BRPI0418482A - processo para o preparo de l-aminoácidos com amplificação do gene zwf - Google Patents

processo para o preparo de l-aminoácidos com amplificação do gene zwf

Info

Publication number
BRPI0418482A
BRPI0418482A BRPI0418482-3A BRPI0418482A BRPI0418482A BR PI0418482 A BRPI0418482 A BR PI0418482A BR PI0418482 A BRPI0418482 A BR PI0418482A BR PI0418482 A BRPI0418482 A BR PI0418482A
Authority
BR
Brazil
Prior art keywords
preparing
amino acids
gene amplification
zwf gene
amino acid
Prior art date
Application number
BRPI0418482-3A
Other languages
English (en)
Inventor
Stephan Hans
Brigitte Bathe
Alexander Reth
Georg Thierbach
Caroline Kreutzer
Bettina Hodrich
Original Assignee
Degussa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Degussa filed Critical Degussa
Publication of BRPI0418482A publication Critical patent/BRPI0418482A/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/345Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Brevibacterium (G)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0006Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/06Alanine; Leucine; Isoleucine; Serine; Homoserine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/08Lysine; Diaminopimelic acid; Threonine; Valine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/22Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
    • C12P13/227Tryptophan
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y101/00Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01049Glucose-6-phosphate dehydrogenase (1.1.1.49)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

PROCESSO PARA O PREPARO DE L-AMINOáCIDOS COM AMPLIFICAçãO DE GENE zwf. A presente invenção refere-se a um processo para o preparo de L-aminoácidos por meio de fermentação de bactérias corineformes, o qual compreende realização das seguintes etapas: a) fermentação das bactérias que produzem L-aminoácido nas quais pelo menos o gene zwf é amplificado. b) concentração do L-aminoácido no meio ou nas células das bactérias e c) isolamento do L-aminoácido produzido.
BRPI0418482-3A 2004-01-29 2004-01-29 processo para o preparo de l-aminoácidos com amplificação do gene zwf BRPI0418482A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2004/000775 WO2005075631A1 (en) 2004-01-29 2004-01-29 Process for the preparation of l-amino acids with amplification of the zwf gene

Publications (1)

Publication Number Publication Date
BRPI0418482A true BRPI0418482A (pt) 2007-06-19

Family

ID=34833862

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0418482-3A BRPI0418482A (pt) 2004-01-29 2004-01-29 processo para o preparo de l-aminoácidos com amplificação do gene zwf

Country Status (4)

Country Link
EP (1) EP1709166A1 (pt)
CN (1) CN1906291A (pt)
BR (1) BRPI0418482A (pt)
WO (1) WO2005075631A1 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10155505A1 (de) * 2001-11-13 2003-05-22 Basf Ag Gene die für Glucose-6-Phosphat-Dehydrogenase Proteine codieren
DE102006026328A1 (de) * 2006-06-02 2008-01-03 Evonik Degussa Gmbh Verfahren zur Herstellung eines L-Lysin enthaltenden Futtermitteladditivs
CN103789341B (zh) * 2014-01-23 2016-05-18 河北工业大学 一种酿酒酵母异丁醇高产菌株的构建方法
CN109423504B (zh) * 2017-08-24 2022-10-04 廊坊梅花生物技术开发有限公司 生产l-色氨酸的菌株及用途
CN113637699B (zh) * 2020-04-27 2023-05-30 中国科学院分子植物科学卓越创新中心 一种提高氨基酸产生菌生产能力的方法
CN114107141B (zh) * 2021-08-19 2022-07-12 中国科学院天津工业生物技术研究所 高产l-脯氨酸的谷氨酸棒杆菌以及高产l-脯氨酸的方法
CN114181288B (zh) * 2022-02-17 2022-05-03 北京中科伊品生物科技有限公司 制备l-缬氨酸的方法及其所用的基因与该基因编码的蛋白质

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060014259A9 (en) * 1999-07-09 2006-01-19 Kevin Burke Process for the preparation of L-amino acids with amplification of the zwf gene
US20030175911A1 (en) * 2000-03-20 2003-09-18 Stephen Hans Process for the preparation of L-amino acids with amplification of the zwf gene

Also Published As

Publication number Publication date
WO2005075631A1 (en) 2005-08-18
CN1906291A (zh) 2007-01-31
EP1709166A1 (en) 2006-10-11

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal acc. article 33 of ipl - extension of time limit for request of examination expired