BRPI0909672A2 - detecção de moléculas específicas para hepatocarcinoma - Google Patents

detecção de moléculas específicas para hepatocarcinoma

Info

Publication number
BRPI0909672A2
BRPI0909672A2 BRPI0909672A BRPI0909672A BRPI0909672A2 BR PI0909672 A2 BRPI0909672 A2 BR PI0909672A2 BR PI0909672 A BRPI0909672 A BR PI0909672A BR PI0909672 A BRPI0909672 A BR PI0909672A BR PI0909672 A2 BRPI0909672 A2 BR PI0909672A2
Authority
BR
Brazil
Prior art keywords
detection
hepatocellular carcinoma
specific molecules
molecules
specific
Prior art date
Application number
BRPI0909672A
Other languages
English (en)
Inventor
Atsuhiko Kato
Hiroaki Kataoka
Hirotake Takai
Masami Suzuki
Masamichi Sugimoto
Original Assignee
Chugai Pharmaceutical Co Ltd
Univ Miyazaki
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd, Univ Miyazaki filed Critical Chugai Pharmaceutical Co Ltd
Publication of BRPI0909672A2 publication Critical patent/BRPI0909672A2/pt
Publication of BRPI0909672B1 publication Critical patent/BRPI0909672B1/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57438—Specifically defined cancers of liver, pancreas or kidney
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/303—Liver or Pancreas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
BRPI0909672A 2008-03-17 2009-03-16 método de imunoensaio in vitro para detecção da presença de células de câncer de fígado em um indivíduo, método para classificação de células de câncer de fígado presentes em um indivíduo, método in vitro para determinação de administrar ou não um agente anticâncer contendo um anticorpo anti-glipicano 3 a um indivíduo, e método in vitro para determinação de uma dose de um agente anticâncer contendo um anticorpo anti-glipicano 3 no tratamento de câncer de fígado em um indivíduo BRPI0909672B1 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2008068316 2008-03-17
PCT/JP2009/055567 WO2009116659A1 (ja) 2008-03-17 2009-03-16 抗グリピカン３抗体を用いる肝癌細胞の検出法

Publications (2)

Publication Number Publication Date
BRPI0909672A2 true BRPI0909672A2 (pt) 2015-12-01
BRPI0909672B1 BRPI0909672B1 (pt) 2018-09-18

Family

ID=41091056

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0909672A BRPI0909672B1 (pt) 2008-03-17 2009-03-16 método de imunoensaio in vitro para detecção da presença de células de câncer de fígado em um indivíduo, método para classificação de células de câncer de fígado presentes em um indivíduo, método in vitro para determinação de administrar ou não um agente anticâncer contendo um anticorpo anti-glipicano 3 a um indivíduo, e método in vitro para determinação de uma dose de um agente anticâncer contendo um anticorpo anti-glipicano 3 no tratamento de câncer de fígado em um indivíduo

Country Status (12)

Country Link
US (1) US8663929B2 (pt)
EP (1) EP2270509B1 (pt)
JP (1) JP5619603B2 (pt)
KR (1) KR20110005812A (pt)
CN (1) CN102027372A (pt)
AU (1) AU2009226423B2 (pt)
BR (1) BRPI0909672B1 (pt)
CA (1) CA2718707C (pt)
IL (1) IL208167A0 (pt)
MX (1) MX2010010136A (pt)
TW (1) TW200949248A (pt)
WO (1) WO2009116659A1 (pt)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004022597A1 (ja) * 2002-09-04 2004-03-18 Chugai Seiyaku Kabushiki Kaisha Gpc3の血中可溶化ｎ端ﾍﾟﾌﾟﾁﾄﾞに対する抗体
EP2314317A3 (en) * 2004-07-09 2011-06-29 Chugai Seiyaku Kabushiki Kaisha Anti-glypican 3 antibody
BRPI0518279A2 (pt) * 2004-10-26 2008-11-11 Chugai Pharmaceutical Co Ltd anticorpo antiglipicam 3 tendo cadeia de aÇécar modificada
US20070087005A1 (en) 2005-10-14 2007-04-19 Lazar Gregory A Anti-glypican-3 antibody
SG11201407972RA (en) 2012-06-01 2015-01-29 Us Health High-affinity monoclonal antibodies to glypican-3 and use thereof
TWI693073B (zh) * 2012-12-21 2020-05-11 日商中外製藥股份有限公司 對ｇｐｃ３標的治療劑療法為有效之患者投與的ｇｐｃ３標的治療劑
EP4119947A1 (en) 2012-12-21 2023-01-18 Chugai Seiyaku Kabushiki Kaisha Gpc3-targeting drug which is administered to patient responsive to gpc3-targeting drug therapy
EP3088890B1 (en) 2013-12-24 2020-09-23 Chugai Seiyaku Kabushiki Kaisha Method for measuring soluble gpc3 protein
EP3141603A4 (en) 2014-05-08 2017-12-27 Chugai Seiyaku Kabushiki Kaisha Gpc3-targeted therapeutic agent for administration to patients for whom gpc3-targeted therapeutic agent therapy is effective
MA40764A (fr) 2014-09-26 2017-08-01 Chugai Pharmaceutical Co Ltd Agent thérapeutique induisant une cytotoxicité
US11376326B2 (en) 2015-07-01 2022-07-05 Chugai Seiyaku Kabushiki Kaisha GPC3-targeting therapeutic agent which is administered to patient for whom the GPC3-targeting therapeutic agent is effective
KR20170007181A (ko) 2015-07-10 2017-01-18 3스캔 인크. 조직학적 염색제의 공간 다중화
CN105126123B (zh) * 2015-09-29 2018-04-03 南通大学 纳米探针的制备方法、基于天然产物单体和纳米探针的纳米药物的制备方法及应用
CN105112046A (zh) * 2015-09-29 2015-12-02 南通大学 核壳结构量子点的制备方法、靶向肿瘤标志物gpc-3的荧光纳米探针及其制备方法
CN105759039A (zh) * 2016-01-29 2016-07-13 山东康力医疗器械科技有限公司 磷酯酰肌醇蛋白聚糖3检测试剂盒
JP6292564B2 (ja) * 2016-03-10 2018-03-14 シスメックス株式会社 肝細胞がん患者の再発リスク予測を補助する方法、装置、コンピュータプログラム製品及びキット
WO2019168085A1 (ja) * 2018-02-28 2019-09-06 日東紡績株式会社 固定化細胞又はｆｆｐｅ組織切片から抗原性を増強した細胞核を脱離する方法並びにそのための抗原賦活剤及びキット
WO2020086758A1 (en) 2018-10-23 2020-04-30 Dragonfly Therapeutics, Inc. Heterodimeric fc-fused proteins
JP2023522972A (ja) 2020-04-22 2023-06-01 ドラゴンフライ セラピューティクス， インコーポレイテッド ヘテロ二量体Ｆｃ融合タンパク質のための製剤、投薬量レジメン、及び製造工程
CN113052228A (zh) * 2021-03-22 2021-06-29 山西三友和智慧信息技术股份有限公司 一种基于SE-Inception的肝癌病理切片分类方法
IL312540A (en) 2021-11-16 2024-07-01 Sotio Biotech Inc Treatment of patients with myxoid/round cell liposarcoma
CN117607440B (zh) * 2023-11-28 2024-05-14 中拓生物有限公司 一种磷脂酰肌醇蛋白聚糖3蛋白测定试剂盒及其制备方法和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5225325A (en) * 1990-03-02 1993-07-06 Ventana Medical Systems, Inc. Immunohistochemical staining method and reagents therefor
WO2004022597A1 (ja) 2002-09-04 2004-03-18 Chugai Seiyaku Kabushiki Kaisha Gpc3の血中可溶化ｎ端ﾍﾟﾌﾟﾁﾄﾞに対する抗体
ES2324029T3 (es) * 2002-05-23 2009-07-29 Sunnybrook And Women's College Health Sciences Centre Diagnostico de carcinoma hepatocelular.
EP2314317A3 (en) 2004-07-09 2011-06-29 Chugai Seiyaku Kabushiki Kaisha Anti-glypican 3 antibody
JP5141034B2 (ja) 2006-06-20 2013-02-13 日産自動車株式会社 レーザ加工装置およびレーザ加工方法

Also Published As

Publication number Publication date
JP5619603B2 (ja) 2014-11-05
US20110091907A1 (en) 2011-04-21
MX2010010136A (es) 2011-02-23
JPWO2009116659A1 (ja) 2011-07-21
EP2270509B1 (en) 2014-01-15
AU2009226423B2 (en) 2014-11-27
BRPI0909672B1 (pt) 2018-09-18
CA2718707A1 (en) 2009-09-24
WO2009116659A1 (ja) 2009-09-24
EP2270509A4 (en) 2011-07-13
KR20110005812A (ko) 2011-01-19
CN102027372A (zh) 2011-04-20
EP2270509A1 (en) 2011-01-05
US8663929B2 (en) 2014-03-04
IL208167A0 (en) 2010-12-30
AU2009226423A1 (en) 2009-09-24
TW200949248A (en) 2009-12-01
CA2718707C (en) 2018-01-02

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Legal Events

Date Code Title Description
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 16/03/2009, OBSERVADAS AS CONDICOES LEGAIS.

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 14A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2714 DE 10-01-2023 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.