SI2001556T1 - Tioninijeve spojine in njihova uporaba - Google Patents
Tioninijeve spojine in njihova uporabaInfo
- Publication number
- SI2001556T1 SI2001556T1 SI200731541T SI200731541T SI2001556T1 SI 2001556 T1 SI2001556 T1 SI 2001556T1 SI 200731541 T SI200731541 T SI 200731541T SI 200731541 T SI200731541 T SI 200731541T SI 2001556 T1 SI2001556 T1 SI 2001556T1
- Authority
- SI
- Slovenia
- Prior art keywords
- thioninium
- compounds
- thioninium compounds
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US78669906P | 2006-03-29 | 2006-03-29 | |
| PCT/GB2007/001107 WO2007110630A1 (en) | 2006-03-29 | 2007-03-28 | Thioninium compounds and their use |
| EP07712962.5A EP2001556B1 (en) | 2006-03-29 | 2007-03-28 | Thioninium compounds and their use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI2001556T1 true SI2001556T1 (sl) | 2014-12-31 |
Family
ID=38163667
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI200731541T SI2001556T1 (sl) | 2006-03-29 | 2007-03-28 | Tioninijeve spojine in njihova uporaba |
| SI200732008T SI2853293T1 (sl) | 2006-03-29 | 2007-03-28 | Tioninijeve spojine in njihova uporaba |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI200732008T SI2853293T1 (sl) | 2006-03-29 | 2007-03-28 | Tioninijeve spojine in njihova uporaba |
Country Status (14)
| Country | Link |
|---|---|
| EP (2) | EP2853293B1 (sl) |
| JP (1) | JP5184507B2 (sl) |
| CN (2) | CN101460222B (sl) |
| AU (1) | AU2007231127B2 (sl) |
| CA (1) | CA2645919C (sl) |
| DK (2) | DK2853293T3 (sl) |
| ES (2) | ES2659030T3 (sl) |
| HK (2) | HK1121084A1 (sl) |
| HR (2) | HRP20141261T1 (sl) |
| MY (2) | MY162640A (sl) |
| PL (2) | PL2001556T3 (sl) |
| PT (2) | PT2853293T (sl) |
| SI (2) | SI2001556T1 (sl) |
| WO (1) | WO2007110630A1 (sl) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101820884B (zh) | 2007-06-19 | 2013-08-28 | 维斯塔实验室有限公司 | 用于治疗轻度认知缺损的吩噻嗪化合物 |
| ES2600278T3 (es) * | 2008-12-10 | 2017-02-08 | Wista Laboratories Ltd. | Sales de xantilio 3,6-disustituidas como medicamentos |
| US8828986B2 (en) | 2011-04-20 | 2014-09-09 | Prosetta Antiviral Inc. | Antiviral compounds |
| US8785434B2 (en) | 2010-04-30 | 2014-07-22 | Prosetta Antiviral Inc. | Antiviral compounds |
| US9283230B2 (en) | 2011-02-11 | 2016-03-15 | Wista Laboratories Ltd. | Phenothiazine diaminium salts and their use |
| CN102690244A (zh) * | 2011-03-22 | 2012-09-26 | 中国科学院上海生命科学研究院 | 调节α-突触核蛋白积聚的物质及其制药用途 |
| GB201317702D0 (en) * | 2013-10-07 | 2013-11-20 | Wista Lab Ltd | Methods of chemical synthesis of diaminophenothiazinium compounds including methylthioninium chloride (MTC) |
| GB201512678D0 (en) | 2015-07-20 | 2015-08-26 | Wista Lab Ltd | Methods of chemical synthesis |
| EP4223297A3 (en) | 2016-07-25 | 2023-11-15 | WisTa Laboratories Ltd. | Administration and dosage of diaminophenothiazines |
| GB201614834D0 (en) * | 2016-09-01 | 2016-10-19 | Wista Lab Ltd | Treatment of dementia |
| GB201621817D0 (en) * | 2016-12-21 | 2017-02-01 | Wista Lab Ltd | Methods of chemical synthesis |
| BR112021000802A2 (pt) | 2018-07-26 | 2021-04-13 | Wista Laboratories Ltd. | Dosagem otimizada de diaminofenotiazinas em populações |
| US20220049102A1 (en) * | 2019-09-21 | 2022-02-17 | RK Pharma Solutions LLC | Process for the Purification of Methylene Blue |
| GB202010652D0 (en) | 2020-07-10 | 2020-08-26 | Wista Lab Ltd | Anti-tau antibodies |
| WO2023232764A1 (en) | 2022-05-31 | 2023-12-07 | Wista Laboratories Ltd. | Treatment of neurodegenerative disorders utilising methylthioninium (mt)-containing compounds |
| WO2024063700A1 (en) | 2022-09-21 | 2024-03-28 | Yin Sze Loh | Oral formulation of diaminophenothiazines and methods of making and using the same in the treatment and/or prevention of diseases |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU708682B2 (en) * | 1994-08-08 | 1999-08-12 | Albert Einstein College Of Medicine Of Yeshiva University | Methods for treating and/or preventing Alzheimer's disease using phenothiazines and/or thioxanthenes |
| GB9506197D0 (en) * | 1995-03-27 | 1995-05-17 | Hoffmann La Roche | Inhibition of tau-tau association. |
| JP2000344685A (ja) * | 1999-03-26 | 2000-12-12 | Bf Kenkyusho:Kk | アズールａ類似化合物によるアミロイドが蓄積する疾患の画像診断プローブおよびそれを含む画像診断用組成物 |
| GB0101049D0 (en) | 2001-01-15 | 2001-02-28 | Univ Aberdeen | Materials and methods relating to protein aggregation in neurodegenerative disease |
| GB0106953D0 (en) * | 2001-03-20 | 2001-05-09 | Univ Aberdeen | Neufofibrillary labels |
| GB0322756D0 (en) * | 2003-09-29 | 2003-10-29 | Univ Aberdeen | Methods of chemical synthesis |
| AU2004295148A1 (en) * | 2003-11-28 | 2005-06-16 | Photopharmica Limited | Developments in biologically active methylene blue derivatives (2) |
| CN101084204B (zh) | 2004-09-23 | 2012-12-05 | 卫思道制药有限公司 | 包括亚甲蓝(mtc)在内的二氨基吩噻嗪鎓化合物的化学合成和纯化方法 |
| EP3564223A1 (en) | 2004-09-23 | 2019-11-06 | WisTa Laboratories Ltd. | Methods of chemical synthesis and purification of diaminophenothiazinium compounds including methylthioninium chloride (mtc) |
-
2007
- 2007-03-28 EP EP14185157.6A patent/EP2853293B1/en active Active
- 2007-03-28 AU AU2007231127A patent/AU2007231127B2/en active Active
- 2007-03-28 CN CN2007800202730A patent/CN101460222B/zh active Active
- 2007-03-28 SI SI200731541T patent/SI2001556T1/sl unknown
- 2007-03-28 PT PT141851576T patent/PT2853293T/pt unknown
- 2007-03-28 SI SI200732008T patent/SI2853293T1/sl unknown
- 2007-03-28 EP EP07712962.5A patent/EP2001556B1/en active Active
- 2007-03-28 WO PCT/GB2007/001107 patent/WO2007110630A1/en active Application Filing
- 2007-03-28 DK DK14185157.6T patent/DK2853293T3/en active
- 2007-03-28 DK DK07712962.5T patent/DK2001556T3/da active
- 2007-03-28 CA CA2645919A patent/CA2645919C/en active Active
- 2007-03-28 CN CN201310514618.5A patent/CN103641794B/zh active Active
- 2007-03-28 PL PL07712962T patent/PL2001556T3/pl unknown
- 2007-03-28 PL PL14185157T patent/PL2853293T3/pl unknown
- 2007-03-28 JP JP2009502207A patent/JP5184507B2/ja active Active
- 2007-03-28 ES ES14185157.6T patent/ES2659030T3/es active Active
- 2007-03-28 ES ES07712962.5T patent/ES2525001T3/es active Active
- 2007-03-28 MY MYPI20083822A patent/MY162640A/en unknown
- 2007-03-28 MY MYPI2014003327A patent/MY172157A/en unknown
- 2007-03-28 PT PT77129625T patent/PT2001556E/pt unknown
-
2009
- 2009-01-14 HK HK09100375.6A patent/HK1121084A1/xx unknown
-
2014
- 2014-12-29 HR HRP20141261TT patent/HRP20141261T1/hr unknown
-
2015
- 2015-09-08 HK HK15108741.8A patent/HK1208000A1/xx unknown
-
2018
- 2018-02-02 HR HRP20180204TT patent/HRP20180204T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL2853293T3 (pl) | 2018-05-30 |
| EP2853293B1 (en) | 2017-11-22 |
| MY162640A (en) | 2017-06-30 |
| PL2001556T3 (pl) | 2015-03-31 |
| MY172157A (en) | 2019-11-15 |
| ES2525001T3 (es) | 2014-12-16 |
| CN101460222A (zh) | 2009-06-17 |
| DK2853293T3 (en) | 2018-01-22 |
| ES2659030T3 (es) | 2018-03-13 |
| JP5184507B2 (ja) | 2013-04-17 |
| AU2007231127B2 (en) | 2013-03-14 |
| EP2001556B1 (en) | 2014-10-01 |
| DK2001556T3 (da) | 2014-11-10 |
| CN103641794A (zh) | 2014-03-19 |
| HRP20180204T1 (hr) | 2018-03-09 |
| CN101460222B (zh) | 2013-12-04 |
| AU2007231127A1 (en) | 2007-10-04 |
| HK1121084A1 (en) | 2009-04-17 |
| EP2853293A1 (en) | 2015-04-01 |
| PT2001556E (pt) | 2014-12-09 |
| CN103641794B (zh) | 2016-09-21 |
| JP2009531405A (ja) | 2009-09-03 |
| PT2853293T (pt) | 2018-02-13 |
| CA2645919C (en) | 2016-05-31 |
| SI2853293T1 (sl) | 2018-03-30 |
| HK1208000A1 (en) | 2016-02-19 |
| CA2645919A1 (en) | 2007-10-04 |
| EP2001556A1 (en) | 2008-12-17 |
| HRP20141261T1 (en) | 2015-03-13 |
| WO2007110630A1 (en) | 2007-10-04 |
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