BRPI0506791A - método para imitar uma resposta à insulina de primeira fase refeição-relacionada fisiológica em diabetes do tipo 2 - Google Patents
método para imitar uma resposta à insulina de primeira fase refeição-relacionada fisiológica em diabetes do tipo 2Info
- Publication number
- BRPI0506791A BRPI0506791A BRPI0506791-0A BRPI0506791A BRPI0506791A BR PI0506791 A BRPI0506791 A BR PI0506791A BR PI0506791 A BRPI0506791 A BR PI0506791A BR PI0506791 A BRPI0506791 A BR PI0506791A
- Authority
- BR
- Brazil
- Prior art keywords
- insulin
- administration
- levels
- type
- diabetes
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Medicinal Chemistry (AREA)
- Endocrinology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53594504P | 2004-01-12 | 2004-01-12 | |
| PCT/US2005/000596 WO2005067964A1 (en) | 2004-01-12 | 2005-01-10 | A method of reducing serum proinsulin levels in type 2 diabetics |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0506791A true BRPI0506791A (pt) | 2007-05-22 |
Family
ID=34794375
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0506791-0A BRPI0506791A (pt) | 2004-01-12 | 2005-01-10 | método para imitar uma resposta à insulina de primeira fase refeição-relacionada fisiológica em diabetes do tipo 2 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20050153874A1 (enExample) |
| EP (1) | EP1708738B1 (enExample) |
| JP (1) | JP2007517892A (enExample) |
| KR (2) | KR20060110353A (enExample) |
| CN (1) | CN101027082A (enExample) |
| AU (2) | AU2005204378B2 (enExample) |
| BR (1) | BRPI0506791A (enExample) |
| ES (1) | ES2584867T3 (enExample) |
| IL (1) | IL176699A (enExample) |
| NZ (1) | NZ548980A (enExample) |
| WO (1) | WO2005067964A1 (enExample) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6428771B1 (en) * | 1995-05-15 | 2002-08-06 | Pharmaceutical Discovery Corporation | Method for drug delivery to the pulmonary system |
| EP2280004B1 (en) | 1999-06-29 | 2016-04-20 | MannKind Corporation | Pharmaceutical formulations comprising insulin complexed with a diketopiperazine |
| US9006175B2 (en) * | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
| US6923175B2 (en) | 2002-03-20 | 2005-08-02 | Mannkind Corporation | Inhalation apparatus |
| US7338171B2 (en) * | 2003-10-27 | 2008-03-04 | Jen-Chuen Hsieh | Method and apparatus for visual drive control |
| US20070027063A1 (en) * | 2004-01-12 | 2007-02-01 | Mannkind Corporation | Method of preserving the function of insulin-producing cells |
| PL2319500T3 (pl) * | 2004-03-12 | 2013-05-31 | Biodel Inc | Szybko działające kompozycje do dostarczania leku |
| US20080248999A1 (en) * | 2007-04-04 | 2008-10-09 | Biodel Inc. | Amylin formulations |
| US20080090753A1 (en) * | 2004-03-12 | 2008-04-17 | Biodel, Inc. | Rapid Acting Injectable Insulin Compositions |
| CN101010305B (zh) | 2004-08-20 | 2010-08-11 | 曼金德公司 | 二酮哌嗪合成的催化反应 |
| BR122019022692B1 (pt) | 2004-08-23 | 2023-01-10 | Mannkind Corporation | Composição terapêutica em pó seco contendo dicetopiperazina, pelo menos um tipo de cátion e um agente biologicamente ativo |
| AU2006213084A1 (en) * | 2005-01-10 | 2006-08-17 | Mannkind Corporation | Methods and compositions for minimizing accrual of inhalable insulin in the lungs |
| ES2439455T3 (es) * | 2005-08-01 | 2014-01-23 | Mannkind Corporation | Procedimiento de preservar la función de las células productoras de insulina |
| KR101384456B1 (ko) * | 2005-09-14 | 2014-04-10 | 맨카인드 코포레이션 | 활성제에 대한 결정질 미립자 표면의 친화력의 증가를 기반으로 하는 약물 제제화의 방법 |
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| US7713929B2 (en) | 2006-04-12 | 2010-05-11 | Biodel Inc. | Rapid acting and long acting insulin combination formulations |
| US8084420B2 (en) * | 2005-09-29 | 2011-12-27 | Biodel Inc. | Rapid acting and long acting insulin combination formulations |
| ES2647080T3 (es) | 2006-02-22 | 2017-12-19 | Mannkind Corporation | Un método para mejorar las propiedades farmacéuticas de micropartículas que comprenden dicetopiperazina y un agente activo |
| WO2007121256A2 (en) * | 2006-04-12 | 2007-10-25 | Biodel, Inc. | Rapid acting and long acting insulin combination formulations |
| US8785396B2 (en) | 2007-10-24 | 2014-07-22 | Mannkind Corporation | Method and composition for treating migraines |
| WO2011163272A1 (en) | 2010-06-21 | 2011-12-29 | Mannkind Corporation | Dry powder drug delivery system and methods |
