BRPI0915813A2 - estabilizante e composição de vacina compreendendo um ou mais flavivírus atenuados vivos - Google Patents
estabilizante e composição de vacina compreendendo um ou mais flavivírus atenuados vivosInfo
- Publication number
- BRPI0915813A2 BRPI0915813A2 BRPI0915813-8A BRPI0915813A BRPI0915813A2 BR PI0915813 A2 BRPI0915813 A2 BR PI0915813A2 BR PI0915813 A BRPI0915813 A BR PI0915813A BR PI0915813 A2 BRPI0915813 A2 BR PI0915813A2
- Authority
- BR
- Brazil
- Prior art keywords
- vaccine composition
- stabilizer
- live attenuated
- vaccine
- attenuated flaviviruses
- Prior art date
Links
- 229960005486 vaccine Drugs 0.000 title abstract 10
- 239000000203 mixture Substances 0.000 title abstract 8
- 241000710831 Flavivirus Species 0.000 title abstract 4
- 230000002238 attenuated effect Effects 0.000 title abstract 4
- 239000003381 stabilizer Substances 0.000 title abstract 4
- 230000000087 stabilizing effect Effects 0.000 abstract 2
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24151—Methods of production or purification of viral material
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Oncology (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Mycology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Abstract
estabilizante para composições de vacina, composição de vacina aquosa em massa estabilizada, método de estabilização de um ou mais flavivírus atenuados vivos, composição de vacina seca, método para a preparação de uma vacina e kit de vacina flaviviral a presente invenção refere-se a um estabilizante para composições de vacina compreendendo um ou mais flavivírus atenuados vivos, a uma composição de vacina em massa estabilizada com este estabilizante, particularmente uma composição de vacina seca preparada a partir desta composição da vacina em massa, e a um método para a estabilização de um ou mais flavivírus atenuados vivos.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP08305390A EP2143440A1 (fr) | 2008-07-09 | 2008-07-09 | Agent stabilisant et composition vaccinale comprenant un ou plusieurs flavivirus vivants atténués |
EP08305390.0 | 2008-07-09 | ||
PCT/EP2009/004980 WO2010003670A1 (en) | 2008-07-09 | 2009-07-09 | Stabilizer and vaccine composition comprising one or more live attenuated flaviviruses |
Publications (2)
Publication Number | Publication Date |
---|---|
BRPI0915813A2 true BRPI0915813A2 (pt) | 2019-04-09 |
BRPI0915813B1 BRPI0915813B1 (pt) | 2022-02-08 |
Family
ID=39942863
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0915813-8A BRPI0915813B1 (pt) | 2008-07-09 | 2009-07-09 | Estabilizante para composições de vacina, composição de vacina aquosa em massa estabilizada, método de estabilização de um ou mais flavivírus atenuados vivos, composição de vacina seca, métodos para a preparação de vacinas e kit de vacina flaviviral |
Country Status (17)
Country | Link |
---|---|
US (2) | US8142795B2 (pt) |
EP (3) | EP2143440A1 (pt) |
JP (1) | JP5586598B2 (pt) |
KR (1) | KR101679723B1 (pt) |
CN (1) | CN102089002B (pt) |
AR (1) | AR072796A1 (pt) |
AU (1) | AU2009267401B2 (pt) |
BR (1) | BRPI0915813B1 (pt) |
CA (1) | CA2729758C (pt) |
DK (1) | DK2310048T3 (pt) |
ES (1) | ES2429130T3 (pt) |
IL (1) | IL210289A0 (pt) |
MX (1) | MX2011000312A (pt) |
MY (1) | MY150613A (pt) |
TW (1) | TWI460190B (pt) |
