BRPI0512060A - compostos orgánicos - Google Patents

compostos orgánicos

Info

Publication number
BRPI0512060A
BRPI0512060A BRPI0512060-8A BRPI0512060A BRPI0512060A BR PI0512060 A BRPI0512060 A BR PI0512060A BR PI0512060 A BRPI0512060 A BR PI0512060A BR PI0512060 A BRPI0512060 A BR PI0512060A
Authority
BR
Brazil
Prior art keywords
organic compounds
compounds
nep
pharmaceuticals
processes
Prior art date
Application number
BRPI0512060-8A
Other languages
English (en)
Inventor
Kamlesh Bala
Catherine Leblanc
David Andrew Sandham
Katharine Louise Turner
Simon James Watson
Lyndon Nigel Brown
Brian Cox
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0413619A external-priority patent/GB0413619D0/en
Priority claimed from GB0507693A external-priority patent/GB0507693D0/en
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of BRPI0512060A publication Critical patent/BRPI0512060A/pt
Publication of BRPI0512060B1 publication Critical patent/BRPI0512060B1/pt
Publication of BRPI0512060B8 publication Critical patent/BRPI0512060B8/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Application Of Or Painting With Fluid Materials (AREA)

Abstract

COMPOSTOS ORGáNICOS. A presente invenção refere-se a compostos de fórmula (l), em forma livre ou de sal, em que R¬ ¹¬,R¬ ²¬, R¬ ³¬, R¬ 4¬, R¬ 5¬, R¬ 6¬, Q, W, X, m, n e p são tais como descritos no relatório descritivo, processos para a preparação deles, e o seu uso como produtos farmacêuticos.
BRPI0512060A 2004-06-17 2005-06-16 compostos orgânicos, composições farmacêuticas compreendendo os mesmos, bem como uso e processo de preparação dos referidos compostos BRPI0512060B8 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0413619.8 2004-06-17
GB0413619A GB0413619D0 (en) 2004-06-17 2004-06-17 Organic compounds
GB0507693.0 2005-04-15
GB0507693A GB0507693D0 (en) 2005-04-15 2005-04-15 Organic compounds
PCT/EP2005/006493 WO2005123731A2 (en) 2004-06-17 2005-06-16 Pyrrolopyridine derivatives and their use as crth2 antagonists

Publications (3)

Publication Number Publication Date
BRPI0512060A true BRPI0512060A (pt) 2008-02-06
BRPI0512060B1 BRPI0512060B1 (pt) 2018-08-07
BRPI0512060B8 BRPI0512060B8 (pt) 2021-05-25

Family

ID=35510318

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0512060A BRPI0512060B8 (pt) 2004-06-17 2005-06-16 compostos orgânicos, composições farmacêuticas compreendendo os mesmos, bem como uso e processo de preparação dos referidos compostos

Country Status (29)

Country Link
US (5) US7666878B2 (pt)
EP (1) EP1761529B3 (pt)
JP (1) JP4886680B2 (pt)
KR (1) KR101183330B1 (pt)
AR (1) AR049443A1 (pt)
AT (1) ATE378338T1 (pt)
AU (1) AU2005254681B2 (pt)
BR (1) BRPI0512060B8 (pt)
CA (1) CA2569125C (pt)
CY (1) CY1107851T1 (pt)
DE (1) DE602005003365T3 (pt)
DK (1) DK1761529T3 (pt)
EC (1) ECSP067077A (pt)
ES (1) ES2294717T7 (pt)
HK (1) HK1103730A1 (pt)
HR (1) HRP20080022T4 (pt)
IL (1) IL179604A (pt)
MA (1) MA28666B1 (pt)
MX (1) MXPA06014694A (pt)
MY (1) MY144903A (pt)
NO (1) NO338319B1 (pt)
NZ (1) NZ551439A (pt)
PE (1) PE20060301A1 (pt)
PL (1) PL1761529T6 (pt)
PT (1) PT1761529E (pt)
RS (1) RS50552B (pt)
RU (1) RU2379309C2 (pt)
TW (1) TWI352702B (pt)
WO (1) WO2005123731A2 (pt)

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GB0525143D0 (en) * 2005-12-09 2006-01-18 Novartis Ag Organic compounds
GB0525337D0 (en) * 2005-12-13 2006-01-18 Novartis Ag Organic compounds
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KR102279993B1 (ko) 2015-09-23 2021-07-21 엑스더블유파마 리미티드 감마-하이드록시부티르산의 전구체 및 이의 조성물 및 용도
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EP4076657A1 (en) 2019-12-20 2022-10-26 Nuevolution A/S Compounds active towards nuclear receptors
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Also Published As

Publication number Publication date
US20140309254A1 (en) 2014-10-16
US9169251B2 (en) 2015-10-27
MA28666B1 (fr) 2007-06-01
AR049443A1 (es) 2006-08-02
WO2005123731A2 (en) 2005-12-29
CA2569125C (en) 2013-01-08
DE602005003365D1 (de) 2011-01-05
TW200617009A (en) 2006-06-01
US20100204225A1 (en) 2010-08-12
KR101183330B1 (ko) 2012-09-17
CY1107851T1 (el) 2013-06-19
HK1103730A1 (en) 2007-12-28
IL179604A0 (en) 2007-05-15
JP4886680B2 (ja) 2012-02-29
TWI352702B (en) 2011-11-21
US7666878B2 (en) 2010-02-23
WO2005123731A3 (en) 2006-05-04
PL1761529T6 (pl) 2011-11-30
HRP20080022T3 (en) 2008-02-29
AU2005254681B2 (en) 2009-01-29
ES2294717T3 (es) 2008-04-01
DE602005003365T3 (de) 2012-08-30
ATE378338T1 (de) 2007-11-15
RU2379309C2 (ru) 2010-01-20
US20130267518A1 (en) 2013-10-10
DE602005003365T2 (de) 2008-09-11
AU2005254681A1 (en) 2005-12-29
HRP20080022T4 (hr) 2011-10-31
RU2007101277A (ru) 2008-07-27
ES2294717T7 (es) 2012-06-14
BRPI0512060B8 (pt) 2021-05-25
US8791256B2 (en) 2014-07-29
PE20060301A1 (es) 2006-05-18
DK1761529T3 (da) 2008-03-25
EP1761529B1 (en) 2007-11-14
KR20070032694A (ko) 2007-03-22
CA2569125A1 (en) 2005-12-29
EP1761529B3 (en) 2011-06-15
NO338319B1 (no) 2016-08-08
US8455645B2 (en) 2013-06-04
ECSP067077A (es) 2007-01-26
PL1761529T3 (pl) 2008-04-30
MXPA06014694A (es) 2007-02-12
NO20070323L (no) 2007-03-12
US20080114022A1 (en) 2008-05-15
US20100210610A1 (en) 2010-08-19
PT1761529E (pt) 2008-02-11
RS50552B (sr) 2010-05-07
BRPI0512060B1 (pt) 2018-08-07
MY144903A (en) 2011-11-30
US8470848B2 (en) 2013-06-25
JP2008502638A (ja) 2008-01-31
NZ551439A (en) 2009-09-25
EP1761529A2 (en) 2007-03-14
IL179604A (en) 2014-04-30

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