PL2853293T3 - Związki tioniny i ich zastosowanie - Google Patents
Związki tioniny i ich zastosowanieInfo
- Publication number
- PL2853293T3 PL2853293T3 PL14185157T PL14185157T PL2853293T3 PL 2853293 T3 PL2853293 T3 PL 2853293T3 PL 14185157 T PL14185157 T PL 14185157T PL 14185157 T PL14185157 T PL 14185157T PL 2853293 T3 PL2853293 T3 PL 2853293T3
- Authority
- PL
- Poland
- Prior art keywords
- thioninium
- compounds
- thioninium compounds
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US78669906P | 2006-03-29 | 2006-03-29 | |
| EP14185157.6A EP2853293B1 (en) | 2006-03-29 | 2007-03-28 | Thioninium compounds and their use |
| EP07712962.5A EP2001556B1 (en) | 2006-03-29 | 2007-03-28 | Thioninium compounds and their use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2853293T3 true PL2853293T3 (pl) | 2018-05-30 |
Family
ID=38163667
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL14185157T PL2853293T3 (pl) | 2006-03-29 | 2007-03-28 | Związki tioniny i ich zastosowanie |
| PL07712962T PL2001556T3 (pl) | 2006-03-29 | 2007-03-28 | Związki tioniny i ich zastosowanie |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL07712962T PL2001556T3 (pl) | 2006-03-29 | 2007-03-28 | Związki tioniny i ich zastosowanie |
Country Status (13)
| Country | Link |
|---|---|
| EP (2) | EP2853293B1 (pl) |
| JP (1) | JP5184507B2 (pl) |
| CN (2) | CN101460222B (pl) |
| AU (1) | AU2007231127B2 (pl) |
| CA (1) | CA2645919C (pl) |
| DK (2) | DK2853293T3 (pl) |
| ES (2) | ES2659030T3 (pl) |
| HR (2) | HRP20141261T1 (pl) |
| MY (2) | MY162640A (pl) |
| PL (2) | PL2853293T3 (pl) |
| PT (2) | PT2001556E (pl) |
| SI (2) | SI2001556T1 (pl) |
| WO (1) | WO2007110630A1 (pl) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE602007008550D1 (de) | 2006-03-29 | 2010-09-30 | Wista Lab Ltd | 3,7-diamino-10h-phenothiazinsalze und ihre verwendung |
| BRPI0813670A2 (pt) | 2007-06-19 | 2014-12-30 | Wista Lab Ltd | Compostos para tratamento |
| SI2373660T1 (sl) | 2008-12-10 | 2016-12-30 | Wista Laboratories Ltd. | 3,6-disubstituirane ksantilijeve soli kot zdravila |
| CN102958525B (zh) | 2010-04-30 | 2017-05-24 | 普罗瑟塔抗病毒股份有限公司 | 抗病毒化合物 |
| AU2011358840B2 (en) | 2011-02-11 | 2017-05-04 | TauRx Therapeutics Management Ltd | Phenothiazine diaminium salts and their use |
| CN102690244A (zh) * | 2011-03-22 | 2012-09-26 | 中国科学院上海生命科学研究院 | 调节α-突触核蛋白积聚的物质及其制药用途 |
| WO2012145567A1 (en) | 2011-04-20 | 2012-10-26 | Prosetta Antiviral Inc. | Antiviral compounds |
| GB201317702D0 (en) * | 2013-10-07 | 2013-11-20 | Wista Lab Ltd | Methods of chemical synthesis of diaminophenothiazinium compounds including methylthioninium chloride (MTC) |
| GB201512678D0 (en) | 2015-07-20 | 2015-08-26 | Wista Lab Ltd | Methods of chemical synthesis |
| EP4335517B8 (en) | 2016-07-25 | 2025-10-22 | TauRx Therapeutics Management Ltd. | Administration and dosage of diaminophenothiazines |
| GB201614834D0 (en) * | 2016-09-01 | 2016-10-19 | Wista Lab Ltd | Treatment of dementia |
| GB201621817D0 (en) | 2016-12-21 | 2017-02-01 | Wista Lab Ltd | Methods of chemical synthesis |
| US12280061B2 (en) | 2018-07-26 | 2025-04-22 | Wista Laboratories Ltd. | Optimised dosage of diaminophenothiazines in populations |
| US12215234B2 (en) * | 2019-09-21 | 2025-02-04 | RK Pharma Solutions LLC | Process for the purification of methylene blue |
| GB202010652D0 (en) | 2020-07-10 | 2020-08-26 | Wista Lab Ltd | Anti-tau antibodies |
| WO2023232764A1 (en) | 2022-05-31 | 2023-12-07 | Wista Laboratories Ltd. | Treatment of neurodegenerative disorders utilising methylthioninium (mt)-containing compounds |
