BRPI0910675A2 - Processo para preparação de intermediários de naftalen-2-ilpirazol-3-ona úteis na síntese dos inibidores de receptores sigma - Google Patents

Processo para preparação de intermediários de naftalen-2-ilpirazol-3-ona úteis na síntese dos inibidores de receptores sigma

Info

Publication number
BRPI0910675A2
BRPI0910675A2 BRPI0910675-8A BRPI0910675A BRPI0910675A2 BR PI0910675 A2 BRPI0910675 A2 BR PI0910675A2 BR PI0910675 A BRPI0910675 A BR PI0910675A BR PI0910675 A2 BRPI0910675 A2 BR PI0910675A2
Authority
BR
Brazil
Prior art keywords
ylpyrazol
synthesis
receptor inhibitors
intermediates useful
sigma receptor
Prior art date
Application number
BRPI0910675-8A
Other languages
English (en)
Inventor
Antoni Torrens Jover
Jordi Corbera Arjona
MARíA ROSA CUBERES-ALTISENT
Original Assignee
Esteve Labor Dr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Esteve Labor Dr filed Critical Esteve Labor Dr
Publication of BRPI0910675A2 publication Critical patent/BRPI0910675A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/18—One oxygen or sulfur atom
    • C07D231/20—One oxygen atom attached in position 3 or 5
BRPI0910675-8A 2008-04-25 2009-04-24 Processo para preparação de intermediários de naftalen-2-ilpirazol-3-ona úteis na síntese dos inibidores de receptores sigma BRPI0910675A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08384006A EP2112139A1 (en) 2008-04-25 2008-04-25 Process for the preparation of naphthalen-2-yl-pyrazol-3-one intermediates useful in the synthesis of sigma receptor inhibitors
PCT/EP2009/054981 WO2009130314A1 (en) 2008-04-25 2009-04-24 Process for the preparation of naphthalen-2-yl-pyrazol-3-one intermediates useful in the synthesis of sigma receptor inhibitors

Publications (1)

Publication Number Publication Date
BRPI0910675A2 true BRPI0910675A2 (pt) 2015-08-11

Family

ID=39717791

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0910675-8A BRPI0910675A2 (pt) 2008-04-25 2009-04-24 Processo para preparação de intermediários de naftalen-2-ilpirazol-3-ona úteis na síntese dos inibidores de receptores sigma

Country Status (17)

Country Link
US (1) US8329880B2 (pt)
EP (2) EP2112139A1 (pt)
JP (2) JP5781923B2 (pt)
KR (1) KR101641696B1 (pt)
CN (1) CN102066332B (pt)
AU (1) AU2009239889B2 (pt)
BR (1) BRPI0910675A2 (pt)
CA (1) CA2722250C (pt)
DK (1) DK2279175T3 (pt)
ES (1) ES2544759T3 (pt)
HK (1) HK1155436A1 (pt)
HU (1) HUE026759T2 (pt)
MX (1) MX2010011677A (pt)
PL (1) PL2279175T3 (pt)
PT (1) PT2279175E (pt)
RU (1) RU2509763C2 (pt)
WO (1) WO2009130314A1 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2116539A1 (en) 2008-04-25 2009-11-11 Laboratorios Del. Dr. Esteve, S.A. 1-aryl-3-aminoalkoxy-pyrazoles as sigma ligands enhancing analgesic effects of opioids and attenuating the dependency thereof
EP2353591A1 (en) 2010-02-04 2011-08-10 Laboratorios Del. Dr. Esteve, S.A. Sigma ligands for potentiating the analgesic effect of opioids and opiates in post-operative pain and attenuating the dependency thereof
EP2353598A1 (en) 2010-02-04 2011-08-10 Laboratorios Del. Dr. Esteve, S.A. Sigma ligands for use in the prevention and/or treatment of postoperative pain
EP2388005A1 (en) 2010-05-21 2011-11-23 Laboratorios Del. Dr. Esteve, S.A. Sigma ligands for the prevention and/or treatment of emesis induced by chemotherapy or radiotherapy
EP2418192A1 (en) 2010-07-30 2012-02-15 Esteve Química, S.A. Intermediates for the preparation of 1-aryl-pyrazol-3-one compounds useful as sigma receptors inhibitors
EP2415471A1 (en) 2010-08-03 2012-02-08 Laboratorios Del. Dr. Esteve, S.A. Use of sigma ligands in opioid-induced hyperalgesia
KR101306958B1 (ko) * 2010-11-08 2013-09-10 건국대학교 산학협력단 세포사멸 유도 활성을 갖는 트리메톡시페닐-4,5-디하이드로-1ｈ-피라졸-3-일-나프탈렌-2-올 유도체
EP2524694A1 (en) 2011-05-19 2012-11-21 Laboratorios Del. Dr. Esteve, S.A. Use of sigma ligands in diabetes type-2 associated pain
EP3082782A1 (en) 2013-12-17 2016-10-26 Laboratorios Del. Dr. Esteve, S.A. SEROTONIN-NOREPINEPHRINE REUPTAKE INHIBITORS (SNRIs) AND SIGMA RECEPTOR LIGANDS COMBINATIONS

