BRPI0807626A2 - Processo para a síntese de compostos de 2-aminotiazol como inibidores de quinase - Google Patents

Processo para a síntese de compostos de 2-aminotiazol como inibidores de quinase

Info

Publication number
BRPI0807626A2
BRPI0807626A2 BRPI0807626-0A2A BRPI0807626A BRPI0807626A2 BR PI0807626 A2 BRPI0807626 A2 BR PI0807626A2 BR PI0807626 A BRPI0807626 A BR PI0807626A BR PI0807626 A2 BRPI0807626 A2 BR PI0807626A2
Authority
BR
Brazil
Prior art keywords
aminotiazole
synthesis
compounds
kinase inhibitors
kinase
Prior art date
Application number
BRPI0807626-0A2A
Other languages
English (en)
Inventor
Alain Moussy
Philippe Reginault
Francois Bellamy
Anne Lermet
Original Assignee
Ab Science
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ab Science filed Critical Ab Science
Publication of BRPI0807626A2 publication Critical patent/BRPI0807626A2/pt
Publication of BRPI0807626B1 publication Critical patent/BRPI0807626B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
BRPI0807626-0A 2007-02-13 2008-02-13 Processo para a síntese de compostos de 2-aminotiazol como inibidores de quinase BRPI0807626B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US88958707P 2007-02-13 2007-02-13
US60/889,587 2007-02-13
PCT/EP2008/051704 WO2008098949A2 (en) 2007-02-13 2008-02-13 Process for the synthesis of 2-aminothiazole compounds as kinase inhibitors

Publications (2)

Publication Number Publication Date
BRPI0807626A2 true BRPI0807626A2 (pt) 2014-11-25
BRPI0807626B1 BRPI0807626B1 (pt) 2022-03-03

Family

ID=39332208

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0807626-0A BRPI0807626B1 (pt) 2007-02-13 2008-02-13 Processo para a síntese de compostos de 2-aminotiazol como inibidores de quinase

Country Status (23)

Country Link
US (3) US8153792B2 (pt)
EP (2) EP2366703B1 (pt)
JP (2) JP5568312B2 (pt)
KR (1) KR20090110851A (pt)
CN (2) CN101657446B (pt)
AR (1) AR065337A1 (pt)
AT (1) ATE515506T1 (pt)
AU (1) AU2008214679A1 (pt)
BR (1) BRPI0807626B1 (pt)
CA (2) CA2677586C (pt)
ES (2) ES2522169T3 (pt)
HR (2) HRP20110709T1 (pt)
IL (1) IL200320A0 (pt)
MA (1) MA31180B1 (pt)
MX (1) MX2009008665A (pt)
NZ (1) NZ578944A (pt)
PL (2) PL2118099T3 (pt)
RU (2) RU2456285C2 (pt)
SI (2) SI2118099T1 (pt)
TN (1) TN2009000342A1 (pt)
TW (1) TWI406862B (pt)
WO (1) WO2008098949A2 (pt)
ZA (1) ZA200905981B (pt)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2294344T3 (es) 2002-08-02 2008-04-01 Ab Science 2-(3-aminoaril)amino-4-aril-tiazoles y su utilizacion como inhibidores de c-kit.
US8450302B2 (en) 2002-08-02 2013-05-28 Ab Science 2-(3-aminoaryl) amino-4-aryl-thiazoles and their use as c-kit inhibitors
US20120302577A1 (en) 2010-01-28 2012-11-29 Ab Science Treatment of gist with masitinib
AR080096A1 (es) 2010-02-01 2012-03-14 Ab Science Tratamiento combinado de cancer de pancreas con gemcitabina y masitinib
AR080380A1 (es) 2010-03-09 2012-04-04 Ab Science Tratamiento de la demencia tipo alzheimer con masitinib
AR080933A1 (es) 2010-04-20 2012-05-16 Ab Science Tratamiento de esclerosis multiple con masitinib
TW201204719A (en) 2010-06-02 2012-02-01 Ab Science Treatment of rheumatoid arthritis with masitinib
WO2012059526A1 (en) 2010-11-05 2012-05-10 Ab Science Treatment of mastocytosis with masitinib
US10045978B2 (en) 2010-11-05 2018-08-14 Ab Science Treatment of mastocytosis with masitinib
WO2012104402A1 (en) * 2011-02-04 2012-08-09 Ab Science Treatment of severe persitent asthma with masitinib
WO2012136732A1 (en) 2011-04-08 2012-10-11 Ab Science Treatment of multiple myeloma with masitinib
SI2903616T1 (en) 2012-10-04 2018-02-28 Ab Science The use of masitinib in combination with gemcitabine for the treatment of a subgroup of patients suffering from foot-and-mouth disease
WO2015082496A1 (en) 2013-12-02 2015-06-11 Ab Science Use of masitinib for treatment of colorectal cancer
EP2886543A1 (en) 2013-12-18 2015-06-24 Sandoz Ag Crystalline form of mastinib mesylate
WO2015185958A1 (en) 2014-06-02 2015-12-10 Ab Science Use of an inhibitor of kinase activity, particularly masitinib, for treatment of prostate cancer
CN105585556A (zh) * 2014-11-13 2016-05-18 连云港杰瑞药业有限公司 一种伊马替尼的合成方法
CN106794179A (zh) * 2015-07-29 2017-05-31 苏州晶云药物科技有限公司 马赛替尼甲磺酸盐的新晶型及其制备方法
CA3000894A1 (en) 2015-10-05 2017-04-13 Ab Science Treatment of severe systemic mastocytosis with masitinib
EP3240538B1 (en) 2016-03-25 2021-09-29 AB Science Use of masitinib for treatment of an amyotrophic lateral sclerosis patient subpopulation
US10961235B2 (en) 2017-03-31 2021-03-30 Sandoz Ag Crystalline form of masitinib
US10696638B2 (en) 2017-12-26 2020-06-30 Industrial Technology Research Institute Compounds for inhibiting AGC kinase and pharmaceutical compositions comprising the same
EP4061371A1 (en) 2019-11-22 2022-09-28 AB Science Masitinib for the treatment of sickle cell disease
EP3831384A1 (en) 2019-12-02 2021-06-09 AB Science Use of masitinib for the treatment of eosinophilic asthma
CN115515590A (zh) 2020-02-20 2022-12-23 Ab科学有限公司 马赛替尼用于治疗多发性硬化患者亚群
CN115867278A (zh) 2020-04-10 2023-03-28 Ab科学有限公司 马赛替尼用于治疗2019冠状病毒病(covid-19)的用途
WO2022129410A1 (en) 2020-12-16 2022-06-23 Ab Science Masitinib for the treatment of alzheimer's disease
IL308088A (en) 2021-05-17 2023-12-01 Ab Science Mestitinib for the treatment of castrate-resistant prostate cancer
CN115850258A (zh) * 2022-12-27 2023-03-28 东北林业大学 一种马赛替尼的合成方法

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3299087A (en) * 1961-04-24 1967-01-17 Geigy Chem Corp Nu, nu'-bis-(thiazolyl)-phenylenediamines
WO1998052937A2 (en) * 1997-05-22 1998-11-26 G.D. Searle And Co. 4-aryl-3(5)-heteroaryl substituted pyrazoles as p38 kinase
CO4940418A1 (es) * 1997-07-18 2000-07-24 Novartis Ag Modificacion de cristal de un derivado de n-fenil-2- pirimidinamina, procesos para su fabricacion y su uso
GB9718913D0 (en) * 1997-09-05 1997-11-12 Glaxo Group Ltd Substituted oxindole derivatives
YU22400A (sh) * 1997-10-27 2003-08-29 Agouron Pharmaceuticals Inc. Supstituisana 4-amino-tiazol-2-i jedinjenja kao cdks inhibitori
US6114365A (en) * 1999-08-12 2000-09-05 Pharmacia & Upjohn S.P.A. Arylmethyl-carbonylamino-thiazole derivatives, process for their preparation, and their use as antitumor agents
ATE309241T1 (de) * 1999-09-10 2005-11-15 Merck & Co Inc Tyrosin kinase inhibitoren
ATE376182T1 (de) 2001-06-29 2007-11-15 Ab Science C-kit inhibitoren
EP1401429A2 (en) 2001-06-29 2004-03-31 AB Science Use of potent, selective and non toxic c-kit inhibitors for treating mastocytosis
JP2004530730A (ja) 2001-06-29 2004-10-07 アブ サイエンス 腫瘍の血管新生を治療するための強力で選択的かつ非毒性のｃ−ｋｉｔ阻害剤の使用法
JP2005502614A (ja) 2001-06-29 2005-01-27 アブ サイエンス 多発性硬化症（ｍｓ）を治療するためのチロシンキナーゼ阻害剤の使用方法
JP2004536097A (ja) 2001-06-29 2004-12-02 アブ サイエンス 自己免疫疾患を治療するためのチロシンキナーゼ阻害剤の使用法
US7700610B2 (en) 2001-06-29 2010-04-20 Ab Science Use of tyrosine kinase inhibitors for treating allergic diseases
US7678805B2 (en) 2001-06-29 2010-03-16 Ab Science Use of tyrosine kinase inhibitors for treating inflammatory bowel diseases (IBD)
EP1401411A2 (en) 2001-06-29 2004-03-31 AB Science Use of tyrosine kinase inhibitors for treating bone loss
JP2004537537A (ja) 2001-06-29 2004-12-16 アブ サイエンス 炎症性疾患を治療するためのチロシンキナーゼ阻害剤の使用法
US20030091974A1 (en) 2001-06-29 2003-05-15 Alain Moussy Method for screening compounds capable of depleting mast cells
US20040242612A1 (en) 2001-09-20 2004-12-02 Alain Moussy Use of tyrosine kinase inhibitors for promoting hair growth
DE60225590T2 (de) 2001-09-20 2008-09-25 Ab Science C-kithemmer zur behandlung von bakteriellen infektionen
JP2005511596A (ja) 2001-09-20 2005-04-28 アブ サイエンス ヒトの皮膚を白くし、且つメラノサイト機能不全関連疾病を治療するためのチロシンキナーゼ阻害剤の使用方法
WO2003072106A2 (en) 2002-02-27 2003-09-04 Ab Science Use of tyrosine kinase inhibitors for treating substance use disorders
WO2003072090A2 (en) 2002-02-27 2003-09-04 Ab Science Use of tyrosine kinase inhibitors for treating cns disorders
EP1507776B1 (en) * 2002-05-29 2007-02-28 Amgen Inc. 2-oxo-1,3,4-trihydroquinazolinyl derivatives for the treatment of cell proliferation-related disorders
ES2294344T3 (es) * 2002-08-02 2008-04-01 Ab Science 2-(3-aminoaril)amino-4-aril-tiazoles y su utilizacion como inhibidores de c-kit.
SE0202462D0 (sv) * 2002-08-14 2002-08-14 Astrazeneca Ab Novel use
WO2004072068A1 (en) * 2003-02-10 2004-08-26 Amgen Inc. Vanilloid receptor ligands and their use in treatments
JP2006519220A (ja) 2003-02-27 2006-08-24 アブ サイエンス 異なる型の肥満細胞症に適合可能なテイラーメイド治療方法
FR2854158B1 (fr) * 2003-04-25 2006-11-17 Sanofi Synthelabo Derives de 2-acylamino-4-phenylethiazole, leur preparation et leur application en therapeutique
MXPA06001098A (es) * 2003-07-29 2006-04-24 Irm Llc Compuestos y composiciones utiles como inhibidores de proteina cinasa.
EP1653934B1 (en) 2003-08-15 2008-05-14 AB Science Use of c-kit inhibitors for treating type ii diabetes
US7363881B2 (en) 2003-11-06 2008-04-29 Nova-Tech Engineering, Inc. Beak treatment with tongue protection
CN101456841B (zh) 2003-12-25 2012-01-25 日本新药株式会社 酰胺衍生物及医药品
US7650848B2 (en) * 2004-02-17 2010-01-26 University Of Florida Research Foundation, Inc. Surface topographies for non-toxic bioadhesion control
WO2005115385A1 (en) * 2004-05-24 2005-12-08 Ab Science Use of c-kit inhibitors for treating acne
TW200702876A (en) * 2005-07-04 2007-01-16 Avermedia Tech Inc Projector device capable of sychronously encoding audio and video to become AV sychronous paly file

