BRPI0810670A2 - composições de tolperisona - Google Patents
composições de tolperisonaInfo
- Publication number
- BRPI0810670A2 BRPI0810670A2 BRPI0810670A BRPI0810670A BRPI0810670A2 BR PI0810670 A2 BRPI0810670 A2 BR PI0810670A2 BR PI0810670 A BRPI0810670 A BR PI0810670A BR PI0810670 A BRPI0810670 A BR PI0810670A BR PI0810670 A2 BRPI0810670 A2 BR PI0810670A2
- Authority
- BR
- Brazil
- Prior art keywords
- tolperisone
- compositions
- tolperisone compositions
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4453—Non condensed piperidines, e.g. piperocaine only substituted in position 1, e.g. propipocaine, diperodon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/145555—Hetero-N
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Diabetes (AREA)
- Psychiatry (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Hospice & Palliative Care (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT6582007 | 2007-04-26 | ||
AT0195307A AT505225A1 (de) | 2007-04-26 | 2007-11-29 | 0erfahren zur herstellung von hoch reinem 2,4'-dimethyl-3-piperidino-propiophenon (tolperison), dieses enthaltende pharmazeutische zusammensetzungen, sowie tolperison enthaltende wirkstoffformulierungen |
US2379908P | 2008-01-25 | 2008-01-25 | |
PCT/US2008/005281 WO2008133937A2 (en) | 2007-04-26 | 2008-04-24 | Compositions of tolperisone |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0810670A2 true BRPI0810670A2 (pt) | 2017-05-09 |
Family
ID=39944530
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0810670A BRPI0810670A2 (pt) | 2007-04-26 | 2008-04-24 | composições de tolperisona |
Country Status (13)
Country | Link |
---|---|
US (7) | US8372979B2 (pt) |
EP (2) | EP2146976A2 (pt) |
JP (2) | JP5377473B2 (pt) |
KR (2) | KR20100031095A (pt) |
CN (2) | CN101679329A (pt) |
AT (1) | AT505225A1 (pt) |
BR (1) | BRPI0810670A2 (pt) |
CA (2) | CA2685268C (pt) |
ES (1) | ES2587369T3 (pt) |
HU (1) | HUE028942T2 (pt) |
MX (2) | MX2009011543A (pt) |
RU (1) | RU2009143670A (pt) |
WO (2) | WO2008133937A2 (pt) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AT505225A1 (de) | 2007-04-26 | 2008-11-15 | Sanochemia Pharmazeutika Ag | 0erfahren zur herstellung von hoch reinem 2,4'-dimethyl-3-piperidino-propiophenon (tolperison), dieses enthaltende pharmazeutische zusammensetzungen, sowie tolperison enthaltende wirkstoffformulierungen |
HUP0700828A2 (en) * | 2007-12-20 | 2010-01-28 | Richter Gedeon Nyrt | Transdermal pharmaceutical compositions containing tolperisone alone and in combination |
US20100249423A1 (en) | 2009-03-09 | 2010-09-30 | Sanochemia Pharmazeutika Ag | Tolperisone controlled release tablet |
KR101156054B1 (ko) * | 2011-09-05 | 2012-06-20 | 주식회사 네비팜 | 안정한 에페리손 함유 서방성 의약조성물 |
AU2014251038A1 (en) | 2013-04-08 | 2015-11-26 | Dennis M. Brown | Therapeutic benefit of suboptimally administered chemical compounds |
CN107868065B (zh) * | 2017-10-19 | 2021-05-18 | 湖北美林药业有限公司 | 一种盐酸托哌酮化合物及其制备方法 |
US20200390754A1 (en) * | 2017-11-17 | 2020-12-17 | Neurana Pharmaceuticals, Inc. | Methods of administering tolperisone |
CN110412141A (zh) * | 2018-04-28 | 2019-11-05 | 人福普克药业(武汉)有限公司 | 一种测定盐酸金刚烷胺软胶囊残留溶剂异丙醇的方法 |
