BRPI0715823A2 - sistema de detecÇço àtica compacto - Google Patents

sistema de detecÇço àtica compacto Download PDF

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Publication number
BRPI0715823A2
BRPI0715823A2 BRPI0715823-8A BRPI0715823A BRPI0715823A2 BR PI0715823 A2 BRPI0715823 A2 BR PI0715823A2 BR PI0715823 A BRPI0715823 A BR PI0715823A BR PI0715823 A2 BRPI0715823 A2 BR PI0715823A2
Authority
BR
Brazil
Prior art keywords
light
detection system
line
filter
sample
Prior art date
Application number
BRPI0715823-8A
Other languages
English (en)
Portuguese (pt)
Inventor
Pavel Neuzil
Juergen Pipper
Lukas Novak
Original Assignee
Agency Science Tech & Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agency Science Tech & Res filed Critical Agency Science Tech & Res
Publication of BRPI0715823A2 publication Critical patent/BRPI0715823A2/pt

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/14—Process control and prevention of errors
    • B01L2200/143—Quality control, feedback systems
    • B01L2200/147—Employing temperature sensors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B01L2300/1827—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using resistive heater
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Rigid containers without fluid transport within
    • B01L3/5088—Rigid containers without fluid transport within confining liquids at a location by surface tension, e.g. virtual wells on plates, wires
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N2021/6417—Spectrofluorimetric devices
    • G01N2021/6419—Excitation at two or more wavelengths
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N2021/6417—Spectrofluorimetric devices
    • G01N2021/6421—Measuring at two or more wavelengths
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
    • G01N2021/6441—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks with two or more labels
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N21/0332—Cuvette constructions with temperature control
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/76—Chemiluminescence; Bioluminescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/76—Chemiluminescence; Bioluminescence
    • G01N21/763—Bioluminescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/02—Mechanical
    • G01N2201/022—Casings
    • G01N2201/0221—Portable; cableless; compact; hand-held
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/062—LED's
    • G01N2201/0625—Modulated LED
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/062—LED's
    • G01N2201/0627—Use of several LED's for spectral resolution
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/069—Supply of sources
    • G01N2201/0693—Battery powered circuitry

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Clinical Laboratory Science (AREA)
  • Optics & Photonics (AREA)
  • Molecular Biology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
BRPI0715823-8A 2006-08-24 2007-08-24 sistema de detecÇço àtica compacto BRPI0715823A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US83967806P 2006-08-24 2006-08-24
US60/839,678 2006-08-24
PCT/SG2007/000272 WO2008024080A1 (en) 2006-08-24 2007-08-24 Compact optical detection system

Publications (1)

Publication Number Publication Date
BRPI0715823A2 true BRPI0715823A2 (pt) 2013-07-16

Family

ID=39107075

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0715823-8A BRPI0715823A2 (pt) 2006-08-24 2007-08-24 sistema de detecÇço àtica compacto

Country Status (6)