Family Cites Families (15)

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Publication number Priority date Publication date Assignee Title
US2908677A (en) * 1955-03-30 1959-10-13 Eastman Kodak Co Nickel and cobalt complexes of pyrazolone monoazo compounds
NL125658C (pt) * 1964-02-03
CH471199A (de) * 1965-07-06 1969-04-15 Sandoz Ag Verfahren zur Herstellung metallhaltiger Azofarbstoffe
DE2313722B2 (de) * 1973-03-20 1977-08-11 Bayer Ag, 5090 Leverkusen Chromischkomplex-farbstoffe und ihre verwendung zum faerben und bedrucken von stickstoffhaltigen fasermaterialien
DE2347015C2 (de) * 1973-09-14 1985-12-12 Schering AG, 1000 Berlin und 4709 Bergkamen Neue Pyrazolyloxyessigsäurederivate, Verfahren zu ihrer Herstellung und diese enthaltende Mittel
IT1005472B (it) * 1974-02-15 1976-08-20 Montedison Spa Procedimento per la preparazione del 2,5, dimetil 3,2h, furanone
CA1121651A (en) 1978-07-27 1982-04-13 Chi-Kuen Shu 2,5-dialkyl dihydrofuranones and 2,4,5-trialkyl dihydrofuranones, mixtures of same and organoleptic uses thereof
US4207392A (en) * 1978-10-30 1980-06-10 Eastman Kodak Company Heat developable and stabilizable photographic materials and process
US4234616A (en) 1979-08-03 1980-11-18 International Flavors & Fragrances Inc. Flavoring with mixtures of 2,5-dialkyl dihydrofuranones and 2,4,5-trialkyl dihydrofuranones
EP0054002B1 (de) * 1980-12-10 1985-08-21 Ciba-Geigy Ag Verfahren zur Herstellung von 3-Pyrazolidinonen und ihre Verwendung in photographischen Entwicklerlösungen
JPH1036259A (ja) 1996-04-11 1998-02-10 Kikkoman Corp 白内障の予防または治療薬剤
US7091257B2 (en) * 1999-07-27 2006-08-15 Alcatel Radiation-curable composition with simultaneous color formation during cure
US6965019B2 (en) * 2000-04-03 2005-11-15 Sun Chemical Corporation Mono-and bis-hydrazone pigments
AU2005276590B2 (en) 2004-08-27 2011-05-19 Laboratorios Del Dr. Esteve, S.A. Sigma receptor inhibitors
JP2009528315A (ja) 2006-03-01 2009-08-06 ラボラトリオス・デル・ドクトル・エステベ・ソシエダッド・アノニマ シグマ受容体阻害剤としてのピラゾール誘導体

Also Published As

Publication number Publication date
CA2722250A1 (en) 2009-10-29
MX2010011677A (es) 2010-11-25
US20110071282A1 (en) 2011-03-24
EP2112139A1 (en) 2009-10-28
PT2279175E (pt) 2015-08-28
WO2009130314A1 (en) 2009-10-29
JP5781923B2 (ja) 2015-09-24
US8329880B2 (en) 2012-12-11
AU2009239889A1 (en) 2009-10-29
JP2011518808A (ja) 2011-06-30
EP2279175A1 (en) 2011-02-02
PL2279175T3 (pl) 2015-10-30
RU2509763C2 (ru) 2014-03-20
DK2279175T3 (en) 2015-08-10
RU2010147938A (ru) 2012-05-27
KR101641696B1 (ko) 2016-07-22
CA2722250C (en) 2016-07-26
ES2544759T3 (es) 2015-09-03
HUE026759T2 (en) 2016-07-28
AU2009239889B2 (en) 2014-02-13
KR20110017367A (ko) 2011-02-21
CN102066332B (zh) 2016-10-26
CN102066332A (zh) 2011-05-18
HK1155436A1 (en) 2012-05-18
EP2279175B1 (en) 2015-05-13
JP2014237654A (ja) 2014-12-18

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 11A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2563 DE 2020-02-18