BRPI0813191B1 - Processo de sulfoxidação de compostos biologicamente ativos - Google Patents

Processo de sulfoxidação de compostos biologicamente ativos Download PDF

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Publication number
BRPI0813191B1
BRPI0813191B1 BRPI0813191-0A BRPI0813191A BRPI0813191B1 BR PI0813191 B1 BRPI0813191 B1 BR PI0813191B1 BR PI0813191 A BRPI0813191 A BR PI0813191A BR PI0813191 B1 BRPI0813191 B1 BR PI0813191B1
Authority
BR
Brazil
Prior art keywords
added
grams
oxaziridine
reaction
mol
Prior art date
Application number
BRPI0813191-0A
Other languages
English (en)
Portuguese (pt)
Inventor
Sudarshan Golakchandra Maikap
Dagesing Rajendra Mahale
Keshav Mukund Gurjar
Ramsing Mahesh Rajput
Sadashiv Prashant Gawari
Moreshwar Milind Gharpure
Ramanlal Satish Mehta
Original Assignee
Emcure Pharmaceuticals Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Emcure Pharmaceuticals Limited filed Critical Emcure Pharmaceuticals Limited
Publication of BRPI0813191A2 publication Critical patent/BRPI0813191A2/pt
Publication of BRPI0813191B1 publication Critical patent/BRPI0813191B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B45/00—Formation or introduction of functional groups containing sulfur
    • C07B45/04—Formation or introduction of functional groups containing sulfur of sulfonyl or sulfinyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B53/00—Asymmetric syntheses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00—Preparation of sulfones; Preparation of sulfoxides
    • C07C315/02—Preparation of sulfones; Preparation of sulfoxides by formation of sulfone or sulfoxide groups by oxidation of sulfides, or by formation of sulfone groups by oxidation of sulfoxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
BRPI0813191-0A 2007-06-15 2008-06-04 Processo de sulfoxidação de compostos biologicamente ativos BRPI0813191B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
IN1124/MUM/2007 2007-06-15
IN1124MU2007 2007-06-15
IN35/MUM/2008 2008-01-07
IN35MU2008 2008-01-07
PCT/IB2008/001423 WO2008152462A1 (en) 2007-06-15 2008-06-04 A process of sulfoxidation of biologically active compounds

Publications (2)

Publication Number Publication Date
BRPI0813191A2 BRPI0813191A2 (pt) 2014-12-23
BRPI0813191B1 true BRPI0813191B1 (pt) 2021-09-08

Family

ID=39790870

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0813191-0A BRPI0813191B1 (pt) 2007-06-15 2008-06-04 Processo de sulfoxidação de compostos biologicamente ativos

Country Status (5)

Country Link
KR (1) KR101432866B1 (ko)
BR (1) BRPI0813191B1 (ko)
EA (1) EA016297B1 (ko)
WO (1) WO2008152462A1 (ko)
ZA (1) ZA200908887B (ko)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009024863A2 (en) * 2007-06-26 2009-02-26 Actavis Group Ptc Ehf Process for the preparation of modafinil enantiomers
EP2534144B1 (en) * 2010-02-12 2014-09-03 Esteve Química, S.A. Preparation process of the sodium salt of Esomeprazole
CN102329302A (zh) * 2011-10-22 2012-01-25 刘强 一种埃索美拉唑及其盐的制备方法
CN102432412A (zh) * 2011-10-28 2012-05-02 成都欣捷高新技术开发有限公司 一种手性亚砜类质子泵抑制剂或其可药用盐的制备方法
EP2615083A1 (en) 2012-01-10 2013-07-17 Studiengesellschaft Kohle mbH Process for the asymmetric oxidation of organic compounds with peroxides in the presence of a chiral acid catalyst
CN102603621B (zh) * 2012-02-07 2013-09-04 成都苑东药业有限公司 一种新型手性亚砜化合物和以该化合物制备埃索美拉唑钠的方法
CN102924434B (zh) * 2012-10-18 2014-06-18 江苏诚信制药有限公司 一种右旋雷贝拉唑钠单水合物晶型及其制备方法
CN105294652A (zh) * 2012-10-25 2016-02-03 天津汉瑞药业有限公司 雷贝拉唑钠化合物
CN103113350A (zh) * 2013-02-27 2013-05-22 安徽省新星药物开发有限责任公司 R-雷贝拉唑钠水合物的新晶型及制备方法和应用
CN104327049B (zh) * 2014-09-27 2015-10-14 湖南五洲通药业有限责任公司 右旋雷贝拉唑钠单水合物晶体的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP960232A2 (en) * 1995-07-03 1998-02-28 Astra Ab A process for the optical purification of compounds
NZ530168A (en) * 2001-07-16 2004-08-27 Janssen Pharmaceutica Nv Improved process for preparing benzimidazole-type compounds

Also Published As

Publication number Publication date
ZA200908887B (en) 2011-02-23
EA201070021A1 (ru) 2010-06-30
KR101432866B1 (ko) 2014-08-26
WO2008152462A1 (en) 2008-12-18
KR20100020035A (ko) 2010-02-19
BRPI0813191A2 (pt) 2014-12-23
EA016297B1 (ru) 2012-03-30

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Legal Events

Date Code Title Description
B06T Formal requirements before examination [chapter 6.20 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 04/06/2008, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO.