BRPI0614709B8 - Sistema e método de recheio de coluna - Google Patents

Sistema e método de recheio de coluna

Info

Publication number
BRPI0614709B8
BRPI0614709B8 BRPI0614709A BRPI0614709A BRPI0614709B8 BR PI0614709 B8 BRPI0614709 B8 BR PI0614709B8 BR PI0614709 A BRPI0614709 A BR PI0614709A BR PI0614709 A BRPI0614709 A BR PI0614709A BR PI0614709 B8 BRPI0614709 B8 BR PI0614709B8
Authority
BR
Brazil
Prior art keywords
column
bed
filling system
control unit
column filling
Prior art date
Application number
BRPI0614709A
Other languages
English (en)
Inventor
Windahl Kristian
Original Assignee
Ge Healthcare Bio Sciences Ab
Cytiva Sweden Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare Bio Sciences Ab, Cytiva Sweden Ab filed Critical Ge Healthcare Bio Sciences Ab
Publication of BRPI0614709A2 publication Critical patent/BRPI0614709A2/pt
Publication of BRPI0614709B1 publication Critical patent/BRPI0614709B1/pt
Publication of BRPI0614709B8 publication Critical patent/BRPI0614709B8/pt

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/50Conditioning of the sorbent material or stationary liquid
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/10Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/12Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the preparation of the feed
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/10Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/20Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the sorbent material
    • B01D15/206Packing or coating
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/50Conditioning of the sorbent material or stationary liquid
    • G01N30/52Physical parameters
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/50Conditioning of the sorbent material or stationary liquid
    • G01N30/56Packing methods or coating methods
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/60Construction of the column
    • G01N30/6004Construction of the column end pieces
    • G01N30/6021Adjustable pistons
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/50Conditioning of the sorbent material or stationary liquid
    • G01N30/56Packing methods or coating methods
    • G01N2030/562Packing methods or coating methods packing
    • G01N2030/565Packing methods or coating methods packing slurry packing

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)

Abstract

SISTEMA E METODO DE RECHEIO DE COLUNA. Um sistema de recheio de coluna inclui uma unidade de controle provida com um software para monitorar a pressão no interior da coluna e/ou fluxo através da coluna para uso no cálculo do ponto de interrupção onde um adaptador móvel entra em contato com um leito consolidado de meio de leito. O ponto de interrupção calculado é usado pela unidade de controle para determinar quanto mais adicionalmente o adaptador móvel tem que se mover dentro da coluna a fim de alcançar uma quantia desejada de compressão de leito.
BRPI0614709A 2005-10-21 2006-10-20 Sistema e método de recheio de coluna BRPI0614709B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/255,682 US7452471B2 (en) 2005-10-21 2005-10-21 Automated packing system and method for chromatography columns
US11/255,682 2005-10-21
PCT/EP2006/010131 WO2007045491A2 (en) 2005-10-21 2006-10-20 Automated packing system and method for chromatography columns

Publications (3)

Publication Number Publication Date
BRPI0614709A2 BRPI0614709A2 (pt) 2011-04-12
BRPI0614709B1 BRPI0614709B1 (pt) 2017-05-23
BRPI0614709B8 true BRPI0614709B8 (pt) 2022-07-05

Family

ID=37719292

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0614709A BRPI0614709B8 (pt) 2005-10-21 2006-10-20 Sistema e método de recheio de coluna

Country Status (12)

Country Link
US (2) US7452471B2 (pt)
EP (1) EP1938094B1 (pt)
JP (1) JP4898819B2 (pt)
KR (1) KR101280637B1 (pt)
CN (1) CN101238366B (pt)
AU (1) AU2006303466B2 (pt)
BR (1) BRPI0614709B8 (pt)
CA (1) CA2619818C (pt)
DK (1) DK1938094T3 (pt)
ES (1) ES2556647T3 (pt)
RU (1) RU2399046C2 (pt)
WO (1) WO2007045491A2 (pt)

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US7419599B2 (en) * 2005-07-12 2008-09-02 Ge Healthcare Bio-Sciences Ab Automated packing system and method for chromatography columns
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GB0614316D0 (en) * 2006-07-19 2006-08-30 Ge Healthcare Bio Sciences Ab Axial Chromatography Columns and Methods
JP5048785B2 (ja) * 2006-12-13 2012-10-17 バイオ−ラッド ラボラトリーズ,インコーポレイティド 分取クロマトグラフィカラムのための支持構造
CN101622044B (zh) 2007-03-06 2013-01-02 通用电气医疗集团生物科学公司 色谱柱和介质填充的自动化系统和方法
US8117901B2 (en) * 2007-07-06 2012-02-21 Ge Healthcare Bio-Sciences Ab Determination of slurry concentration
WO2009089221A1 (en) * 2008-01-07 2009-07-16 Bio-Rad Laboratories, Inc. Piston position detection for preparative chromatography column
US8454834B2 (en) * 2008-01-23 2013-06-04 Ge Healthcare Bio-Sciences Ab Column packing method
JP5675593B2 (ja) * 2008-05-30 2015-02-25 ジーイー・ヘルスケア・バイオサイエンス・アクチボラグ 自動式カラムパッキング方法
US8066882B2 (en) * 2008-05-30 2011-11-29 Ge Healthcare Bio-Sciences Ab Column packing method
WO2009157853A1 (en) * 2008-06-27 2009-12-30 Ge Healthcare Bio-Sciences Ab Separation media slurry tank
US8066876B2 (en) 2009-11-23 2011-11-29 Agilent Technologies, Inc. Apparatus and methods for packing chromatography columns
CN102656452B (zh) * 2009-12-22 2015-07-22 通用电气健康护理生物科学股份公司 用于干填充色谱柱的方法
US20110259831A1 (en) * 2010-04-22 2011-10-27 Michael Brandt Tracking regulator system and method for processing columns
GB2485838A (en) * 2010-11-29 2012-05-30 Ge Healthcare Bio Sciences Ab Chromatography column
CN102120102B (zh) * 2010-11-30 2013-02-27 顾雄毅 用于生化分离技术的膨胀床色谱分离装置
JP5630299B2 (ja) * 2011-02-02 2014-11-26 栗田工業株式会社 液体クロマトグラフィー装置及び充填剤の充填方法
JP5922373B2 (ja) * 2011-10-31 2016-05-24 日機装株式会社 血液吸着器の製造方法及び製造装置
JP6461930B2 (ja) * 2013-09-30 2019-01-30 ジーイー・ヘルスケア・バイオサイエンス・アクチボラグ スラリーの移送法
CN104307206B (zh) * 2014-02-17 2017-04-05 源创精科生物科技(长沙)有限公司 一种用于层析柱的静密封多通道喷头设计
US20170248559A1 (en) * 2014-06-02 2017-08-31 Flom Corporation Column packing apparatus and packing method
GB201701576D0 (en) * 2017-01-31 2017-03-15 Ge Healthcare Bio Sciences Ab Method and system for transferring separation resin
GB201715403D0 (en) 2017-09-22 2017-11-08 Ge Healthcare Bio Sciences Ab Chromatography apparatus
GB201710279D0 (en) 2017-06-28 2017-08-09 Ge Healthcare Bio Sciences Ab Improvements in and relating to bioprocessing equipment and fluid couplings therefor
CN107126726A (zh) * 2017-06-30 2017-09-05 江苏汉邦科技有限公司 一种喷胶装置
CN107457125B (zh) * 2017-09-29 2024-04-02 江苏汉邦科技股份有限公司 一种入液阀
IL302722B1 (en) * 2017-10-17 2024-03-01 Regeneron Pharma Methods for determining mixture for resin chromatography
US11745119B2 (en) 2018-04-16 2023-09-05 Asahi Kasei Bioprocess America, Inc. Chromatography and synthesis column apparatus and method of assembly
CN109011697A (zh) * 2018-09-25 2018-12-18 常州瑞曦生物科技有限公司 低压层析柱
US11731062B2 (en) 2021-01-20 2023-08-22 Asahi Kasei Bioprocess America, Inc. Components that facilitate maintenance of chromatography and synthesis columns
WO2022196275A1 (ja) * 2021-03-17 2022-09-22 日本水産株式会社 精製の方法および精製された製品
CN113069791B (zh) * 2021-03-31 2022-07-12 温州市质量技术检测科学研究院 一种硅藻土自动定量填充萃取装置及方法
CN113915177B (zh) * 2021-09-16 2024-05-14 利穗科技(苏州)有限公司 一种电液伺服驱动装置及层析设备
NL2030851B1 (en) * 2022-02-08 2023-09-05 Jemp Holding Bv Method of packing a chromatography column system.

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CN1386196A (zh) * 2000-07-28 2002-12-18 欧洲流程(英国)有限公司 用于填充色谱柱的方法和设备以及色谱柱
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US7435350B2 (en) * 2005-04-04 2008-10-14 Millipore Corporation Intelligent system and method for automated packing of chromatography columns
US7452471B2 (en) * 2005-10-21 2008-11-18 Ge Healthcare Bio-Sciences Ab Automated packing system and method for chromatography columns
US7419599B2 (en) * 2005-07-12 2008-09-02 Ge Healthcare Bio-Sciences Ab Automated packing system and method for chromatography columns
CN101248352B (zh) * 2005-05-20 2012-09-05 通用电气健康护理生物科学股份公司 用于色谱柱自动填料的装置和方法

Also Published As

Publication number Publication date
WO2007045491A2 (en) 2007-04-26
EP1938094B1 (en) 2015-09-30
WO2007045491A3 (en) 2007-07-19
EP1938094A2 (en) 2008-07-02
CN101238366B (zh) 2012-09-05
CN101238366A (zh) 2008-08-06
JP4898819B2 (ja) 2012-03-21
US20070090053A1 (en) 2007-04-26
RU2399046C2 (ru) 2010-09-10
JP2009512840A (ja) 2009-03-26
AU2006303466B2 (en) 2012-03-22
US7452471B2 (en) 2008-11-18
AU2006303466A1 (en) 2007-04-26
BRPI0614709B1 (pt) 2017-05-23
CA2619818C (en) 2012-05-29
ES2556647T3 (es) 2016-01-19
US9110060B2 (en) 2015-08-18
KR101280637B1 (ko) 2013-07-01
KR20080057215A (ko) 2008-06-24
BRPI0614709A2 (pt) 2011-04-12
DK1938094T3 (en) 2016-01-04
US20090038381A1 (en) 2009-02-12
RU2008104936A (ru) 2009-09-10
CA2619818A1 (en) 2007-04-26

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]
B25D Requested change of name of applicant approved