BRPI0813670A2 - Compostos para tratamento - Google Patents

Compostos para tratamento

Info

Publication number
BRPI0813670A2
BRPI0813670A2 BRPI0813670-0A2A BRPI0813670A BRPI0813670A2 BR PI0813670 A2 BRPI0813670 A2 BR PI0813670A2 BR PI0813670 A BRPI0813670 A BR PI0813670A BR PI0813670 A2 BRPI0813670 A2 BR PI0813670A2
Authority
BR
Brazil
Prior art keywords
treatment compounds
compounds
treatment
Prior art date
Application number
BRPI0813670-0A2A
Other languages
English (en)
Portuguese (pt)
Inventor
Claude Michel Wischik
Roger Todd Staff
Gernot Riedel
Elizabeth Anne Goatman
Dominic Venay Harbaran
Serena Deiana
Damon Jude Wischik
Alison Dorothy Murray
Original Assignee
Wista Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wista Lab Ltd filed Critical Wista Lab Ltd
Publication of BRPI0813670A2 publication Critical patent/BRPI0813670A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BRPI0813670-0A2A 2007-06-19 2008-06-17 Compostos para tratamento BRPI0813670A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94500607P 2007-06-19 2007-06-19
PCT/GB2008/002066 WO2008155533A2 (en) 2007-06-19 2008-06-17 Phenothiazine compounds for treating mild cognitive impairment

Publications (1)

Publication Number Publication Date
BRPI0813670A2 true BRPI0813670A2 (pt) 2014-12-30

Family

ID=39943003

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0813670-0A2A BRPI0813670A2 (pt) 2007-06-19 2008-06-17 Compostos para tratamento

Country Status (16)

Country Link
US (1) US9211294B2 (enExample)
EP (1) EP2167095B1 (enExample)
JP (1) JP5725605B2 (enExample)
CN (1) CN101820884B (enExample)
AU (1) AU2008265045B2 (enExample)
BR (1) BRPI0813670A2 (enExample)
CA (1) CA2690746C (enExample)
DK (1) DK2167095T3 (enExample)
ES (1) ES2739546T3 (enExample)
HR (1) HRP20191513T1 (enExample)
HU (1) HUE045460T2 (enExample)
MY (1) MY177001A (enExample)
PL (1) PL2167095T3 (enExample)
PT (1) PT2167095T (enExample)
SI (1) SI2167095T1 (enExample)
WO (1) WO2008155533A2 (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2007231124B2 (en) 2006-03-29 2013-02-21 TauRx Therapeutics Management Ltd 3,7-diamino-10H-phenothiazine salts and their use
EP2205245B1 (en) * 2007-10-03 2015-06-24 WisTa Laboratories Ltd. Therapeutic use of diaminophenothiazines
EP2585073B1 (en) 2010-04-30 2016-04-27 Prosetta Antiviral Inc. Antiviral compounds
AU2011358840B2 (en) * 2011-02-11 2017-05-04 TauRx Therapeutics Management Ltd Phenothiazine diaminium salts and their use
WO2012145567A1 (en) 2011-04-20 2012-10-26 Prosetta Antiviral Inc. Antiviral compounds
EP2951149B1 (en) * 2013-01-30 2018-10-10 Ecolab USA Inc. Hydrogen sulfide scavengers
US10304006B2 (en) * 2013-02-15 2019-05-28 The Charles Stark Draper Laboratory, Inc. Method for integrating and fusing heterogeneous data types to perform predictive analysis
US10472340B2 (en) * 2015-02-17 2019-11-12 Arizona Board Of Regents On Behalf Of Arizona State University Substituted phenothiazines as mitochondrial agents
KR20230058533A (ko) * 2016-07-25 2023-05-03 위스타 레보레이토리스 리미티드 디아미노페노티아진 (diaminophenothiazines)의 투여 및 투여량 (dosage)
GB201614834D0 (en) * 2016-09-01 2016-10-19 Wista Lab Ltd Treatment of dementia
DK4364801T3 (da) 2018-07-26 2025-12-22 Taurx Therapeutics Man Ltd Optimeret dosering af diaminophenothiaziner i populationer
MY209608A (en) * 2019-04-10 2025-07-24 Genting Taurx Diagnostic Centre Sdn Bhd Adaptive neurological testing method
GB201909454D0 (en) 2019-07-01 2019-08-14 Wista Lab Ltd Enhancers
GB201909493D0 (en) 2019-07-01 2019-08-14 Wista Lab Ltd Therapeutic interactions
GB201909506D0 (en) 2019-07-02 2019-08-14 Wista Lab Ltd Synaptopathies
AU2023279800A1 (en) 2022-05-31 2024-12-19 TauRx Therapeutics Management Ltd Treatment of neurodegenerative disorders utilising methylthioninium (mt)-containing compounds
WO2024184146A1 (en) 2023-03-03 2024-09-12 Wista Laboratories Ltd. Diaminophenothiazine for the treatment of microvascular brain disease disease

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9506197D0 (en) * 1995-03-27 1995-05-17 Hoffmann La Roche Inhibition of tau-tau association.
GB0017060D0 (en) * 2000-07-11 2000-08-30 Hunter Fleming Ltd Production, stabilisation and use of reduced forms of pharmaceutical compounds
GB0101049D0 (en) 2001-01-15 2001-02-28 Univ Aberdeen Materials and methods relating to protein aggregation in neurodegenerative disease
AU2004226876A1 (en) * 2003-04-03 2004-10-14 Prana Biotechnology Ltd Treatment of neurological conditions
JP5186212B2 (ja) * 2004-09-23 2013-04-17 ウィスタ ラボラトリーズ リミテッド メチルチオニニウム塩化物(mtc)などのジアミノフェノチアジニウム化合物を化学合成および精製する方法
EP3564223A1 (en) * 2004-09-23 2019-11-06 WisTa Laboratories Ltd. Methods of chemical synthesis and purification of diaminophenothiazinium compounds including methylthioninium chloride (mtc)
WO2006091728A2 (en) * 2005-02-24 2006-08-31 The Trustees Of The University Of Pennsylvania Microtubule stabilizing compounds and methods of their use
DK2853293T3 (en) * 2006-03-29 2018-01-22 Wista Lab Ltd Thioninium compounds and their use
CN101460157B (zh) * 2006-03-29 2015-09-02 维斯塔实验室有限公司 蛋白聚集抑制剂
AU2007231124B2 (en) * 2006-03-29 2013-02-21 TauRx Therapeutics Management Ltd 3,7-diamino-10H-phenothiazine salts and their use
SI2457904T1 (sl) 2006-07-11 2015-02-27 Wista Laboratories Ltd. Postopki sinteze in/ali čiščenje diaminofenotiazinijevih spojin

Also Published As

Publication number Publication date
MY177001A (en) 2020-09-01
WO2008155533A3 (en) 2009-02-19
EP2167095B1 (en) 2019-05-29
CA2690746C (en) 2018-01-02
CN101820884B (zh) 2013-08-28
AU2008265045A1 (en) 2008-12-24
DK2167095T3 (da) 2019-07-29
CA2690746A1 (en) 2008-12-24
SI2167095T1 (sl) 2019-09-30
PT2167095T (pt) 2019-08-06
EP2167095A2 (en) 2010-03-31
JP5725605B2 (ja) 2015-05-27
PL2167095T3 (pl) 2019-11-29
US9211294B2 (en) 2015-12-15
CN101820884A (zh) 2010-09-01
WO2008155533A2 (en) 2008-12-24
US20100184752A1 (en) 2010-07-22
AU2008265045B2 (en) 2014-02-27
HUE045460T2 (hu) 2019-12-30
JP2010530403A (ja) 2010-09-09
HRP20191513T1 (hr) 2019-11-29
ES2739546T3 (es) 2020-01-31

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Legal Events

Date Code Title Description
B25G Requested change of headquarter approved

Owner name: WISTA LABORATORIES LTD. (SG)

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

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