Country Link
US (1) US20100227386A1 (https=)
EP (1) EP2054714A4 (https=)
JP (1) JP5256201B2 (https=)
CN (1) CN101542273B (https=)
BR (1) BRPI0715823A2 (https=)
WO (1) WO2008024080A1 (https=)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2716575C (en) * 2007-02-23 2015-09-29 Ese Embedded System Engineering Gmbh Optical measuring instrument
US8280484B2 (en) 2007-12-18 2012-10-02 The Invention Science Fund I, Llc System, devices, and methods for detecting occlusions in a biological subject
US9672471B2 (en) 2007-12-18 2017-06-06 Gearbox Llc Systems, devices, and methods for detecting occlusions in a biological subject including spectral learning
JP2009300356A (ja) * 2008-06-17 2009-12-24 Shimadzu Corp 蛍光測定装置
US8524490B2 (en) 2008-09-18 2013-09-03 X-Bar Diagnostic Systems, Inc. Fully automated portable DNA detection system
AU2010239272B2 (en) * 2009-04-21 2015-09-17 The University Of Utah Research Foundation Light-emitting dye for intraoperative imaging or sentinel lymph node biopsy
EP2301666B1 (en) * 2009-09-09 2021-06-30 Cole-Parmer Ltd. Optical system for multiple reactions
US8269193B2 (en) * 2010-03-31 2012-09-18 Ecolab Usa Inc. Handheld fluorometer and method of use
EP3358387A1 (en) 2010-08-27 2018-08-08 The Board of Trustees of The Leland Stanford Junior University Microscopy imaging device with advanced imaging properties
KR20120020528A (ko) * 2010-08-30 2012-03-08 삼성전자주식회사 중합효소 연쇄반응 장치
EP2618154B1 (en) * 2010-09-17 2016-12-14 Tohoku University Method for determining effectiveness of medicine containing antibody as component
FR2972260B1 (fr) * 2011-03-04 2014-02-21 Centre Nat Rech Scient Fluorimetre submersible
JP6009841B2 (ja) * 2011-07-12 2016-10-19 オリンパス株式会社 光学的観察装置
FR2980577B1 (fr) * 2011-09-26 2013-09-20 Biomerieux Sa Systeme de detection et/ou de quantification in vitro par fluorimetrie
US10196681B2 (en) 2011-10-06 2019-02-05 Sequenom, Inc. Methods and processes for non-invasive assessment of genetic variations
CN103134780B (zh) * 2011-12-01 2015-12-09 中国科学院大连化学物理研究所 一种紧贴式激发光路的发光二极管诱导荧光检测器
EP2605001A1 (en) * 2011-12-15 2013-06-19 Hain Lifescience GmbH A device and method for optically measuring fluorescence of nucleic acids in test samples and use of the device and method
GB2500177A (en) * 2012-03-07 2013-09-18 Valeport Ltd Fluorometer with beamsplitter
KR101411428B1 (ko) * 2012-07-12 2014-06-24 한국과학기술원 집광식 휴대용 형광 검출 시스템
JP2014071083A (ja) * 2012-10-01 2014-04-21 Ushio Inc 蛍光光度計
JP6011367B2 (ja) * 2013-01-28 2016-10-19 ウシオ電機株式会社 蛍光光度計及び蛍光光度計用試料容器
CN103091298A (zh) * 2013-02-01 2013-05-08 厦门大学 一种实时荧光定量pcr检测系统
EP4513175A3 (en) 2013-02-22 2025-05-07 Life Technologies Corporation Optical systems and methods for biological analysis
US20140273181A1 (en) 2013-03-15 2014-09-18 Biofire Diagnostics, Inc. Compact optical system for substantially simultaneous monitoring of samples in a sample array
US20140322816A1 (en) * 2013-04-27 2014-10-30 Jeffrey Haas Portable explosive or drug detection system
DE102014108144B4 (de) * 2014-06-10 2015-12-31 Kist Europe-Korea Institute of Science and Technologie Europe Forschungsgesellschaft mbh Verfahren zum Betreiben eines Echtzeit-Polymerase-Kettenreaktionssystems (PCR) sowie eine Vorrichtung zum Betreiben des Verfahrens.
US20170247745A1 (en) * 2014-09-12 2017-08-31 Click Diagnostics, Inc. Multiplex optical detection
DE102014221734A1 (de) * 2014-10-24 2016-04-28 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Messvorrichtung und System zur Schmelzkurvenanalyse eines DNA Microarrays, sowie Verwendung eines Fluoreszenzdetektorarrays zur Analyse
SG11201806647VA (en) * 2016-03-15 2018-09-27 Dots Tech Corp Systems and methods for allergen detection
US10450603B2 (en) * 2016-09-12 2019-10-22 Delta Electronics Int'l (Singapore) Pte Ltd Fluorescence detection device
CN107964507B (zh) * 2016-10-18 2022-09-27 财团法人工业技术研究院 热对流聚合酶连锁反应装置及其光学检测方法
CN108072672B (zh) * 2017-12-14 2021-03-02 清华大学 一种烧蚀结构形貌及产物的在线监测装置及其监测方法
CN111742078B (zh) * 2017-12-21 2023-07-04 埃科莱布美国股份有限公司 无荧光的经涂黑光学组件
CN108195813B (zh) * 2018-01-24 2021-03-02 长春中医药大学 一种棕榈油纯度检测方法
IL277170B2 (en) * 2018-03-23 2025-09-01 Nippon Sheet Glass Co Ltd Reaction processing facility
WO2020028766A1 (en) * 2018-08-02 2020-02-06 The Charles Stark Draper Laboratory, Inc. Fluorescence lifetime well array reader and actuator
CN109470672A (zh) * 2018-12-06 2019-03-15 大连海事大学 多光强激发检测单个微藻细胞活性的装置与方法
JP2022530323A (ja) 2019-04-28 2022-06-29 ビスビュー メディカル，インコーポレイテッド デジタル検出能力および無線接続性を有する分子診断デバイス
CN110132969A (zh) * 2019-05-28 2019-08-16 怀光智能科技（武汉）有限公司 一种便携式病理玻片扫描仪及系统
CN110272822B (zh) * 2019-06-06 2021-10-26 上海交通大学 一种基因扩增实时荧光定量检测装置及检测方法
US11740177B2 (en) 2020-09-18 2023-08-29 Salvus, Llc Interferometric detection and quantification system and methods of use in aquatics
US11994504B2 (en) 2020-09-18 2024-05-28 Salvus, Llc Interferometric detection and quantification system and methods of use in food processing and food supply chain
US12399172B2 (en) 2020-09-18 2025-08-26 Salvus, Llc Interferometric detection and quantification system and methods of use in healthcare
WO2022126899A1 (zh) * 2020-12-14 2022-06-23 苏州先达基因科技有限公司 一种便携式荧光检测装置
CN117120862A (zh) * 2021-03-31 2023-11-24 住友电气工业株式会社 金刚石光磁传感器以及金刚石光磁传感器系统
WO2023280305A1 (en) * 2021-07-08 2023-01-12 Ixensor Co., Ltd. System and method to perform quantitative polymerase chain reaction
CN115753698A (zh) * 2021-09-02 2023-03-07 安徽皖仪科技股份有限公司 一种用于pcr荧光检测扫描头的光学系统
EP4419893A4 (en) * 2021-10-20 2025-08-06 Bio Rad Laboratories Inc FLUORESCENCE DETECTION SYSTEM

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3925018A (en) * 1973-06-08 1975-12-09 Technicon Instr Method and apparatus for quantitative analysis utilizing particulate reagent material
US5656493A (en) * 1985-03-28 1997-08-12 The Perkin-Elmer Corporation System for automated performance of the polymerase chain reaction
EP0687356B1 (en) * 1993-03-05 1998-05-13 Gersan Establishment Distinguishing natural from synthetic diamond
US5856493A (en) * 1995-02-06 1999-01-05 Smithkline Beecham Corporation Process for making novel form of paroxeting hydrochloride anhydrate
US5943129A (en) * 1997-08-07 1999-08-24 Cambridge Research & Instrumentation Inc. Fluorescence imaging system
WO2001004608A1 (en) * 1999-07-07 2001-01-18 Ljl Biosystems, Inc. Light detection device
US6369893B1 (en) * 1998-05-19 2002-04-09 Cepheid Multi-channel optical detection system
US6261848B1 (en) * 1998-05-08 2001-07-17 The Johns Hopkins University Miniature immuno-optical rapid analyte sensor platform
US6818437B1 (en) * 1998-05-16 2004-11-16 Applera Corporation Instrument for monitoring polymerase chain reaction of DNA
US6490030B1 (en) * 1999-01-18 2002-12-03 Verification Technologies, Inc. Portable product authentication device
US7410793B2 (en) * 1999-05-17 2008-08-12 Applera Corporation Optical instrument including excitation source
US6403037B1 (en) * 2000-02-04 2002-06-11 Cepheid Reaction vessel and temperature control system
JP3999479B2 (ja) * 2001-07-10 2007-10-31 オリンパス株式会社 光学装置
GB0209329D0 (en) * 2002-04-24 2002-06-05 Imp College Innovations Ltd A device
US20030219754A1 (en) * 2002-05-23 2003-11-27 Oleksy Jerome E. Fluorescence polarization detection of nucleic acids
JP4475923B2 (ja) * 2003-01-14 2010-06-09 株式会社モリタ製作所 診断用撮影器
US7148043B2 (en) * 2003-05-08 2006-12-12 Bio-Rad Laboratories, Inc. Systems and methods for fluorescence detection with a movable detection module
US7799557B2 (en) * 2003-12-10 2010-09-21 Samsung Electronics Co., Ltd. Polymerase chain reaction (PCR) module and multiple PCR system using the same
US7767439B2 (en) * 2003-12-10 2010-08-03 Samsung Electronics Co., Ltd. Real-time PCR monitoring apparatus and method
JP2005345378A (ja) * 2004-06-04 2005-12-15 Nippon Sheet Glass Co Ltd 光検出装置
US8053214B2 (en) * 2004-09-09 2011-11-08 Microfluidic Systems, Inc. Apparatus and method of extracting and optically analyzing an analyte from a fluid-based sample
US7820428B2 (en) * 2006-06-29 2010-10-26 General Electric Company Portable light generation and detection system

Also Published As

Publication number Publication date
US20100227386A1 (en) 2010-09-09
EP2054714A1 (en) 2009-05-06
JP5256201B2 (ja) 2013-08-07
JP2010501851A (ja) 2010-01-21
CN101542273B (zh) 2011-01-26
EP2054714A4 (en) 2012-03-14
CN101542273A (zh) 2009-09-23
WO2008024080A1 (en) 2008-02-28

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Legal Events

Date Code Title Description
B07A Technical examination (opinion): publication of technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

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