| CN119947729A (zh) | 2022-09-21 | 2025-05-06 | 罗颍诗 | 二氨基吩噻嗪的口服制剂及其在治疗和/或预防疾病中的制备和使用方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1996004915A1 (en) | 1994-08-08 | 1996-02-22 | Albert Einstein College Of Medicine Of Yeshiva University | Methods for treating and/or preventing alzheimer's disease using phenothiazines and/or thioxanthenes |
| GB9506197D0 (en) * | 1995-03-27 | 1995-05-17 | Hoffmann La Roche | Inhibition of tau-tau association. |
| JP2000344685A (ja) * | 1999-03-26 | 2000-12-12 | Bf Kenkyusho:Kk | アズールａ類似化合物によるアミロイドが蓄積する疾患の画像診断プローブおよびそれを含む画像診断用組成物 |
| GB0101049D0 (en) | 2001-01-15 | 2001-02-28 | Univ Aberdeen | Materials and methods relating to protein aggregation in neurodegenerative disease |
| GB0106953D0 (en) * | 2001-03-20 | 2001-05-09 | Univ Aberdeen | Neufofibrillary labels |
| GB0322756D0 (en) * | 2003-09-29 | 2003-10-29 | Univ Aberdeen | Methods of chemical synthesis |
| KR20060111536A (ko) * | 2003-11-28 | 2006-10-27 | 포토파미카 리미티드 | 생물학적 활성 메틸렌 블루 유도체(２)의 개발 |
| SI2322517T1 (sl) * | 2004-09-23 | 2019-06-28 | Wista Laboratories Ltd. | Postopki za kemijsko sintezo in čiščenje diaminofenotiazinijevih spojin, vključno metiltioninijevega klorida (MTC) |
| CN101084204B (zh) * | 2004-09-23 | 2012-12-05 | 卫思道制药有限公司 | 包括亚甲蓝(mtc)在内的二氨基吩噻嗪鎓化合物的化学合成和纯化方法 |
-
2007
- 2007-03-28 SI SI200731541T patent/SI2001556T1/sl unknown
- 2007-03-28 MY MYPI20083822A patent/MY162640A/en unknown
- 2007-03-28 PT PT77129625T patent/PT2001556E/pt unknown
- 2007-03-28 CN CN2007800202730A patent/CN101460222B/zh active Active
- 2007-03-28 HR HRP20141261TT patent/HRP20141261T1/hr unknown
- 2007-03-28 CN CN201310514618.5A patent/CN103641794B/zh active Active
- 2007-03-28 PL PL14185157T patent/PL2853293T3/pl unknown
- 2007-03-28 SI SI200732008T patent/SI2853293T1/en unknown
- 2007-03-28 EP EP14185157.6A patent/EP2853293B1/en active Active
- 2007-03-28 EP EP07712962.5A patent/EP2001556B1/en active Active
- 2007-03-28 DK DK14185157.6T patent/DK2853293T3/en active
- 2007-03-28 CA CA2645919A patent/CA2645919C/en active Active
- 2007-03-28 PL PL07712962T patent/PL2001556T3/pl unknown
- 2007-03-28 WO PCT/GB2007/001107 patent/WO2007110630A1/en not_active Ceased
- 2007-03-28 ES ES14185157.6T patent/ES2659030T3/es active Active
- 2007-03-28 ES ES07712962.5T patent/ES2525001T3/es active Active
- 2007-03-28 MY MYPI2014003327A patent/MY172157A/en unknown
- 2007-03-28 DK DK07712962.5T patent/DK2001556T3/da active
- 2007-03-28 AU AU2007231127A patent/AU2007231127B2/en active Active
- 2007-03-28 JP JP2009502207A patent/JP5184507B2/ja active Active
- 2007-03-28 PT PT141851576T patent/PT2853293T/pt unknown
-
2018
- 2018-02-02 HR HRP20180204TT patent/HRP20180204T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2009531405A (ja) | 2009-09-03 |
| HK1208000A1 (en) | 2016-02-19 |
| PT2853293T (pt) | 2018-02-13 |
| AU2007231127A1 (en) | 2007-10-04 |
| HK1121084A1 (en) | 2009-04-17 |
| CA2645919C (en) | 2016-05-31 |
| EP2853293A1 (en) | 2015-04-01 |
| JP5184507B2 (ja) | 2013-04-17 |
| WO2007110630A1 (en) | 2007-10-04 |
| CA2645919A1 (en) | 2007-10-04 |
| CN103641794A (zh) | 2014-03-19 |
| EP2001556A1 (en) | 2008-12-17 |
| CN103641794B (zh) | 2016-09-21 |
| CN101460222B (zh) | 2013-12-04 |
| DK2001556T3 (da) | 2014-11-10 |
| MY162640A (en) | 2017-06-30 |
| HRP20141261T1 (xx) | 2015-03-13 |
| SI2001556T1 (sl) | 2014-12-31 |
| DK2853293T3 (en) | 2018-01-22 |
| PL2001556T3 (pl) | 2015-03-31 |
| MY172157A (en) | 2019-11-15 |
| EP2853293B1 (en) | 2017-11-22 |
| EP2001556B1 (en) | 2014-10-01 |
| ES2659030T3 (es) | 2018-03-13 |
| PT2001556E (pt) | 2014-12-09 |
| HRP20180204T1 (hr) | 2018-03-09 |
| AU2007231127B2 (en) | 2013-03-14 |
| SI2853293T1 (en) | 2018-03-30 |
| CN101460222A (zh) | 2009-06-17 |
| ES2525001T3 (es) | 2014-12-16 |
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