PL2853293T3 - Związki tioniny i ich zastosowanie - Google Patents
Związki tioniny i ich zastosowanieInfo
- Publication number
- PL2853293T3 PL2853293T3 PL14185157T PL14185157T PL2853293T3 PL 2853293 T3 PL2853293 T3 PL 2853293T3 PL 14185157 T PL14185157 T PL 14185157T PL 14185157 T PL14185157 T PL 14185157T PL 2853293 T3 PL2853293 T3 PL 2853293T3
- Authority
- PL
- Poland
- Prior art keywords
- thioninium
- compounds
- thioninium compounds
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US78669906P | 2006-03-29 | 2006-03-29 | |
| EP14185157.6A EP2853293B1 (en) | 2006-03-29 | 2007-03-28 | Thioninium compounds and their use |
| EP07712962.5A EP2001556B1 (en) | 2006-03-29 | 2007-03-28 | Thioninium compounds and their use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2853293T3 true PL2853293T3 (pl) | 2018-05-30 |
Family
ID=38163667
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL07712962T PL2001556T3 (pl) | 2006-03-29 | 2007-03-28 | Związki tioniny i ich zastosowanie |
| PL14185157T PL2853293T3 (pl) | 2006-03-29 | 2007-03-28 | Związki tioniny i ich zastosowanie |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL07712962T PL2001556T3 (pl) | 2006-03-29 | 2007-03-28 | Związki tioniny i ich zastosowanie |
Country Status (13)
| Country | Link |
|---|---|
| EP (2) | EP2001556B1 (pl) |
| JP (1) | JP5184507B2 (pl) |
| CN (2) | CN103641794B (pl) |
| AU (1) | AU2007231127B2 (pl) |
| CA (1) | CA2645919C (pl) |
| DK (2) | DK2001556T3 (pl) |
| ES (2) | ES2525001T3 (pl) |
| HR (2) | HRP20141261T1 (pl) |
| MY (2) | MY162640A (pl) |
| PL (2) | PL2001556T3 (pl) |
| PT (2) | PT2853293T (pl) |
| SI (2) | SI2853293T1 (pl) |
| WO (1) | WO2007110630A1 (pl) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2013191T6 (en) | 2006-03-29 | 2019-04-23 | Wista Lab Ltd | 3,7-Diamino-10H-phenothiazine salts and their use |
| AU2008265045B2 (en) * | 2007-06-19 | 2014-02-27 | Wista Laboratories Ltd. | Phenothiazine compounds for treating Mild Cognitive Impairment |
| MX367131B (es) | 2008-12-10 | 2019-08-06 | Wista Lab Ltd | Sales de xantilio 3,6-disustituidas. |
| CN102958525B (zh) | 2010-04-30 | 2017-05-24 | 普罗瑟塔抗病毒股份有限公司 | 抗病毒化合物 |
| US8828986B2 (en) | 2011-04-20 | 2014-09-09 | Prosetta Antiviral Inc. | Antiviral compounds |
| CA2827027C (en) | 2011-02-11 | 2019-06-04 | Wista Laboratories Ltd. | Phenothiazine diaminium salts and their use |
| CN102690244A (zh) * | 2011-03-22 | 2012-09-26 | 中国科学院上海生命科学研究院 | 调节α-突触核蛋白积聚的物质及其制药用途 |
| GB201317702D0 (en) * | 2013-10-07 | 2013-11-20 | Wista Lab Ltd | Methods of chemical synthesis of diaminophenothiazinium compounds including methylthioninium chloride (MTC) |
| GB201512678D0 (en) | 2015-07-20 | 2015-08-26 | Wista Lab Ltd | Methods of chemical synthesis |
| KR20230058533A (ko) | 2016-07-25 | 2023-05-03 | 위스타 레보레이토리스 리미티드 | 디아미노페노티아진 (diaminophenothiazines)의 투여 및 투여량 (dosage) |
| GB201614834D0 (en) * | 2016-09-01 | 2016-10-19 | Wista Lab Ltd | Treatment of dementia |
| GB201621817D0 (en) * | 2016-12-21 | 2017-02-01 | Wista Lab Ltd | Methods of chemical synthesis |
| EP4364801B1 (en) | 2018-07-26 | 2025-11-12 | TauRx Therapeutics Management Ltd. | Optimised dosage of diaminophenothiazines in populations |
| US12215234B2 (en) * | 2019-09-21 | 2025-02-04 | RK Pharma Solutions LLC | Process for the purification of methylene blue |
| GB202010652D0 (en) | 2020-07-10 | 2020-08-26 | Wista Lab Ltd | Anti-tau antibodies |
| JP2025518248A (ja) | 2022-05-31 | 2025-06-12 | ウィスタ ラボラトリーズ リミテッド | メチルチオニニウム（ｍｔ）含有化合物を利用した神経変性障害の処置 |
| CN119947729A (zh) | 2022-09-21 | 2025-05-06 | 罗颍诗 | 二氨基吩噻嗪的口服制剂及其在治疗和/或预防疾病中的制备和使用方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1996004915A1 (en) * | 1994-08-08 | 1996-02-22 | Albert Einstein College Of Medicine Of Yeshiva University | Methods for treating and/or preventing alzheimer's disease using phenothiazines and/or thioxanthenes |
| GB9506197D0 (en) * | 1995-03-27 | 1995-05-17 | Hoffmann La Roche | Inhibition of tau-tau association. |
| JP2000344685A (ja) * | 1999-03-26 | 2000-12-12 | Bf Kenkyusho:Kk | アズールａ類似化合物によるアミロイドが蓄積する疾患の画像診断プローブおよびそれを含む画像診断用組成物 |
| GB0101049D0 (en) | 2001-01-15 | 2001-02-28 | Univ Aberdeen | Materials and methods relating to protein aggregation in neurodegenerative disease |
| GB0106953D0 (en) * | 2001-03-20 | 2001-05-09 | Univ Aberdeen | Neufofibrillary labels |
| GB0322756D0 (en) | 2003-09-29 | 2003-10-29 | Univ Aberdeen | Methods of chemical synthesis |
| BRPI0416928A (pt) * | 2003-11-28 | 2007-01-16 | Photopharmica Ltd | desenvolvimento de derivados biologicamente ativos de azul de metileno |
| ES2736160T3 (es) | 2004-09-23 | 2019-12-26 | Wista Lab Ltd | Procedimientos de síntesis química y purificación de compuestos de diaminofenotiazinio que incluyen cloruro de metiltioninio (CMT) |
| US7790881B2 (en) * | 2004-09-23 | 2010-09-07 | Wista Laboratories Ltd. | Methods of chemical synthesis and purification of diaminophenothiazinium compounds including methylthioninium chloride (MTC) |
-
2007
- 2007-03-28 PL PL07712962T patent/PL2001556T3/pl unknown
- 2007-03-28 SI SI200732008T patent/SI2853293T1/en unknown
- 2007-03-28 CN CN201310514618.5A patent/CN103641794B/zh active Active
- 2007-03-28 MY MYPI20083822A patent/MY162640A/en unknown
- 2007-03-28 HR HRP20141261TT patent/HRP20141261T1/hr unknown
- 2007-03-28 PT PT141851576T patent/PT2853293T/pt unknown
- 2007-03-28 PL PL14185157T patent/PL2853293T3/pl unknown
- 2007-03-28 PT PT77129625T patent/PT2001556E/pt unknown
- 2007-03-28 SI SI200731541T patent/SI2001556T1/sl unknown
- 2007-03-28 CA CA2645919A patent/CA2645919C/en active Active
- 2007-03-28 ES ES07712962.5T patent/ES2525001T3/es active Active
- 2007-03-28 JP JP2009502207A patent/JP5184507B2/ja active Active
- 2007-03-28 ES ES14185157.6T patent/ES2659030T3/es active Active
- 2007-03-28 MY MYPI2014003327A patent/MY172157A/en unknown
- 2007-03-28 DK DK07712962.5T patent/DK2001556T3/da active
- 2007-03-28 AU AU2007231127A patent/AU2007231127B2/en active Active
- 2007-03-28 DK DK14185157.6T patent/DK2853293T3/en active
- 2007-03-28 EP EP07712962.5A patent/EP2001556B1/en active Active
- 2007-03-28 WO PCT/GB2007/001107 patent/WO2007110630A1/en not_active Ceased
- 2007-03-28 CN CN2007800202730A patent/CN101460222B/zh active Active
- 2007-03-28 EP EP14185157.6A patent/EP2853293B1/en active Active
-
2018
- 2018-02-02 HR HRP20180204TT patent/HRP20180204T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2645919C (en) | 2016-05-31 |
| CN101460222B (zh) | 2013-12-04 |
| AU2007231127B2 (en) | 2013-03-14 |
| EP2001556A1 (en) | 2008-12-17 |
| CN103641794A (zh) | 2014-03-19 |
| EP2853293A1 (en) | 2015-04-01 |
| MY172157A (en) | 2019-11-15 |
| JP5184507B2 (ja) | 2013-04-17 |
| HK1208000A1 (en) | 2016-02-19 |
| SI2853293T1 (en) | 2018-03-30 |
| PT2853293T (pt) | 2018-02-13 |
| JP2009531405A (ja) | 2009-09-03 |
| EP2853293B1 (en) | 2017-11-22 |
| MY162640A (en) | 2017-06-30 |
| SI2001556T1 (sl) | 2014-12-31 |
| WO2007110630A1 (en) | 2007-10-04 |
| EP2001556B1 (en) | 2014-10-01 |
| DK2853293T3 (en) | 2018-01-22 |
| PT2001556E (pt) | 2014-12-09 |
| HK1121084A1 (en) | 2009-04-17 |
| DK2001556T3 (da) | 2014-11-10 |
| HRP20180204T1 (hr) | 2018-03-09 |
| AU2007231127A1 (en) | 2007-10-04 |
| ES2525001T3 (es) | 2014-12-16 |
| CN101460222A (zh) | 2009-06-17 |
| PL2001556T3 (pl) | 2015-03-31 |
| CA2645919A1 (en) | 2007-10-04 |
| CN103641794B (zh) | 2016-09-21 |
| ES2659030T3 (es) | 2018-03-13 |
| HRP20141261T1 (xx) | 2015-03-13 |
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