BRPI0418095A - inibidores de quinases dependentes de ciclina, composições e usos relacionados aos mesmos - Google Patents
inibidores de quinases dependentes de ciclina, composições e usos relacionados aos mesmosInfo
- Publication number
- BRPI0418095A BRPI0418095A BRPI0418095-0A BRPI0418095A BRPI0418095A BR PI0418095 A BRPI0418095 A BR PI0418095A BR PI0418095 A BRPI0418095 A BR PI0418095A BR PI0418095 A BRPI0418095 A BR PI0418095A
- Authority
- BR
- Brazil
- Prior art keywords
- dependent kinase
- cyclin
- kinase inhibitors
- compositions
- uses related
- Prior art date
Links
- 229940043378 cyclin-dependent kinase inhibitor Drugs 0.000 title abstract 3
- 239000002875 cyclin dependent kinase inhibitor Substances 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 102000016736 Cyclin Human genes 0.000 abstract 1
- 108050006400 Cyclin Proteins 0.000 abstract 1
- 230000022131 cell cycle Effects 0.000 abstract 1
- 230000006369 cell cycle progression Effects 0.000 abstract 1
- 230000004663 cell proliferation Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000001419 dependent effect Effects 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 229940043355 kinase inhibitor Drugs 0.000 abstract 1
- JTJMJGYZQZDUJJ-UHFFFAOYSA-N phencyclidine Chemical compound C1CCCCN1C1(C=2C=CC=CC=2)CCCCC1 JTJMJGYZQZDUJJ-UHFFFAOYSA-N 0.000 abstract 1
- 239000003757 phosphotransferase inhibitor Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53187203P | 2003-12-23 | 2003-12-23 | |
| US56013804P | 2004-04-06 | 2004-04-06 | |
| US61648004P | 2004-10-06 | 2004-10-06 | |
| PCT/US2004/043492 WO2005063765A1 (en) | 2003-12-23 | 2004-12-21 | Inhibitors of cyclin-dependent kinases, compositions and uses related thereto |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0418095A true BRPI0418095A (pt) | 2007-04-17 |
Family
ID=34743691
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0418095-0A BRPI0418095A (pt) | 2003-12-23 | 2004-12-21 | inibidores de quinases dependentes de ciclina, composições e usos relacionados aos mesmos |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US8097619B2 (https=) |
| EP (1) | EP1709051A1 (https=) |
| JP (1) | JP4791975B2 (https=) |
| KR (1) | KR101155883B1 (https=) |
| AU (1) | AU2004309415B2 (https=) |
| BR (1) | BRPI0418095A (https=) |
| CA (1) | CA2551640C (https=) |
| EA (1) | EA013117B1 (https=) |
| IL (1) | IL176543A0 (https=) |
| MX (1) | MXPA06007399A (https=) |
| NO (1) | NO20063186L (https=) |
| WO (1) | WO2005063765A1 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013075199A1 (pt) | 2011-11-25 | 2013-05-30 | Universidade Federal De Santa Catarina | "compostos acil-hidrazonas e oxadiazóis, composições farmacêuticas compreendendo os mesmos e seus usos |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2298291A3 (en) * | 2004-06-18 | 2011-08-03 | Agennix USA Inc. | Kinase inhibitors for treating cancers |
| EP2019101A1 (en) | 2007-07-26 | 2009-01-28 | GPC Biotech AG | Pyrazol[3,4-d]pyrimidin-4-one useful as Kinase Inhibitor |
| US8822447B2 (en) | 2010-04-22 | 2014-09-02 | Janssen Pharmaceutica Nv | Indazole compounds useful as ketohexokinase inhibitors |
| CA3043288A1 (en) | 2016-11-30 | 2018-06-07 | Oncotyrol Center For Personalized Cancer Medicine Gmbh | 3-amino-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-ones as cyclin dependent kinase inhibitors |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3211732A (en) | 1965-10-12 | Pyrazolob:x-d]pyrlil/hdines | ||
| CH398626A (de) | 1960-05-11 | 1966-03-15 | Ciba Geigy | Verfahren zur Herstellung neuer Pyrazolopyrimidine |
| JPS60130521A (ja) | 1983-12-19 | 1985-07-12 | Morishita Seiyaku Kk | 抗癌剤 |
| US4678499A (en) | 1985-03-11 | 1987-07-07 | E. I. Du Pont De Nemours And Company | Herbicidal sulfonamides |
| JPS6299361A (ja) | 1985-10-25 | 1987-05-08 | Morishita Seiyaku Kk | インデノ〔１，２−ｃ〕ピラゾ−ル誘導体 |
| TW370529B (en) | 1992-12-17 | 1999-09-21 | Pfizer | Pyrazolopyrimidines |
| US5593997A (en) | 1995-05-23 | 1997-01-14 | Pfizer Inc. | 4-aminopyrazolo(3-,4-D)pyrimidine and 4-aminopyrazolo-(3,4-D)pyridine tyrosine kinase inhibitors |
| US5866702A (en) | 1996-08-02 | 1999-02-02 | Cv Therapeutics, Incorporation | Purine inhibitors of cyclin dependent kinase 2 |
| US6407103B2 (en) * | 1998-04-21 | 2002-06-18 | Bristol-Myers Squibb Pharma Company | Indeno [1,2-c] pyrazol-4-ones and their uses |
| JP4665239B2 (ja) | 1998-04-21 | 2011-04-06 | アゲンニクス アーゲー | 抗癌剤および抗増殖性薬剤としての５−アミノインデノ［１，２−ｃ］ピラゾール−４−オン |
| US6559152B2 (en) | 1998-10-13 | 2003-05-06 | Dupont Pharmaceuticals Company | 6-substituted pyrazolo[3,4-d]pyrimidin-4-ones useful as cyclin dependent kinase inhibitors |
| US6531477B1 (en) | 1998-10-13 | 2003-03-11 | Dupont Pharmaceuticals Company | 6-substituted pyrazolo [3,4-d] pyrimidin-4-ones useful as cyclin dependent kinase inhibitors |
| US6291504B1 (en) | 1999-10-20 | 2001-09-18 | Dupont Pharmaceuticals Company | Acylsemicarbazides and their uses |
| AU2001212168A1 (en) | 2000-10-20 | 2002-05-06 | Bristol-Myers Squibb Pharma Company | Acylsemicarbazides and their use as cyclin dependent kinase (CDK) inhibitors |
| US6491971B2 (en) | 2000-11-15 | 2002-12-10 | G.T. Equipment Technologies, Inc | Release coating system for crucibles |
| WO2002044174A2 (en) | 2000-12-01 | 2002-06-06 | Bristol-Myers Squibb Pharma Company | 3-(2,4-dimethylthiazol-5-yl) indeno[1,2-c]pyrazol-4-one derivatives as cdk inhibitors |
| US7605175B2 (en) * | 2001-03-02 | 2009-10-20 | Gpc Biotech Ag | Inhibitors of cyclin-dependent kinases, compositions and uses related thereto |
| ATE497603T1 (de) | 2001-03-02 | 2011-02-15 | Gpc Biotech Ag | Drei-hybrid-assaysystem |
| EP1404670A4 (en) | 2001-07-06 | 2004-11-24 | Bristol Myers Squibb Pharma Co | SEMICARBAZIDES AND THEIR USE |
| AU2002365211A1 (en) | 2001-07-10 | 2003-09-02 | Bristol-Myers Squibb Pharma Company | 6-substituted pyrazolo (3,4-d) pyrimidin-4-ones useful as cyclin dependent kinase inhibitors |
| EP1832589A1 (en) | 2001-10-15 | 2007-09-12 | GPC Biotech Inc. | Inhibitors of cyclin-dependent kinases,compositions and uses related thereto |
| US6753329B2 (en) | 2001-12-03 | 2004-06-22 | Gpc Biotech Inc. | Inhibitors of cyclin-dependent kinases, compositions and uses related thereto |
-
2004
- 2004-12-21 EP EP04815554A patent/EP1709051A1/en not_active Withdrawn
- 2004-12-21 WO PCT/US2004/043492 patent/WO2005063765A1/en not_active Ceased
- 2004-12-21 EA EA200601216A patent/EA013117B1/ru not_active IP Right Cessation
- 2004-12-21 KR KR1020067014820A patent/KR101155883B1/ko not_active Expired - Fee Related
- 2004-12-21 US US10/584,485 patent/US8097619B2/en not_active Expired - Fee Related
- 2004-12-21 MX MXPA06007399A patent/MXPA06007399A/es active IP Right Grant
- 2004-12-21 CA CA2551640A patent/CA2551640C/en not_active Expired - Fee Related
- 2004-12-21 AU AU2004309415A patent/AU2004309415B2/en not_active Ceased
- 2004-12-21 JP JP2006547427A patent/JP4791975B2/ja not_active Expired - Fee Related
- 2004-12-21 BR BRPI0418095-0A patent/BRPI0418095A/pt not_active IP Right Cessation
-
2006
- 2006-06-25 IL IL176543A patent/IL176543A0/en unknown
- 2006-07-10 NO NO20063186A patent/NO20063186L/no not_active Application Discontinuation
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013075199A1 (pt) | 2011-11-25 | 2013-05-30 | Universidade Federal De Santa Catarina | "compostos acil-hidrazonas e oxadiazóis, composições farmacêuticas compreendendo os mesmos e seus usos |
Also Published As
| Publication number | Publication date |
|---|---|
| EA200601216A1 (ru) | 2006-12-29 |
| KR101155883B1 (ko) | 2012-06-20 |
| US8097619B2 (en) | 2012-01-17 |
| JP2007516296A (ja) | 2007-06-21 |
| AU2004309415A1 (en) | 2005-07-14 |
| JP4791975B2 (ja) | 2011-10-12 |
| AU2004309415B2 (en) | 2010-08-26 |
| KR20060130624A (ko) | 2006-12-19 |
| HK1101399A1 (zh) | 2007-10-18 |
| EP1709051A1 (en) | 2006-10-11 |
| NO20063186L (no) | 2006-09-20 |
| IL176543A0 (en) | 2006-10-05 |
| MXPA06007399A (es) | 2007-01-26 |
| CA2551640C (en) | 2012-09-11 |
| WO2005063765A1 (en) | 2005-07-14 |
| EA013117B1 (ru) | 2010-02-26 |
| US20090209530A1 (en) | 2009-08-20 |
| CA2551640A1 (en) | 2005-07-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B25D | Requested change of name of applicant approved |
Owner name: AGENNIX USA INC. (US) Free format text: NOME ALTERADO DE: GPC BIOTECH, INC. |
|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 9A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2260 DE 29/04/2014. |