JOP20190223A1 - عملية لتحضير حمض 1-(4- ميثان سلفونيل -2- تراي فلورو ميثيل - بنزيل)-2- ميثيل -1h- بيرولو [2، 3-b] بيريدين -3- يل- أسيتيك - Google Patents

عملية لتحضير حمض 1-(4- ميثان سلفونيل -2- تراي فلورو ميثيل - بنزيل)-2- ميثيل -1h- بيرولو [2، 3-b] بيريدين -3- يل- أسيتيك

Info

Publication number
JOP20190223A1
JOP20190223A1 JOP/2019/0223A JOP20190223A JOP20190223A1 JO P20190223 A1 JOP20190223 A1 JO P20190223A1 JO P20190223 A JOP20190223 A JO P20190223A JO P20190223 A1 JOP20190223 A1 JO P20190223A1
Authority
JO
Jordan
Prior art keywords
pyrrolo
methanesulfonyl
pyridin
trifluoromethyl
benzyl
Prior art date
Application number
JOP/2019/0223A
Other languages
English (en)
Inventor
Philipp Lustenberger
Christian Mathes
Qiangbiao Pan
Benli Zou
Fabrice Gallou
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of JOP20190223A1 publication Critical patent/JOP20190223A1/ar

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J23/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
    • B01J23/38—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals
    • B01J23/40—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals of the platinum group metals
    • B01J23/44—Palladium
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J27/00—Catalysts comprising the elements or compounds of halogens, sulfur, selenium, tellurium, phosphorus or nitrogen; Catalysts comprising carbon compounds
    • B01J27/06—Halogens; Compounds thereof
    • B01J27/128—Halogens; Compounds thereof with iron group metals or platinum group metals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

يتعلق الاختراع الحالي بعمليات جديدة لتخليق حمض [1-(4- ميثان سلفونيل -2- تراي فلورو ميثيل - بنزيل)-2- ميثيل -1H- بيرولو [2، 3-b] بيريدين -3- يل]- أسيتيك وبمركبات وسيطة حيث يتم استخدامها في هذه العمليات.
JOP/2019/0223A 2017-04-01 2017-06-16 عملية لتحضير حمض 1-(4- ميثان سلفونيل -2- تراي فلورو ميثيل - بنزيل)-2- ميثيل -1h- بيرولو [2، 3-b] بيريدين -3- يل- أسيتيك JOP20190223A1 (ar)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN2017079244 2017-04-01

Publications (1)

Publication Number Publication Date
JOP20190223A1 true JOP20190223A1 (ar) 2019-09-26

Family

ID=62111133

Family Applications (1)

Application Number Title Priority Date Filing Date
JOP/2019/0223A JOP20190223A1 (ar) 2017-04-01 2017-06-16 عملية لتحضير حمض 1-(4- ميثان سلفونيل -2- تراي فلورو ميثيل - بنزيل)-2- ميثيل -1h- بيرولو [2، 3-b] بيريدين -3- يل- أسيتيك

Country Status (11)

Country Link
US (1) US10723735B2 (ar)
EP (1) EP3606924A1 (ar)
JP (1) JP2020515553A (ar)
KR (1) KR20190134622A (ar)
CN (1) CN110461840A (ar)
AU (1) AU2018242613B2 (ar)
CA (1) CA3054266A1 (ar)
IL (1) IL268765B (ar)
JO (1) JOP20190223A1 (ar)
RU (1) RU2756507C2 (ar)
WO (1) WO2018178926A1 (ar)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7382798B2 (ja) * 2018-11-07 2023-11-17 国立大学法人 東京大学 極性基含有オレフィン共重合体、及び極性基含有オレフィン共重合体組成物
JP7382797B2 (ja) * 2018-11-07 2023-11-17 国立大学法人 東京大学 極性基含有オレフィン重合体の製造方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY144903A (en) 2004-06-17 2011-11-30 Novartis Ag Pyrrolopyridine derivatives and their use as crth2 antagonists
GB0413619D0 (en) * 2004-06-17 2004-07-21 Novartis Ag Organic compounds
GB0525337D0 (en) * 2005-12-13 2006-01-18 Novartis Ag Organic compounds
WO2009049021A1 (en) * 2007-10-10 2009-04-16 Chemietek, Llc Heterocyclic compounds as crth2 receptor antagonists
WO2016005577A1 (en) 2014-07-11 2016-01-14 Intervet International B.V. Use of anthelmintic agents against dirofilaria immitis
AU2016330264A1 (en) * 2015-09-29 2018-03-22 Novartis Ag Process for preparing 1-(4-Methanesulfonyl-2-trifluoromethyl-benzyl)-2-methyl-1H-pyrrolo [2,3-b]pyridin-3-yl-acetic acid
CN106188040B (zh) * 2016-06-28 2018-03-23 浙江宏鑫染化材料有限公司 一种Fevipiprant及其中间体的制备方法

Also Published As

Publication number Publication date
EP3606924A1 (en) 2020-02-12
US10723735B2 (en) 2020-07-28
AU2018242613A1 (en) 2019-09-05
IL268765A (en) 2019-10-31
RU2756507C2 (ru) 2021-10-01
KR20190134622A (ko) 2019-12-04
RU2019130495A3 (ar) 2021-07-20
CN110461840A (zh) 2019-11-15
RU2019130495A (ru) 2021-05-05
CA3054266A1 (en) 2018-10-04
JP2020515553A (ja) 2020-05-28
IL268765B (en) 2021-09-30
AU2018242613B2 (en) 2020-07-02
US20200031824A1 (en) 2020-01-30
WO2018178926A1 (en) 2018-10-04

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