BRPI0709018A2 - leitora de fluorescência - Google Patents
leitora de fluorescência Download PDFInfo
- Publication number
- BRPI0709018A2 BRPI0709018A2 BRPI0709018-8A BRPI0709018A BRPI0709018A2 BR PI0709018 A2 BRPI0709018 A2 BR PI0709018A2 BR PI0709018 A BRPI0709018 A BR PI0709018A BR PI0709018 A2 BRPI0709018 A2 BR PI0709018A2
- Authority
- BR
- Brazil
- Prior art keywords
- substrate
- fluorescence reader
- light
- reader according
- emitted
- Prior art date
Links
- 239000000758 substrate Substances 0.000 claims abstract description 173
- 230000003287 optical effect Effects 0.000 claims abstract description 45
- 206010024769 Local reaction Diseases 0.000 claims abstract description 32
- 230000001629 suppression Effects 0.000 claims abstract description 30
- 239000000463 material Substances 0.000 claims description 23
- 238000003556 assay Methods 0.000 claims description 17
- 238000001514 detection method Methods 0.000 claims description 16
- 230000003595 spectral effect Effects 0.000 claims description 11
- 230000005284 excitation Effects 0.000 claims description 9
- 238000001914 filtration Methods 0.000 claims description 8
- 230000000717 retained effect Effects 0.000 claims description 8
- 230000001965 increasing effect Effects 0.000 claims description 7
- 230000005540 biological transmission Effects 0.000 claims description 5
- 230000010287 polarization Effects 0.000 claims description 5
- 238000013461 design Methods 0.000 claims description 4
- 238000005259 measurement Methods 0.000 claims description 4
- 238000010257 thawing Methods 0.000 claims 1
- 238000012360 testing method Methods 0.000 abstract description 6
- 239000000523 sample Substances 0.000 description 45
- 239000012491 analyte Substances 0.000 description 6
- 238000006243 chemical reaction Methods 0.000 description 5
- 230000005855 radiation Effects 0.000 description 5
- 229920000642 polymer Polymers 0.000 description 4
- 230000005670 electromagnetic radiation Effects 0.000 description 3
- 230000002708 enhancing effect Effects 0.000 description 3
- 238000005286 illumination Methods 0.000 description 3
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 2
- 230000001427 coherent effect Effects 0.000 description 2
- 239000000975 dye Substances 0.000 description 2
- 238000002866 fluorescence resonance energy transfer Methods 0.000 description 2
- MURGITYSBWUQTI-UHFFFAOYSA-N fluorescin Chemical compound OC(=O)C1=CC=CC=C1C1C2=CC=C(O)C=C2OC2=CC(O)=CC=C21 MURGITYSBWUQTI-UHFFFAOYSA-N 0.000 description 2
- 239000011521 glass Substances 0.000 description 2
- 238000001746 injection moulding Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 229910052710 silicon Inorganic materials 0.000 description 2
- 239000010703 silicon Substances 0.000 description 2
- 238000002834 transmittance Methods 0.000 description 2
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 description 1
- 239000004593 Epoxy Substances 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 238000002835 absorbance Methods 0.000 description 1
- 238000005452 bending Methods 0.000 description 1
- 238000003271 compound fluorescence assay Methods 0.000 description 1
- 229920001577 copolymer Polymers 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 229910003460 diamond Inorganic materials 0.000 description 1
- 239000010432 diamond Substances 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000000609 electron-beam lithography Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000001506 fluorescence spectroscopy Methods 0.000 description 1
- 230000014509 gene expression Effects 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 229940127121 immunoconjugate Drugs 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000005459 micromachining Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 239000002159 nanocrystal Substances 0.000 description 1
- 102000039446 nucleic acids Human genes 0.000 description 1
- 108020004707 nucleic acids Proteins 0.000 description 1
- 150000007523 nucleic acids Chemical class 0.000 description 1
- 230000037361 pathway Effects 0.000 description 1
- 229920000307 polymer substrate Polymers 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 229920002635 polyurethane Polymers 0.000 description 1
- 239000004814 polyurethane Substances 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000010076 replication Effects 0.000 description 1
- 230000003362 replicative effect Effects 0.000 description 1
- 239000004065 semiconductor Substances 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- 229920001169 thermoplastic Polymers 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N2021/6463—Optics
- G01N2021/6465—Angular discrimination
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Optics & Photonics (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0600642A SE529711C2 (sv) | 2006-03-22 | 2006-03-22 | Fluorescensläsare |
SE0600642-3 | 2006-03-22 | ||
PCT/SE2007/000275 WO2007108752A1 (fr) | 2006-03-22 | 2007-03-21 | Lecteur de fluorescence |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0709018A2 true BRPI0709018A2 (pt) | 2011-06-21 |
Family
ID=38522714
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0709018-8A BRPI0709018A2 (pt) | 2006-03-22 | 2007-03-21 | leitora de fluorescência |
Country Status (8)
Country | Link |
---|---|
US (2) | US8691153B2 (fr) |
EP (1) | EP1996922B1 (fr) |
JP (1) | JP5705432B2 (fr) |
CN (2) | CN102636469B (fr) |
AU (1) | AU2007227809B2 (fr) |
BR (1) | BRPI0709018A2 (fr) |
SE (1) | SE529711C2 (fr) |
WO (1) | WO2007108752A1 (fr) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE529711C2 (sv) * | 2006-03-22 | 2007-11-06 | Aamic Ab | Fluorescensläsare |
EP2694967A4 (fr) | 2011-04-06 | 2014-10-29 | Ortho Clinical Diagnostics Inc | Dispositif d'analyse ayant des saillies en forme de losange |
US8605283B2 (en) * | 2011-05-05 | 2013-12-10 | Emd Millipore Corporation | Apparatus and method for increasing collection efficiency in capillary based flowcytometry |
US9642568B2 (en) * | 2011-09-06 | 2017-05-09 | Medtronic Minimed, Inc. | Orthogonally redundant sensor systems and methods |
WO2013109821A1 (fr) | 2012-01-20 | 2013-07-25 | Ortho-Clinical Diagnostics, Inc. | Dispositif d'essai ayant un multiplexage |
CA2802645C (fr) | 2012-01-20 | 2020-08-11 | Ortho-Clinical Diagnostics, Inc. | Dispositif d'essai a taille d'echantillon controlable |
US8895293B2 (en) | 2012-01-20 | 2014-11-25 | Ortho-Clinical Diagnostics, Inc. | Assay device having uniform flow around corners |
EP2618153B1 (fr) | 2012-01-20 | 2015-03-18 | Ortho-Clinical Diagnostics, Inc. | Régulation d'écoulement de fluide à travers un dispositif de dosage |
US20130189672A1 (en) | 2012-01-20 | 2013-07-25 | Ortho-Clinical Diagnostics, Inc. | Assay Device Having Multiple Reagent Cells |
EP2888287A4 (fr) | 2012-08-21 | 2016-04-20 | Ortho Clinical Diagnostics Inc | Anticorps dirigés contre des haptènes de palipéridone et leur utilisation |
TR201910347T4 (tr) | 2012-08-21 | 2019-07-22 | Janssen Pharmaceutica Nv | Olanzapin haptenlerine yönelik antikorlar ve bunların kullanımı. |
CN108517014A (zh) | 2012-08-21 | 2018-09-11 | 詹森药业有限公司 | 利培酮半抗原的抗体及其用途 |
CN104736561B (zh) | 2012-08-21 | 2018-06-12 | 詹森药业有限公司 | 帕潘立酮的抗体及其用途 |
AU2013305879B2 (en) | 2012-08-21 | 2017-10-12 | Saladax Biomedical Inc. | Antibodies to aripiprazole and use thereof |
JP6339569B2 (ja) | 2012-08-21 | 2018-06-06 | ヤンセン ファーマシューティカ エヌ.ベー. | リスペリドンへの抗体及びその使用 |
EP2888234B1 (fr) | 2012-08-21 | 2017-12-06 | Janssen Pharmaceutica NV | Haptènes d'aripiprazole et leur utilisation dans des dosages immunologiques |
CN104736567B (zh) | 2012-08-21 | 2019-09-03 | 詹森药业有限公司 | 阿立哌唑半抗原的抗体及其用途 |
AU2013305907B2 (en) | 2012-08-21 | 2018-01-18 | Saladax Biomedical Inc. | Antibodies to quetiapine and use thereof |
CA2882596C (fr) | 2012-08-21 | 2019-05-14 | Ortho-Clinical Diagnostics, Inc. | Anticorps diriges contre l'olanzapine et leur utilisation |
CA2882597C (fr) | 2012-08-21 | 2020-04-14 | Ortho-Clinical Diagnostics, Inc. | Anticorps diriges contre des haptenes de quetiapine et leur utilisation |
CA2833532C (fr) | 2012-11-15 | 2021-10-26 | Ortho-Clinical Diagnostics, Inc. | Controle de qualite et de procede d'un dispositif d'analyse d'ecoulement lateral base sur le controle de debit |
CN110412265B (zh) | 2012-11-15 | 2023-04-11 | 奥索临床诊断有限公司 | 使用反应时间的校准分析 |
CA2841692C (fr) | 2013-02-12 | 2023-08-22 | Zhong Ding | Motif de depot d'une zone d'agent reactif |
FI128503B (en) * | 2013-02-27 | 2020-06-30 | Teknologian Tutkimuskeskus Vtt Oy | Sample plate and assay procedure |
EP2777499B1 (fr) | 2013-03-15 | 2015-09-16 | Ortho-Clinical Diagnostics Inc | Dispositif de collecte d'échantillon de fluide rotatif |
EP2778679B1 (fr) | 2013-03-15 | 2017-09-27 | Ortho-Clinical Diagnostics, Inc. | Dispositif de collecte d'échantillon de fluide en forme de disque rotatif |
EP3077806B1 (fr) | 2013-12-06 | 2019-09-11 | Ortho Clinical Diagnostics, Inc. | Dispositif d'analyse doté d'un orifice de nettoyage |
US9903858B2 (en) | 2014-07-23 | 2018-02-27 | Ortho-Clinical Diagnostics, Inc. | Multiplexing with single sample metering event to increase throughput |
US11033896B2 (en) | 2014-08-08 | 2021-06-15 | Ortho-Clinical Diagnostics, Inc. | Lateral-flow assay device with filtration flow control |
US10071373B2 (en) | 2014-08-08 | 2018-09-11 | Ortho-Clinical Diagnostics, Inc. | Lateral-flow assay device having flow constrictions |
KR101621050B1 (ko) * | 2014-10-23 | 2016-05-13 | 주식회사 이뮨메드 | 의료용 진단 키트의 형광리더기 |
AU2016264112A1 (en) | 2015-05-19 | 2017-11-16 | Ortho-Clinical Diagnostics, Inc. | Method of improving liquid sample flow in assay device |
US10444250B2 (en) | 2015-12-17 | 2019-10-15 | Janssen Pharmaceutica Nv | Antibodies to risperidone and use thereof |
WO2017106508A1 (fr) | 2015-12-17 | 2017-06-22 | Janssen Pharmaceutica Nv | Anticorps dirigés contre la quétiapine et utilisation associée |
CN107242860B (zh) * | 2017-07-25 | 2021-01-19 | 京东方科技集团股份有限公司 | 荧光分子层析成像系统及方法 |
EP3460456B1 (fr) * | 2017-09-20 | 2020-08-26 | IMEC vzw | Système biocapteur permettant de détecter une lumière fluorescente d'angle supercritique |
JP7106217B2 (ja) * | 2018-08-22 | 2022-07-26 | 株式会社ディスコ | ファセット領域の検出方法及び検出装置 |
CN113993455A (zh) * | 2019-03-01 | 2022-01-28 | 维迪亚控股有限公司 | 光学元件或与光学元件有关的改进 |
EP3705875B1 (fr) | 2019-03-05 | 2022-11-30 | IMEC vzw | Appareil et procédé de détection de la lumière photoluminescente émise à partir d'un échantillon |
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GB965084A (en) * | 1959-04-17 | 1964-07-29 | Lumalampan Ab | Improvements in or relating to an electroluminescent device |
US3593055A (en) * | 1969-04-16 | 1971-07-13 | Bell Telephone Labor Inc | Electro-luminescent device |
US3973129A (en) * | 1975-01-10 | 1976-08-03 | Bell Telephone Laboratories, Incorporated | Fluorimetric apparatus and method for analysis of body fluid |
WO1983001112A1 (fr) * | 1981-09-18 | 1983-03-31 | Carter, Timothy | Procede de determination d'especes en solution avec un guide d'onde optique |
US4956150A (en) * | 1985-11-27 | 1990-09-11 | Alerchek | Disposable microtiter stick |
US5158720A (en) * | 1985-12-09 | 1992-10-27 | Mcdonnell Douglas Corporation | Method and system for continuous in situ monitoring of viscosity |
CA1321488C (fr) * | 1987-08-22 | 1993-08-24 | Martin Francis Finlan | Detecteurs biologiques |
GB8827853D0 (en) * | 1988-11-29 | 1988-12-29 | Ares Serono Res & Dev Ltd | Sensor for optical assay |
US6905882B2 (en) | 1992-05-21 | 2005-06-14 | Biosite, Inc. | Diagnostic devices and apparatus for the controlled movement of reagents without membranes |
US6156270A (en) | 1992-05-21 | 2000-12-05 | Biosite Diagnostics, Inc. | Diagnostic devices and apparatus for the controlled movement of reagents without membranes |
US5885527A (en) * | 1992-05-21 | 1999-03-23 | Biosite Diagnostics, Inc. | Diagnostic devices and apparatus for the controlled movement of reagents without membrances |
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JP3326708B2 (ja) * | 1993-08-31 | 2002-09-24 | 日水製薬株式会社 | 光学的測定装置およびその方法 |
JPH07199236A (ja) * | 1993-12-28 | 1995-08-04 | Fujitsu Ltd | 光スイッチ及び光分配器 |
US5399499A (en) * | 1994-05-13 | 1995-03-21 | Eastman Kodak Company | Method of using multiwavelength upconversion for sample element interrogation in medical diagnostic equipment |
JPH07318481A (ja) * | 1994-05-25 | 1995-12-08 | Daikin Ind Ltd | 光学的測定方法およびその装置 |
JPH10501616A (ja) * | 1994-05-27 | 1998-02-10 | ノバルティス アクチエンゲゼルシャフト | 漸減励起された発光を検出するための方法 |
EP0736767A1 (fr) * | 1995-04-07 | 1996-10-09 | Ciba-Geigy Ag | Dispositif de détection optique pour des mesures analytiques de substances chimiques |
DK0918984T3 (da) * | 1996-08-16 | 2001-10-22 | Zeptosens Ag | Optisk detektionsanordning |
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DE59811600D1 (de) * | 1997-09-10 | 2004-07-29 | Artificial Sensing Instr Asi A | Optischer sensor und optisches verfahren zur charakterisierung einer chemischen und/oder biochemischen substanz |
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DE19810615A1 (de) | 1998-03-12 | 1999-09-16 | Thomas Ruckstuhl | Optische Anordnung zum Erfassen von Licht |
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WO2001057501A1 (fr) | 2000-02-03 | 2001-08-09 | Alpha Innotech Corporation | Lecteur de jeux ordonnes de microechantillons ameliore |
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EP1470401A4 (fr) * | 2002-01-12 | 2007-08-29 | Maven Technologies Llc | Dispositif et procede formation d'images |
KR20030064298A (ko) * | 2002-01-23 | 2003-07-31 | 가부시키가이샤 히다치 고쿠사이 덴키 | 형광체 검사 방법 및 형광체 검사 장치 |
US6867420B2 (en) * | 2002-06-03 | 2005-03-15 | The Regents Of The University Of California | Solid-state detector and optical system for microchip analyzers |
JP4193421B2 (ja) * | 2002-06-06 | 2008-12-10 | ソニー株式会社 | バイオアッセイ装置及びその製造方法、並びにバイオアッセイ方法 |
SE0201738D0 (sv) | 2002-06-07 | 2002-06-07 | Aamic Ab | Micro-fluid structures |
JP4480130B2 (ja) * | 2003-12-16 | 2010-06-16 | キヤノン株式会社 | 光学分析装置 |
KR100568298B1 (ko) * | 2004-03-30 | 2006-04-05 | 삼성전기주식회사 | 외부양자효율이 개선된 질화물 반도체 및 그 제조방법 |
SE529711C2 (sv) * | 2006-03-22 | 2007-11-06 | Aamic Ab | Fluorescensläsare |
-
2006
- 2006-03-22 SE SE0600642A patent/SE529711C2/sv unknown
-
2007
- 2007-03-21 JP JP2009501380A patent/JP5705432B2/ja active Active
- 2007-03-21 AU AU2007227809A patent/AU2007227809B2/en active Active
- 2007-03-21 EP EP07716079.4A patent/EP1996922B1/fr active Active
- 2007-03-21 WO PCT/SE2007/000275 patent/WO2007108752A1/fr active Application Filing
- 2007-03-21 CN CN201210123087.2A patent/CN102636469B/zh active Active
- 2007-03-21 CN CN2007800096888A patent/CN101405594B/zh active Active
- 2007-03-21 BR BRPI0709018-8A patent/BRPI0709018A2/pt not_active Application Discontinuation
- 2007-03-22 US US11/726,973 patent/US8691153B2/en active Active
-
2014
- 2014-03-31 US US14/230,926 patent/US9279768B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
JP2009530637A (ja) | 2009-08-27 |
WO2007108752A1 (fr) | 2007-09-27 |
SE529711C2 (sv) | 2007-11-06 |
AU2007227809B2 (en) | 2012-10-04 |
CN102636469A (zh) | 2012-08-15 |
US20140212984A1 (en) | 2014-07-31 |
CN101405594B (zh) | 2012-06-27 |
JP5705432B2 (ja) | 2015-04-22 |
CN101405594A (zh) | 2009-04-08 |
CN102636469B (zh) | 2016-07-06 |
EP1996922B1 (fr) | 2018-11-21 |
US20070231883A1 (en) | 2007-10-04 |
EP1996922A4 (fr) | 2012-10-24 |
AU2007227809A1 (en) | 2007-09-27 |
US9279768B2 (en) | 2016-03-08 |
US8691153B2 (en) | 2014-04-08 |
EP1996922A1 (fr) | 2008-12-03 |
SE0600642L (sv) | 2007-09-23 |
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Date | Code | Title | Description |
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B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL |