BRPI0509747A - gens pufa-pks de ulkenia - Google Patents
gens pufa-pks de ulkeniaInfo
- Publication number
- BRPI0509747A BRPI0509747A BRPI0509747-9A BRPI0509747A BRPI0509747A BR PI0509747 A BRPI0509747 A BR PI0509747A BR PI0509747 A BRPI0509747 A BR PI0509747A BR PI0509747 A BRPI0509747 A BR PI0509747A
- Authority
- BR
- Brazil
- Prior art keywords
- pks
- ulkenia
- gens
- puff
- sequences
- Prior art date
Links
- 241001491678 Ulkenia Species 0.000 title abstract 2
- 108010030975 Polyketide Synthases Proteins 0.000 abstract 3
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 2
- 235000020777 polyunsaturated fatty acids Nutrition 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 230000002255 enzymatic effect Effects 0.000 abstract 1
- 230000009261 transgenic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6436—Fatty acid esters
- C12P7/6445—Glycerides
- C12P7/6472—Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Abstract
GENES PUFA-PKS DE ULKENIA. A presente invenção refere-se genes que codificam seqüências específicas para síntases poliquetídeas (PKS). A PKS assim sintetizada à Caracterizada por sua capacidade enzimática de produzir PUFAs (ácidos graxos poiliinsaturados). A invenção abrange, além disso, a identificação das seqüências de DNA correspondentes bem como o uso das seqüências de nucleotídeos para a preparação de organismos recombinantes ou transgênicos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102004017370A DE102004017370A1 (de) | 2004-04-08 | 2004-04-08 | PUFA-PKS Gene aus Ulkenia |
PCT/EP2005/003701 WO2005097982A2 (de) | 2004-04-08 | 2005-04-08 | Pufa-pks gene aus ulkenia |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0509747A true BRPI0509747A (pt) | 2007-09-25 |
Family
ID=35062272
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0509747-9A BRPI0509747A (pt) | 2004-04-08 | 2005-04-08 | gens pufa-pks de ulkenia |
Country Status (11)
Country | Link |
---|---|
US (1) | US7939305B2 (pt) |
EP (1) | EP1733029A2 (pt) |
JP (2) | JP2007532104A (pt) |
KR (2) | KR101484097B1 (pt) |
CN (2) | CN101087882A (pt) |
AU (1) | AU2005231964B2 (pt) |
BR (1) | BRPI0509747A (pt) |
CA (1) | CA2563427A1 (pt) |
DE (1) | DE102004017370A1 (pt) |
IL (1) | IL178613A0 (pt) |
WO (1) | WO2005097982A2 (pt) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5340742A (en) | 1988-09-07 | 1994-08-23 | Omegatech Inc. | Process for growing thraustochytrium and schizochytrium using non-chloride salts to produce a microfloral biomass having omega-3-highly unsaturated fatty acids |
US8003772B2 (en) | 1999-01-14 | 2011-08-23 | Martek Biosciences Corporation | Chimeric PUFA polyketide synthase systems and uses thereof |
KR20090064603A (ko) * | 2000-01-28 | 2009-06-19 | 마텍 바이오싸이언스스 코포레이션 | 발효기 내에서 진핵 미생물의 고밀도 배양에 의한 고도불포화 지방산을 함유하는 지질의 증진된 생산 방법 |
CA3056110C (en) | 2004-04-22 | 2020-07-14 | Surinder Pal Singh | Synthesis of long-chain polyunsaturated fatty acids by recombinant cells |
DK1756280T3 (en) | 2004-04-22 | 2015-02-02 | Commw Scient Ind Res Org | SYNTHESIS OF CHAIN, polyunsaturated fatty acids BY RECOMBINANT CELLS |
CA2647150A1 (en) | 2006-03-15 | 2007-09-20 | Martek Biosciences Corporation | Plant seed oils containing polyunsaturated fatty acids |
EP2059588A4 (en) | 2006-08-29 | 2010-07-28 | Commw Scient Ind Res Org | FATTY ACID SYNTHESIS |
ES2644883T3 (es) | 2008-11-18 | 2017-11-30 | Commonwealth Scientific And Industrial Research Organisation | Enzimas y métodos para producir ácidos grasos omega-3 |
CN102741267B (zh) | 2009-03-19 | 2020-06-23 | 帝斯曼知识产权资产有限公司 | 多不饱和脂肪酸合酶核酸分子和多肽,及其组合物、制备方法和用途 |
CN103415611B (zh) | 2010-10-01 | 2016-08-10 | 国立大学法人九州大学 | 原生藻菌的转化方法 |
US8816111B2 (en) | 2012-06-15 | 2014-08-26 | Commonwealth Scientific And Industrial Research Organisation | Lipid comprising polyunsaturated fatty acids |
CN111154724B (zh) | 2013-12-18 | 2024-02-06 | 联邦科学技术研究组织 | 包含二十二碳六烯酸的提取的植物脂质 |
WO2015196250A1 (en) | 2014-06-27 | 2015-12-30 | Commonwealth Scientific And Industrial Research Organisation | Lipid comprising docosapentaenoic acid |
EP3099782B1 (en) | 2014-01-28 | 2019-03-20 | DSM IP Assets B.V. | Factors for the production and accumulation of polyunsaturated fatty acids (pufas) derived from pufa synthases |
CA2977271A1 (en) * | 2015-03-02 | 2016-09-09 | Synthetic Genomics, Inc. | Regulatory elements from labyrinthulomycetes microorganisms |
CA3017225A1 (en) | 2016-03-16 | 2017-09-21 | Synthetic Genomics, Inc. | Production of proteins in labyrinthulomycetes |
CN109477079A (zh) | 2016-05-12 | 2019-03-15 | 帝斯曼知识产权资产管理有限公司 | 增加微藻中ω-3多不饱和脂肪酸产量的方法 |
JOP20170154B1 (ar) | 2016-08-01 | 2023-03-28 | Omeros Corp | تركيبات وطرق لتثبيط masp-3 لعلاج أمراض واضطرابات مختلفة |
US10633454B2 (en) | 2016-11-01 | 2020-04-28 | Conagen Inc. | Expression of modified glycoproteins and glycopeptides |
WO2018219171A1 (zh) * | 2017-05-31 | 2018-12-06 | 厦门汇盛生物有限公司 | 一株生产dha和epa的细菌、该细菌基因组中的6个基因片段及它们的应用 |
CN108753810B (zh) * | 2018-05-22 | 2021-06-18 | 昆明理工大学 | 一种转录调节蛋白基因orf2的用途 |
JPWO2020032258A1 (ja) * | 2018-08-10 | 2021-08-12 | 協和発酵バイオ株式会社 | 多価不飽和脂肪酸を生産する微生物及び多価不飽和脂肪酸の製造法 |
CN112601808A (zh) * | 2018-08-10 | 2021-04-02 | 协和发酵生化株式会社 | 生产二十碳五烯酸的微生物和二十碳五烯酸的制造方法 |
CN110577921B (zh) * | 2019-05-28 | 2021-04-02 | 浙江工业大学 | 产两性霉素b的重组结节链霉菌及其应用 |
CN114107074B (zh) * | 2021-11-18 | 2024-04-09 | 厦门大学 | 一种过表达3-酮酰基合酶基因的裂殖壶菌基因工程菌株的构建方法及其应用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5798259A (en) * | 1992-05-15 | 1998-08-25 | Sagami Chemical Research Center | Gene coding for eicosapentaenoic acid synthesizing enzymes and process for production of eicosapentaenoic acid |
EP2280062A3 (en) * | 1996-03-28 | 2011-09-28 | DSM IP Assets B.V. | Preparation of microbial polyunsaturated fatty acid containing oil from pasteurised biomass |
US6566583B1 (en) * | 1997-06-04 | 2003-05-20 | Daniel Facciotti | Schizochytrium PKS genes |
TWI426126B (zh) * | 2001-04-16 | 2014-02-11 | Dsm Ip Assets Bv | 多不飽和脂肪酸(pufa)聚乙醯合成酶系統及其用途(二) |
-
2004
- 2004-04-08 DE DE102004017370A patent/DE102004017370A1/de not_active Withdrawn
-
2005
- 2005-04-08 AU AU2005231964A patent/AU2005231964B2/en not_active Ceased
- 2005-04-08 KR KR1020067023437A patent/KR101484097B1/ko not_active IP Right Cessation
- 2005-04-08 CN CNA2005800188787A patent/CN101087882A/zh active Pending
- 2005-04-08 KR KR1020137020015A patent/KR20130114225A/ko not_active Application Discontinuation
- 2005-04-08 US US11/547,921 patent/US7939305B2/en not_active Expired - Fee Related
- 2005-04-08 EP EP05751638A patent/EP1733029A2/de not_active Ceased
- 2005-04-08 CA CA002563427A patent/CA2563427A1/en not_active Abandoned
- 2005-04-08 CN CN201410175661.8A patent/CN103981156A/zh active Pending
- 2005-04-08 BR BRPI0509747-9A patent/BRPI0509747A/pt not_active IP Right Cessation
- 2005-04-08 JP JP2007506732A patent/JP2007532104A/ja active Pending
- 2005-04-08 WO PCT/EP2005/003701 patent/WO2005097982A2/de active Application Filing
-
2006
- 2006-10-15 IL IL178613A patent/IL178613A0/en unknown
-
2012
- 2012-07-27 JP JP2012167374A patent/JP2012205595A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
DE102004017370A1 (de) | 2005-10-27 |
AU2005231964B2 (en) | 2012-03-08 |
US20090093033A1 (en) | 2009-04-09 |
CA2563427A1 (en) | 2005-10-20 |
IL178613A0 (en) | 2007-02-11 |
CN103981156A (zh) | 2014-08-13 |
AU2005231964A1 (en) | 2005-10-20 |
WO2005097982A2 (de) | 2005-10-20 |
WO2005097982A3 (de) | 2007-04-05 |
KR20130114225A (ko) | 2013-10-16 |
KR20070056002A (ko) | 2007-05-31 |
JP2012205595A (ja) | 2012-10-25 |
EP1733029A2 (de) | 2006-12-20 |
CN101087882A (zh) | 2007-12-12 |
JP2007532104A (ja) | 2007-11-15 |
US7939305B2 (en) | 2011-05-10 |
KR101484097B1 (ko) | 2015-01-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] | ||
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |