HUE045460T2 - Fenotiazin vegyületek enyhe kognitív zavar kezelésére - Google Patents
Fenotiazin vegyületek enyhe kognitív zavar kezeléséreInfo
- Publication number
- HUE045460T2 HUE045460T2 HUE08762390A HUE08762390A HUE045460T2 HU E045460 T2 HUE045460 T2 HU E045460T2 HU E08762390 A HUE08762390 A HU E08762390A HU E08762390 A HUE08762390 A HU E08762390A HU E045460 T2 HUE045460 T2 HU E045460T2
- Authority
- HU
- Hungary
- Prior art keywords
- cognitive impairment
- mild cognitive
- treating mild
- phenothiazine compounds
- phenothiazine
- Prior art date
Links
- 208000010877 cognitive disease Diseases 0.000 title 1
- 208000027061 mild cognitive impairment Diseases 0.000 title 1
- 125000001484 phenothiazinyl group Chemical class C1(=CC=CC=2SC3=CC=CC=C3NC12)* 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US94500607P | 2007-06-19 | 2007-06-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE045460T2 true HUE045460T2 (hu) | 2019-12-30 |
Family
ID=39943003
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE08762390A HUE045460T2 (hu) | 2007-06-19 | 2008-06-17 | Fenotiazin vegyületek enyhe kognitív zavar kezelésére |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US9211294B2 (hu) |
| EP (1) | EP2167095B1 (hu) |
| JP (1) | JP5725605B2 (hu) |
| CN (1) | CN101820884B (hu) |
| AU (1) | AU2008265045B2 (hu) |
| BR (1) | BRPI0813670A2 (hu) |
| CA (1) | CA2690746C (hu) |
| DK (1) | DK2167095T3 (hu) |
| ES (1) | ES2739546T3 (hu) |
| HR (1) | HRP20191513T1 (hu) |
| HU (1) | HUE045460T2 (hu) |
| MY (1) | MY177001A (hu) |
| PL (1) | PL2167095T3 (hu) |
| PT (1) | PT2167095T (hu) |
| SI (1) | SI2167095T1 (hu) |
| WO (1) | WO2008155533A2 (hu) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2013191T6 (en) | 2006-03-29 | 2019-04-23 | Wista Lab Ltd | 3,7-Diamino-10H-phenothiazine salts and their use |
| MY161656A (en) * | 2007-10-03 | 2017-04-28 | Wista Lab Ltd | Therapeutic use of diaminophenothiazines |
| CN102958525B (zh) | 2010-04-30 | 2017-05-24 | 普罗瑟塔抗病毒股份有限公司 | 抗病毒化合物 |
| RS55237B1 (sr) | 2011-02-11 | 2017-02-28 | Wis Ta Laboratories Ltd | Fenotiazin diaminijum soli i njihova primena |
| WO2012145567A1 (en) | 2011-04-20 | 2012-10-26 | Prosetta Antiviral Inc. | Antiviral compounds |
| US9523045B2 (en) * | 2013-01-30 | 2016-12-20 | Ecolab Usa Inc. | Hydrogen sulfide scavengers |
| US10304006B2 (en) * | 2013-02-15 | 2019-05-28 | The Charles Stark Draper Laboratory, Inc. | Method for integrating and fusing heterogeneous data types to perform predictive analysis |
| US10472340B2 (en) * | 2015-02-17 | 2019-11-12 | Arizona Board Of Regents On Behalf Of Arizona State University | Substituted phenothiazines as mitochondrial agents |
| US11065256B2 (en) | 2016-07-25 | 2021-07-20 | Wista Laboratories Ltd. | Administration and dosage of diaminophenothiazines |
| GB201614834D0 (en) * | 2016-09-01 | 2016-10-19 | Wista Lab Ltd | Treatment of dementia |
| IL280361B2 (en) | 2018-07-26 | 2024-07-01 | Wista Lab Ltd | Optimised dosage of diaminophenothiazines in populations |
| CA3134588A1 (en) * | 2019-04-10 | 2020-10-15 | Genting Taurx Diagnostic Centre Sdn Bhd | Adaptive neurological testing method |
| GB201909454D0 (en) | 2019-07-01 | 2019-08-14 | Wista Lab Ltd | Enhancers |
| GB201909493D0 (en) | 2019-07-01 | 2019-08-14 | Wista Lab Ltd | Therapeutic interactions |
| GB201909506D0 (en) | 2019-07-02 | 2019-08-14 | Wista Lab Ltd | Synaptopathies |
| EP4531863A1 (en) | 2022-05-31 | 2025-04-09 | WisTa Laboratories Ltd. | Treatment of neurodegenerative disorders utilising methylthioninium (mt)-containing compounds |
| WO2024184146A1 (en) | 2023-03-03 | 2024-09-12 | Wista Laboratories Ltd. | Diaminophenothiazine for the treatment of microvascular brain disease disease |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9506197D0 (en) * | 1995-03-27 | 1995-05-17 | Hoffmann La Roche | Inhibition of tau-tau association. |
| GB0017060D0 (en) * | 2000-07-11 | 2000-08-30 | Hunter Fleming Ltd | Production, stabilisation and use of reduced forms of pharmaceutical compounds |
| GB0101049D0 (en) * | 2001-01-15 | 2001-02-28 | Univ Aberdeen | Materials and methods relating to protein aggregation in neurodegenerative disease |
| AU2004226876A1 (en) * | 2003-04-03 | 2004-10-14 | Prana Biotechnology Ltd | Treatment of neurological conditions |
| US7790881B2 (en) * | 2004-09-23 | 2010-09-07 | Wista Laboratories Ltd. | Methods of chemical synthesis and purification of diaminophenothiazinium compounds including methylthioninium chloride (MTC) |
| HUE044355T2 (hu) * | 2004-09-23 | 2019-10-28 | Wista Lab Ltd | Eljárások diaminofenotiazínium vegyületek, többek között metiltionínium-klorid (MTC) kémiai szintézisére és tisztítására |
| WO2006091728A2 (en) * | 2005-02-24 | 2006-08-31 | The Trustees Of The University Of Pennsylvania | Microtubule stabilizing compounds and methods of their use |
| DK2004155T3 (en) | 2006-03-29 | 2018-04-30 | Wista Lab Ltd | PROTEIN AGGREGATION INHIBITORS |
| DK2013191T6 (en) | 2006-03-29 | 2019-04-23 | Wista Lab Ltd | 3,7-Diamino-10H-phenothiazine salts and their use |
| CN103641794B (zh) | 2006-03-29 | 2016-09-21 | 维斯塔实验室有限公司 | 锍化合物及其用途 |
| EP2457904B1 (en) * | 2006-07-11 | 2014-11-19 | Wista Laboratories Ltd. | Methods of synthesis and/or purification of diaminophenothiazinium compounds |
-
2008
- 2008-06-17 CA CA2690746A patent/CA2690746C/en active Active
- 2008-06-17 CN CN2008801031955A patent/CN101820884B/zh active Active
- 2008-06-17 ES ES08762390T patent/ES2739546T3/es active Active
- 2008-06-17 US US12/665,608 patent/US9211294B2/en active Active
- 2008-06-17 JP JP2010512761A patent/JP5725605B2/ja active Active
- 2008-06-17 MY MYPI20095255A patent/MY177001A/en unknown
- 2008-06-17 HU HUE08762390A patent/HUE045460T2/hu unknown
- 2008-06-17 BR BRPI0813670-0A2A patent/BRPI0813670A2/pt not_active Application Discontinuation
- 2008-06-17 WO PCT/GB2008/002066 patent/WO2008155533A2/en active Application Filing
- 2008-06-17 AU AU2008265045A patent/AU2008265045B2/en active Active
- 2008-06-17 HR HRP20191513 patent/HRP20191513T1/hr unknown
- 2008-06-17 DK DK08762390.6T patent/DK2167095T3/da active
- 2008-06-17 PL PL08762390T patent/PL2167095T3/pl unknown
- 2008-06-17 PT PT08762390T patent/PT2167095T/pt unknown
- 2008-06-17 EP EP08762390.6A patent/EP2167095B1/en active Active
- 2008-06-17 SI SI200832080T patent/SI2167095T1/sl unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI0813670A2 (pt) | 2014-12-30 |
| EP2167095A2 (en) | 2010-03-31 |
| US20100184752A1 (en) | 2010-07-22 |
| JP2010530403A (ja) | 2010-09-09 |
| AU2008265045A1 (en) | 2008-12-24 |
| JP5725605B2 (ja) | 2015-05-27 |
| CN101820884B (zh) | 2013-08-28 |
| US9211294B2 (en) | 2015-12-15 |
| DK2167095T3 (da) | 2019-07-29 |
| WO2008155533A2 (en) | 2008-12-24 |
| HRP20191513T1 (hr) | 2019-11-29 |
| CA2690746A1 (en) | 2008-12-24 |
| PT2167095T (pt) | 2019-08-06 |
| EP2167095B1 (en) | 2019-05-29 |
| CA2690746C (en) | 2018-01-02 |
| AU2008265045B2 (en) | 2014-02-27 |
| SI2167095T1 (sl) | 2019-09-30 |
| ES2739546T3 (es) | 2020-01-31 |
| MY177001A (en) | 2020-09-01 |
| PL2167095T3 (pl) | 2019-11-29 |
| CN101820884A (zh) | 2010-09-01 |
| WO2008155533A3 (en) | 2009-02-19 |
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