BRPI0606301A2 - processo para fabricar uma mistura de sais de acetato de polipeptìdeos, processo para fabricar uma mistura de sais de polipeptìdeos de trifluoroacetila não protegidos, mistura de sais de acetato de polipeptìdeos, composição farmacêutica, processos para a preparação de uma composição farmacêutica, e, mistura de polipeptìdeos de trifluoroacetila protegidos - Google Patents

processo para fabricar uma mistura de sais de acetato de polipeptìdeos, processo para fabricar uma mistura de sais de polipeptìdeos de trifluoroacetila não protegidos, mistura de sais de acetato de polipeptìdeos, composição farmacêutica, processos para a preparação de uma composição farmacêutica, e, mistura de polipeptìdeos de trifluoroacetila protegidos

Info

Publication number
BRPI0606301A2
BRPI0606301A2 BRPI0606301-2A BRPI0606301A BRPI0606301A2 BR PI0606301 A2 BRPI0606301 A2 BR PI0606301A2 BR PI0606301 A BRPI0606301 A BR PI0606301A BR PI0606301 A2 BRPI0606301 A2 BR PI0606301A2
Authority
BR
Brazil
Prior art keywords
mixture
polypeptide
salts
pharmaceutical composition
making
Prior art date
Application number
BRPI0606301-2A
Other languages
English (en)
Inventor
Ben-Zion Dolitzky
Original Assignee
Teva Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Pharma filed Critical Teva Pharma
Publication of BRPI0606301A2 publication Critical patent/BRPI0606301A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/02—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Transplantation (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polyamides (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PROCESSO PARA FABRICAR UMA MISTURA DE SAIS DE ACETATO DE POLIPEPTìDEOS, PROCESSO PARA FABRICAR UMA MISTURA DE SAIS DE POLIPETìDEOS DE TRIFLUOROACETILA NãO PROTEGIDOS, MISTURA DE SAIS DE ACETATO DE POLIPEPTìDEOS, COMPOSIçãO FARMACêUTICA, PROCESSOS PARA A PREPARAçãO DE UMA COMPOSIçãO FARMACêUTICA, E, MISTURA DE POLIPEPTìDEOS DE TRIFLUOROACETILA PROTEGIDOS. A presente invenção diz respeito a um processo melhorado para fabricar uma mistura de sais de acetatos de polipeptídeos, cada um dos quais consistindo de ácido glutâmico, alanina, tirosina e usina, para o uso no tratamento de esclerose múltipla.
BRPI0606301-2A 2005-02-02 2006-01-20 processo para fabricar uma mistura de sais de acetato de polipeptìdeos, processo para fabricar uma mistura de sais de polipeptìdeos de trifluoroacetila não protegidos, mistura de sais de acetato de polipeptìdeos, composição farmacêutica, processos para a preparação de uma composição farmacêutica, e, mistura de polipeptìdeos de trifluoroacetila protegidos BRPI0606301A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64944205P 2005-02-02 2005-02-02
PCT/US2006/002351 WO2006083608A1 (en) 2005-02-02 2006-01-20 Process for producing polypeptide mixtures using hydrogenolysis

Publications (1)

Publication Number Publication Date
BRPI0606301A2 true BRPI0606301A2 (pt) 2009-07-07

Family

ID=36777558

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0606301-2A BRPI0606301A2 (pt) 2005-02-02 2006-01-20 processo para fabricar uma mistura de sais de acetato de polipeptìdeos, processo para fabricar uma mistura de sais de polipeptìdeos de trifluoroacetila não protegidos, mistura de sais de acetato de polipeptìdeos, composição farmacêutica, processos para a preparação de uma composição farmacêutica, e, mistura de polipeptìdeos de trifluoroacetila protegidos

Country Status (16)

Country Link
US (1) US20060172942A1 (pt)
EP (1) EP1838326A4 (pt)
JP (1) JP2008528589A (pt)
KR (1) KR20070108388A (pt)
CN (1) CN101111252A (pt)
AU (1) AU2006211510B8 (pt)
BR (1) BRPI0606301A2 (pt)
CA (1) CA2594022A1 (pt)
IL (1) IL183610A0 (pt)
MX (1) MX2007009296A (pt)
NO (1) NO20074374L (pt)
NZ (1) NZ556156A (pt)
RU (1) RU2419638C2 (pt)
UA (1) UA93669C2 (pt)
WO (1) WO2006083608A1 (pt)
ZA (1) ZA200705874B (pt)

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Also Published As

Publication number Publication date
IL183610A0 (en) 2008-04-13
EP1838326A1 (en) 2007-10-03
NZ556156A (en) 2010-03-26
EP1838326A4 (en) 2009-09-30
AU2006211510B2 (en) 2011-03-10
AU2006211510B8 (en) 2011-04-21
RU2007132889A (ru) 2009-03-10
MX2007009296A (es) 2007-09-21
CN101111252A (zh) 2008-01-23
US20060172942A1 (en) 2006-08-03
UA93669C2 (ru) 2011-03-10
NO20074374L (no) 2007-10-24
JP2008528589A (ja) 2008-07-31
WO2006083608A1 (en) 2006-08-10
RU2419638C2 (ru) 2011-05-27
KR20070108388A (ko) 2007-11-09
ZA200705874B (en) 2009-04-29
CA2594022A1 (en) 2006-08-10
AU2006211510A1 (en) 2006-08-10

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