BRPI0606411A2 - uso de corantes de cianina para o diagnóstico de doenças proliferativas - Google Patents

uso de corantes de cianina para o diagnóstico de doenças proliferativas

Info

Publication number
BRPI0606411A2
BRPI0606411A2 BRPI0606411-6A BRPI0606411A BRPI0606411A2 BR PI0606411 A2 BRPI0606411 A2 BR PI0606411A2 BR PI0606411 A BRPI0606411 A BR PI0606411A BR PI0606411 A2 BRPI0606411 A2 BR PI0606411A2
Authority
BR
Brazil
Prior art keywords
diagnosis
proliferative diseases
cyanine dyes
cyanine
dyes
Prior art date
Application number
BRPI0606411-6A
Other languages
English (en)
Inventor
Kai Licha
Martin Pessel
Malte Bahner
Michael Schirner
Original Assignee
Bayer Schering Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34933224&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0606411(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Schering Pharma Ag filed Critical Bayer Schering Pharma Ag
Publication of BRPI0606411A2 publication Critical patent/BRPI0606411A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0032—Methine dyes, e.g. cyanine dyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0032—Methine dyes, e.g. cyanine dyes
    • A61K49/0034—Indocyanine green, i.e. ICG, cardiogreen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/005—Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
    • A61K49/0058—Antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

USO DE CORANTES DE CIANINA PARA O DIAGNóSTICO DE DOENçAS PROLIFERATIVAS. A presente invenção refere-se ao uso do corante de cíanina SF64 para o diagnóstico de doenças proliferativas após administração de menos do que 5 mg/kg de peso corporal.
BRPI0606411-6A 2005-01-07 2006-01-05 uso de corantes de cianina para o diagnóstico de doenças proliferativas BRPI0606411A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05000276A EP1679082A1 (en) 2005-01-07 2005-01-07 Use of cyanine dyes for the diagnosis of proliferative diseases
PCT/EP2006/000058 WO2006072580A1 (en) 2005-01-07 2006-01-05 Use of cyanine dyes for the diagnosis of proliferative diseases

Publications (1)

Publication Number Publication Date
BRPI0606411A2 true BRPI0606411A2 (pt) 2009-06-23

Family

ID=34933224

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0606411-6A BRPI0606411A2 (pt) 2005-01-07 2006-01-05 uso de corantes de cianina para o diagnóstico de doenças proliferativas

Country Status (23)

Country Link
EP (2) EP1679082A1 (pt)
JP (1) JP5578765B2 (pt)
KR (1) KR20070092270A (pt)
CN (1) CN101128218A (pt)
AR (1) AR052190A1 (pt)
AU (1) AU2006204496A1 (pt)
BR (1) BRPI0606411A2 (pt)
CA (1) CA2594390C (pt)
CR (1) CR9232A (pt)
DO (1) DOP2006000005A (pt)
GT (1) GT200600001A (pt)
IL (1) IL182499A0 (pt)
MX (1) MX2007008300A (pt)
NO (1) NO20074036L (pt)
NZ (1) NZ554917A (pt)
PA (1) PA8659101A1 (pt)
PE (2) PE20100449A1 (pt)
RU (1) RU2007129919A (pt)
TW (1) TW200635612A (pt)
UA (1) UA89976C2 (pt)
UY (1) UY29323A1 (pt)
WO (1) WO2006072580A1 (pt)
ZA (1) ZA200706533B (pt)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1619501B1 (en) * 2004-07-22 2007-09-26 Bayer Schering Pharma Aktiengesellschaft Use of cyanine dyes for the diagnosis of disease associated with angiogenesis
EP1679082A1 (en) * 2005-01-07 2006-07-12 Schering AG Use of cyanine dyes for the diagnosis of proliferative diseases
EP1743658A1 (en) * 2005-07-14 2007-01-17 Schering Aktiengesellschaft Optical imaging of rheumatoid arthritis
CA2681790A1 (en) * 2007-03-30 2008-10-09 F. Hoffmann-La Roche Ag Composition of labeled and non-labeled monoclonal antibodies
US20110262354A1 (en) 2007-07-13 2011-10-27 Emory University Cyanine-containing compounds for cancer imaging and treatment
GB0803477D0 (en) 2008-02-26 2008-04-02 Ge Healthcare As Therapy selection method
EP2303337A4 (en) * 2008-06-13 2014-09-03 Cedars Sinai Medical Center MEDICAMENT-LIGAND SMALL MOLECULE CONJUGATES FOR TARGETED CANCER TREATMENT
GB0814960D0 (en) * 2008-08-15 2008-09-24 Ge Healthcare As Method for detecting dysplasia
JP2012532846A (ja) 2009-07-09 2012-12-20 エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト インビボ腫瘍脈管構造画像処理
JP5426026B2 (ja) 2009-07-28 2014-02-26 エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト 非侵襲性インビボ光学イメージング方法
DK2470887T3 (da) 2009-08-28 2020-04-06 Visen Medical Inc Systemer til tomografisk billeddannelse i diffuse medier ved at anvende en hybrid inversionsteknik
JP2011046662A (ja) 2009-08-28 2011-03-10 Fujifilm Corp 近赤外蛍光造影剤
JP2011046663A (ja) 2009-08-28 2011-03-10 Fujifilm Corp 近赤外蛍光造影剤
JP5945226B2 (ja) 2009-09-22 2016-07-05 ビセン メディカル， インコーポレイテッド 拡散媒質の仮想屈折率整合のためのシステムおよび方法
CN102939538A (zh) 2010-05-07 2013-02-20 霍夫曼-拉罗奇有限公司 用于离体检测细胞的诊断方法
EP2683290B1 (en) 2011-03-07 2018-11-07 F.Hoffmann-La Roche Ag Methods for in vivo testing of therapeutic antibodies
JP6385060B2 (ja) 2011-03-07 2018-09-05 エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト 治療的に活性な抗体のインビボにおける選択
KR101373108B1 (ko) 2012-01-20 2014-03-27 이화여자대학교 산학협력단 폴리메틴 체인에 메조-반응작용기를 갖는 신규한 시아닌 유도체 및 이의 제조방법
CN102608051B (zh) * 2012-02-21 2015-04-08 中国科学院化学研究所 用于诊断白血病的试剂盒
CN102703569B (zh) * 2012-05-24 2014-04-09 中国科学院化学研究所 菁染料的新用途
CN102706787B (zh) * 2012-05-24 2015-04-08 中国科学院化学研究所 菁染料的新用途
US10743768B2 (en) 2012-10-15 2020-08-18 Visen Medical, Inc. Systems, methods, and apparatus for imaging of diffuse media featuring cross-modality weighting of fluorescent and bioluminescent sources
JP6384821B2 (ja) * 2012-10-26 2018-09-05 国立大学法人三重大学 がん細胞阻害薬、がん幹細胞検出用プローブ
WO2014092958A1 (en) * 2012-12-10 2014-06-19 Molecular Targeting Technologies, Inc. Compositions and methods of diagnosing ocular diseases
RU2016127260A (ru) 2013-12-31 2018-02-06 Мемориал Слоун Кеттеринг Кэнсэ Сентр Системы, способы и устройство для многоканального отображения флюоресцентных источников в режиме реального времени
RU2565645C1 (ru) * 2014-09-05 2015-10-20 Федеральное государственное бюджетное учреждение "Ростовский научно-исследовательский онкологический институт" Министерства здравоохранения Российской Федерации Способ рентгендиагностики глубины инвазии рецидива рака вульвы в мягкие ткани
JP6751715B2 (ja) 2014-12-15 2020-09-09 メモリアル スローン ケタリング キャンサー センター 神経結合選択性が増強された環状ペプチド、当該環状ペプチドと結合したナノ粒子、およびリアルタイムｉｎ ｖｉｖｏ神経組織撮像ための当該環状ペプチドの使用
BR112018011868A2 (pt) 2015-12-15 2018-12-04 Univ Cornell sistemas de imagem e métodos para diferenciação de tecidos, por exemplo, para visualização intraoperatória
AU2017368005A1 (en) 2016-11-30 2019-06-20 Cornell University Inhibitor-functionalized ultrasmall nanoparticles and methods thereof
CN111970960A (zh) 2018-03-30 2020-11-20 珀金埃尔默健康科学有限公司 使用短波红外(swir)投影层析成像对解剖器官和内含物进行3d重建的系统和方法
EP4015004A1 (en) 2020-12-18 2022-06-22 Phi Pharma SA Proteoglycan specific branched peptides

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000095758A (ja) * 1998-09-18 2000-04-04 Schering Ag 近赤外蛍光造影剤および蛍光造影方法
DE19917713A1 (de) * 1999-04-09 2000-10-19 Diagnostikforschung Inst Kurzkettige Peptid-Farbstoffkonjugate als Konstrastmittel für die optische Diagnostik
DE19947559A1 (de) * 1999-09-24 2001-04-19 Schering Ag Antikörper-Farbstoffkonjugate gegen Zielstrukturen der Angiogenese zur intraoperativen Tumorranddarstellung
WO2004065491A1 (en) * 2003-01-24 2004-08-05 Schering Ag Hydrophilic, thiol-reactive cyanine dyes and conjugates thereof with biomolecules for fluorescence diagnosis
EP1619501B1 (en) * 2004-07-22 2007-09-26 Bayer Schering Pharma Aktiengesellschaft Use of cyanine dyes for the diagnosis of disease associated with angiogenesis
EP1679082A1 (en) * 2005-01-07 2006-07-12 Schering AG Use of cyanine dyes for the diagnosis of proliferative diseases

