BRPI0819854A2 - Enumeração e caracterização automatizada de células de melanoma circulantes no sangue - Google Patents

Enumeração e caracterização automatizada de células de melanoma circulantes no sangue

Info

Publication number
BRPI0819854A2
BRPI0819854A2 BRPI0819854-3A BRPI0819854A BRPI0819854A2 BR PI0819854 A2 BRPI0819854 A2 BR PI0819854A2 BR PI0819854 A BRPI0819854 A BR PI0819854A BR PI0819854 A2 BRPI0819854 A2 BR PI0819854A2
Authority
BR
Brazil
Prior art keywords
characterization
melanoma cells
blood circulating
circulating melanoma
automated enumeration
Prior art date
Application number
BRPI0819854-3A
Other languages
English (en)
Inventor
Mark Carle Connelly
Galla Chandra Rao
Leon Wmm Terstappen
Original Assignee
Veridex Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Veridex Llc filed Critical Veridex Llc
Publication of BRPI0819854A2 publication Critical patent/BRPI0819854A2/pt
Publication of BRPI0819854B1 publication Critical patent/BRPI0819854B1/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/5743—Specifically defined cancers of skin, e.g. melanoma
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57488—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds identifable in body fluids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70589—CD45
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70596—Molecules with a "CD"-designation not provided for elsewhere in G01N2333/705

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • Medicinal Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
BRPI0819854-3A 2007-11-27 2008-10-20 Método para isolar, enriquecer e analisar células de melanoma circulantes em uma amostra de sangue BRPI0819854B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US434507P 2007-11-27 2007-11-27
US61/004,345 2007-11-27
PCT/US2008/080436 WO2009070392A1 (en) 2007-11-27 2008-10-20 Automated enumeration and characterization of circulating melanoma cells in blood

Publications (2)

Publication Number Publication Date
BRPI0819854A2 true BRPI0819854A2 (pt) 2015-06-16
BRPI0819854B1 BRPI0819854B1 (pt) 2019-06-04

Family

ID=40670042

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0819854-3A BRPI0819854B1 (pt) 2007-11-27 2008-10-20 Método para isolar, enriquecer e analisar células de melanoma circulantes em uma amostra de sangue

Country Status (12)

Country Link
US (1) US20090136946A1 (pt)
EP (1) EP2225563B1 (pt)
JP (1) JP5479355B2 (pt)
KR (1) KR101604649B1 (pt)
CN (1) CN101878429B (pt)
BR (1) BRPI0819854B1 (pt)
CA (1) CA2706442C (pt)
DK (1) DK2225563T3 (pt)
HK (2) HK1148068A1 (pt)
IL (1) IL205864A (pt)
MX (1) MX2010005811A (pt)
WO (1) WO2009070392A1 (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2359164A4 (en) 2008-12-10 2012-05-30 Abqmr Inc CORE MAGNETIC RESONANCE DEVICE, METHOD AND ASSOCIATED TECHNOLOGY
US20120178645A1 (en) * 2009-06-26 2012-07-12 Johannes Albert Foekens Identifying circulating tumor cells (ctcs) using cd146 in breast cancer patients
US20110262989A1 (en) 2010-04-21 2011-10-27 Nanomr, Inc. Isolating a target analyte from a body fluid
US9476812B2 (en) 2010-04-21 2016-10-25 Dna Electronics, Inc. Methods for isolating a target analyte from a heterogeneous sample
US9428547B2 (en) 2010-04-21 2016-08-30 Dna Electronics, Inc. Compositions for isolating a target analyte from a heterogeneous sample
US8841104B2 (en) 2010-04-21 2014-09-23 Nanomr, Inc. Methods for isolating a target analyte from a heterogeneous sample
TWI539158B (zh) * 2010-06-08 2016-06-21 維里德克斯有限責任公司 使用血液中之循環黑色素瘤細胞預測黑色素瘤病患之臨床結果的方法。
EP2734307B1 (en) * 2011-07-21 2020-03-25 Menarini Silicon Biosystems S.p.A. Assay to capture and detect circulating multiple myeloma cells from blood
US9804069B2 (en) 2012-12-19 2017-10-31 Dnae Group Holdings Limited Methods for degrading nucleic acid
US9551704B2 (en) 2012-12-19 2017-01-24 Dna Electronics, Inc. Target detection
US9434940B2 (en) 2012-12-19 2016-09-06 Dna Electronics, Inc. Methods for universal target capture
US10000557B2 (en) 2012-12-19 2018-06-19 Dnae Group Holdings Limited Methods for raising antibodies
US9995742B2 (en) 2012-12-19 2018-06-12 Dnae Group Holdings Limited Sample entry
US9599610B2 (en) 2012-12-19 2017-03-21 Dnae Group Holdings Limited Target capture system
JP6563379B2 (ja) 2013-03-15 2019-08-21 ジャンセン ダイアグノスティックス，エルエルシー 白血球の枯渇による循環腫瘍細胞の濃縮
CN103472227A (zh) * 2013-09-18 2013-12-25 上海卫恒医疗器械有限公司 一种循环肿瘤细胞检测试剂盒、配套仪器及应用
AU2016267146B2 (en) * 2015-05-26 2021-09-02 Creatv Microtech Inc. Use of circulating tumor cell mitotic index in cancer stratification and diagnostics