| AU2009204309B2 (en) * | 2008-01-04 | 2012-11-22 | Biodel, Inc. | Insulin formulations for insulin release as a function of tissue glucose levels |
| US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
| DK2293833T3 (en) | 2008-06-13 | 2016-05-23 | Mannkind Corp | DRY POWDER INHALER AND MEDICINAL ADMINISTRATION SYSTEM |
| CA2728523C (en) | 2008-06-20 | 2020-03-10 | Mannkind Corporation | An interactive apparatus and method for real-time profiling of inhalation efforts |
| TWI532497B (zh) | 2008-08-11 | 2016-05-11 | 曼凱公司 | 超快起作用胰島素之用途 |
| US11110151B2 (en) * | 2008-08-11 | 2021-09-07 | Mannkind Corporation | Composition and method for reducing hypoglycemia events in diabetes treatment |
| US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
| SI2379100T1 (sl) * | 2009-01-08 | 2015-02-27 | Mannkind Corporation | Zdravljenje hiperglikemije z GLP-1 |
| US9060927B2 (en) * | 2009-03-03 | 2015-06-23 | Biodel Inc. | Insulin formulations for rapid uptake |
| CA2754595C (en) | 2009-03-11 | 2017-06-27 | Mannkind Corporation | Apparatus, system and method for measuring resistance of an inhaler |
| US8551528B2 (en) | 2009-06-12 | 2013-10-08 | Mannkind Corporation | Diketopiperazine microparticles with defined specific surface areas |
| JP5784622B2 (ja) | 2009-11-03 | 2015-09-24 | マンカインド コーポレ−ション | 吸入活動をシミュレートするための装置及び方法 |
| ES2625858T3 (es) | 2011-04-01 | 2017-07-20 | Mannkind Corporation | Paquete de tipo blíster para cartuchos farmacéuticos |
| WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
| HK1201475A1 (en) | 2011-10-24 | 2015-09-04 | Mannkind Corporation | Methods and compositions for treating pain |
| CA3098386C (en) | 2012-07-12 | 2022-11-29 | Mannkind Corporation | Dry powder drug delivery systems and methods |
| EP2911690A1 (en) | 2012-10-26 | 2015-09-02 | MannKind Corporation | Inhalable influenza vaccine compositions and methods |
| MX369136B (es) | 2013-03-15 | 2019-10-30 | Mannkind Corp | Composiciones de dicetopiperazina microcristalina y metodos. |
| BR122019026637B1 (pt) | 2013-07-18 | 2023-09-26 | Mannkind Corporation | Formulações farmacêuticas de pó seco e método para a fabricação de uma formulação de pó seco |
| US11446127B2 (en) | 2013-08-05 | 2022-09-20 | Mannkind Corporation | Insufflation apparatus and methods |
| WO2015148905A1 (en) | 2014-03-28 | 2015-10-01 | Mannkind Corporation | Use of ultrarapid acting insulin |
| US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
| CN110187123B (zh) * | 2019-05-06 | 2022-07-22 | 天津医科大学总医院 | 一种糖尿病早期诊断生物标志物及其应用 |
| CN111235036B (zh) * | 2020-01-15 | 2022-03-18 | 西北大学 | 一种冠突散囊菌及从其中分离纯化二酮哌嗪二聚体的方法 |
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-
2005
- 2005-01-10 NZ NZ548980A patent/NZ548980A/en not_active IP Right Cessation
- 2005-01-10 JP JP2006549451A patent/JP2007517892A/ja active Pending
- 2005-01-10 KR KR1020067013980A patent/KR20060110353A/ko not_active Ceased
- 2005-01-10 EP EP05711314.4A patent/EP1708738B1/en not_active Expired - Lifetime
- 2005-01-10 WO PCT/US2005/000596 patent/WO2005067964A1/en not_active Ceased
- 2005-01-10 CN CNA200580002306XA patent/CN101027082A/zh active Pending
- 2005-01-10 AU AU2005204378A patent/AU2005204378B2/en not_active Ceased
- 2005-01-10 ES ES05711314.4T patent/ES2584867T3/es not_active Expired - Lifetime
- 2005-01-10 BR BRPI0506791-0A patent/BRPI0506791A/pt not_active Application Discontinuation
- 2005-01-10 US US11/032,278 patent/US20050153874A1/en not_active Abandoned
- 2005-01-10 KR KR1020097017808A patent/KR100985126B1/ko not_active Expired - Fee Related
-
2006
- 2006-07-04 IL IL176699A patent/IL176699A/en not_active IP Right Cessation
-
2009
- 2009-03-06 AU AU2009200894A patent/AU2009200894B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| KR20060110353A (ko) | 2006-10-24 |
| AU2009200894B2 (en) | 2010-11-18 |
| JP2007517892A (ja) | 2007-07-05 |
| CA2552707C (en) | 2018-03-27 |
| AU2009200894A1 (en) | 2009-03-26 |
| ES2584867T3 (es) | 2016-09-29 |
| NZ548980A (en) | 2009-10-30 |
| WO2005067964A1 (en) | 2005-07-28 |
| EP1708738B1 (en) | 2016-05-04 |
| CA2552707A1 (en) | 2005-07-28 |
| IL176699A (en) | 2011-11-30 |
| AU2005204378B2 (en) | 2009-01-22 |
| KR20090096756A (ko) | 2009-09-14 |
| US20050153874A1 (en) | 2005-07-14 |
| KR100985126B1 (ko) | 2010-10-05 |
| CN101027082A (zh) | 2007-08-29 |
| AU2005204378A1 (en) | 2005-07-28 |
| EP1708738A1 (en) | 2006-10-11 |
| IL176699A0 (en) | 2006-10-31 |
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