SI2167095T1 - Fenotiazinske spojine za zdravljenje blage kognitivne motnje - Google Patents

Fenotiazinske spojine za zdravljenje blage kognitivne motnje

Info

Publication number
SI2167095T1
SI2167095T1 SI200832080T SI200832080T SI2167095T1 SI 2167095 T1 SI2167095 T1 SI 2167095T1 SI 200832080 T SI200832080 T SI 200832080T SI 200832080 T SI200832080 T SI 200832080T SI 2167095 T1 SI2167095 T1 SI 2167095T1
Authority
SI
Slovenia
Prior art keywords
cognitive impairment
mild cognitive
treating mild
phenothiazine compounds
phenothiazine
Prior art date
Application number
SI200832080T
Other languages
English (en)
Slovenian (sl)
Inventor
Claude Michel Wischik
Dominic Venay Harbaran
Gernot Riedel
Serena Deiana
Elizabeth Anne Goatman
Damon Jude Wischik
Alison Dorothy Murray
Roger Todd Staff
Original Assignee
Wista Laboratories Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wista Laboratories Ltd. filed Critical Wista Laboratories Ltd.
Publication of SI2167095T1 publication Critical patent/SI2167095T1/sl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SI200832080T 2007-06-19 2008-06-17 Fenotiazinske spojine za zdravljenje blage kognitivne motnje SI2167095T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US94500607P 2007-06-19 2007-06-19
PCT/GB2008/002066 WO2008155533A2 (en) 2007-06-19 2008-06-17 Phenothiazine compounds for treating mild cognitive impairment
EP08762390.6A EP2167095B1 (en) 2007-06-19 2008-06-17 Phenothiazine compounds for treating mild cognitive impairment

Publications (1)

Publication Number Publication Date
SI2167095T1 true SI2167095T1 (sl) 2019-09-30

Family

ID=39943003

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200832080T SI2167095T1 (sl) 2007-06-19 2008-06-17 Fenotiazinske spojine za zdravljenje blage kognitivne motnje

Country Status (16)

Country Link
US (1) US9211294B2 (enExample)
EP (1) EP2167095B1 (enExample)
JP (1) JP5725605B2 (enExample)
CN (1) CN101820884B (enExample)
AU (1) AU2008265045B2 (enExample)
BR (1) BRPI0813670A2 (enExample)
CA (1) CA2690746C (enExample)
DK (1) DK2167095T3 (enExample)
ES (1) ES2739546T3 (enExample)
HR (1) HRP20191513T1 (enExample)
HU (1) HUE045460T2 (enExample)
MY (1) MY177001A (enExample)
PL (1) PL2167095T3 (enExample)
PT (1) PT2167095T (enExample)
SI (1) SI2167095T1 (enExample)
WO (1) WO2008155533A2 (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE602007008550D1 (de) 2006-03-29 2010-09-30 Wista Lab Ltd 3,7-diamino-10h-phenothiazinsalze und ihre verwendung
SI2954932T1 (sl) * 2007-10-03 2019-01-31 Wista Laboratories Ltd. Terapevtska uporaba diaminofenotiazinov
SG185094A1 (en) 2010-04-30 2012-12-28 Prostetta Antiviral Inc Antiviral compounds
SI2673266T1 (sl) * 2011-02-11 2016-11-30 Wista Laboratories Ltd. Fenotiazin diaminijeve soli in njihova uporaba
WO2012145567A1 (en) 2011-04-20 2012-10-26 Prosetta Antiviral Inc. Antiviral compounds
EP3686181B1 (en) * 2013-01-30 2024-07-17 Ecolab USA Inc. Hydrogen sulfide scavengers
US10304006B2 (en) * 2013-02-15 2019-05-28 The Charles Stark Draper Laboratory, Inc. Method for integrating and fusing heterogeneous data types to perform predictive analysis
AU2016220096B2 (en) 2015-02-17 2020-01-30 Arizona Board Of Regents On Behalf Of Arizona State University Phenothiazine analogues as mitochondrial therapeutic agents
SI4335517T1 (sl) * 2016-07-25 2025-11-28 Taurx Therapeutics Management Ltd. Dajanje in odmerek diaminofenotiazinov
GB201614834D0 (en) * 2016-09-01 2016-10-19 Wista Lab Ltd Treatment of dementia
EP4385512B1 (en) * 2018-07-26 2025-12-03 TauRx Therapeutics Management Ltd. Optimised dosage of diaminophenothiazines in populations
MY209608A (en) * 2019-04-10 2025-07-24 Genting Taurx Diagnostic Centre Sdn Bhd Adaptive neurological testing method
GB201909454D0 (en) 2019-07-01 2019-08-14 Wista Lab Ltd Enhancers
GB201909493D0 (en) 2019-07-01 2019-08-14 Wista Lab Ltd Therapeutic interactions
GB201909506D0 (en) 2019-07-02 2019-08-14 Wista Lab Ltd Synaptopathies
CA3257856A1 (en) 2022-05-31 2023-12-07 Wista Laboratories Ltd. TREATMENT OF NEURODEGENERATIVE DISORDERS USING COMPOUNDS CONTAINING METHYLTHIONINIUM (MT)
KR20250154422A (ko) 2023-03-03 2025-10-28 타우알엑스 쎄라퓨틱스 매니지먼트 리미티드 미세혈관 뇌질환 치료를 위한 디아미노페노티아진

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9506197D0 (en) 1995-03-27 1995-05-17 Hoffmann La Roche Inhibition of tau-tau association.
GB0017060D0 (en) * 2000-07-11 2000-08-30 Hunter Fleming Ltd Production, stabilisation and use of reduced forms of pharmaceutical compounds
GB0101049D0 (en) 2001-01-15 2001-02-28 Univ Aberdeen Materials and methods relating to protein aggregation in neurodegenerative disease
EP1617844A4 (en) * 2003-04-03 2009-07-22 Prana Biotechnology Ltd TREATMENT OF NEUROLOGICAL DISEASES
WO2006032879A2 (en) * 2004-09-23 2006-03-30 Wista Laboratories Ltd. Methods of chemical synthesis and purification of diaminophenothiazinium compounds including methylthioninium chloride (mtc)
CN101084204B (zh) * 2004-09-23 2012-12-05 卫思道制药有限公司 包括亚甲蓝(mtc)在内的二氨基吩噻嗪鎓化合物的化学合成和纯化方法
WO2006091728A2 (en) * 2005-02-24 2006-08-31 The Trustees Of The University Of Pennsylvania Microtubule stabilizing compounds and methods of their use
EP2001556B1 (en) * 2006-03-29 2014-10-01 Wista Laboratories Ltd. Thioninium compounds and their use
DE602007008550D1 (de) 2006-03-29 2010-09-30 Wista Lab Ltd 3,7-diamino-10h-phenothiazinsalze und ihre verwendung
WO2007110629A1 (en) 2006-03-29 2007-10-04 Wista Laboratories Ltd Inhibitors of protein aggregation
SI2457905T1 (sl) 2006-07-11 2016-12-30 Wista Laboratories Ltd. Postopki sinteze in/ali čiščenja diaminofenotiazinijevih spojin

Also Published As

Publication number Publication date
AU2008265045B2 (en) 2014-02-27
BRPI0813670A2 (pt) 2014-12-30
JP5725605B2 (ja) 2015-05-27
HUE045460T2 (hu) 2019-12-30
HRP20191513T1 (hr) 2019-11-29
US20100184752A1 (en) 2010-07-22
ES2739546T3 (es) 2020-01-31
CN101820884B (zh) 2013-08-28
EP2167095B1 (en) 2019-05-29
AU2008265045A1 (en) 2008-12-24
DK2167095T3 (da) 2019-07-29
CA2690746C (en) 2018-01-02
US9211294B2 (en) 2015-12-15
MY177001A (en) 2020-09-01
CA2690746A1 (en) 2008-12-24
WO2008155533A3 (en) 2009-02-19
PT2167095T (pt) 2019-08-06
PL2167095T3 (pl) 2019-11-29
WO2008155533A2 (en) 2008-12-24
CN101820884A (zh) 2010-09-01
JP2010530403A (ja) 2010-09-09
EP2167095A2 (en) 2010-03-31

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