEIN | Allergy preventing dosage controlled food packets |
| JP7041923B2 (ja) * | 2016-03-03 | 2022-03-25 | 学校法人藤田学園 | 大豆アレルギーの抗原 |
| CN108265057B (zh) * | 2016-12-31 | 2019-10-18 | 江苏众红生物工程创药研究院有限公司 | 一种重组户尘螨2类变应原蛋白及其制备方法和应用 |
| CN108265059B (zh) * | 2016-12-31 | 2021-01-05 | 江苏众红生物工程创药研究院有限公司 | 一种重组粉尘螨2类变应原蛋白及其制备方法与应用 |
| JP7555788B2 (ja) * | 2020-10-30 | 2024-09-25 | アサヒグループホールディングス株式会社 | タンパク質の起源種判別方法 |
| CN113336862B (zh) * | 2021-07-05 | 2022-03-01 | 广东省科学院动物研究所 | 一种抗多发性硬化的重组蛋白及其制备方法和用途 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5358710A (en) * | 1989-12-01 | 1994-10-25 | Alec Sehon | Method for the suppression of an immune response |
| WO1994024281A1 (en) * | 1993-04-14 | 1994-10-27 | Immulogic Pharmaceutical Corporation | T cell epitopes of the major allergens from dermatophagoides (house dust mite) |
| AU2238395A (en) * | 1994-04-01 | 1995-10-23 | Immulogic Pharmaceutical Corporation | Haptenated peptides and uses thereof |
| GB2348808B (en) * | 1998-01-09 | 2003-03-19 | Circassia Ltd | Methods and compositions for desensitisation |
| ATE414534T1 (de) * | 2001-12-05 | 2008-12-15 | Circassia Ltd | Immunotherapeutische methoden und systeme |
-
2002
- 2002-12-05 AT AT02783303T patent/ATE414534T1/de not_active IP Right Cessation
- 2002-12-05 DE DE60229979T patent/DE60229979D1/de not_active Expired - Lifetime
- 2002-12-05 AU AU2002347369A patent/AU2002347369A1/en not_active Abandoned
- 2002-12-05 CA CA002469078A patent/CA2469078A1/en not_active Abandoned
- 2002-12-05 JP JP2003548873A patent/JP4874522B2/ja not_active Expired - Fee Related
- 2002-12-05 WO PCT/GB2002/005548 patent/WO2003047618A2/en not_active Ceased
- 2002-12-05 ES ES02783303T patent/ES2316632T3/es not_active Expired - Lifetime
- 2002-12-05 US US10/498,026 patent/US20060024334A1/en not_active Abandoned
- 2002-12-05 EP EP02783303A patent/EP1453539B1/de not_active Revoked
-
2009
- 2009-09-17 JP JP2009215825A patent/JP2009292838A/ja active Pending
-
2010
- 2010-08-20 US US12/860,216 patent/US20110142867A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2002347369A1 (en) | 2003-06-17 |
| ES2316632T3 (es) | 2009-04-16 |
| JP4874522B2 (ja) | 2012-02-15 |
| US20110142867A1 (en) | 2011-06-16 |
| AU2002347369A8 (en) | 2003-06-17 |
| WO2003047618A3 (en) | 2004-01-08 |
| JP2005518367A (ja) | 2005-06-23 |
| DE60229979D1 (de) | 2009-01-02 |
| CA2469078A1 (en) | 2003-06-12 |
| JP2009292838A (ja) | 2009-12-17 |
| US20060024334A1 (en) | 2006-02-02 |
| EP1453539B1 (de) | 2008-11-19 |
| EP1453539A2 (de) | 2004-09-08 |
| WO2003047618A2 (en) | 2003-06-12 |
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