WO (1) | WO2010003670A1 (pt) |
ZA (1) | ZA201100107B (pt) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8557253B2 (en) * | 2009-10-07 | 2013-10-15 | Sanofi Pasteur Sa | Stabilizing excipient for inactivated whole virus vaccine |
WO2011135393A1 (es) * | 2010-04-27 | 2011-11-03 | Universidad Manuela Beltran | Vacuna biologica autologa contra el cancer |
FR2960781B1 (fr) * | 2010-06-07 | 2013-11-22 | Sanofi Pasteur | Preparation d'un vaccin oral sec stabilise, compose d'un virus vivant attenue |
WO2012028315A1 (en) | 2010-09-02 | 2012-03-08 | Sanofi Pasteur Sa | A stabilizer for the preparation of a dry polio injectable vaccine composition |
ES2626297T3 (es) | 2011-08-12 | 2017-07-24 | Merial, Inc. | Preservación asistida por vacío de productos biológicos, en particular de vacunas |
EP3246400B1 (en) | 2012-01-09 | 2019-10-23 | Sanofi Pasteur Biologics, LLC | Purification of herpes virus |
WO2013172467A1 (ja) * | 2012-05-14 | 2013-11-21 | 帝人株式会社 | 放射線滅菌耐性蛋白質組成物 |
WO2013177172A2 (en) * | 2012-05-21 | 2013-11-28 | Sanofi Pasteur Limited | Herpesvirus compositions and related methods |
EP3932422A1 (en) | 2012-07-24 | 2022-01-05 | Sanofi Pasteur | Vaccine compositions for the prevention of dengue virus infection |
CN104812408A (zh) | 2012-07-24 | 2015-07-29 | 赛诺菲巴斯德有限公司 | 用于防止登革热病毒感染的疫苗组合物 |
US9314519B2 (en) | 2012-08-21 | 2016-04-19 | Intervet Inc. | Liquid stable virus vaccines |
BR112015012515B1 (pt) | 2012-11-30 | 2023-04-11 | Sanofi Pasteur | Uso de antígenos, construções de ácido nucleico ou vetores virais capazes de expressar uma partícula do tipo vírus (vlp) da dengue e de uma vacina contra sarampo, uma vacina contra caxumba e uma vacina contra rubéola |
US9393298B2 (en) | 2013-03-15 | 2016-07-19 | Intervet Inc. | Liquid stable bovine virus vaccines |
US9480739B2 (en) | 2013-03-15 | 2016-11-01 | Intervet Inc. | Bovine virus vaccines that are liquid stable |
AR097762A1 (es) | 2013-09-27 | 2016-04-13 | Intervet Int Bv | Formulaciones secas de vacunas que son estables a temperatura ambiente |
US9782470B2 (en) | 2013-10-16 | 2017-10-10 | Merck Sharp & Dohme Corp. | Method of obtaining thermostable dried vaccine formulations |
US10429129B2 (en) | 2013-10-16 | 2019-10-01 | Merck Sharp & Dohme Corp. | Method of microwave vacuum drying spherical-shaped pellets of biological materials |
AR099470A1 (es) | 2014-02-17 | 2016-07-27 | Intervet Int Bv | Vacunas de virus de aves de corral líquidas |
TWI670085B (zh) | 2014-02-19 | 2019-09-01 | 荷蘭商英特威國際公司 | 液體穩定之豬病毒疫苗 |
NZ741421A (en) | 2014-05-14 | 2023-05-26 | Vitamfero S A | Methods for freeze-drying and rehydrating biologics |
EP3188751A1 (en) | 2014-09-02 | 2017-07-12 | Sanofi Pasteur | Vaccine compositions against dengue virus diseases |
EP3316905A1 (en) | 2015-07-03 | 2018-05-09 | Sanofi Pasteur | Concomitant dengue and yellow fever vaccination |
US10004795B2 (en) * | 2015-09-08 | 2018-06-26 | Fundacao Butantan | Process for preparing an attenuated tetravalent dengue vaccine |
CN106667944A (zh) * | 2015-11-11 | 2017-05-17 | 北京泰德制药股份有限公司 | 含有前列腺素类药物的缓释制剂 |
TWI766876B (zh) * | 2016-08-03 | 2022-06-11 | 美商武田疫苗股份有限公司 | 用於與經改良之調配物一起穩定黃病毒的組成物及方法 |
JP7051132B2 (ja) * | 2016-09-16 | 2022-04-11 | ロイコケア・アクチェンゲゼルシャフト | ワクチン接種または遺伝子治療のための効率的なウイルスベクターベースの組成物を得るための新規方法 |
GB201704126D0 (en) * | 2017-03-15 | 2017-04-26 | Blom Nihlén Kim Andrea | Vaccine |
CA3062549A1 (en) * | 2017-05-15 | 2018-11-22 | Janssen Vaccines & Prevention B.V. | Stable virus-containing composition |
CN111065732A (zh) | 2017-09-11 | 2020-04-24 | Imba-莫利库尔生物技术研究所 | 肿瘤类器官模型 |
WO2019069130A1 (en) | 2017-10-05 | 2019-04-11 | Sanofi Pasteur | COMPOSITIONS FOR RECALL VACCINATION AGAINST DENGUE |
JP7261239B2 (ja) | 2017-10-16 | 2023-04-19 | セラム インスティチュート オブ インディア プライベイト リミテッド | 弱毒生組換えフラビウイルスなどから成る安定したワクチン組成物およびその調製方法 |
MX2020005857A (es) | 2017-12-07 | 2020-09-09 | Merck Sharp & Dohme | Formulaciones de composiciones de vacuna contra el virus del dengue. |
CN108938574B (zh) * | 2018-08-14 | 2020-10-16 | 江苏省农业科学院 | 猪伪狂犬病活疫苗冻干耐热保护剂、其制备方法及用途 |
US20220193222A1 (en) * | 2018-11-30 | 2022-06-23 | Vaccine Stabilization Institute | Viral formulations containing amino acids |
KR102544928B1 (ko) * | 2022-12-28 | 2023-06-20 | 주식회사 중앙백신연구소 | 아미노산을 유효성분으로 함유하는 동물용 백신 또는 진단용 항원의 안정성 증진용 조성물 및 이의 용도 |
Family Cites Families (49)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3162019A (en) | 1962-11-16 | 1964-12-22 | Bethlehem Steel Corp | Method and apparatus for freezing liquids to be used in a freeze-drying process |
GB1195363A (en) | 1966-06-17 | 1970-06-17 | Struthers Scientific Int Corp | Freeze Drying |
US3313032A (en) | 1966-07-28 | 1967-04-11 | George J Malecki | Freeze-drying process and apparatus |
US3655838A (en) | 1969-03-20 | 1972-04-11 | Organon | Method of pelletizing analytical or immunological reagents |
DE2659546A1 (de) | 1976-12-30 | 1978-07-13 | Boehringer Mannheim Gmbh | Verfahren zur herstellung von gefrorenen granulaten |
US4211015A (en) | 1978-01-18 | 1980-07-08 | Baxter Travenol Laboratories, Inc. | Method and apparatus for making novel particulate compositions |
FR2505657A1 (fr) * | 1981-05-13 | 1982-11-19 | Pasteur Institut | Perfectionnements apportes aux agents de stabilisation de virus vivants pour la preparation de vaccins, et vaccins stabilises contenant lesdits agents de stabilisation |
GB8802142D0 (en) * | 1988-02-01 | 1988-03-02 | Air Prod & Chem | Method of freezing liquid & pasty products & freezer for carrying out said method |
ES2153223T3 (es) | 1991-09-19 | 2001-02-16 | Us Health | Flavivirus quimericos y/o flavivirus de crecimiento restringido. |
US5307640A (en) | 1993-01-25 | 1994-05-03 | E. I. Du Pont De Nemours And Company | Apparatus and method for producing frozen particles of a liquid |
US5922253A (en) | 1995-05-18 | 1999-07-13 | Alkermes Controlled Therapeutics, Inc. | Production scale method of forming microparticles |
AU6093296A (en) | 1995-06-07 | 1996-12-30 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Infectious dengue 2 virus pdk-53 as quadravalent vaccine |
FR2742756B1 (fr) * | 1995-12-22 | 1998-04-03 | Pasteur Merieux Serums Vacc | Stabilisants pour vaccins vivants, vaccins les contenant et procedes pour leur preparation |
IL120202A (en) | 1996-03-07 | 2001-03-19 | Akzo Nobel Nv | Container with freeze-dried vaccine components |
US6962708B1 (en) * | 1997-02-28 | 2005-11-08 | Acambis, Inc. | Chimeric flavivirus vaccines |
JP4504464B2 (ja) | 1997-02-28 | 2010-07-14 | サノフィ パスツール バイオロジクス カンパニー | キメラフラビウイルスワクチン |
BRPI9701774B8 (pt) | 1997-04-11 | 2015-09-29 | Fundação Oswaldo Cruz Fiocruz | cdna mutante e infeccioso do vírus da febre amarela, constructo de dna, vírus recombinante de febre amarela e vacina para humanos contra infecções de febre amarela. |
US6210683B1 (en) * | 1997-09-05 | 2001-04-03 | Merck & Co., Inc. | Stabilizers containing recombinant human serum albumin for live virus vaccines |
CA2365728A1 (en) | 1999-03-26 | 2000-10-05 | Walter Reed Army Institute Of Research | Attenuated dengue-1 virus vaccine |
AU4040400A (en) | 1999-03-26 | 2000-10-16 | Walter Reed Army Institute Of Research | Attenuated dengue-4 virus vaccine |
EP1165128A2 (en) | 1999-03-26 | 2002-01-02 | Walter Reed Army Institute of Research | Attenuated dengue-2 virus vaccine |
CA2368790A1 (en) | 1999-03-26 | 2000-10-05 | Walter Reed Army Institute Of Research | Attenuated dengue-3 virus vaccine |
CA2941182A1 (en) | 2000-02-16 | 2001-08-23 | The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services | Avirulent, immunogenic flavivirus chimeras |
PT1159968E (pt) | 2000-05-30 | 2008-11-20 | Univ Mahidol | Estirpes atenuadas de vírus do dengue e a sua utilização numa composição de vacina |
JP2004517699A (ja) | 2001-01-30 | 2004-06-17 | ボード オブ リージェンツ ユニバーシティ オブ テキサス システム | 液体中への噴霧凍結によるナノ粒子およびミクロ粒子の製造方法 |
AT410634B (de) * | 2001-02-21 | 2003-06-25 | Franz X Dr Heinz | Attenuierte lebendimpfstoffe |
GB2372991B (en) | 2001-03-09 | 2004-11-17 | Fiocruz Fundacao Oswaldo Cruz | Flavivirus expression vector |
DE10124902A1 (de) | 2001-05-22 | 2002-11-28 | Bayer Ag | Partikuläre Feststoffe oberflächenaktiver Verbindungen |
CA3060687C (en) | 2001-05-22 | 2021-05-04 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Development of mutations useful for attenuating dengue viruses and chimeric dengue viruses |
ES2439724T3 (es) | 2001-06-01 | 2014-01-24 | Sanofi Pasteur Biologics, Llc | Vectores de flavivirus quiméricos |
US7459160B2 (en) | 2002-01-15 | 2008-12-02 | Acambis Inc. | Chimeric flaviviruses |
US20050002968A1 (en) | 2002-01-15 | 2005-01-06 | Monath Thomas P. | Flavivirus vaccines |
WO2003102166A2 (en) | 2002-02-26 | 2003-12-11 | Maxygen, Inc. | Novel flavivirus antigens |
EP2591771A1 (en) * | 2002-04-11 | 2013-05-15 | MedImmune, LLC | Preservation of bioactive materials by freeze dried foam |
US20030215455A1 (en) * | 2002-05-14 | 2003-11-20 | Bailey Reynolds | Vaccine stabilizer and method of use |
AU2003239932A1 (en) | 2002-05-31 | 2003-12-19 | Acambis, Inc. | Tetravalent dengue vaccines |
EP1575979B1 (en) | 2002-11-15 | 2009-12-23 | Sanofi Pasteur Biologics Co. | West nile virus vaccine |
WO2004052293A2 (en) * | 2002-12-11 | 2004-06-24 | Hawaii Biotech, Inc. | Recombinant vaccine against flavivirus infection |
US7836606B2 (en) | 2004-07-23 | 2010-11-23 | Bayer Technology Services Gmbh | Sterile freezing, drying, storing, assaying and filling process |
MX2007015873A (es) | 2005-06-17 | 2008-04-22 | Sanofi Pasteur | Cepa atenuada de virus de dengue serotipo 1. |
BRPI0613287A2 (pt) | 2005-06-17 | 2010-12-28 | Sanofi Pasteur | cepa do vìrus da dengue-2 vivo atenuada, composição imunogênica, composição de vacina, ácido nucléico isolado, poliproteìna isolada codificadas pela seq id n .1 ou fragmentos desta e fragmento da poliproteìna |
CN101237888A (zh) * | 2005-08-04 | 2008-08-06 | 惠氏公司 | 畜禽疫苗的稳定剂 |
JP5138601B2 (ja) * | 2005-11-21 | 2013-02-06 | サノフィ パストゥール リミテッド | 組換えウイルス安定化製剤 |
FR2903605A1 (fr) * | 2006-07-12 | 2008-01-18 | Sanofi Pasteur Sa | Methode d'immunisation contre les quatres serotypes de la dengue |
US20100129379A1 (en) | 2006-09-25 | 2010-05-27 | John Carpenter | Stabilized antibody formulations and uses thereof |
FR2906724B1 (fr) * | 2006-10-04 | 2009-03-20 | Sanofi Pasteur Sa | Methode d'immunisation contre les 4 serotypes de la dengue. |
EP2851087B1 (en) | 2006-11-07 | 2017-04-19 | Sanofi Pasteur Biologics, LLC | Stabilization of vaccines by lyophilization |
FR2909286B1 (fr) * | 2006-12-01 | 2012-06-08 | Sanofi Pasteur | Methode d'immunisation contre les 4 serotypes de la dengue |
KR102134980B1 (ko) * | 2007-04-06 | 2020-07-16 | 다케다 백신즈 인코포레이티드 | 살아있는 약독화된 바이러스를 위한 방법 및 조성물 |
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2008
- 2008-07-09 EP EP08305390A patent/EP2143440A1/fr not_active Withdrawn
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2009
- 2009-07-06 AR ARP090102524A patent/AR072796A1/es not_active Application Discontinuation
- 2009-07-08 TW TW098123127A patent/TWI460190B/zh active
- 2009-07-09 AU AU2009267401A patent/AU2009267401B2/en active Active
- 2009-07-09 MX MX2011000312A patent/MX2011000312A/es active IP Right Grant
- 2009-07-09 DK DK09793888.0T patent/DK2310048T3/da active
- 2009-07-09 BR BRPI0915813-8A patent/BRPI0915813B1/pt active IP Right Grant
- 2009-07-09 MY MYPI20105959 patent/MY150613A/en unknown
- 2009-07-09 EP EP13183819.5A patent/EP2687229A1/en not_active Withdrawn
- 2009-07-09 CN CN200980127083.8A patent/CN102089002B/zh active Active
- 2009-07-09 CA CA2729758A patent/CA2729758C/en active Active
- 2009-07-09 EP EP09793888.0A patent/EP2310048B1/en active Active
- 2009-07-09 US US12/500,156 patent/US8142795B2/en active Active
- 2009-07-09 ES ES09793888T patent/ES2429130T3/es active Active
- 2009-07-09 KR KR1020117000182A patent/KR101679723B1/ko active IP Right Grant
- 2009-07-09 JP JP2011517028A patent/JP5586598B2/ja active Active
- 2009-07-09 WO PCT/EP2009/004980 patent/WO2010003670A1/en active Application Filing
-
2010
- 2010-12-27 IL IL210289A patent/IL210289A0/en active IP Right Grant
-
2011
- 2011-01-04 ZA ZA2011/00107A patent/ZA201100107B/en unknown
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2012
- 2012-03-26 US US13/429,542 patent/US20130028934A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
DK2310048T3 (da) | 2013-10-07 |
BRPI0915813B1 (pt) | 2022-02-08 |
EP2310048B1 (en) | 2013-09-11 |
CN102089002A (zh) | 2011-06-08 |
CA2729758C (en) | 2017-03-07 |
EP2687229A1 (en) | 2014-01-22 |
EP2310048A1 (en) | 2011-04-20 |
US8142795B2 (en) | 2012-03-27 |
US20100015180A1 (en) | 2010-01-21 |
US20130028934A1 (en) | 2013-01-31 |
JP5586598B2 (ja) | 2014-09-10 |
MX2011000312A (es) | 2011-03-01 |
ES2429130T3 (es) | 2013-11-13 |
WO2010003670A1 (en) | 2010-01-14 |
CA2729758A1 (en) | 2010-01-14 |
IL210289A0 (en) | 2011-03-31 |
AU2009267401B2 (en) | 2014-12-11 |
AU2009267401A1 (en) | 2010-01-14 |
MY150613A (en) | 2014-01-30 |
AR072796A1 (es) | 2010-09-22 |
EP2143440A1 (fr) | 2010-01-13 |
TW201014868A (en) | 2010-04-16 |
ZA201100107B (en) | 2012-03-28 |
CN102089002B (zh) | 2014-12-10 |
KR20110053325A (ko) | 2011-05-20 |
KR101679723B1 (ko) | 2016-11-25 |
TWI460190B (zh) | 2014-11-11 |
JP2011527300A (ja) | 2011-10-27 |
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