BRPI0506148A - preparação farmacêutica para o tratamento de choque - Google Patents

preparação farmacêutica para o tratamento de choque

Info

Publication number
BRPI0506148A
BRPI0506148A BRPI0506148-2A BRPI0506148A BRPI0506148A BR PI0506148 A BRPI0506148 A BR PI0506148A BR PI0506148 A BRPI0506148 A BR PI0506148A BR PI0506148 A BRPI0506148 A BR PI0506148A
Authority
BR
Brazil
Prior art keywords
sub
moiety
peptide
pharmaceutical preparation
bbeta
Prior art date
Application number
BRPI0506148-2A
Other languages
English (en)
Inventor
Peter Petzelbauer
Kai Zacharowski
Original Assignee
Fibrex Medical Res & Dev Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AT0108704A external-priority patent/AT414097B/de
Priority claimed from AT0004005A external-priority patent/AT501263B1/de
Application filed by Fibrex Medical Res & Dev Gmbh filed Critical Fibrex Medical Res & Dev Gmbh
Publication of BRPI0506148A publication Critical patent/BRPI0506148A/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36Blood coagulation or fibrinolysis factors
    • A61K38/363Fibrinogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Cardiology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

"PREPARAçãO FARMACêUTICA PARA O TRATAMENTO DE CHOQUE". A invenção refere-se ao uso de um peptídeo da fórmula geral I, em que R~ 1~ e R~ 2~, sendo iguais ou diferentes, denotam hidrogênio, uma porção de hidrocarboneto saturado ou insaturado compreendendo de 1 a 10, em particular de 1 a 3, átomos de carbono, Z~ 1~ denota uma porção de histidina ou prolina, Z~ 2~ denota uma porção de arginina, uma porção de peptídeo ou uma porção de proteína compreendendo uma porção de arginina inicial, em particular compreendendo de 2 a 30 aminoácidos, peptídeo este que tem a propriedade biológica de emparelhar o motivo de ligação de VE-caderina indutível na cadeia B<225> (isto é, B<225>~ 15-42~) da fibrina humana, para a preparação de uma preparação farmacêutica para o tratamento de choque.
BRPI0506148-2A 2004-06-25 2005-06-24 preparação farmacêutica para o tratamento de choque BRPI0506148A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AT0108704A AT414097B (de) 2004-06-25 2004-06-25 Pharmazeutische zubereitung zur behandlung von schock
AT0004005A AT501263B1 (de) 2005-01-13 2005-01-13 Pharmazeutische zubereitung zur behandlung von schock
PCT/AT2005/000228 WO2006000007A1 (de) 2004-06-25 2005-06-24 Verwendung von peptiden, die aus der a alpha oder der b beta kette des humanen fibrinogens abgeleitet wurden, zur behandlung von schock

Publications (1)

Publication Number Publication Date
BRPI0506148A true BRPI0506148A (pt) 2006-10-24

Family

ID=35058593

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0506148-2A BRPI0506148A (pt) 2004-06-25 2005-06-24 preparação farmacêutica para o tratamento de choque

Country Status (20)

Country Link
US (1) US20080249006A1 (pt)
EP (1) EP1691827B1 (pt)
JP (1) JP2008503503A (pt)
AT (1) ATE439856T1 (pt)
AU (1) AU2005256121B2 (pt)
BR (1) BRPI0506148A (pt)
CA (1) CA2544676A1 (pt)
CY (1) CY1109631T1 (pt)
DE (1) DE502005007926D1 (pt)
DK (1) DK1691827T3 (pt)
EA (1) EA008799B1 (pt)
ES (1) ES2331958T3 (pt)
HK (1) HK1093308A1 (pt)
HR (1) HRP20090618T1 (pt)
IL (1) IL173969A (pt)
NZ (1) NZ545634A (pt)
PL (1) PL1691827T3 (pt)
PT (1) PT1691827E (pt)
SI (1) SI1691827T1 (pt)
WO (1) WO2006000007A1 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT502987A1 (de) * 2005-12-23 2007-07-15 Fibrex Medical Res & Dev Gmbh Pharmazeutische zusammensetzung zur behandlung von hämorrhagischem schock und seinen folgeerscheinungen
CN101389653A (zh) * 2006-02-23 2009-03-18 菲布雷克斯医疗研究及开发有限责任公司 肽和肽衍生物以及含有它们的药物组合物
WO2007095659A1 (de) * 2006-02-23 2007-08-30 Fibrex Medical Research & Development Gmbh Peptide und peptid-derivate, herstellun derselben sowie deren verwendung zur herstellung eines therapeutisch und/oder präventiv wirkenden arzneimittels
ZA200807027B (en) 2006-02-23 2009-12-30 Fibrex Medical Res & Dev Gmbh Peptides and peptide derivatives, the production thereof as well as their use for preparing a therapeutically and/or preventively active pharmaceutical composition
EP2193370A2 (en) * 2007-09-24 2010-06-09 Fibrex Medical Research & Development GmbH Methods of screening for compounds having anti-inflammatory activity
WO2009096502A1 (ja) * 2008-01-31 2009-08-06 Japan As Represented By President Of National Center Of Neurology And Psychiatry うつ病およびうつ状態のマーカーおよびそれを用いた検出・診断
US7884074B2 (en) 2008-05-15 2011-02-08 Ikaria Development Subsidiary Two, LLC Compounds and methods for prevention and/or treatment of inflammation using the same
US8088890B2 (en) * 2008-09-26 2012-01-03 Fibrex Medical Research & Development Gmbh Peptides and peptidomimetic compounds, the manufacturing thereof as well as their use for preparing a therapeutically and/or preventively active pharmaceutical composition
WO2010043444A2 (en) * 2008-10-15 2010-04-22 Fibrex Medical Research & Development Gmbh Pharmaceutical preparation for the treatment and/or prevention of ischemia/reperfusion injury and the sequels thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5965107A (en) * 1992-03-13 1999-10-12 Diatide, Inc. Technetium-99m labeled peptides for imaging
DE19729591A1 (de) * 1997-07-10 1999-02-11 Therasorb Medizinische Systeme Mittel zur Behandlung und/oder Prophylaxe von Mikrozirkulationsstörungen
YU53803A (sh) * 2000-12-12 2006-03-03 Fibrex Medical Research & Development Gmbh. Peptidi i/ili proteini kao i njihova primena za pripremanje terapeutskih i/ili preventivnih lekova
WO2002069960A2 (en) * 2001-03-06 2002-09-12 Axxima Pharmaceuticals Ag Use of mek inhibitors for treating inflammation and virus induced hemorrhagic shock
CN101389653A (zh) * 2006-02-23 2009-03-18 菲布雷克斯医疗研究及开发有限责任公司 肽和肽衍生物以及含有它们的药物组合物

Also Published As

Publication number Publication date
HK1093308A1 (en) 2007-03-02
PL1691827T3 (pl) 2010-01-29
AU2005256121B2 (en) 2011-03-03
IL173969A0 (en) 2006-07-05
AU2005256121A8 (en) 2008-08-21
CA2544676A1 (en) 2006-01-05
US20080249006A1 (en) 2008-10-09
AU2005256121A1 (en) 2006-04-27
JP2008503503A (ja) 2008-02-07
DK1691827T3 (da) 2009-12-14
NZ545634A (en) 2009-09-25
PT1691827E (pt) 2009-11-23
SI1691827T1 (sl) 2010-01-29
ES2331958T3 (es) 2010-01-21
EP1691827A1 (de) 2006-08-23
HRP20090618T1 (hr) 2010-01-31
EA200600561A1 (ru) 2006-08-25
WO2006000007A1 (de) 2006-01-05
ATE439856T1 (de) 2009-09-15
EA008799B1 (ru) 2007-08-31
EP1691827B1 (de) 2009-08-19
CY1109631T1 (el) 2014-08-13
IL173969A (en) 2011-06-30
DE502005007926D1 (de) 2009-10-01

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AO NAO RECOLHIMENTO DA 8A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2208 DE 30/04/2013.