DK1848415T3 - Kombinationsterapi med glatirameracetat og rasagilin til behandling af multipel sklerose - Google Patents
Kombinationsterapi med glatirameracetat og rasagilin til behandling af multipel skleroseInfo
- Publication number
- DK1848415T3 DK1848415T3 DK06720863.7T DK06720863T DK1848415T3 DK 1848415 T3 DK1848415 T3 DK 1848415T3 DK 06720863 T DK06720863 T DK 06720863T DK 1848415 T3 DK1848415 T3 DK 1848415T3
- Authority
- DK
- Denmark
- Prior art keywords
- rasagiline
- treatment
- multiple sclerosis
- combination therapy
- glatiramer acetate
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US65401205P | 2005-02-17 | 2005-02-17 | |
PCT/US2006/005741 WO2006089164A1 (en) | 2005-02-17 | 2006-02-17 | Combination therapy with glatiramer acetate and rasagiline for the treatment of multiple sclerosis |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1848415T3 true DK1848415T3 (da) | 2013-07-08 |
Family
ID=36916800
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK06720863.7T DK1848415T3 (da) | 2005-02-17 | 2006-02-17 | Kombinationsterapi med glatirameracetat og rasagilin til behandling af multipel sklerose |
Country Status (12)
Country | Link |
---|---|
US (1) | US20080261894A1 (da) |
EP (1) | EP1848415B1 (da) |
CA (1) | CA2596664A1 (da) |
DK (1) | DK1848415T3 (da) |
ES (1) | ES2420404T3 (da) |
HR (1) | HRP20130622T1 (da) |
IL (1) | IL184037A0 (da) |
PL (1) | PL1848415T3 (da) |
PT (1) | PT1848415E (da) |
RS (1) | RS52867B (da) |
SI (1) | SI1848415T1 (da) |
WO (1) | WO2006089164A1 (da) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20100167983A1 (en) * | 2007-10-22 | 2010-07-01 | Teva Pharmaceutical Industries, Ltd. | Combination therapy with glatiramer acetate and rasagiline for the treatment of multiple sclerosis |
EP1987816A1 (de) * | 2007-04-30 | 2008-11-05 | Ratiopharm GmbH | Adsorbate eines Rasagilinsalzes mit einem wasserlöslichen Hilfsstoff |
US8080584B2 (en) * | 2009-01-23 | 2011-12-20 | Teva Pharmaceuticals Industries, Ltd. | Delayed release rasagiline citrate formulation |
EP3199172B1 (en) | 2009-08-20 | 2018-07-11 | Yeda Research and Development Co., Ltd. | Dosing regimen for multiple sclerosis |
EP2298277A1 (en) * | 2009-09-09 | 2011-03-23 | Labtec GmbH | Transdermal patch formulation |
USRE49251E1 (en) | 2010-01-04 | 2022-10-18 | Mapi Pharma Ltd. | Depot systems comprising glatiramer or pharmacologically acceptable salt thereof |
WO2011086470A1 (en) * | 2010-01-13 | 2011-07-21 | Ramot At Tel-Aviv University Ltd | Treatment of multiple sclerosis |
ES2602977T3 (es) | 2010-10-11 | 2017-02-23 | Teva Pharmaceutical Industries Ltd. | Biomarcadores de citocinas como biomarcadores predictivos de la respuesta clínica para acetato de glatirámero |
KR20140101730A (ko) | 2011-10-10 | 2014-08-20 | 테바 파마슈티컬 인더스트리즈 리미티드 | 글라티라머 아세테이트에 대한 임상 반응을 예측하는 데 유용한 단일 뉴클레오티드 다형성 |
CA2884267A1 (en) | 2012-10-10 | 2014-04-17 | Teva Pharmaceutical Industries Ltd. | Biomarkers predictive for clinical response for glatiramer acetate |
CA2895359A1 (en) * | 2012-12-21 | 2014-06-26 | Teva Pharmaceutical Industries Ltd. | Transmucosal delivery of glatiramer acetate |
UY35790A (es) | 2013-10-21 | 2015-05-29 | Teva Pharma | Marcadores genéticos que predicen la respuesta al acetato de glatiramer |
WO2015195605A1 (en) * | 2014-06-17 | 2015-12-23 | Teva Pharmaceutical Industries Ltd. | Transmucosal delivery of glatiramer acetate by oral patches |
US9155775B1 (en) | 2015-01-28 | 2015-10-13 | Teva Pharmaceutical Industries, Ltd. | Process for manufacturing glatiramer acetate product |
CA3050086A1 (en) | 2017-03-26 | 2018-10-04 | Mapi Pharma Ltd. | Glatiramer depot systems for treating progressive forms of multiple sclerosis |
Family Cites Families (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3201470A (en) * | 1965-08-17 | Chsx c cech | ||
US4529811A (en) * | 1981-03-02 | 1985-07-16 | G. D. Searle & Co. | Process for isolating organic compounds and lithium salt complexes useful in said process |
US5744500A (en) * | 1990-01-03 | 1998-04-28 | Teva Pharmaceutical Industries, Ltd. | Use of R-enantiomer of N-propargyl-1-aminoindan, salts, and compositions thereof |
IL92952A (en) * | 1990-01-03 | 1994-06-24 | Teva Pharma | R-enantiomers of n-propargyl-1-aminoindan compounds, their preparation and pharmaceutical compositions containing them |
US5444095A (en) * | 1991-04-04 | 1995-08-22 | University Of Toronto, Innovations Foundation | Use of deprenyl to rescue damaged nerve cells |
US5767164A (en) * | 1991-04-04 | 1998-06-16 | Innovations Foundation | Use of deprenyl to rescue damaged nerve cells |
IL112819A (en) * | 1991-10-16 | 2001-11-25 | Teva Pharma | Fluorinated 1-aminoindan compounds and a process for their preparation |
US5800808A (en) * | 1994-05-24 | 1998-09-01 | Veda Research And Development Co., Ltd. | Copolymer-1 improvements in compositions of copolymers |
IL115357A (en) * | 1995-09-20 | 2000-01-31 | Teva Pharma | Stable compositions containing N-propargyl-1-aminoindan and polyhydric alcohols |
IL118836A (en) * | 1996-07-11 | 2001-01-11 | Teva Pharma | Pharmaceutical compositions comprising s-(-)-n-propargyl-1-aminoindan |
ATE292619T1 (de) * | 1996-12-18 | 2005-04-15 | Teva Pharma | Aminoindanderivate |
US6214791B1 (en) * | 1997-01-10 | 2001-04-10 | Yeda Research And Development Co. Ltd. | Treatment of multiple sclerosis through ingestion or inhalation of copolymer-1 |
ES2527760T3 (es) * | 1998-07-23 | 2015-01-29 | Yeda Research And Development Co., Ltd. | Tratamiento de enfermedad de Crohn con copolímero 1 y polipéptidos |
WO2000005250A1 (en) * | 1998-07-23 | 2000-02-03 | Yeda Research And Development Co., Ltd | Treatment of autoimmune conditions with copolymer 1 and related copolymers and peptides |
US6800287B2 (en) * | 1998-09-25 | 2004-10-05 | Yeda Research And Development Co., Ltd. | Copolymer 1 related polypeptides for use as molecular weight markers and for therapeutic use |
US6514938B1 (en) * | 1998-09-25 | 2003-02-04 | Yeda Research And Development Co. Ltd. At The Weizmann Institute Of Science | Copolymer 1 related polypeptides for use as molecular weight markers and for therapeutic use |
JP4328050B2 (ja) * | 2000-01-20 | 2009-09-09 | イエダ リサーチ アンド デベロップメント カンパニー リミテッド | 神経保護療法のためのコポリマー1、関連ペプチド及びポリペプチドならびにそれらによって処理されたt細胞の使用 |
ZA200206457B (en) * | 2000-02-18 | 2003-08-13 | Yeda Res & Dev | Oral, nasal and pulmonary dosage formulations of copolymer 1. |
US20020077278A1 (en) * | 2000-06-05 | 2002-06-20 | Yong V. Wee | Use of glatiramer acetate (copolymer 1) in the treatment of central nervous system disorders |
WO2002076503A1 (en) * | 2000-06-20 | 2002-10-03 | Mayo Foundation For Medical Education And Research | Treatment of central nervous system diseases by antibodies against glatiramer acetate |
US20040013643A1 (en) * | 2000-09-19 | 2004-01-22 | Novlmmune S.A. | Methods for treatment of multiple sclerosis with statins |
ATE475883T1 (de) * | 2001-12-04 | 2010-08-15 | Teva Pharma | Verfahren zur messung der wirkstärke von glatirameracetat |
BR0307975A (pt) * | 2002-02-25 | 2005-01-11 | Elan Pharm Inc | Métodos para reduzir cronicamente a inflamação patológica em um paciente e para determinar a eficácia de um regime de administração crÈnica para tratar inflamação patológica em um indivìduo, composição e terapia combinada para tratamento crÈnico de inflamação patológica em um paciente e uso de um inibidor de alfa-4-integrina |