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5801005A (en) 1993-03-17 1998-09-01 University Of Washington Immune reactivity to HER-2/neu protein for diagnosis of malignancies in which the HER-2/neu oncogene is associated
DE19736691A1 (de) * 1997-08-22 1999-02-25 Michael Prof Dr Med Giesing Verfahren zur Charakterisierung und Identifizierung disseminierter und metastasierter Krebszellen
US6558662B2 (en) * 1997-11-14 2003-05-06 The General Hospital Corporation Treatment of hematologic disorders
US20010018192A1 (en) * 1998-02-12 2001-08-30 Terstappen Leon W.M.M. Labeled cells for use as an internal functional control in rare cell detection assays
US6365362B1 (en) * 1998-02-12 2002-04-02 Immunivest Corporation Methods and reagents for the rapid and efficient isolation of circulating cancer cells
US7029652B2 (en) * 1998-09-16 2006-04-18 The Regents Of The University Of California Method of treating tumors
US6551843B1 (en) * 1999-01-29 2003-04-22 Immunivest Corporation Methods for enhancing binding interactions between members of specific binding pairs
US6222096B1 (en) * 1999-03-01 2001-04-24 Stine Biotechnology Promoter and construct for plant transformation
US6623982B1 (en) * 1999-07-12 2003-09-23 Immunivest Corporation Increased separation efficiency via controlled aggregation of magnetic nanoparticles
WO2001009189A2 (en) * 1999-07-28 2001-02-08 Genentech, Inc. Compositions and methods for the treatment of tumors
WO2001073133A1 (en) * 2000-03-27 2001-10-04 Thomas Jefferson University Compositions and methods for identifying and targeting cancer cells
EP1365790A4 (en) * 2000-10-13 2006-05-31 Univ Monash DIAGNOSTIC INDICATOR FOR THYMUS FUNCTION
US7223596B2 (en) * 2003-09-05 2007-05-29 Wisconsin Alumni Research Foundation Malignant endothelial cell line and uses thereof in models for angiogenesis
US20070037173A1 (en) * 2005-08-12 2007-02-15 Allard Jeffrey W Circulating tumor cells (CTC's): early assessment of time to progression, survival and response to therapy in metastatic cancer patients
WO2006130737A1 (en) * 2005-06-02 2006-12-07 Immunivest Corporation A method for assessing metastatic carcinomas from circulating endothelial cells and disseminated tumor cells

Also Published As

Publication number Publication date
EP2225563B1 (en) 2015-01-21
HK1148068A1 (en) 2011-08-26
HK1148348A1 (en) 2011-09-02
DK2225563T3 (en) 2015-02-09
EP2225563A4 (en) 2011-11-16
WO2009070392A1 (en) 2009-06-04
JP2011505012A (ja) 2011-02-17
CA2706442A1 (en) 2009-06-04
CA2706442C (en) 2017-07-11
CN101878429B (zh) 2015-05-20
CN101878429A (zh) 2010-11-03
US20090136946A1 (en) 2009-05-28
JP5479355B2 (ja) 2014-04-23
BRPI0819854B1 (pt) 2019-06-04
KR20100101109A (ko) 2010-09-16
IL205864A (en) 2016-12-29
KR101604649B1 (ko) 2016-03-18
EP2225563A1 (en) 2010-09-08
IL205864A0 (en) 2010-11-30
MX2010005811A (es) 2010-06-09

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 04/06/2019, OBSERVADAS AS CONDICOES LEGAIS. (CO) 10 (DEZ) ANOS CONTADOS A PARTIR DE 04/06/2019, OBSERVADAS AS CONDICOES LEGAIS

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 11A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2536 DE 13-08-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.