BRPI0610968A2 - composição de sangue de cordão umbilical, e, métodos para tratar uma doença maligna ou distúrbio benigno associado com o sistema hemoatopoiético e para preparar uma composição de sangue umbilical - Google Patents
composição de sangue de cordão umbilical, e, métodos para tratar uma doença maligna ou distúrbio benigno associado com o sistema hemoatopoiético e para preparar uma composição de sangue umbilicalInfo
- Publication number
- BRPI0610968A2 BRPI0610968A2 BRPI0610968-3A BRPI0610968A BRPI0610968A2 BR PI0610968 A2 BRPI0610968 A2 BR PI0610968A2 BR PI0610968 A BRPI0610968 A BR PI0610968A BR PI0610968 A2 BRPI0610968 A2 BR PI0610968A2
- Authority
- BR
- Brazil
- Prior art keywords
- blood composition
- ucb
- hemoatopoietic
- treating
- methods
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 4
- 201000010099 disease Diseases 0.000 title abstract 3
- 210000004700 fetal blood Anatomy 0.000 title abstract 3
- 230000003211 malignant effect Effects 0.000 title abstract 3
- 208000035475 disorder Diseases 0.000 title abstract 2
- 210000004369 blood Anatomy 0.000 title 1
- 239000008280 blood Substances 0.000 title 1
- 210000004027 cell Anatomy 0.000 abstract 2
- 210000003743 erythrocyte Anatomy 0.000 abstract 2
- 238000010257 thawing Methods 0.000 abstract 2
- 238000005138 cryopreservation Methods 0.000 abstract 1
- 210000003958 hematopoietic stem cell Anatomy 0.000 abstract 1
- 238000001802 infusion Methods 0.000 abstract 1
- 238000011084 recovery Methods 0.000 abstract 1
- 238000002054 transplantation Methods 0.000 abstract 1
- 210000003954 umbilical cord Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/51—Umbilical cord; Umbilical cord blood; Umbilical stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Developmental Biology & Embryology (AREA)
- General Chemical & Material Sciences (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Transplantation (AREA)
- Dentistry (AREA)
- Communicable Diseases (AREA)
- Environmental Sciences (AREA)
- Reproductive Health (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Diabetes (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
composição de sangue de cordão umbilical, e, métodos para tratar uma doença maligna ou distúrbio benigno associado com o sistema hemoatopoiético e para preparar uma composição de sangue de cordão umbilical as composições de sangue de cordão umbilical (ucb) da presente invenção compreendem as características únicas de apresentarem plasma que é substancialmente depletado da unidade de ucb e células sanguíneas vermelhas (rbc) que não são depletadas da unidade de ucb. referidas unidades de ucb podem ser preparadas por meio de um processo que combina depleção de plasma com crioconservação, seleção, descongelamento, e/ou transplante de células-tronco hematopoiéticas proporcionando resultado clínico superior mediante a maximização da recuperação de células após o processamento e dose de células de infusão após o descongelamento. proporciona-se também métodos para tratamento de uma ampla variedade de doenças malignas e de doenças benignas associadas com o sistema hemoatopoiético mediante administração de composições de ucb da presente invenção.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US68712705P | 2005-06-02 | 2005-06-02 | |
US60/687127 | 2005-06-02 | ||
US73395605P | 2005-11-03 | 2005-11-03 | |
US60/733956 | 2005-11-03 | ||
PCT/US2006/021405 WO2006130812A2 (en) | 2005-06-02 | 2006-06-02 | Plasma-depleted, non-red blood cell-depleted cord blood compositions and methods of use |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0610968A2 true BRPI0610968A2 (pt) | 2019-05-14 |
Family
ID=37482333
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0610968-3A BRPI0610968A2 (pt) | 2005-06-02 | 2006-06-02 | composição de sangue de cordão umbilical, e, métodos para tratar uma doença maligna ou distúrbio benigno associado com o sistema hemoatopoiético e para preparar uma composição de sangue umbilical |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP1906729B1 (pt) |
JP (1) | JP2008545755A (pt) |
KR (1) | KR20080027295A (pt) |
AT (1) | ATE551062T1 (pt) |
AU (1) | AU2006252363A1 (pt) |
BR (1) | BRPI0610968A2 (pt) |
CA (1) | CA2609266A1 (pt) |
HK (1) | HK1124484A1 (pt) |
IL (1) | IL187641A0 (pt) |
MX (1) | MX2007015201A (pt) |
RU (1) | RU2007148802A (pt) |
WO (1) | WO2006130812A2 (pt) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008121120A1 (en) * | 2007-03-28 | 2008-10-09 | Thermogenesis Corp. | Stem and progenitor cell compositions recovered from bone marrow or cord blood; system and method for preparation thereof |
CN102144028B (zh) * | 2008-09-03 | 2017-12-26 | 中胚有限公司 | 造血前体的扩增 |
CA2795627C (en) * | 2010-04-09 | 2023-03-14 | Fred Hutchinson Cancer Research Center | Compositions and methods for providing hematopoietic function without hla matching |
WO2011127472A1 (en) * | 2010-04-09 | 2011-10-13 | Fred Hutchinson Cancer Research Center | Compositions and methods for providing hematopoietic function |
CN107306937A (zh) * | 2011-02-18 | 2017-11-03 | 永生细胞公司 | 干细胞的包装和运输 |
US9943545B2 (en) | 2013-03-15 | 2018-04-17 | Fate Therapeutics, Inc. | Stem cell culture media and methods of enhancing cell survival |
JP6531256B2 (ja) * | 2014-11-14 | 2019-06-19 | 日本赤十字社 | 臍帯血および末梢血の凍結保存方法および凍結保存用溶液 |
RU2590688C2 (ru) * | 2014-11-19 | 2016-07-10 | Публичное акционерное общество "Институт Стволовых Клеток Человека" | Способ получения суспензии ядросодержащих клеток из пуповинной крови со стандартизированной концентрацией |
JP6474499B2 (ja) * | 2015-03-06 | 2019-02-27 | アジュ ユニバーシティー インダストリー−アカデミック コーオペレイション ファウンデーションAjou University Industry−Academic Cooperation Foundation | 癌治療用細胞治療剤およびその併用療法 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5789147A (en) * | 1994-12-05 | 1998-08-04 | New York Blood Center, Inc. | Method for concentrating white cells from whole blood by adding a red cell sedimentation reagent to whole anticoagulated blood |
US20030215942A1 (en) * | 2002-02-14 | 2003-11-20 | Stemcyte, Inc. | Undesignated allogeneic stem cell bank |
-
2006
- 2006-06-02 CA CA002609266A patent/CA2609266A1/en not_active Abandoned
- 2006-06-02 RU RU2007148802/15A patent/RU2007148802A/ru not_active Application Discontinuation
- 2006-06-02 EP EP06771915A patent/EP1906729B1/en not_active Not-in-force
- 2006-06-02 AT AT06771915T patent/ATE551062T1/de active
- 2006-06-02 JP JP2008514888A patent/JP2008545755A/ja active Pending
- 2006-06-02 WO PCT/US2006/021405 patent/WO2006130812A2/en active Application Filing
- 2006-06-02 AU AU2006252363A patent/AU2006252363A1/en not_active Abandoned
- 2006-06-02 BR BRPI0610968-3A patent/BRPI0610968A2/pt not_active Application Discontinuation
- 2006-06-02 MX MX2007015201A patent/MX2007015201A/es not_active Application Discontinuation
- 2006-06-02 KR KR1020077031030A patent/KR20080027295A/ko not_active Application Discontinuation
-
2007
- 2007-11-26 IL IL187641A patent/IL187641A0/en unknown
-
2009
- 2009-02-26 HK HK09101826.9A patent/HK1124484A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
KR20080027295A (ko) | 2008-03-26 |
EP1906729B1 (en) | 2012-03-28 |
JP2008545755A (ja) | 2008-12-18 |
RU2007148802A (ru) | 2009-07-20 |
WO2006130812A3 (en) | 2007-09-13 |
HK1124484A1 (en) | 2009-07-17 |
EP1906729A4 (en) | 2009-08-12 |
AU2006252363A1 (en) | 2006-12-07 |
IL187641A0 (en) | 2008-03-20 |
CA2609266A1 (en) | 2006-12-07 |
WO2006130812A2 (en) | 2006-12-07 |
EP1906729A2 (en) | 2008-04-09 |
MX2007015201A (es) | 2008-03-14 |
ATE551062T1 (de) | 2012-04-15 |
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Legal Events
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B06G | Technical and formal requirements: other requirements [chapter 6.7 patent gazette] |
Free format text: SOLICITA-SE A REGULARIZACAO DA PROCURACAO, UMA VEZ QUE BASEADO NO ARTIGO 216 1O DA LPI, O DOCUMENTO DE PROCURACAO DEVE SER APRESENTADO NO ORIGINAL, TRASLADO OU FOTOCOPIA AUTENTICADA. |
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B11Z | Dismissal: petition dismissal - article 216, par 2 of industrial property law |
Free format text: REFERENTE A PETICAO 020070170526/RJ DE 30/11/2007. |
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B06H | Technical and formal requirements: requirement cancelled [chapter 6.8 patent gazette] |
Free format text: ANULADA A PUBLICACAO CODIGO 6.7 NA RPI NO 2080 DE 16/11/2010 POR TER SIDO INDEVIDA. |
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B11M | Decision cancelled [chapter 11.13 patent gazette] |
Free format text: ANULADA A PUBLICACAO CODIGO 11.6.1 NA RPI NO 2135 DE 06/12/2011 POR TER SIDO INDEVIDA. |
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B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] | ||
B350 | Update of information on the portal [chapter 15.35 patent gazette] |