UA78854C2 (en) * | 2002-09-06 | 2007-04-25 | Kissei Pharmaceutical | Crystal for an oral solid drug and oral solid drug for dysuria treatment containing the same |
ES2588780T3 (es) * | 2002-11-15 | 2016-11-04 | Teva Pharmaceutical Industries Limited | Uso de rasagilina con o sin riluzol para el tratamiento de la esclerosis lateral amiotrófica |
CA2534711A1 (en) * | 2003-08-01 | 2005-02-10 | Medarex, Inc. | Combination therapies for multiple sclerosis |
WO2006014973A2 (en) * | 2004-07-26 | 2006-02-09 | Teva Pharmaceutical Industries, Ltd. | Pharmaceutical dosage forms including rasagiline |
SI2177528T1 (sl) * | 2004-09-09 | 2012-04-30 | Teva Pharma | Postopek za pripravo zmesi trifluoroacetil glatiramer acetata z uporabo očiščene bromovodikove kisline |
US7560100B2 (en) * | 2004-09-09 | 2009-07-14 | Yeda Research And Development Co., Ltd. | Mixtures of polypeptides, compositions containing and processes for preparing same, for treating neurodegenerative diseases |
CN101098685A (zh) * | 2004-11-24 | 2008-01-02 | 特瓦制药工业有限公司 | 雷沙吉兰经口崩解组合物 |
US20060172942A1 (en) * | 2005-02-02 | 2006-08-03 | Teva Pharmaceutical Industries, Ltd. | Process for producing polypeptide mixtures using hydrogenolysis |
CA2600011C (en) * | 2005-02-23 | 2015-11-10 | Teva Pharmaceutical Industries Ltd. | Rasagiline formulations of improved content uniformity |
EP1891233A4 (en) * | 2005-04-25 | 2010-03-24 | Yeda Res & Dev | MARKERS ASSOCIATED WITH THERAPY EFFECTIVENESS OF GLATIRAMERATE ACETATE |
CN101622225B (zh) * | 2005-11-17 | 2015-04-15 | 泰华制药工业有限公司 | 炔丙基氨基茚分离方法 |
US7572834B1 (en) * | 2005-12-06 | 2009-08-11 | Teva Pharmaceutical Industries, Ltd. | Rasagiline formulations and processes for their preparation |
MX2008012781A (es) * | 2006-04-03 | 2008-10-14 | Teva Pharma | Uso de rasagilina para el tratamiento de sindrome de piernas inquietas. |
EA016843B1 (ru) * | 2006-12-14 | 2012-07-30 | Тева Фармасьютикал Индастриз, Лтд. | Таннат разагилина |
MX2009006251A (es) * | 2006-12-14 | 2009-10-12 | Teva Pharma | Base de rasagilina solida cristalina. |
JP2011504925A (ja) * | 2007-11-28 | 2011-02-17 | テバ ファーマシューティカル インダストリーズ リミティド | 臨床的に確実な多発性硬化症の発症を遅延させる方法 |
-
2006
- 2006-02-17 SI SI200631607T patent/SI1848415T1/sl unknown
- 2006-02-17 ES ES06720863T patent/ES2420404T3/es active Active
- 2006-02-17 DK DK06720863.7T patent/DK1848415T3/da active
- 2006-02-17 PT PT67208637T patent/PT1848415E/pt unknown
- 2006-02-17 RS RS20130264A patent/RS52867B/en unknown
- 2006-02-17 WO PCT/US2006/005741 patent/WO2006089164A1/en active Application Filing
- 2006-02-17 CA CA002596664A patent/CA2596664A1/en not_active Abandoned
- 2006-02-17 US US11/884,633 patent/US20080261894A1/en not_active Abandoned
- 2006-02-17 PL PL06720863T patent/PL1848415T3/pl unknown
- 2006-02-17 EP EP06720863A patent/EP1848415B1/en active Active
-
2007
- 2007-06-19 IL IL184037A patent/IL184037A0/en unknown
-
2013
- 2013-07-02 HR HRP20130622TT patent/HRP20130622T1/hr unknown
Also Published As
Publication number | Publication date |
---|---|
HRP20130622T1 (en) | 2013-08-31 |
EP1848415A4 (en) | 2010-05-26 |
CA2596664A1 (en) | 2006-08-24 |
EP1848415A1 (en) | 2007-10-31 |
PL1848415T3 (pl) | 2013-10-31 |
PT1848415E (pt) | 2013-06-27 |
ES2420404T3 (es) | 2013-08-23 |
SI1848415T1 (sl) | 2013-08-30 |
EP1848415B1 (en) | 2013-04-03 |
WO2006089164A1 (en) | 2006-08-24 |
IL184037A0 (en) | 2008-12-29 |
US20080261894A1 (en) | 2008-10-23 |
RS52867B (en) | 2013-12-31 |
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