BRPI0914260A2 - método de preparação de compostos bicíclicos à saber de imidazol - Google Patents

método de preparação de compostos bicíclicos à saber de imidazol

Info

Publication number
BRPI0914260A2
BRPI0914260A2 BRPI0914260A BRPI0914260A BRPI0914260A2 BR PI0914260 A2 BRPI0914260 A2 BR PI0914260A2 BR PI0914260 A BRPI0914260 A BR PI0914260A BR PI0914260 A BRPI0914260 A BR PI0914260A BR PI0914260 A2 BRPI0914260 A2 BR PI0914260A2
Authority
BR
Brazil
Prior art keywords
preparation
bicyclic compounds
compounds namely
imidazole
namely imidazole
Prior art date
Application number
BRPI0914260A
Other languages
English (en)
Inventor
Jason Guohua Chen
Renmao Liu
Weifeng Hu
Wenxue Wu
Xiaogen Yang
Yuelie Lu
Original Assignee
Lexicon Pharmaceuiticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41402541&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0914260(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lexicon Pharmaceuiticals Inc filed Critical Lexicon Pharmaceuiticals Inc
Publication of BRPI0914260A2 publication Critical patent/BRPI0914260A2/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D261/00Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/04Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BRPI0914260A 2008-06-18 2009-06-16 método de preparação de compostos bicíclicos à saber de imidazol BRPI0914260A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7339908P 2008-06-18 2008-06-18
PCT/US2009/047495 WO2010008734A2 (en) 2008-06-18 2009-06-16 Methods of Preparing Imidazole-Based Bicyclic Compounds

Publications (1)

Publication Number Publication Date
BRPI0914260A2 true BRPI0914260A2 (pt) 2015-11-03

Family

ID=41402541

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0914260A BRPI0914260A2 (pt) 2008-06-18 2009-06-16 método de preparação de compostos bicíclicos à saber de imidazol

Country Status (19)

Country Link
US (1) US7968726B2 (pt)
EP (1) EP2318380B1 (pt)
JP (1) JP2011524916A (pt)
KR (1) KR20110019433A (pt)
CN (1) CN102066344A (pt)
AR (1) AR072152A1 (pt)
AU (1) AU2009271409B2 (pt)
BR (1) BRPI0914260A2 (pt)
CA (1) CA2728097C (pt)
CL (1) CL2009001437A1 (pt)
CO (1) CO6341619A2 (pt)
ES (1) ES2604313T3 (pt)
IL (1) IL209817A0 (pt)
MX (1) MX2010013817A (pt)
PE (1) PE20100086A1 (pt)
RU (1) RU2011101593A (pt)
TW (1) TW201002698A (pt)
UY (1) UY31899A (pt)
WO (1) WO2010008734A2 (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2401555T3 (es) * 2008-06-18 2013-04-22 Lexicon Pharmaceuticals, Inc. Formas sólidas de (1R,2S,3R)-1-(2-(isoxazol-3-il)-1H-imidazol-4-il)butano-1,2,3,4-tetraol y métodos de utilización de las mismas
WO2013049272A2 (en) 2011-09-29 2013-04-04 Theraceutix, Llc Composition and method for treatment of symptoms associated with various skin conditions

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4567194A (en) * 1983-03-10 1986-01-28 The Coca-Cola Company 2-Acylimidazole compounds, their synthesis and use as medicinal agents
US4587194A (en) * 1984-11-20 1986-05-06 The Mead Corporation Photosensitive material employing microcapsules having different photographic speeds
ZA974811B (en) 1996-05-31 1997-12-30 Univ Wollongong Novel therapeutic compounds.
WO2007002458A2 (en) * 2005-06-28 2007-01-04 Merck & Co., Inc. Non-nucleoside reverse transcriptase inhibitors
US7649098B2 (en) 2006-02-24 2010-01-19 Lexicon Pharmaceuticals, Inc. Imidazole-based compounds, compositions comprising them and methods of their use
TW200848029A (en) * 2007-03-01 2008-12-16 Lexicon Pharmaceuticals Inc Heterocyclic compounds, compositions comprising them and methods of their use
UY31013A1 (es) 2007-04-12 2008-09-02 Lexicon Pharmaceuticals Inc Metodos para prepar compuestos basados en imidazol
ES2401555T3 (es) 2008-06-18 2013-04-22 Lexicon Pharmaceuticals, Inc. Formas sólidas de (1R,2S,3R)-1-(2-(isoxazol-3-il)-1H-imidazol-4-il)butano-1,2,3,4-tetraol y métodos de utilización de las mismas

Also Published As

Publication number Publication date
EP2318380B1 (en) 2016-08-24
CO6341619A2 (es) 2011-11-21
MX2010013817A (es) 2011-02-24
KR20110019433A (ko) 2011-02-25
CL2009001437A1 (es) 2010-08-20
WO2010008734A3 (en) 2010-03-11
EP2318380A2 (en) 2011-05-11
IL209817A0 (en) 2011-02-28
AU2009271409A1 (en) 2010-01-21
WO2010008734A2 (en) 2010-01-21
US20090318705A1 (en) 2009-12-24
TW201002698A (en) 2010-01-16
PE20100086A1 (es) 2010-02-08
CA2728097A1 (en) 2010-01-21
AR072152A1 (es) 2010-08-11
JP2011524916A (ja) 2011-09-08
AU2009271409B2 (en) 2014-01-30
ES2604313T3 (es) 2017-03-06
CA2728097C (en) 2017-01-03
RU2011101593A (ru) 2012-07-27
US7968726B2 (en) 2011-06-28
UY31899A (es) 2010-01-29
CN102066344A (zh) 2011-05-18

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]