BRPI0906174A2 - Processo para preparar o enantiômero s ou r de um composto, uso de um catalisador quiral, ru(ligante quiral) (acac)2, ru (ligante quiral) (cf3coo)2, sistema catalítico e rh (norbornadieno)2 pf6 (diph-meo- biphep) - Google Patents

Processo para preparar o enantiômero s ou r de um composto, uso de um catalisador quiral, ru(ligante quiral) (acac)2, ru (ligante quiral) (cf3coo)2, sistema catalítico e rh (norbornadieno)2 pf6 (diph-meo- biphep)

Info

Publication number
BRPI0906174A2
BRPI0906174A2 BRPI0906174-6A BRPI0906174A BRPI0906174A2 BR PI0906174 A2 BRPI0906174 A2 BR PI0906174A2 BR PI0906174 A BRPI0906174 A BR PI0906174A BR PI0906174 A2 BRPI0906174 A2 BR PI0906174A2
Authority
BR
Brazil
Prior art keywords
chiral
binder
biphep
cf3coo
diph
Prior art date
Application number
BRPI0906174-6A
Other languages
English (en)
Portuguese (pt)
Inventor
David Alexander Learmonth
Alexander Beliaev
Wenge Li
Original Assignee
Bial Portela & Ca Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bial Portela & Ca Sa filed Critical Bial Portela & Ca Sa
Publication of BRPI0906174A2 publication Critical patent/BRPI0906174A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0046—Ruthenium compounds
    • C07F15/0053—Ruthenium compounds without a metal-carbon linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0073—Rhodium compounds
    • C07F15/008—Rhodium compounds without a metal-carbon linkage

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pyrane Compounds (AREA)
  • Catalysts (AREA)
BRPI0906174-6A 2008-03-19 2009-09-17 Processo para preparar o enantiômero s ou r de um composto, uso de um catalisador quiral, ru(ligante quiral) (acac)2, ru (ligante quiral) (cf3coo)2, sistema catalítico e rh (norbornadieno)2 pf6 (diph-meo- biphep) BRPI0906174A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3778408P 2008-03-19 2008-03-19
PCT/PT2009/000014 WO2009116883A2 (en) 2008-03-19 2009-03-17 Catalytic asymetric hydrogenation

Publications (1)

Publication Number Publication Date
BRPI0906174A2 true BRPI0906174A2 (pt) 2015-06-30

Family

ID=40786839

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0906174-6A BRPI0906174A2 (pt) 2008-03-19 2009-09-17 Processo para preparar o enantiômero s ou r de um composto, uso de um catalisador quiral, ru(ligante quiral) (acac)2, ru (ligante quiral) (cf3coo)2, sistema catalítico e rh (norbornadieno)2 pf6 (diph-meo- biphep)

Country Status (14)

Country Link
US (1) US8957222B2 (enExample)
EP (1) EP2297042B1 (enExample)
JP (1) JP2011515390A (enExample)
KR (1) KR20110015412A (enExample)
CN (1) CN102056846A (enExample)
AR (1) AR070935A1 (enExample)
AU (1) AU2009226222A1 (enExample)
BR (1) BRPI0906174A2 (enExample)
CA (1) CA2716694A1 (enExample)
ES (1) ES2429120T3 (enExample)
MX (1) MX2010010062A (enExample)
PT (1) PT2297042E (enExample)
RU (1) RU2010142900A (enExample)
WO (1) WO2009116883A2 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011515390A (ja) 2008-03-19 2011-05-19 バイアル−ポルテラ アンド シーエー,エス.エー. 触媒的不斉水素化
WO2010083283A2 (en) * 2009-01-15 2010-07-22 Incyte Corporation Processes for preparing jak inhibitors and related intermediate compounds
CN106977486B (zh) * 2017-05-25 2019-09-24 南方科技大学 一种手性二氢黄酮类化合物及其衍生物的制备方法和应用
CN110841720B (zh) * 2019-11-29 2022-11-18 河南师范大学 石墨烯吸附多组分手性催化剂及其在不对称氢化中的应用
CN118206463A (zh) * 2022-12-15 2024-06-18 中国科学院大连化学物理研究所 一种酰胺导向萘类化合物不对称氢化合成四氢萘类化合物的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5144050A (en) 1991-10-01 1992-09-01 Monsanto Company Ruthenium(II)-BINAP diketonate complexes
HK1046250A1 (zh) * 1999-09-20 2003-01-03 The Penn State Research Foundation 手性磷化氢配体、其过渡金属复合物,及二者在不对称反应中的应用
WO2002040491A1 (en) * 2000-11-17 2002-05-23 The Penn State Research Foundation Ortho substituted chiral phosphines and phosphinites and their use in asymmetric catayltic reactions
US7125904B2 (en) * 2002-10-11 2006-10-24 Portela & C.A., S.A. Peripherally-selective inhibitors of dopamine-β-hydroxylase and method of their preparation
BRPI0718351A2 (pt) * 2006-12-12 2019-09-24 Bial Portela & Ca Sa "processo para a preparação do enantiômero s ou r, processo para formar um composto r ou s, uso de um catalisador quiral, composto, sal tartrato do enantiômero s ou r de um composto, complexo de metal de transição e catalisador"
JP2011515390A (ja) 2008-03-19 2011-05-19 バイアル−ポルテラ アンド シーエー,エス.エー. 触媒的不斉水素化

Also Published As

Publication number Publication date
US20110112303A1 (en) 2011-05-12
EP2297042B1 (en) 2013-07-10
CA2716694A1 (en) 2009-09-24
PT2297042E (pt) 2013-10-10
KR20110015412A (ko) 2011-02-15
MX2010010062A (es) 2010-09-30
ES2429120T3 (es) 2013-11-13
RU2010142900A (ru) 2012-04-27
WO2009116883A3 (en) 2010-04-01
WO2009116883A8 (en) 2009-12-10
JP2011515390A (ja) 2011-05-19
EP2297042A2 (en) 2011-03-23
WO2009116883A2 (en) 2009-09-24
AR070935A1 (es) 2010-05-12
CN102056846A (zh) 2011-05-11
US8957222B2 (en) 2015-02-17
AU2009226222A1 (en) 2009-09-24

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 4A, 5A E 6A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.