AR071779A1 - Formulaciones de emulsion narcotica para el tratamiento del dolor quirurgico - Google Patents
Formulaciones de emulsion narcotica para el tratamiento del dolor quirurgicoInfo
- Publication number
- AR071779A1 AR071779A1 ARP090101725A ARP090101725A AR071779A1 AR 071779 A1 AR071779 A1 AR 071779A1 AR P090101725 A ARP090101725 A AR P090101725A AR P090101725 A ARP090101725 A AR P090101725A AR 071779 A1 AR071779 A1 AR 071779A1
- Authority
- AR
- Argentina
- Prior art keywords
- emulsion formulations
- surgical pain
- narcotic
- subject
- emulsion
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4468—Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Dispersion Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Rheumatology (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Se proporcionan metodos y composiciones para tratar en un sujeto el dolor posquirurgico. En los metodos se trata en un sujeto el dolor posquirurgico mediante la administracion al sujeto de una cantidad eficaz de una formulacion de emulsion narcotica, por ej., una emulsion de fentanilo. En ciertas formas de realizacion, las formulaciones de emulsion incluyen un agente activo narcotico, aceite, agua y un tensioactivo. Tambien se proporcionan metodos para realizar las formulaciones de emulsion como as¡ tambien kits que incluyen las formulaciones de emulsion.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5357108P | 2008-05-15 | 2008-05-15 | |
US12/424,382 US20090286832A1 (en) | 2008-05-15 | 2009-04-15 | Narcotic emulsion formulations for treatment of surgical pain |
Publications (1)
Publication Number | Publication Date |
---|---|
AR071779A1 true AR071779A1 (es) | 2010-07-14 |
Family
ID=41316744
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP090101725A AR071779A1 (es) | 2008-05-15 | 2009-05-13 | Formulaciones de emulsion narcotica para el tratamiento del dolor quirurgico |
Country Status (16)
Country | Link |
---|---|
US (1) | US20090286832A1 (es) |
EP (1) | EP2276440A4 (es) |
JP (2) | JP5689053B2 (es) |
KR (1) | KR101361479B1 (es) |
CN (1) | CN101938963A (es) |
AR (1) | AR071779A1 (es) |
AU (1) | AU2009246713B2 (es) |
BR (1) | BRPI0907224A2 (es) |
CA (1) | CA2710546A1 (es) |
EA (1) | EA201000991A1 (es) |
IL (1) | IL209145A0 (es) |
MX (1) | MX2010007698A (es) |
NZ (1) | NZ586461A (es) |
TW (2) | TW201406403A (es) |
WO (1) | WO2009140059A2 (es) |
ZA (1) | ZA201004392B (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20090286832A1 (en) * | 2008-05-15 | 2009-11-19 | Kiichiro Nabeta | Narcotic emulsion formulations for treatment of surgical pain |
KR101564058B1 (ko) * | 2009-02-26 | 2015-10-29 | 테이코쿠 팔마 유에스에이, 인코포레이티드 | 암 통증 치료용 마취 유상액 제제 |
JP6081240B2 (ja) * | 2013-03-13 | 2017-02-15 | テルモ株式会社 | レミフェンタニル注射液剤 |
EP3192509B1 (en) | 2014-09-12 | 2021-03-31 | Terumo Kabushiki Kaisha | Remifentanil injection |
US20230248719A1 (en) * | 2020-06-08 | 2023-08-10 | Harm Reduction Therapeutics, Inc. | Sterilized formulations |
Family Cites Families (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0647533B2 (ja) * | 1984-08-10 | 1994-06-22 | 裕 水島 | 4−ビフエニリル酢酸系化合物含有脂肪乳剤 |
US4816247A (en) * | 1985-09-11 | 1989-03-28 | American Cyanamid Company | Emulsion compositions for administration of sparingly water soluble ionizable hydrophobic drugs |
DE69511418T2 (de) * | 1995-10-28 | 2000-03-30 | Braun Melsungen Ag | Lokalanästhetika und/oder Zentralanalgetika enthaltende pharmazeutische Zusammensetzungen |
GB9721746D0 (en) | 1997-10-15 | 1997-12-10 | Panos Therapeutics Limited | Compositions |
US6541021B1 (en) * | 1999-03-18 | 2003-04-01 | Durect Corporation | Devices and methods for pain management |
US6835194B2 (en) * | 1999-03-18 | 2004-12-28 | Durect Corporation | Implantable devices and methods for treatment of pain by delivery of fentanyl and fentanyl congeners |
US6455525B1 (en) * | 1999-11-04 | 2002-09-24 | Cephalon, Inc. | Heterocyclic substituted pyrazolones |
WO2002092082A1 (en) * | 2001-05-11 | 2002-11-21 | Mitsubishi Pharma Corporation | Stable high-concentration injection containing pyrazolone derivative |
IL162862A0 (en) * | 2002-01-25 | 2005-11-20 | Theravance Inc | Short-acting sedative hypnotic agents for anesthesia and sedation |
JP2004043479A (ja) * | 2002-07-11 | 2004-02-12 | Taiho Yakuhin Kogyo Kk | 経鼻吸収用組成物 |
WO2004032870A2 (en) * | 2002-10-08 | 2004-04-22 | Rinat Neuroscience Corp. | Methods for treating post-surgical pain by admisnistering a nerve growth factor antagonist and compositions containing the same |
UA80447C2 (en) * | 2002-10-08 | 2007-09-25 | Methods for treating pain by administering nerve growth factor antagonist and opioid analgesic | |
US7648982B2 (en) * | 2003-02-28 | 2010-01-19 | Ym Biosciences Inc. | Opioid delivery system |
JP2004275852A (ja) * | 2003-03-14 | 2004-10-07 | Mitsubishi Heavy Ind Ltd | 排煙脱硝触媒及びその製造方法 |
WO2005112926A1 (en) * | 2004-05-17 | 2005-12-01 | Pharmacofore, Inc. | Compositions and methods for treating or preventing pain |
DE102004025357B4 (de) * | 2004-05-19 | 2007-03-29 | Beiersdorf Ag | Emulsionskonzentrat mit wasserlöslichen und öllöslichen Polymeren und kosmetische Zubereitung enthaltend Emulsionskonzentrat sowie ein Verfahren zu dessen Herstellung und dessen Verwendung |
US7871632B2 (en) * | 2004-07-12 | 2011-01-18 | Adventrx Pharmaceuticals, Inc. | Compositions for delivering highly water soluble drugs |
US20060189682A1 (en) * | 2005-02-02 | 2006-08-24 | Payne Joseph E | Water soluble prodrugs of COX-2 inhibitors |
JP4929158B2 (ja) * | 2005-03-14 | 2012-05-09 | 株式会社大塚製薬工場 | 難水溶性薬物を含有する医薬組成物 |
CA2608111A1 (en) * | 2005-04-22 | 2006-11-02 | Novacardia, Inc. | Production of emulsions for intravenous injection of water-insoluble pharmaceutical compositions |
US8158152B2 (en) * | 2005-11-18 | 2012-04-17 | Scidose Llc | Lyophilization process and products obtained thereby |
US8252328B2 (en) * | 2006-01-06 | 2012-08-28 | Acelrx Pharmaceuticals, Inc. | Bioadhesive drug formulations for oral transmucosal delivery |
DK1976521T3 (en) * | 2006-01-25 | 2015-04-27 | Insys Therapeutics Inc | Sublingual fentanyl spray |
US20090286832A1 (en) * | 2008-05-15 | 2009-11-19 | Kiichiro Nabeta | Narcotic emulsion formulations for treatment of surgical pain |
KR101564058B1 (ko) * | 2009-02-26 | 2015-10-29 | 테이코쿠 팔마 유에스에이, 인코포레이티드 | 암 통증 치료용 마취 유상액 제제 |
-
2009
- 2009-04-15 US US12/424,382 patent/US20090286832A1/en not_active Abandoned
- 2009-04-28 MX MX2010007698A patent/MX2010007698A/es not_active Application Discontinuation
- 2009-04-28 EA EA201000991A patent/EA201000991A1/ru unknown
- 2009-04-28 EP EP09747145A patent/EP2276440A4/en not_active Withdrawn
- 2009-04-28 NZ NZ586461A patent/NZ586461A/en not_active IP Right Cessation
- 2009-04-28 CA CA2710546A patent/CA2710546A1/en not_active Abandoned
- 2009-04-28 JP JP2011509539A patent/JP5689053B2/ja not_active Expired - Fee Related
- 2009-04-28 BR BRPI0907224-1A patent/BRPI0907224A2/pt not_active IP Right Cessation
- 2009-04-28 KR KR1020107015502A patent/KR101361479B1/ko active IP Right Grant
- 2009-04-28 WO PCT/US2009/041991 patent/WO2009140059A2/en active Application Filing
- 2009-04-28 AU AU2009246713A patent/AU2009246713B2/en not_active Ceased
- 2009-04-28 CN CN2009801021888A patent/CN101938963A/zh active Pending
- 2009-05-13 AR ARP090101725A patent/AR071779A1/es not_active Application Discontinuation
- 2009-05-14 TW TW102123473A patent/TW201406403A/zh unknown
- 2009-05-14 TW TW098115948A patent/TWI413531B/zh not_active IP Right Cessation
-
2010
- 2010-06-22 ZA ZA2010/04392A patent/ZA201004392B/en unknown
- 2010-11-04 IL IL209145A patent/IL209145A0/en unknown
-
2014
- 2014-05-23 JP JP2014107385A patent/JP5889364B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EA201000991A1 (ru) | 2011-06-30 |
KR101361479B1 (ko) | 2014-02-12 |
TW201006508A (en) | 2010-02-16 |
EP2276440A4 (en) | 2011-06-29 |
JP2011520883A (ja) | 2011-07-21 |
CA2710546A1 (en) | 2009-11-19 |
MX2010007698A (es) | 2010-11-22 |
KR20100126270A (ko) | 2010-12-01 |
JP2014205681A (ja) | 2014-10-30 |
WO2009140059A2 (en) | 2009-11-19 |
NZ586461A (en) | 2012-07-27 |
IL209145A0 (en) | 2011-01-31 |
JP5889364B2 (ja) | 2016-03-22 |
TWI413531B (zh) | 2013-11-01 |
JP5689053B2 (ja) | 2015-03-25 |
AU2009246713B2 (en) | 2012-10-25 |
ZA201004392B (en) | 2011-06-29 |
EP2276440A2 (en) | 2011-01-26 |
WO2009140059A3 (en) | 2010-01-07 |
TW201406403A (zh) | 2014-02-16 |
CN101938963A (zh) | 2011-01-05 |
BRPI0907224A2 (pt) | 2019-02-26 |
AU2009246713A1 (en) | 2009-11-19 |
US20090286832A1 (en) | 2009-11-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |