BRPI0519598A2 - derivados de cromano éteis como antagonistas de bomba de Ácido, composiÇço farmacÊutica e uso dos mesmos - Google Patents
derivados de cromano éteis como antagonistas de bomba de Ácido, composiÇço farmacÊutica e uso dos mesmosInfo
- Publication number
- BRPI0519598A2 BRPI0519598A2 BRPI0519598-5A BRPI0519598A BRPI0519598A2 BR PI0519598 A2 BRPI0519598 A2 BR PI0519598A2 BR PI0519598 A BRPI0519598 A BR PI0519598A BR PI0519598 A2 BRPI0519598 A2 BR PI0519598A2
- Authority
- BR
- Brazil
- Prior art keywords
- disease
- acid pump
- compounds
- pharmaceutical composition
- chroman derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
DERIVADOS DE CROMANO éTEIS COMO ANTAGONISTAS DE BOMBA DE ÁCIDO, COMPOSIÇçO FARMACÊUTICA E JSO DOS MESMOS. A presente invenção refere-se a compostos da fórmula (1): ou um sal farmaceuticamente aceitável dos mesmos, em que: R¹, R², Rü, R^ 4^, R^ 5^, R^ 6^, R^ 7^, R^ 8^ A e B são cada como descrito aqui ou um sal farmaceuticamente aceitável, e composições contendo tais compostos e o método de tratamento e o uso, compreendendo tais compostos para o tratamento de uma condição mediada por atividade antagonística de bomba de ácido tal como, porém não limitado a, como doença gastrointestinal, doença gastroesofágica, doença de refluxo gastroesofágica (GERD), úlcera péptica, úlcera gástrica, úlcera duodenal, úlceras induzidas por NSAID, gastrites, infecção de Helicobacter piloris, dispepsia, dispepsia funcional, síndrome de Zollinger-Ellison, doença de refluxo não erosiva (NERD), dor visceral, azia, náusea, esofagite, disfagia, hipersalivação, distúrbios da via aérea ou asma.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US63696304P | 2004-12-17 | 2004-12-17 | |
| US69577205P | 2005-06-29 | 2005-06-29 | |
| PCT/IB2005/003758 WO2006064339A1 (en) | 2004-12-17 | 2005-12-07 | Chromane derivatives useful as acid pump antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0519598A2 true BRPI0519598A2 (pt) | 2009-03-10 |
Family
ID=35995811
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0519598-5A BRPI0519598A2 (pt) | 2004-12-17 | 2005-12-07 | derivados de cromano éteis como antagonistas de bomba de Ácido, composiÇço farmacÊutica e uso dos mesmos |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US20090291977A1 (pt) |
| EP (1) | EP1838309B1 (pt) |
| JP (1) | JP2008524199A (pt) |
| KR (1) | KR20070086294A (pt) |
| AP (1) | AP2007004023A0 (pt) |
| AT (1) | ATE405262T1 (pt) |
| AU (1) | AU2005315303A1 (pt) |
| BR (1) | BRPI0519598A2 (pt) |
| CA (1) | CA2591412A1 (pt) |
| DE (1) | DE602005009257D1 (pt) |
| EA (1) | EA011512B1 (pt) |
| ES (1) | ES2313444T3 (pt) |
| IL (1) | IL183602A0 (pt) |
| MA (1) | MA29095B1 (pt) |
| MX (1) | MX2007007010A (pt) |
| NO (1) | NO20072764L (pt) |
| TN (1) | TNSN07227A1 (pt) |
| WO (1) | WO2006064339A1 (pt) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007026218A2 (en) * | 2005-09-01 | 2007-03-08 | Pfizer Japan Inc. | Chromane substituted 2-alkyl imidazopyridine derivatives and use thereof as acid pump antagonists |
| CA2645007A1 (en) * | 2006-03-17 | 2007-09-27 | Raqualia Pharma Inc. | Chromane derivatives |
| WO2008059373A1 (en) * | 2006-11-17 | 2008-05-22 | Raqualia Pharma Inc. | Imidazo [1, 2-a] pyrazine derivatives and their use as acid pump antagonists |
| CA2929858C (en) | 2013-11-22 | 2022-03-29 | CL BioSciences LLC | Gastrin antagonists (eg yf476, netazepide) for treatment and prevention of osteoporosis |
| JP6315708B2 (ja) * | 2015-06-22 | 2018-04-25 | 日本電信電話株式会社 | リチウム空気二次電池、リチウム空気二次電池の製造方法及びリチウム空気二次電池を備えた装置 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9801526D0 (sv) * | 1998-04-29 | 1998-04-29 | Astra Ab | New compounds |
| SE0102808D0 (sv) * | 2001-08-22 | 2001-08-22 | Astrazeneca Ab | New compounds |
| EP1565465A1 (en) * | 2002-11-19 | 2005-08-24 | ALTANA Pharma AG | 8-substituted imidazopyridines |
-
2005
- 2005-12-07 ES ES05818222T patent/ES2313444T3/es active Active
- 2005-12-07 US US11/721,453 patent/US20090291977A1/en not_active Abandoned
- 2005-12-07 CA CA002591412A patent/CA2591412A1/en not_active Abandoned
- 2005-12-07 AT AT05818222T patent/ATE405262T1/de not_active IP Right Cessation
- 2005-12-07 BR BRPI0519598-5A patent/BRPI0519598A2/pt not_active IP Right Cessation
- 2005-12-07 AP AP2007004023A patent/AP2007004023A0/xx unknown
- 2005-12-07 DE DE602005009257T patent/DE602005009257D1/de not_active Expired - Fee Related
- 2005-12-07 AU AU2005315303A patent/AU2005315303A1/en not_active Abandoned
- 2005-12-07 EA EA200701087A patent/EA011512B1/ru not_active IP Right Cessation
- 2005-12-07 JP JP2007546218A patent/JP2008524199A/ja active Pending
- 2005-12-07 MX MX2007007010A patent/MX2007007010A/es unknown
- 2005-12-07 EP EP05818222A patent/EP1838309B1/en active Active
- 2005-12-07 WO PCT/IB2005/003758 patent/WO2006064339A1/en active IP Right Grant
- 2005-12-07 KR KR1020077013608A patent/KR20070086294A/ko active IP Right Grant
-
2007
- 2007-05-31 IL IL183602A patent/IL183602A0/en unknown
- 2007-05-31 NO NO20072764A patent/NO20072764L/no not_active Application Discontinuation
- 2007-06-15 TN TNP2007000227A patent/TNSN07227A1/fr unknown
- 2007-06-15 MA MA29996A patent/MA29095B1/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2006064339A1 (en) | 2006-06-22 |
| MX2007007010A (es) | 2007-07-10 |
| EP1838309B1 (en) | 2008-08-20 |
| DE602005009257D1 (de) | 2008-10-02 |
| AP2007004023A0 (en) | 2007-06-30 |
| ATE405262T1 (de) | 2008-09-15 |
| EP1838309A1 (en) | 2007-10-03 |
| EA200701087A1 (ru) | 2008-02-28 |
| MA29095B1 (fr) | 2007-12-03 |
| NO20072764L (no) | 2007-07-03 |
| AU2005315303A1 (en) | 2006-06-22 |
| EA011512B1 (ru) | 2009-04-28 |
| ES2313444T3 (es) | 2009-03-01 |
| CA2591412A1 (en) | 2006-06-22 |
| KR20070086294A (ko) | 2007-08-27 |
| TNSN07227A1 (fr) | 2008-11-21 |
| IL183602A0 (en) | 2007-09-20 |
| US20090291977A1 (en) | 2009-11-26 |
| JP2008524199A (ja) | 2008-07-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BRPI0620081B8 (pt) | composto e composição farmacêutica. | |
| ATE442140T1 (de) | Chroman-substituierte benzimidazolderivate als säurepumpenantagonisten | |
| ATE512969T1 (de) | Benzimidazolderivate als selektive säurepumpenhemmer | |
| JP2009520017A5 (pt) | ||
| EE04279B1 (et) | Omeprasooli kristalne vorm | |
| NZ591793A (en) | Substituted 1-(4-fluoro-5-(2-fluoropyridin-3-yl)-1-((pyrindin-2-yl)sulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine compounds | |
| SE0301010D0 (sv) | Novel compounds | |
| BR0009952A (pt) | Composto, pró-droga, processo para produzir um composto, composição farmacêutica, método para antagonizar um receptor de adenosina a3, para inibir a p38 map quinase e a produção de tnf-alfa e para prevenir ou tratar doenças, e uso de um composto | |
| DK1537104T3 (da) | Azabicycloalkylethere og deres anvendelse som alfa7-nAChR-agonister | |
| NO20076006L (no) | Acetylenderivater | |
| BRPI0519598A2 (pt) | derivados de cromano éteis como antagonistas de bomba de Ácido, composiÇço farmacÊutica e uso dos mesmos | |
| MY139941A (en) | Indole derivatives | |
| ATE504570T1 (de) | Tartratsalz aus isofagomin und verwendungsverfahren dafür | |
| DE60020967D1 (de) | Kristalle von lansoprazole | |
| AR076798A1 (es) | Pirazinilpirazoles y composiciones que comprenden dichos compuestos | |
| WO2008050199A8 (en) | Substituted phenylmethyl bicyclocarboxyamide compounds | |
| NO20064240L (no) | Farmasoytiske forbindelser for oral administrasjon og fremgangsmate for fremstilling derav | |
| WO2007129066A8 (en) | 4- (2,6-dichloro-benzoylamino) -1h-pyrazole-3-carboxylic acid (1-methanesulphonyl-piperidin-4-yl) -amide for the treatment of cancer | |
| EA201000340A1 (ru) | Аминобензилзамещенные циклические сульфоны, полезные в качестве ингибиторов васе | |
| JP2008524199A5 (pt) | ||
| RU2006141255A (ru) | Соединение имидазопиридина | |
| WO2003027098A1 (fr) | Compose de benzymidazole, procede de production et d'utilisation de celui-ci | |
| UY30205A1 (es) | Derivados de cromano, sales del mismo farmacéuticamente aceptables, composiciones farmacéuticas conteniéndolos y aplicaciones | |
| WO2007072142A3 (en) | Benzimidazole-5-carboxamide derivatives | |
| WO2007026218A3 (en) | Chromane substituted 2-alkyl imidazopyridine derivatives and use thereof as acid pump antagonists |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B25A | Requested transfer of rights approved |
Owner name: RAQUALIA PHARMA INC. (JP) Free format text: TRANSFERIDO DE: PFIZER INC. |
|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 5A E 6A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: NAO APRESENTADA A GUIA DE CUMPRIMENTO DE EXIGENCIA. REFERENTE AS 5A E 6A ANUIDADES. |