SI2167095T1 - Fenotiazinske spojine za zdravljenje blage kognitivne motnje - Google Patents
Fenotiazinske spojine za zdravljenje blage kognitivne motnjeInfo
- Publication number
- SI2167095T1 SI2167095T1 SI200832080T SI200832080T SI2167095T1 SI 2167095 T1 SI2167095 T1 SI 2167095T1 SI 200832080 T SI200832080 T SI 200832080T SI 200832080 T SI200832080 T SI 200832080T SI 2167095 T1 SI2167095 T1 SI 2167095T1
- Authority
- SI
- Slovenia
- Prior art keywords
- cognitive impairment
- mild cognitive
- treating mild
- phenothiazine compounds
- phenothiazine
- Prior art date
Links
- 208000010877 cognitive disease Diseases 0.000 title 1
- 208000027061 mild cognitive impairment Diseases 0.000 title 1
- 125000001484 phenothiazinyl group Chemical class C1(=CC=CC=2SC3=CC=CC=C3NC12)* 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US94500607P | 2007-06-19 | 2007-06-19 | |
| PCT/GB2008/002066 WO2008155533A2 (en) | 2007-06-19 | 2008-06-17 | Phenothiazine compounds for treating mild cognitive impairment |
| EP08762390.6A EP2167095B1 (en) | 2007-06-19 | 2008-06-17 | Phenothiazine compounds for treating mild cognitive impairment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI2167095T1 true SI2167095T1 (sl) | 2019-09-30 |
Family
ID=39943003
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI200832080T SI2167095T1 (sl) | 2007-06-19 | 2008-06-17 | Fenotiazinske spojine za zdravljenje blage kognitivne motnje |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US9211294B2 (enExample) |
| EP (1) | EP2167095B1 (enExample) |
| JP (1) | JP5725605B2 (enExample) |
| CN (1) | CN101820884B (enExample) |
| AU (1) | AU2008265045B2 (enExample) |
| BR (1) | BRPI0813670A2 (enExample) |
| CA (1) | CA2690746C (enExample) |
| DK (1) | DK2167095T3 (enExample) |
| ES (1) | ES2739546T3 (enExample) |
| HR (1) | HRP20191513T1 (enExample) |
| HU (1) | HUE045460T2 (enExample) |
| MY (1) | MY177001A (enExample) |
| PL (1) | PL2167095T3 (enExample) |
| PT (1) | PT2167095T (enExample) |
| SI (1) | SI2167095T1 (enExample) |
| WO (1) | WO2008155533A2 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL2013191T6 (pl) | 2006-03-29 | 2019-07-31 | Wista Laboratories Ltd. | Sole 3,7-diamino-10H-fenotiazynowe i ich zastosowanie |
| MY161656A (en) * | 2007-10-03 | 2017-04-28 | Wista Lab Ltd | Therapeutic use of diaminophenothiazines |
| SG185094A1 (en) | 2010-04-30 | 2012-12-28 | Prostetta Antiviral Inc | Antiviral compounds |
| PT2673266T (pt) * | 2011-02-11 | 2016-10-07 | Wista Lab Ltd | Sais de fenotiazina diamínio e sua utilização |
| EP2699241B1 (en) | 2011-04-20 | 2016-07-27 | Prosetta Antiviral Inc. | Antiviral compounds |
| EP2951149B1 (en) * | 2013-01-30 | 2018-10-10 | Ecolab USA Inc. | Hydrogen sulfide scavengers |
| US10304006B2 (en) * | 2013-02-15 | 2019-05-28 | The Charles Stark Draper Laboratory, Inc. | Method for integrating and fusing heterogeneous data types to perform predictive analysis |
| WO2016133995A1 (en) * | 2015-02-17 | 2016-08-25 | Arizona Board Of Regents On Behalf Of Arizona State University | Phenothiazine analogues as mitochondrial therapeutic agents |
| FI3487505T3 (fi) | 2016-07-25 | 2023-06-05 | Wista Lab Ltd | Diaminofenotiatsiinien antaminen ja annostus |
| GB201614834D0 (en) * | 2016-09-01 | 2016-10-19 | Wista Lab Ltd | Treatment of dementia |
| SI3826639T1 (sl) | 2018-07-26 | 2025-01-31 | Wista Laboratories Ltd. | Optimizirano odmerjanje diaminofenotiazinov v populacijah |
| MY209608A (en) * | 2019-04-10 | 2025-07-24 | Genting Taurx Diagnostic Centre Sdn Bhd | Adaptive neurological testing method |
| GB201909454D0 (en) * | 2019-07-01 | 2019-08-14 | Wista Lab Ltd | Enhancers |
| GB201909493D0 (en) | 2019-07-01 | 2019-08-14 | Wista Lab Ltd | Therapeutic interactions |
| GB201909506D0 (en) | 2019-07-02 | 2019-08-14 | Wista Lab Ltd | Synaptopathies |
| AU2023279800A1 (en) | 2022-05-31 | 2024-12-19 | TauRx Therapeutics Management Ltd | Treatment of neurodegenerative disorders utilising methylthioninium (mt)-containing compounds |
| WO2024184146A1 (en) | 2023-03-03 | 2024-09-12 | Wista Laboratories Ltd. | Diaminophenothiazine for the treatment of microvascular brain disease disease |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9506197D0 (en) * | 1995-03-27 | 1995-05-17 | Hoffmann La Roche | Inhibition of tau-tau association. |
| GB0017060D0 (en) * | 2000-07-11 | 2000-08-30 | Hunter Fleming Ltd | Production, stabilisation and use of reduced forms of pharmaceutical compounds |
| GB0101049D0 (en) | 2001-01-15 | 2001-02-28 | Univ Aberdeen | Materials and methods relating to protein aggregation in neurodegenerative disease |
| WO2004087160A1 (en) * | 2003-04-03 | 2004-10-14 | Prana Biotechnology Ltd | Treatment of neurological conditions |
| CA2579169C (en) * | 2004-09-23 | 2018-03-06 | Wista Laboratories Ltd. | Methods of chemical synthesis and purification of diaminophenothiazinium compounds including methylthioninium chloride (mtc) |
| JP5186212B2 (ja) * | 2004-09-23 | 2013-04-17 | ウィスタ ラボラトリーズ リミテッド | メチルチオニニウム塩化物（ｍｔｃ）などのジアミノフェノチアジニウム化合物を化学合成および精製する方法 |
| WO2006091728A2 (en) * | 2005-02-24 | 2006-08-31 | The Trustees Of The University Of Pennsylvania | Microtubule stabilizing compounds and methods of their use |
| CN101460157B (zh) | 2006-03-29 | 2015-09-02 | 维斯塔实验室有限公司 | 蛋白聚集抑制剂 |
| PL2013191T6 (pl) | 2006-03-29 | 2019-07-31 | Wista Laboratories Ltd. | Sole 3,7-diamino-10H-fenotiazynowe i ich zastosowanie |
| CN101460222B (zh) | 2006-03-29 | 2013-12-04 | 维斯塔实验室有限公司 | 锍化合物及其用途 |
| MY148145A (en) * | 2006-07-11 | 2013-03-15 | Wista Lab Ltd | Methods of synthesis and/or purification of diaminophenothiazinium compounds |
-
2008
- 2008-06-17 HU HUE08762390A patent/HUE045460T2/hu unknown
- 2008-06-17 CA CA2690746A patent/CA2690746C/en active Active
- 2008-06-17 BR BRPI0813670-0A2A patent/BRPI0813670A2/pt not_active Application Discontinuation
- 2008-06-17 PL PL08762390T patent/PL2167095T3/pl unknown
- 2008-06-17 WO PCT/GB2008/002066 patent/WO2008155533A2/en not_active Ceased
- 2008-06-17 US US12/665,608 patent/US9211294B2/en active Active
- 2008-06-17 MY MYPI20095255A patent/MY177001A/en unknown
- 2008-06-17 HR HRP20191513 patent/HRP20191513T1/hr unknown
- 2008-06-17 ES ES08762390T patent/ES2739546T3/es active Active
- 2008-06-17 DK DK08762390.6T patent/DK2167095T3/da active
- 2008-06-17 CN CN2008801031955A patent/CN101820884B/zh active Active
- 2008-06-17 JP JP2010512761A patent/JP5725605B2/ja active Active
- 2008-06-17 AU AU2008265045A patent/AU2008265045B2/en active Active
- 2008-06-17 PT PT08762390T patent/PT2167095T/pt unknown
- 2008-06-17 EP EP08762390.6A patent/EP2167095B1/en active Active
- 2008-06-17 SI SI200832080T patent/SI2167095T1/sl unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL2167095T3 (pl) | 2019-11-29 |
| US20100184752A1 (en) | 2010-07-22 |
| CN101820884A (zh) | 2010-09-01 |
| JP5725605B2 (ja) | 2015-05-27 |
| CN101820884B (zh) | 2013-08-28 |
| WO2008155533A2 (en) | 2008-12-24 |
| DK2167095T3 (da) | 2019-07-29 |
| EP2167095B1 (en) | 2019-05-29 |
| EP2167095A2 (en) | 2010-03-31 |
| PT2167095T (pt) | 2019-08-06 |
| CA2690746C (en) | 2018-01-02 |
| MY177001A (en) | 2020-09-01 |
| JP2010530403A (ja) | 2010-09-09 |
| HUE045460T2 (hu) | 2019-12-30 |
| AU2008265045A1 (en) | 2008-12-24 |
| BRPI0813670A2 (pt) | 2014-12-30 |
| HRP20191513T1 (hr) | 2019-11-29 |
| US9211294B2 (en) | 2015-12-15 |
| CA2690746A1 (en) | 2008-12-24 |
| AU2008265045B2 (en) | 2014-02-27 |
| WO2008155533A3 (en) | 2009-02-19 |
| ES2739546T3 (es) | 2020-01-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HUE045460T2 (hu) | Fenotiazin vegyületek enyhe kognitív zavar kezelésére | |
| EP2504011A4 (en) | METHOD FOR TREATING EASY COGNITIVE IMPAIRMENT | |
| IL209895A0 (en) | Compounds for treating beta-amyloidoses | |
| GB2445465B (en) | Process for waste treatment | |
| IL198851A0 (en) | Methods for treating hypercholesterolemia | |
| EP2079414A4 (en) | SYSTEM FOR CHEMOHYPER THERMAL TREATMENT | |
| AP2009004746A0 (en) | Process for prepaiIrng diaminophenothiazinium compounds | |
| LT3028716T (lt) | Komplemento slopinimas nervų regeneracijos pagerinimui | |
| EP1877055A4 (en) | 4-AMINOQUINOLINE COMPOUNDS FOR THE TREATMENT OF VIRAL DISEASE CONDITIONS | |
| ZA200809528B (en) | Treatment for depressive disorders | |
| PL2001892T3 (pl) | Imidazolotiazolowe związki do leczenia chorób proliferacyjnych | |
| AU2007288337A8 (en) | Compounds for treating proliferative disorders | |
| IL193410A0 (en) | Purification method for effluent | |
| ZA200809527B (en) | Treatment for depressive disorders | |
| IL213398A0 (en) | Compounds for treating cancer | |
| IL204728A0 (en) | Methods and compounds for treating retinol-related diseases | |
| IL198856A0 (en) | Compounds useful for treating neurodegenerative disorders | |
| GB0810364D0 (en) | Improved effluent treatment | |
| PT2481407T (pt) | Compostos para utilização no tratamento de distúrbios cognitivos | |
| ZA201002993B (en) | Novel compounds for fabric treatment | |
| IL209947A (en) | Compounds for the treatment of corneal inflammation | |
| GB0707556D0 (en) | Treatment for cancer | |
| ZA200901672B (en) | Compounds for treating proliferative disorders | |
| IL205752A0 (en) | Octahydroquinolizines for antidiabetic treatment | |
| PL2043792T3 (pl) | System do obróbki ciągłej |