BRPI0513272A - compostos orgánicos - Google Patents

compostos orgánicos

Info

Publication number
BRPI0513272A
BRPI0513272A BRPI0513272-0A BRPI0513272A BRPI0513272A BR PI0513272 A BRPI0513272 A BR PI0513272A BR PI0513272 A BRPI0513272 A BR PI0513272A BR PI0513272 A BRPI0513272 A BR PI0513272A
Authority
BR
Brazil
Prior art keywords
compounds
organic compounds
preparing
useful
processes
Prior art date
Application number
BRPI0513272-0A
Other languages
English (en)
Inventor
David Andrew Sandham
Christopher William Sharp
Simon James Watson
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of BRPI0513272A publication Critical patent/BRPI0513272A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/44—Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)

Abstract

COMPOSTOS ORGáNICOS A presente invenção refere-se a compostos de fórmula na forma livre ou na forma de sal, onde R¬ 1¬ e R¬ 2¬ têm os significados indicados no relatório descritivo, são úteis para tratar condições inflamatórias, em particular doenças inflamatórias ou obstrutivas das vias aéreas. Também estão descritas composições farmacêuticas que contêm os compostos e processos para preparar os compostos.
BRPI0513272-0A 2004-07-14 2005-07-13 compostos orgánicos BRPI0513272A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0415747.5A GB0415747D0 (en) 2004-07-14 2004-07-14 Organic compounds
PCT/EP2005/007634 WO2006005611A2 (en) 2004-07-14 2005-07-13 Glucocorticoid 16alpha,17.alpha.-isoxazolidines as anti-inflammatory agents

Publications (1)

Publication Number Publication Date
BRPI0513272A true BRPI0513272A (pt) 2008-05-06

Family

ID=32893551

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0513272-0A BRPI0513272A (pt) 2004-07-14 2005-07-13 compostos orgánicos

Country Status (12)

Country Link
US (1) US20070185172A1 (pt)
EP (1) EP1809648A2 (pt)
JP (1) JP2008506649A (pt)
KR (1) KR20070034056A (pt)
CN (1) CN101282987A (pt)
AU (1) AU2005261869B2 (pt)
BR (1) BRPI0513272A (pt)
CA (1) CA2573405A1 (pt)
GB (1) GB0415747D0 (pt)
MX (1) MX2007000506A (pt)
RU (1) RU2387664C2 (pt)
WO (1) WO2006005611A2 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101926805A (zh) * 2009-06-24 2010-12-29 天津金耀集团有限公司 一种含有16,17异恶唑烷类甾体化合物的药物组合物
CN102482318B (zh) * 2009-09-11 2015-11-25 奇斯药制品公司 异噁唑烷衍生物
TW201139369A (en) 2010-02-05 2011-11-16 Chiesi Farma Spa Pyrrolidine derivatives
EP2716648B1 (en) 2011-03-15 2017-06-14 CHIESI FARMACEUTICI S.p.A. Isoxazolidine derivatives
KR20140039161A (ko) 2011-03-15 2014-04-01 키에시 파르마슈티시 엣스. 피. 에이. 이소옥사졸리딘 유도체
KR20140042886A (ko) * 2011-08-01 2014-04-07 키에시 파르마슈티시 엣스. 피. 에이. 피롤리딘 고리를 갖는 16,17 위치에서 응축된 항염증용 스테로이드
PT3188759T (pt) 2014-09-03 2020-07-02 Rhizen Pharmaceuticals S A Método de tratamento e composições que compreende um inibidor duplo da quinase pi3k delta-gama e um corticosteroide

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3349084A (en) * 1965-05-17 1967-10-24 Upjohn Co Steroidal [16, 17-d]-2'-isoxazolines of the pregnane series
US4018774A (en) * 1976-02-13 1977-04-19 E. R. Squibb & Sons, Inc. Steroidal [16α,17-d]isoxazolidines
US4232013A (en) * 1977-12-03 1980-11-04 Lark S.P.A. 16,17-Pyrazolino- and 16,17-isopyrazolino-1,4-pregnadiene derivatives

Also Published As

Publication number Publication date
WO2006005611A3 (en) 2008-05-22
RU2387664C2 (ru) 2010-04-27
GB0415747D0 (en) 2004-08-18
RU2007105352A (ru) 2008-08-20
CN101282987A (zh) 2008-10-08
CA2573405A1 (en) 2006-01-19
EP1809648A2 (en) 2007-07-25
AU2005261869A1 (en) 2006-01-19
MX2007000506A (es) 2007-03-08
KR20070034056A (ko) 2007-03-27
US20070185172A1 (en) 2007-08-09
WO2006005611A2 (en) 2006-01-19
AU2005261869B2 (en) 2009-03-19
JP2008506649A (ja) 2008-03-06

Similar Documents

Publication Publication Date Title
BRPI0517455A (pt) compostos orgánicos
BRPI0515499A (pt) derivados de piridina para a inibição de estearoil-coa-desaturase humana
BRPI0514289A (pt) compostos orgánicos
BRPI0507034A (pt) compostos orgánicos
BRPI0410037A (pt) inibidores da fosfatidilinositol 3-cinase
BRPI0515577A (pt) compostos de carbonila que podem ser empregados como inibidores de fator xa de coagulação
WO2006113919A3 (en) Aryl alkyl acid derivatives for and use thereof
BRPI0410238A (pt) compostos orgánicos
BRPI0513272A (pt) compostos orgánicos
BRPI0517945A (pt) derivados de quinuclidina e seu uso como antagonistas de receptor muscarìnico m3
BRPI0516483A (pt) preparo e uso de derivados de ácido bifenil-4-il-carbonilamino para o tratamento de obesidade
CY1111327T1 (el) Υποκατεστημενα παραγωγα κυκλοεξυλοξεικου οξεος
BRPI0514841A (pt) inibidores de piridila da sinalização de hedgehog, processo de preparação dos mesmos e composição compreendendo os referidos inibidores
CY1112429T1 (el) Υποκατεστημενα παραγωγα σουλφοναμιδιου
TW200637863A (en) Organic compounds
BRPI0517032A (pt) compostos, processo para a sua manufatura, composições farmacêuticas que os compreendem, método para o tratamento e/ou prevenção de enfermidades e utilização desses compostos
BRPI0518907A2 (pt) compostos, processo para a sua manufatura, composiÇÕes farmacÊuticas que os compreendem, mÉtodo para o tratamento e/ou prevenÇço de enfermidades que estço associadas com a modulaÇço de receptores de h3 e sua utilizaÇço
BRPI0810719A8 (pt) Inibidores da enzima diacilglicerol o-acetiltansferase tipo 1
BRPI0715746B8 (pt) composto ou sal farmaceuticamente aceitável do mesmo e composição farmacêutica os compreendendo
BRPI0408444A (pt) derivados de 1-n-(fenil)-2-n-(fenil) pirazolidina-1,2-dicarboxamida como inibidores de fator xa de coagulação para o tratamento de trombose
CY1109569T1 (el) Υποκατεστημενα παραγωγα κυκλοεξανο-1,4-διαμινης
BRPI0411738A (pt) compostos orgánicos
BR0308419A (pt) Derivados de azetidina como antagonistas do receptor ccr-3
GB0602951D0 (en) Organic Compounds
BRPI0713951B8 (pt) derivados de quinazolina, e composição farmacêutica

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: CONFORME ARTIGO 10O DA RESOLUCAO 124/06, CABE SER ARQUIVADO REFERENTE AO NAO RECOLHIMENTO DA 6A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2143 DE 31/01/2012.