MX394384B - Formulacion para analogos anticolinergicos blandos. - Google Patents

Formulacion para analogos anticolinergicos blandos.

Info

Publication number
MX394384B
MX394384B MX2019000812A MX2019000812A MX394384B MX 394384 B MX394384 B MX 394384B MX 2019000812 A MX2019000812 A MX 2019000812A MX 2019000812 A MX2019000812 A MX 2019000812A MX 394384 B MX394384 B MX 394384B
Authority
MX
Mexico
Prior art keywords
analogues
formulation
hyperhidrosis
soft anticholinergic
soft
Prior art date
Application number
MX2019000812A
Other languages
English (en)
Other versions
MX2019000812A (es
Inventor
David Angulo
John J Koleng
Nicholas S Bodor
Original Assignee
Bodor Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bodor Laboratories Inc filed Critical Bodor Laboratories Inc
Publication of MX2019000812A publication Critical patent/MX2019000812A/es
Publication of MX394384B publication Critical patent/MX394384B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Las formulaciones tópicas que comprenden glicopirrolatos blandos son útiles para tratar afecciones de sudoración excesiva en sujetos, tales como humanos que sufren de hiperhidrosis. Preferiblemente, se proporciona al menos un agente anticolinérgico en una cantidad o concentración efectiva en una formulación anhidra que puede inhibir la transpiración excesiva que resulta de una afección tal como hiperhidrosis.
MX2019000812A 2016-07-21 2017-07-20 Formulacion para analogos anticolinergicos blandos. MX394384B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662365037P 2016-07-21 2016-07-21
PCT/US2017/043106 WO2018017852A1 (en) 2016-07-21 2017-07-20 Formulation for soft anticholinergic analogs

Publications (2)

Publication Number Publication Date
MX2019000812A MX2019000812A (es) 2019-06-20
MX394384B true MX394384B (es) 2025-03-24

Family

ID=60989819

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2019000812A MX394384B (es) 2016-07-21 2017-07-20 Formulacion para analogos anticolinergicos blandos.
MX2022009375A MX2022009375A (es) 2016-07-21 2019-01-18 Formulacion para analogos anticolinergicos blandos.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2022009375A MX2022009375A (es) 2016-07-21 2019-01-18 Formulacion para analogos anticolinergicos blandos.

Country Status (17)

Country Link
US (6) US11123325B2 (es)
EP (2) EP3487475B1 (es)
AU (3) AU2017298469B2 (es)
BR (1) BR112019001081B1 (es)
CA (1) CA3031361C (es)
DK (1) DK3487475T3 (es)
ES (1) ES2954308T3 (es)
FI (1) FI3487475T3 (es)
HU (1) HUE062905T2 (es)
IL (2) IL295009A (es)
MX (2) MX394384B (es)
PH (1) PH12019500142A1 (es)
PL (1) PL3487475T3 (es)
PT (1) PT3487475T (es)
TW (2) TWI767507B (es)
WO (1) WO2018017852A1 (es)
ZA (1) ZA201901060B (es)

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JP6513667B2 (ja) 2013-08-08 2019-05-15 ノヴァン，インコーポレイテッド 局所用組成物およびそれを使用する方法
US20150259283A1 (en) 2014-03-13 2015-09-17 Brickell Biotech, Inc. Formulation for soft anticholinergic analogs
US10322082B2 (en) 2014-07-11 2019-06-18 Novan, Inc. Topical antiviral compositions and methods of using the same
CN119033770A (zh) 2015-07-21 2024-11-29 博多尔实验仪器公司 软性抗胆碱能药类似物的制剂
TWI767507B (zh) * 2016-07-21 2022-06-11 美商波德實驗股份有限公司 軟性抗膽鹼類似物之製劑
US20210290536A1 (en) * 2018-07-24 2021-09-23 Dr. August Wolff Gmbh & Co. Kg Arzneimittel Topical emulsion of an anticholinergic compound
TW202146009A (zh) * 2020-03-03 2021-12-16 日商科研製藥股份有限公司 含有溴化索非羅銨的醫藥
JPWO2021177257A1 (es) 2020-03-03 2021-09-10
WO2025193694A1 (en) * 2024-03-12 2025-09-18 Egaceutical Corporation Compositions and methods for resetting biology of cells

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US242A (en) 1837-06-22 moseley
DK149832C (da) 1981-07-17 1987-05-18 Riemann Claus Antiperspirantpraeparat bestaaende af to komponenter
US5292530A (en) 1991-06-02 1994-03-08 Helene Curtis, Inc. Stable anhydrous topically-active composition and suspending agent therefor
US5232689A (en) 1990-12-21 1993-08-03 Dow Corning Corporation Translucent antiperspirant compositions
GB2280111B (en) * 1993-07-16 1997-05-07 Union Camp Corp Clear gel antiperpirant compositions
US5895644A (en) 1997-11-20 1999-04-20 Colgate-Palmolive Company Clear antiperspirant stick with dibenzylidene sorbitol and guar and process of making same
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US6319491B1 (en) * 2000-04-11 2001-11-20 Michael B. Whipple Anti-sweat lotion
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BR0308051A (pt) 2003-12-15 2005-09-06 Natura Cosmeticos Sa Composição base para preparação de formulações multifuncionais para o cuidado e proteção da pele e cabelo
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GB0428418D0 (en) 2004-12-24 2005-02-02 Novartis Ag Organic compounds
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BRPI0519481A2 (pt) 2004-12-27 2009-02-03 Beiersdorf Ag glicopirrolato em preparaÇÕes cosmÉticas
JP2007058971A (ja) 2005-08-24 2007-03-08 Alpine Electronics Inc 情報再生装置
US7399861B2 (en) * 2005-11-10 2008-07-15 Bodor Nicholas S Soft anticholinergic esters
AU2006315657B2 (en) 2005-11-10 2011-12-01 Shell Internationale Research Maatschappij B.V. Soft anticholinergic esters
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JP5371235B2 (ja) 2006-12-06 2013-12-18 ロート製薬株式会社 皮膚外用剤
US10265265B2 (en) 2007-03-15 2019-04-23 Drug Delivery Solutions Limited Topical composition
AU2008314628B2 (en) 2007-10-18 2014-03-06 Rose U Topical glycopyrrolate formulations
AU2014227923B2 (en) * 2013-03-15 2019-02-14 Bodor Laboratories, Inc. Method of dosing and use of soft anticholinergic esters
CN105555269A (zh) 2013-07-30 2016-05-04 葛兰素史密斯克莱知识产权发展有限公司 用于治疗过度出汗的局部组合物及其使用方法
US20150259283A1 (en) 2014-03-13 2015-09-17 Brickell Biotech, Inc. Formulation for soft anticholinergic analogs
JP2017507959A (ja) * 2014-03-13 2017-03-23 ボドール ラボラトリーズ， インコーポレイテッド 選択された抗コリン作動性両性イオンの使用
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TWI767507B (zh) * 2016-07-21 2022-06-11 美商波德實驗股份有限公司 軟性抗膽鹼類似物之製劑

Also Published As

Publication number Publication date
US10959983B2 (en) 2021-03-30
AU2017298469A1 (en) 2019-02-21
PL3487475T3 (pl) 2023-10-30
US11123325B2 (en) 2021-09-21
TW202131913A (zh) 2021-09-01
EP3487475A1 (en) 2019-05-29
US20250041268A1 (en) 2025-02-06
EP4218725A1 (en) 2023-08-02
IL264311A (en) 2019-02-28
US20210077459A1 (en) 2021-03-18
TWI767507B (zh) 2022-06-11
US20180021300A1 (en) 2018-01-25
TW201803561A (zh) 2018-02-01
EP3487475B1 (en) 2023-06-07
MX2022009375A (es) 2022-09-02
AU2023202689A1 (en) 2023-05-18
US20200101044A1 (en) 2020-04-02
US11052067B2 (en) 2021-07-06
US20190247362A1 (en) 2019-08-15
TWI719046B (zh) 2021-02-21
IL264311B (en) 2022-08-01
ZA201901060B (en) 2022-04-28
AU2024227714A1 (en) 2024-11-21
AU2023202689B2 (en) 2024-08-01
BR112019001081B1 (pt) 2022-06-14
AU2017298469B2 (en) 2023-02-02
MX2019000812A (es) 2019-06-20
IL295009A (en) 2022-09-01
DK3487475T3 (da) 2023-09-11
WO2018017852A1 (en) 2018-01-25
HUE062905T2 (hu) 2023-12-28
FI3487475T3 (fi) 2023-08-25
US20220000839A1 (en) 2022-01-06
PT3487475T (pt) 2023-09-05
ES2954308T3 (es) 2023-11-21
BR112019001081A2 (pt) 2019-04-30
US12156865B2 (en) 2024-12-03
CA3031361A1 (en) 2018-01-25
PH12019500142A1 (en) 2019-07-29
CA3031361C (en) 2024-02-27
EP3487475A4 (en) 2020-03-04

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