BRPI0609736A2 - composto e sais farmaceuticamente acetáveis do mesmo, formulação farmacêutica, métodos para tratar, ou reduzir o risco de, uma doença ou condição humanas, de distúrbios ou doenças, e de esclerose múltipla e para tratamento ou profilaxia da aterosclerose, uso de um composto ou um sal farmaceuticamente aceitável do mesmo, processo para a preparação de um composto ou de um sal farmaceuticamente acetável do mesmo - Google Patents
composto e sais farmaceuticamente acetáveis do mesmo, formulação farmacêutica, métodos para tratar, ou reduzir o risco de, uma doença ou condição humanas, de distúrbios ou doenças, e de esclerose múltipla e para tratamento ou profilaxia da aterosclerose, uso de um composto ou um sal farmaceuticamente aceitável do mesmo, processo para a preparação de um composto ou de um sal farmaceuticamente acetável do mesmo Download PDFInfo
- Publication number
- BRPI0609736A2 BRPI0609736A2 BRPI0609736-7A BRPI0609736A BRPI0609736A2 BR PI0609736 A2 BRPI0609736 A2 BR PI0609736A2 BR PI0609736 A BRPI0609736 A BR PI0609736A BR PI0609736 A2 BRPI0609736 A2 BR PI0609736A2
- Authority
- BR
- Brazil
- Prior art keywords
- amino
- pyrimidin
- thiazolo
- compound
- formula
- Prior art date
Links
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Cardiology (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0500768 | 2005-04-06 | ||
| SE0500768-7 | 2005-04-06 | ||
| PCT/SE2006/000398 WO2006107257A1 (en) | 2005-04-06 | 2006-04-03 | Novel 5,7-disubstituted [1,3]thiazolo[4,5-d]pyrimidin-2(3h)-one derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0609736A2 true BRPI0609736A2 (pt) | 2011-10-18 |
Family
ID=37073738
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0609736-7A BRPI0609736A2 (pt) | 2005-04-06 | 2006-04-03 | composto e sais farmaceuticamente acetáveis do mesmo, formulação farmacêutica, métodos para tratar, ou reduzir o risco de, uma doença ou condição humanas, de distúrbios ou doenças, e de esclerose múltipla e para tratamento ou profilaxia da aterosclerose, uso de um composto ou um sal farmaceuticamente aceitável do mesmo, processo para a preparação de um composto ou de um sal farmaceuticamente acetável do mesmo |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US8088780B2 (enExample) |
| EP (1) | EP1869055A1 (enExample) |
| JP (1) | JP2008535834A (enExample) |
| KR (1) | KR20080004484A (enExample) |
| CN (1) | CN101193898B (enExample) |
| AR (1) | AR053347A1 (enExample) |
| AU (1) | AU2006231835B8 (enExample) |
| BR (1) | BRPI0609736A2 (enExample) |
| CA (1) | CA2604016A1 (enExample) |
| IL (1) | IL185913A0 (enExample) |
| MX (1) | MX2007012067A (enExample) |
| NO (1) | NO20075610L (enExample) |
| NZ (1) | NZ561462A (enExample) |
| RU (1) | RU2411245C9 (enExample) |
| TW (1) | TW200720279A (enExample) |
| UY (1) | UY29451A1 (enExample) |
| WO (1) | WO2006107257A1 (enExample) |
| ZA (1) | ZA200708182B (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2641815T3 (es) | 2004-10-29 | 2017-11-14 | Eisai R&D Management Co., Ltd. | Tratamiento para enfermedades inflamatorias |
| UA90707C2 (en) * | 2005-04-06 | 2010-05-25 | Астразенека Аб | Novel 5-substituted 7-amino-[1,3]thiazolo[4,5-d]pyrimidine derivatives |
| TW200820973A (en) | 2006-09-29 | 2008-05-16 | Astrazeneca Ab | Novel compounds 480 |
| PL2254870T3 (pl) | 2008-03-07 | 2016-07-29 | Acraf | Pochodne 1-benzylo-3-hydroksymetyloindazolu i ich zastosowanie w leczeniu chorób opartych na ekspresji MCP-1, CX3CR1 |
| GEP20135913B (en) | 2008-03-07 | 2013-08-26 | Acraf | 1-benzyl-3-hydroxymethylindazole derivatives and use thereat treatment of diseases based on mcp-1 and cx3cr1 expression |
| MX2010009625A (es) | 2008-03-07 | 2010-09-28 | Acraf | Derivados de 1-bencil-3-hidroximetilindazol y uso de los mismos en el tratamiento de enfermedades basadas en la expresion de mcp-1, cx3cr1 y p40. |
| AR071036A1 (es) * | 2008-03-26 | 2010-05-19 | Astrazeneca Ab | Derivados 5, 7-disustituidos de [1, 3]tiazolo[4, 5-d]pirimidin-2 (3h)-ona, una composicion farmaceutica que los comprende y su uso en el tratamiento de enfermedades mediadas por el receptor cx3cr1. |
| AR076601A1 (es) | 2009-05-21 | 2011-06-22 | Chlorion Pharma Inc | Pirimidinas como agentes terapeuticos |
| JO3437B1 (ar) | 2009-10-30 | 2019-10-20 | Esai R & D Man Co Ltd | أجسام مضادة محسنة مضادة للفراكتالكين البشري واستخداماتها |
| US8476301B2 (en) | 2011-09-13 | 2013-07-02 | Eisai R&D Management Co., Ltd. | Pyrrolidin-3-ylacetic acid derivative |
| TWI543975B (zh) * | 2011-09-13 | 2016-08-01 | Eisai R&D Man Co Ltd | Pyrrolidin-3-yl acetic acid derivatives |
| KR20150129698A (ko) * | 2013-03-12 | 2015-11-20 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 피롤리딘-3-일 아세트산 유도체의 염 및 그의 결정 |
| WO2014142086A1 (ja) * | 2013-03-13 | 2014-09-18 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | ピロリジン－３－イル酢酸誘導体およびピペリジン－３－イル酢酸誘導体 |
| JP6779232B2 (ja) * | 2015-05-08 | 2020-11-04 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | ウイルス感染の治療又は予防のための新規オキサチオランカルボン酸と誘導体 |
| GB201811169D0 (en) * | 2018-07-06 | 2018-08-29 | Kancera Ab | New compounds |
| CN120077035A (zh) | 2022-10-19 | 2025-05-30 | 阿斯利康(瑞典)有限公司 | 作为cx3cr1的调节剂的2,4,6-三取代的1,3,5-三嗪 |
| WO2025219939A1 (en) | 2024-04-17 | 2025-10-23 | Astrazeneca Ab | Salts and polymorphs of cx3cr1 modulators |
| WO2025219950A1 (en) | 2024-04-18 | 2025-10-23 | Astrazeneca Ab | Small molecule cx3cr1 modulators |
| WO2025219947A1 (en) | 2024-04-18 | 2025-10-23 | Astrazeneca Ab | Thio-substituted 1,3,5-triazine cx3cr1 modulators |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE543978A (enExample) | 1955-01-03 | |||
| US4698327A (en) | 1985-04-25 | 1987-10-06 | Eli Lilly And Company | Novel glycopeptide derivatives |
| US4639433A (en) | 1985-08-14 | 1987-01-27 | Eli Lilly And Company | Glycopeptide derivatives |
| US4643987A (en) | 1985-08-14 | 1987-02-17 | Eli Lilly And Company | Modified glycopeptides |
| CA2031803C (en) | 1989-12-13 | 2001-05-29 | Ramakrishnan Nagarajan | Improvements in or relating to glycopeptide deriveratives |
| US5202328A (en) | 1991-03-06 | 1993-04-13 | Merck & Co., Inc. | Substituted fused pyrimidinones |
| US5840684A (en) | 1994-01-28 | 1998-11-24 | Eli Lilly And Company | Glycopeptide antibiotic derivatives |
| ATE214704T1 (de) * | 1997-07-18 | 2002-04-15 | Hoffmann La Roche | 5h-thiazolo(3,2-a)pyrimidinderivate |
| WO1999051608A1 (en) | 1998-04-03 | 1999-10-14 | Du Pont Pharmaceuticals Company | THIAZOLO[4,5-d]PYRIMIDINES AND PYRIDINES AS CORTICOTROPIN RELEASING FACTOR (CRF) ANTAGONISTS |
| AU2881399A (en) | 1998-05-01 | 1999-11-23 | Eli Lilly And Company | N1-modified glycopeptides |
| SE9802729D0 (sv) | 1998-08-13 | 1998-08-13 | Astra Pharma Prod | Novel Compounds |
| SE9903544D0 (sv) | 1999-10-01 | 1999-10-01 | Astra Pharma Prod | Novel compounds |
| GB2359081A (en) | 2000-02-11 | 2001-08-15 | Astrazeneca Uk Ltd | Pharmaceutically active thiazolopyrimidines |
| DE60101372T2 (de) * | 2000-02-11 | 2004-10-14 | Astrazeneca Ab | Pyrimidinverbindungen und ihre verwendung als modulatoren der chemokin-rezeptor-aktivität |
| GB2359551A (en) | 2000-02-23 | 2001-08-29 | Astrazeneca Uk Ltd | Pharmaceutically active pyrimidine derivatives |
| SE0004110L (sv) | 2000-11-10 | 2002-05-11 | Forsheda Ab | Tätningsring |
| SE0101082D0 (sv) | 2001-03-27 | 2001-03-27 | Astrazeneca Ab | Novel use |
| SE0101322D0 (sv) | 2001-04-12 | 2001-04-12 | Astrazeneca Ab | Novel compounds |
| GB0221829D0 (en) * | 2002-09-20 | 2002-10-30 | Astrazeneca Ab | Novel compound |
| GB0221828D0 (en) | 2002-09-20 | 2002-10-30 | Astrazeneca Ab | Novel compound |
| EP1675862A1 (en) * | 2003-10-07 | 2006-07-05 | AstraZeneca AB | New 2-substituted, 4-amino-thiazolo 4,5-d pyrimidines, useful as chemokine receptor antagonists, esp. cx3cr1 |
| UA90707C2 (en) | 2005-04-06 | 2010-05-25 | Астразенека Аб | Novel 5-substituted 7-amino-[1,3]thiazolo[4,5-d]pyrimidine derivatives |
-
2006
- 2006-03-27 AR ARP060101170A patent/AR053347A1/es not_active Application Discontinuation
- 2006-03-28 TW TW095110787A patent/TW200720279A/zh unknown
- 2006-04-03 RU RU2007140552/04A patent/RU2411245C9/ru not_active IP Right Cessation
- 2006-04-03 WO PCT/SE2006/000398 patent/WO2006107257A1/en not_active Ceased
- 2006-04-03 EP EP06717077A patent/EP1869055A1/en not_active Withdrawn
- 2006-04-03 NZ NZ561462A patent/NZ561462A/en not_active IP Right Cessation
- 2006-04-03 BR BRPI0609736-7A patent/BRPI0609736A2/pt not_active Application Discontinuation
- 2006-04-03 MX MX2007012067A patent/MX2007012067A/es not_active Application Discontinuation
- 2006-04-03 JP JP2008505261A patent/JP2008535834A/ja active Pending
- 2006-04-03 CN CN2006800200730A patent/CN101193898B/zh not_active Expired - Fee Related
- 2006-04-03 AU AU2006231835A patent/AU2006231835B8/en not_active Ceased
- 2006-04-03 KR KR1020077022814A patent/KR20080004484A/ko not_active Withdrawn
- 2006-04-03 US US11/910,781 patent/US8088780B2/en not_active Expired - Fee Related
- 2006-04-03 CA CA002604016A patent/CA2604016A1/en not_active Abandoned
- 2006-04-04 UY UY29451A patent/UY29451A1/es unknown
-
2007
- 2007-09-11 IL IL185913A patent/IL185913A0/en unknown
- 2007-09-25 ZA ZA200708182A patent/ZA200708182B/xx unknown
- 2007-11-05 NO NO20075610A patent/NO20075610L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| RU2411245C2 (ru) | 2011-02-10 |
| CN101193898B (zh) | 2010-12-01 |
| ZA200708182B (en) | 2008-11-26 |
| CN101193898A (zh) | 2008-06-04 |
| WO2006107257A1 (en) | 2006-10-12 |
| NO20075610L (no) | 2008-01-07 |
| RU2007140552A (ru) | 2009-05-20 |
| TW200720279A (en) | 2007-06-01 |
| AU2006231835B2 (en) | 2010-09-30 |
| EP1869055A1 (en) | 2007-12-26 |
| MX2007012067A (es) | 2007-12-04 |
| CA2604016A1 (en) | 2006-10-12 |
| US8088780B2 (en) | 2012-01-03 |
| AU2006231835A1 (en) | 2006-10-12 |
| IL185913A0 (en) | 2008-01-06 |
| KR20080004484A (ko) | 2008-01-09 |
| US20090124637A1 (en) | 2009-05-14 |
| UY29451A1 (es) | 2006-11-30 |
| AR053347A1 (es) | 2007-05-02 |
| JP2008535834A (ja) | 2008-09-04 |
| AU2006231835B8 (en) | 2010-10-14 |
| RU2411245C9 (ru) | 2011-05-27 |
| NZ561462A (en) | 2010-12-24 |
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Legal Events
| Date | Code | Title | Description |
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| B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
| B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |