IL176699A - Use of insulin in the preparation of a medicament for mimicking a physiological meal-related first phase insulin response and reducing a risk factor for atherosclerosis in type 2 diabetics - Google Patents

Use of insulin in the preparation of a medicament for mimicking a physiological meal-related first phase insulin response and reducing a risk factor for atherosclerosis in type 2 diabetics

Info

Publication number
IL176699A
IL176699A IL176699A IL17669906A IL176699A IL 176699 A IL176699 A IL 176699A IL 176699 A IL176699 A IL 176699A IL 17669906 A IL17669906 A IL 17669906A IL 176699 A IL176699 A IL 176699A
Authority
IL
Israel
Prior art keywords
insulin
medicament
levels
meal
serum
Prior art date
Application number
IL176699A
Other languages
English (en)
Other versions
IL176699A0 (en
Original Assignee
Mannkind Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mannkind Corp filed Critical Mannkind Corp
Publication of IL176699A0 publication Critical patent/IL176699A0/en
Publication of IL176699A publication Critical patent/IL176699A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL176699A 2004-01-12 2006-07-04 Use of insulin in the preparation of a medicament for mimicking a physiological meal-related first phase insulin response and reducing a risk factor for atherosclerosis in type 2 diabetics IL176699A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US53594504P 2004-01-12 2004-01-12
PCT/US2005/000596 WO2005067964A1 (en) 2004-01-12 2005-01-10 A method of reducing serum proinsulin levels in type 2 diabetics

Publications (2)

Publication Number Publication Date
IL176699A0 IL176699A0 (en) 2006-10-31
IL176699A true IL176699A (en) 2011-11-30

Family

ID=34794375

Family Applications (1)

Application Number Title Priority Date Filing Date
IL176699A IL176699A (en) 2004-01-12 2006-07-04 Use of insulin in the preparation of a medicament for mimicking a physiological meal-related first phase insulin response and reducing a risk factor for atherosclerosis in type 2 diabetics

Country Status (11)

Country Link
US (1) US20050153874A1 (enExample)
EP (1) EP1708738B1 (enExample)
JP (1) JP2007517892A (enExample)
KR (2) KR100985126B1 (enExample)
CN (1) CN101027082A (enExample)
AU (2) AU2005204378B2 (enExample)
BR (1) BRPI0506791A (enExample)
ES (1) ES2584867T3 (enExample)
IL (1) IL176699A (enExample)
NZ (1) NZ548980A (enExample)
WO (1) WO2005067964A1 (enExample)

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CN104436170B (zh) 2004-08-23 2018-02-23 曼金德公司 用于药物输送的二酮哌嗪盐
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JP5421362B2 (ja) 2008-06-13 2014-02-19 マンカインド コーポレイション 薬物送達用の乾燥粉末吸入器およびシステム
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RU2470681C2 (ru) 2008-06-20 2012-12-27 Маннкайнд Корпорейшн Интерактивное устройство и способ профилирования усилий при ингаляции в реальном масштабе времени
TWI614024B (zh) 2008-08-11 2018-02-11 曼凱公司 超快起作用胰島素之用途
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EP2496295A1 (en) 2009-11-03 2012-09-12 MannKind Corporation An apparatus and method for simulating inhalation efforts
JP6385673B2 (ja) 2010-06-21 2018-09-05 マンカインド コーポレイション 乾燥粉末薬物送達システム
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WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
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AU2013289957B2 (en) 2012-07-12 2017-02-23 Mannkind Corporation Dry powder drug delivery systems and methods
WO2014066856A1 (en) 2012-10-26 2014-05-01 Mannkind Corporation Inhalable influenza vaccine compositions and methods
ES2754388T3 (es) 2013-03-15 2020-04-17 Mannkind Corp Composiciones y métodos de dicetopiperazina microcristalina
AU2014290438B2 (en) 2013-07-18 2019-11-07 Mannkind Corporation Heat-stable dry powder pharmaceutical compositions and methods
JP2016530930A (ja) 2013-08-05 2016-10-06 マンカインド コーポレイション 通気装置及び方法
WO2015148905A1 (en) 2014-03-28 2015-10-01 Mannkind Corporation Use of ultrarapid acting insulin
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Also Published As

Publication number Publication date
CA2552707C (en) 2018-03-27
IL176699A0 (en) 2006-10-31
KR100985126B1 (ko) 2010-10-05
NZ548980A (en) 2009-10-30
KR20060110353A (ko) 2006-10-24
AU2005204378A1 (en) 2005-07-28
CA2552707A1 (en) 2005-07-28
US20050153874A1 (en) 2005-07-14
JP2007517892A (ja) 2007-07-05
WO2005067964A1 (en) 2005-07-28
AU2009200894B2 (en) 2010-11-18
EP1708738A1 (en) 2006-10-11
KR20090096756A (ko) 2009-09-14
ES2584867T3 (es) 2016-09-29
AU2005204378B2 (en) 2009-01-22
CN101027082A (zh) 2007-08-29
BRPI0506791A (pt) 2007-05-22
EP1708738B1 (en) 2016-05-04
AU2009200894A1 (en) 2009-03-26

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