BRPI0907224A2 - formulações narcórticas em emulsão para tratamento de dor cirúrgica - Google Patents

formulações narcórticas em emulsão para tratamento de dor cirúrgica

Info

Publication number
BRPI0907224A2
BRPI0907224A2 BRPI0907224-1A BRPI0907224A BRPI0907224A2 BR PI0907224 A2 BRPI0907224 A2 BR PI0907224A2 BR PI0907224 A BRPI0907224 A BR PI0907224A BR PI0907224 A2 BRPI0907224 A2 BR PI0907224A2
Authority
BR
Brazil
Prior art keywords
emulsion formulations
narcotic
surgical pain
emulsion
methods
Prior art date
Application number
BRPI0907224-1A
Other languages
English (en)
Portuguese (pt)
Inventor
Nabeta Kiichiro
Hibi Toru
Original Assignee
Teikoku Pharma Usa, Inc.
Techno Guard Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teikoku Pharma Usa, Inc., Techno Guard Co., Ltd. filed Critical Teikoku Pharma Usa, Inc.
Publication of BRPI0907224A2 publication Critical patent/BRPI0907224A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4468—Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BRPI0907224-1A 2008-05-15 2009-04-28 formulações narcórticas em emulsão para tratamento de dor cirúrgica BRPI0907224A2 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US5357108P 2008-05-15 2008-05-15
US61/053,571 2008-05-15
US12/424,382 2009-04-15
US12/424,382 US20090286832A1 (en) 2008-05-15 2009-04-15 Narcotic emulsion formulations for treatment of surgical pain
PCT/US2009/041991 WO2009140059A2 (en) 2008-05-15 2009-04-28 Narcotic emulsion formulations for treatment of surgical pain

Publications (1)

Publication Number Publication Date
BRPI0907224A2 true BRPI0907224A2 (pt) 2019-02-26

Family

ID=41316744

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0907224-1A BRPI0907224A2 (pt) 2008-05-15 2009-04-28 formulações narcórticas em emulsão para tratamento de dor cirúrgica

Country Status (16)

Country Link
US (1) US20090286832A1 (enExample)
EP (1) EP2276440A4 (enExample)
JP (2) JP5689053B2 (enExample)
KR (1) KR101361479B1 (enExample)
CN (1) CN101938963A (enExample)
AR (1) AR071779A1 (enExample)
AU (1) AU2009246713B2 (enExample)
BR (1) BRPI0907224A2 (enExample)
CA (1) CA2710546A1 (enExample)
EA (1) EA201000991A1 (enExample)
IL (1) IL209145A0 (enExample)
MX (1) MX2010007698A (enExample)
NZ (1) NZ586461A (enExample)
TW (2) TWI413531B (enExample)
WO (1) WO2009140059A2 (enExample)
ZA (1) ZA201004392B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090286832A1 (en) * 2008-05-15 2009-11-19 Kiichiro Nabeta Narcotic emulsion formulations for treatment of surgical pain
KR101564058B1 (ko) * 2009-02-26 2015-10-29 테이코쿠 팔마 유에스에이, 인코포레이티드 암 통증 치료용 마취 유상액 제제
JP6081240B2 (ja) * 2013-03-13 2017-02-15 テルモ株式会社 レミフェンタニル注射液剤
EP3192509B1 (en) 2014-09-12 2021-03-31 Terumo Kabushiki Kaisha Remifentanil injection
WO2021252449A1 (en) * 2020-06-08 2021-12-16 Harm Reduction Therapeutics, Inc. Sterilized formulations

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0647533B2 (ja) * 1984-08-10 1994-06-22 裕 水島 ４−ビフエニリル酢酸系化合物含有脂肪乳剤
US4816247A (en) * 1985-09-11 1989-03-28 American Cyanamid Company Emulsion compositions for administration of sparingly water soluble ionizable hydrophobic drugs
ATE183092T1 (de) * 1995-10-28 1999-08-15 Braun Melsungen Ag Lokalanästhetika und/oder zentralanalgetika enthaltende pharmazeutische zusammensetzungen
GB9721746D0 (en) * 1997-10-15 1997-12-10 Panos Therapeutics Limited Compositions
US6541021B1 (en) * 1999-03-18 2003-04-01 Durect Corporation Devices and methods for pain management
US6835194B2 (en) * 1999-03-18 2004-12-28 Durect Corporation Implantable devices and methods for treatment of pain by delivery of fentanyl and fentanyl congeners
US6455525B1 (en) * 1999-11-04 2002-09-24 Cephalon, Inc. Heterocyclic substituted pyrazolones
CA2446837C (en) * 2001-05-11 2012-01-03 Mitsubishi Pharma Corporation Stable high-concentration injection containing pyrazolone derivative
RU2315037C2 (ru) * 2002-01-25 2008-01-20 Тереванс, Инк. Замещенные эфиры фенилуксусной кислоты в качестве короткодействующих седативных снотворных агентов для кратковременной анестезии и создания седативного эффекта, промежуточное соединение, фармацевтическая композиция и применение
JP2004043479A (ja) * 2002-07-11 2004-02-12 Taiho Yakuhin Kogyo Kk 経鼻吸収用組成物
UA80447C2 (en) * 2002-10-08 2007-09-25 Methods for treating pain by administering nerve growth factor antagonist and opioid analgesic
JP4584713B2 (ja) * 2002-10-08 2010-11-24 ライナット ニューロサイエンス コーポレイション 神経成長因子アンタゴニストを投与することによって術後疼痛を処置するための方法および神経成長因子アンタゴニストを含有する組成物
US7648982B2 (en) * 2003-02-28 2010-01-19 Ym Biosciences Inc. Opioid delivery system
JP2004275852A (ja) * 2003-03-14 2004-10-07 Mitsubishi Heavy Ind Ltd 排煙脱硝触媒及びその製造方法
WO2005112926A1 (en) * 2004-05-17 2005-12-01 Pharmacofore, Inc. Compositions and methods for treating or preventing pain
DE102004025357B4 (de) * 2004-05-19 2007-03-29 Beiersdorf Ag Emulsionskonzentrat mit wasserlöslichen und öllöslichen Polymeren und kosmetische Zubereitung enthaltend Emulsionskonzentrat sowie ein Verfahren zu dessen Herstellung und dessen Verwendung
US7871632B2 (en) * 2004-07-12 2011-01-18 Adventrx Pharmaceuticals, Inc. Compositions for delivering highly water soluble drugs
US20060189682A1 (en) * 2005-02-02 2006-08-24 Payne Joseph E Water soluble prodrugs of COX-2 inhibitors
CN101137395B (zh) * 2005-03-14 2012-10-31 株式会社大塚制药工场 含有水难溶性药物的医药组合物
WO2006115690A2 (en) * 2005-04-22 2006-11-02 Novacardia, Inc. Production of emulsions for intravenous injection of water-insoluble pharmaceutical compositions
US8158152B2 (en) * 2005-11-18 2012-04-17 Scidose Llc Lyophilization process and products obtained thereby
US8252328B2 (en) * 2006-01-06 2012-08-28 Acelrx Pharmaceuticals, Inc. Bioadhesive drug formulations for oral transmucosal delivery
MX374396B (es) * 2006-01-25 2025-03-06 Insys Therapeutics Inc Rocio de fentanilo sublingual.
US20090286832A1 (en) * 2008-05-15 2009-11-19 Kiichiro Nabeta Narcotic emulsion formulations for treatment of surgical pain
KR101564058B1 (ko) * 2009-02-26 2015-10-29 테이코쿠 팔마 유에스에이, 인코포레이티드 암 통증 치료용 마취 유상액 제제

Also Published As

Publication number Publication date
EA201000991A1 (ru) 2011-06-30
AR071779A1 (es) 2010-07-14
CN101938963A (zh) 2011-01-05
US20090286832A1 (en) 2009-11-19
TW201406403A (zh) 2014-02-16
WO2009140059A2 (en) 2009-11-19
IL209145A0 (en) 2011-01-31
JP5889364B2 (ja) 2016-03-22
AU2009246713A1 (en) 2009-11-19
NZ586461A (en) 2012-07-27
KR101361479B1 (ko) 2014-02-12
JP2011520883A (ja) 2011-07-21
JP5689053B2 (ja) 2015-03-25
WO2009140059A3 (en) 2010-01-07
TWI413531B (zh) 2013-11-01
JP2014205681A (ja) 2014-10-30
CA2710546A1 (en) 2009-11-19
TW201006508A (en) 2010-02-16
ZA201004392B (en) 2011-06-29
EP2276440A2 (en) 2011-01-26
EP2276440A4 (en) 2011-06-29
AU2009246713B2 (en) 2012-10-25
MX2010007698A (es) 2010-11-22
KR20100126270A (ko) 2010-12-01

Similar Documents

Publication Publication Date Title
BR112012006891A2 (pt) formulação de hydrogel compreendendo uma solução aquosa com potencial oxidativo redutivo
BRPI0925036B8 (pt) uso de trans-t-butil ciclo-hexanol, composição cosmética, medicamento, seus usos e processos para tratar irritação na pele
MX385305B (es) Composiciones de ribósido de nicotinamida para uso tópico en el tratamiento de afecciones de la piel.
MX2010002392A (es) Composiciones de brimonidina mejoradas para tratar eritema.
MY160894A (en) Oligosaccharide composition for treating skin diseases
BR112012031163A2 (pt) métodos de terapia combinada para tratamento de doenças proliferativas
BRPI1009842B8 (pt) uso de agonista de tlr9 e agonista de tlr2/6 na preparação de uma composição farmacêutica para tratamento, inibição ou atenuação de uma infecção microbiana, bem como composição farmaceuticamente aceitável compreendendo os referidos agonistas
BR112012010058A2 (pt) aplicador tópico para um agente paralítico e método para aplicação do agente
NI200800169A (es) Uso de derivados de sulfamidas heterocíclicas benzo-fusionadas para el tratamiento del dolor
PE20091363A1 (es) Gel de quitosano y proceso de obtencion
ECSP13013087A (es) Compuestos para el tratamiento de la adicción
BRPI0911031B8 (pt) compostos de piperidina ligada do tipo quinoxalina substituídos e os usos destes
BR112014015482A8 (pt) compostos carbamato de fenila para uso no alívio ou tratamento de dor e dor neuropática
MX353096B (es) Metodos para tratar el deterioro cognitivo leve (mci) y trastornos relacionados.
BRPI0918313A2 (pt) Agente antiperspirante multicomponente, processo para tratar a perspiração humana, uso de um agente multicomponente e dispositivo com múltiplos compartimentos ou kit
BRPI0919020A2 (pt) Uso de células de linhagem monocitária enriquecidas para tratar isquemia e para tratar angina pectoris
BRPI0907970A8 (pt) composição para tratamento dos cabelos ou pelos e método para aumentar o diâmetro dos cabelos ou pelos
BRPI1010861A8 (pt) métodos para tratamento de dor, inflamação ou osteoartrite, pacote e formulação farmacêutica
BRPI0800876A2 (pt) composiÇço para aplicaÇço tàpica em forma de emulsço de Água-em-àleo, usos cosmÉticos de uma composiÇço e processo cosmÉtico de tratamento da pele seca
BR112013007343A2 (pt) métodos para tratar eritema associado com rosácea e para tratar telangiectasia associada com rosácea, e, composição tópica
MX2024000828A (es) Formulaciones de parasiticida de isoxazolina y metodos para el tratamiento de la blefaritis.
BRPI0907224A2 (pt) formulações narcórticas em emulsão para tratamento de dor cirúrgica
CO2022011388A2 (es) Inhibidores heterocíclicos de pad4
RU2013132566A (ru) Терапевтическое средство от грыжи межпозвоночного диска
MX394384B (es) Formulacion para analogos anticolinergicos blandos.

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 6A, 7A, 8A, 9A E 10A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2513 DE 06-03-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

B350 Update of information on the portal [chapter 15.35 patent gazette]