TR201820976A2 (tr) * | 2018-12-28 | 2020-07-21 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | Fi̇ngoli̇mod ve bi̇r spazmoli̇ti̇k i̇çeren farmasöti̇k kombi̇nasyonlar |
CN110845443B (zh) * | 2019-12-11 | 2023-09-05 | 嘉实(湖南)医药科技有限公司 | 一种制备高纯度盐酸托哌酮的方法 |
WO2021146425A1 (en) * | 2020-01-14 | 2021-07-22 | Neurana Pharmaceuticals, Inc. | Methods of treating acute muscle spasms |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5191315A (ja) * | 1975-02-06 | 1976-08-10 | Anteinaensantoruperizonshirotsupunoseizoho | |
JPS5340779A (en) | 1976-09-21 | 1978-04-13 | Nippon Kayaku Co Ltd | Optically active tolpertisone, their preparation and pharmaceuticals containting the same |
JPS607627B2 (ja) * | 1977-08-02 | 1985-02-26 | 旭化成株式会社 | ピペリジン誘導体の製造方法 |
JPS5430178A (en) | 1977-08-05 | 1979-03-06 | Asahi Chem Ind Co Ltd | Preparation of propiophenone derivative |
JPS5432480A (en) | 1977-08-19 | 1979-03-09 | Asahi Chem Ind Co Ltd | Novel preparation of piperidine derivatives |
JPS5436274A (en) | 1977-08-24 | 1979-03-16 | Asahi Chem Ind Co Ltd | Preparation of propiophenone derivative |
JPS6143108A (ja) | 1984-08-03 | 1986-03-01 | Nippon Shinyaku Co Ltd | 医薬品製剤及びその製造法 |
DK162986A (da) | 1985-04-12 | 1986-10-13 | Forest Laboratories | Terapeutisk middel i enhedsdosisform |
JPH0720866B2 (ja) | 1987-05-15 | 1995-03-08 | 三生製薬株式会社 | エペリゾン又はトルペリゾン或いはそれらの塩類含有経皮適用製剤 |
IL87710A (en) | 1987-09-18 | 1992-06-21 | Ciba Geigy Ag | Covered floating retard form for controlled release in gastric juice |
DE3803482A1 (de) | 1988-02-05 | 1989-08-17 | Lohmann Therapie Syst Lts | Schwimmfaehiges orales therapeutisches system |
JPH045283A (ja) | 1990-04-24 | 1992-01-09 | Toyo Pharma- Kk | アミノプロピオフェノン誘導体又はその塩の製造方法 |
EP0717988B1 (en) | 1993-08-20 | 2001-10-17 | Nippon Shinyaku Company, Limited | Gastric remaining preparation, swollen molding, and production process |
IT1282650B1 (it) | 1996-02-19 | 1998-03-31 | Jagotec Ag | Compressa farmaceutica,caratterizzata da elevato aumento di volume a contatto con liquidi biologici |
FR2784583B1 (fr) | 1998-10-16 | 2002-01-25 | Synthelabo | Composition pharmaceutique a residence gastrique et a liberation controlee |
AT409083B (de) | 1999-04-01 | 2002-05-27 | Sanochemia Pharmazeutika Ag | Pharmazeutische, tolperison enthaltende zubereitung zur oralen verabreichung |
US20060013876A1 (en) | 2002-06-26 | 2006-01-19 | Lohray Braj B | Novel floating dosage form |
KR100511492B1 (ko) | 2002-10-11 | 2005-08-31 | 주식회사 태평양 | 에페리손, 톨페리손 또는 그것들의 염을 포함하는경피흡수제제 |
AT413539B (de) | 2002-12-05 | 2006-03-15 | Sanochemia Pharmazeutika Ag | Verfahren zum herstellen von salzen des tolperison |
AT500144A1 (de) | 2004-03-05 | 2005-11-15 | Sanochemia Pharmazeutika Ag | Tolperison enthaltende, pharmazeutische zubereitung mit steuerbarer wirkstofffreisetzung zur oralen verabreichung |
US20060004050A1 (en) | 2004-07-02 | 2006-01-05 | Speicher Brian T | Compositions and methods for the prevention or treatment of pain and other nervous system disorders |
CA2598204C (en) * | 2004-11-09 | 2015-01-13 | Board Of Regents, The University Of Texas System | Stabilized hme composition with small drug particles |
DE102005014080B4 (de) | 2005-03-21 | 2007-11-22 | Birds Pharma Gmbh Berolina Innovative Research & Development Services | Additionssalze des Tolperison, Verfahren zu deren Herstellung, Verwendung derselben und diese enthaltende Arzneimittel |
TW200732292A (en) * | 2006-02-01 | 2007-09-01 | Shell Int Research | A method of treating an aldehyde mixture, use of the treated aldehyde, and an alcohol |
AT505225A1 (de) | 2007-04-26 | 2008-11-15 | Sanochemia Pharmazeutika Ag | 0erfahren zur herstellung von hoch reinem 2,4'-dimethyl-3-piperidino-propiophenon (tolperison), dieses enthaltende pharmazeutische zusammensetzungen, sowie tolperison enthaltende wirkstoffformulierungen |
HUP0700485A3 (en) | 2007-07-23 | 2010-01-28 | Richter Gedeon Nyrt | Pharmaceutical composition with controlled release containing tolperisone |
US20100249423A1 (en) | 2009-03-09 | 2010-09-30 | Sanochemia Pharmazeutika Ag | Tolperisone controlled release tablet |
-
2007
- 2007-11-29 AT AT0195307A patent/AT505225A1/de not_active Application Discontinuation
-
2008
- 2008-04-24 CA CA2685268A patent/CA2685268C/en active Active
- 2008-04-24 KR KR1020097023635A patent/KR20100031095A/ko not_active Application Discontinuation
- 2008-04-24 CA CA002683634A patent/CA2683634A1/en not_active Abandoned
- 2008-04-24 RU RU2009143670/04A patent/RU2009143670A/ru not_active Application Discontinuation
- 2008-04-24 CN CN200880013487A patent/CN101679329A/zh active Pending
- 2008-04-24 JP JP2010504375A patent/JP5377473B2/ja active Active
- 2008-04-24 KR KR1020097022857A patent/KR20100016123A/ko not_active Application Discontinuation
- 2008-04-24 EP EP08767427A patent/EP2146976A2/en not_active Ceased
- 2008-04-24 CN CN200880019279A patent/CN101754958A/zh active Pending
- 2008-04-24 MX MX2009011543A patent/MX2009011543A/es active IP Right Grant
- 2008-04-24 WO PCT/US2008/005281 patent/WO2008133937A2/en active Application Filing
- 2008-04-24 JP JP2010506253A patent/JP2010525060A/ja active Pending
- 2008-04-24 BR BRPI0810670A patent/BRPI0810670A2/pt not_active IP Right Cessation
- 2008-04-24 US US12/597,722 patent/US8372979B2/en active Active
- 2008-04-24 HU HUE08733252A patent/HUE028942T2/hu unknown
- 2008-04-24 US US12/597,664 patent/US9315480B2/en active Active
- 2008-04-24 WO PCT/AT2008/000149 patent/WO2008131469A2/de active Application Filing
- 2008-04-24 ES ES08733252.4T patent/ES2587369T3/es active Active
- 2008-04-24 EP EP08733252.4A patent/EP2150540B1/de active Active
- 2008-04-24 MX MX2009011544A patent/MX2009011544A/es not_active Application Discontinuation
- 2008-11-26 US US12/324,387 patent/US20090253743A1/en not_active Abandoned
-
2016
- 2016-03-11 US US15/068,006 patent/US9662317B2/en active Active
- 2016-08-01 US US15/225,182 patent/US9675598B2/en active Active
-
2017
- 2017-05-08 US US15/589,540 patent/US20170239228A1/en not_active Abandoned
-
2018
- 2018-07-26 US US16/046,633 patent/US20180344717A1/en not_active Abandoned
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application fees: application dismissed [chapter 8.6 patent gazette] | ||
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] | ||
B350 | Update of information on the portal [chapter 15.35 patent gazette] |