Also Published As

Publication number Publication date
RU2007129919A (ru) 2009-02-20
JP2008526802A (ja) 2008-07-24
CR9232A (es) 2007-11-23
EP1833513B1 (en) 2013-03-06
PE20060872A1 (es) 2006-10-01
DOP2006000005A (es) 2006-07-15
WO2006072580A1 (en) 2006-07-13
MX2007008300A (es) 2007-09-07
GT200600001A (es) 2006-08-22
PA8659101A1 (es) 2006-09-08
CA2594390C (en) 2013-10-22
JP5578765B2 (ja) 2014-08-27
UY29323A1 (es) 2006-10-02
EP1679082A1 (en) 2006-07-12
NZ554917A (en) 2010-01-29
KR20070092270A (ko) 2007-09-12
ZA200706533B (en) 2009-07-29
CA2594390A1 (en) 2006-07-13
NO20074036L (no) 2007-08-03
UA89976C2 (ru) 2010-03-25
CN101128218A (zh) 2008-02-20
EP1833513A1 (en) 2007-09-19
IL182499A0 (en) 2007-09-20
AR052190A1 (es) 2007-03-07
TW200635612A (en) 2006-10-16
AU2006204496A1 (en) 2006-07-13
PE20100449A1 (es) 2010-07-25

Similar Documents

Publication Publication Date Title
BRPI0606411A2 (pt) uso de corantes de cianina para o diagnóstico de doenças proliferativas
PA8790201A1 (es) Agentes citotóxicos que comprenden nuevos derivados de tomaimicina y su uso terapéutico
DOP2007000102A (es) Arilimidazolonas y ariltriazolona sustituidas asi como su uso
AR062448A1 (es) Conjugados de analogos de aziridinil-epotilona y composiciones farmaceuticas que comprenden los mismos
HN2008001103A (es) Agentes citotoxicos que comprenden nuevos derivados de tomaimicina
HN2008000360A (es) Dispersiones amorfas solidas
BR112015023333A2 (pt) pirrolobenzodiazepinas e conjugados das mesmas
HN2011001593A (es) Piridiloxi-indoles del vegf-r2 y uso de los mismos para el tratmiento de enfermedades
CR10842A (es) Derivados de acetileno y su uso para la union a placas amiloides y su diagnostico por imagenes
AR060880A1 (es) Uso de flibanserina para el tratamiento de trastornos posmenopausicos del deseo sexual
DOP2006000243A (es) Derivados de pirazina
BRPI0512928A (pt) composições e métodos para liberação de agentes de antitumor
HN2003000183A (es) Difenilazetidinonas sustituidas en anillo procedimiento para su preparacion, medicamentos que comprenden estos compuestos y su uso.
DOP2007000043A (es) Derivados de cromanol sustituidos y su uso
ES2525931T3 (es) Composiciones y métodos para prevenir o tratar enfermedad inflamatoria intestinal
PA8599401A1 (es) Nueva difenilazetidinona con propiedades fisiologicas mejoradas, procedimiento para su preparacion, medicamentos que comprenden este compuesto y su uso
DOP2006000280A (es) Nuevos derivados de furopirimidina acíclicos sustituidos y su uso
BRPI0620985B1 (pt) composição farmacêutica, e usos de derivados de triazina e sensibilizadores de insulina
AR062390A1 (es) Uso de derivados del 2,5-dihidroxibenceno para el tratamiento de hemangiomas o hemangioblastomas
UY31427A1 (es) Derivados 1,2,4-triazol amino como moduladores de mglur5
UY31903A (es) 7-sulfanilmetil-,7-silfinilmetil-y7-sulfonilmetilindoles sustituidos y el uso de los mismos
PA8657701A1 (es) Derivado de quinolina, su uso, preparacion y medicamento que lo contiene
UY32569A (es) Derivados punteados con sulfuro como moduladores de mglur5 733
ECSP099393A (es) Derivados de acetileno y su uso para la unión a placas amiloides y su diagnóstico por imágenes
GT200400212A (es) Agentes para la reduccion de peso

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE 6A. ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2178 DE 02/10/2012.