Also Published As

Publication number Publication date
CN103342701B (zh) 2016-09-21
US8492545B2 (en) 2013-07-23
ZA200905981B (en) 2010-11-24
CN103342701A (zh) 2013-10-09
HRP20140986T1 (hr) 2014-11-21
JP2010518141A (ja) 2010-05-27
KR20090110851A (ko) 2009-10-22
EP2366703A1 (en) 2011-09-21
RU2456285C2 (ru) 2012-07-20
WO2008098949A2 (en) 2008-08-21
JP2013177437A (ja) 2013-09-09
NZ578944A (en) 2011-03-31
EP2118099A2 (en) 2009-11-18
US8153792B2 (en) 2012-04-10
AU2008214679A1 (en) 2008-08-21
ATE515506T1 (de) 2011-07-15
JP5568312B2 (ja) 2014-08-06
CA2970628C (en) 2019-08-27
SI2118099T1 (sl) 2011-11-30
PL2366703T3 (pl) 2015-02-27
CN101657446B (zh) 2013-05-15
CN101657446A (zh) 2010-02-24
BRPI0807626B1 (pt) 2022-03-03
WO2008098949A3 (en) 2008-10-02
TWI406862B (zh) 2013-09-01
TN2009000342A1 (en) 2010-12-31
ES2369617T3 (es) 2011-12-02
CA2970628A1 (en) 2008-08-21
RU2009132186A (ru) 2011-03-20
MX2009008665A (es) 2009-08-21
HRP20110709T1 (hr) 2011-11-30
AR065337A1 (es) 2009-06-03
CA2677586C (en) 2017-07-25
ES2522169T3 (es) 2014-11-13
PL2118099T3 (pl) 2011-12-30
EP2366703B1 (en) 2014-07-30
CA2677586A1 (en) 2008-08-21
TW200848419A (en) 2008-12-16
US20120196871A1 (en) 2012-08-02
RU2491286C1 (ru) 2013-08-27
JP5784073B2 (ja) 2015-09-24
IL200320A0 (en) 2010-04-29
US20130289045A1 (en) 2013-10-31
SI2366703T1 (sl) 2014-10-30
US8940894B2 (en) 2015-01-27
EP2118099B1 (en) 2011-07-06
MA31180B1 (fr) 2010-02-01
US20100121063A1 (en) 2010-05-13

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B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: A CLASSIFICACAO ANTERIOR ERA: C07D 417/04

Ipc: C07D 417/04 (2006.01), A61P 13/10 (2006.01), A61P

B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 13/02/2008, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO.