BRPI0410341B8 - conjugados de polissacarídeo-proteína derivatizados de meningococos multivalentes e vacina - Google Patents
conjugados de polissacarídeo-proteína derivatizados de meningococos multivalentes e vacinaInfo
- Publication number
- BRPI0410341B8 BRPI0410341B8 BRPI0410341A BRPI0410341A BRPI0410341B8 BR PI0410341 B8 BRPI0410341 B8 BR PI0410341B8 BR PI0410341 A BRPI0410341 A BR PI0410341A BR PI0410341 A BRPI0410341 A BR PI0410341A BR PI0410341 B8 BRPI0410341 B8 BR PI0410341B8
- Authority
- BR
- Brazil
- Prior art keywords
- polysaccharide
- derivatized
- protein conjugates
- meningococci
- multivalent
- Prior art date
Links
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 102000014914 Carrier Proteins Human genes 0.000 abstract 1
- 108010078791 Carrier Proteins Proteins 0.000 abstract 1
- 241000588650 Neisseria meningitidis Species 0.000 abstract 1
- 150000004676 glycans Chemical class 0.000 abstract 1
- 230000036039 immunity Effects 0.000 abstract 1
- 230000003053 immunization Effects 0.000 abstract 1
- 230000005923 long-lasting effect Effects 0.000 abstract 1
- 229920001282 polysaccharide Polymers 0.000 abstract 1
- 239000005017 polysaccharide Substances 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6081—Albumin; Keyhole limpet haemocyanin [KLH]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46858103P | 2003-05-07 | 2003-05-07 | |
| US60/468,581 | 2003-05-07 | ||
| PCT/US2004/014466 WO2004103400A2 (en) | 2003-05-07 | 2004-05-07 | Multivalent meningococcal derivatized polysaccharide-protein conjugates and corresponding vaccines |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BRPI0410341A BRPI0410341A (pt) | 2006-05-30 |
| BRPI0410341B1 BRPI0410341B1 (pt) | 2019-07-16 |
| BRPI0410341B8 true BRPI0410341B8 (pt) | 2021-05-25 |
Family
ID=33476662
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0410341A BRPI0410341B8 (pt) | 2003-05-07 | 2004-05-07 | conjugados de polissacarídeo-proteína derivatizados de meningococos multivalentes e vacina |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20050002957A1 (https=) |
| EP (2) | EP2386313A1 (https=) |
| JP (3) | JP2006528936A (https=) |
| CN (2) | CN1852733A (https=) |
| AU (2) | AU2004240558A1 (https=) |
| BR (1) | BRPI0410341B8 (https=) |
| CA (1) | CA2524860C (https=) |
| WO (1) | WO2004103400A2 (https=) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9928196D0 (en) | 1999-11-29 | 2000-01-26 | Chiron Spa | Combinations of B, C and other antigens |
| GB0227346D0 (en) | 2002-11-22 | 2002-12-31 | Chiron Spa | 741 |
| ES2461350T3 (es) | 2003-01-30 | 2014-05-19 | Novartis Ag | Vacunas inyectables contra múltiples serogrupos de meningococos |
| GB0406013D0 (en) * | 2004-03-17 | 2004-04-21 | Chiron Srl | Analysis of saccharide vaccines without interference |
| ATE512670T1 (de) | 2004-04-30 | 2011-07-15 | Novartis Vaccines & Diagnostic | Meningokokken-konjugat-impfung |
| GB0500787D0 (en) | 2005-01-14 | 2005-02-23 | Chiron Srl | Integration of meningococcal conjugate vaccination |
| EP1784214A4 (en) * | 2004-08-30 | 2009-09-23 | Sanofi Pasteur Inc | POLYSACCHARIDE / PROTEIN CONJUGATES MULTIVALENT MENINGOCOCCUS DERIVATIVE AND VACCINE |
| JP2008513541A (ja) * | 2004-09-21 | 2008-05-01 | サノフィ パストゥール インコーポレイテッド | 多価髄膜炎菌誘導体化多糖−タンパク質複合体およびワクチン |
| US8398983B2 (en) | 2005-06-27 | 2013-03-19 | Glaxosmithkline Biologicals, S.A. | Immunogenic composition |
| GB0513071D0 (en) * | 2005-06-27 | 2005-08-03 | Glaxosmithkline Biolog Sa | Immunogenic composition |
| US7955817B2 (en) | 2005-09-02 | 2011-06-07 | Glaxosmithkline Biologicals S.A. | Vaccine protection assay |
| DE602005024320D1 (de) | 2005-09-05 | 2010-12-02 | Glaxosmithkline Biolog Sa | Bakterizidie-serumtest für n. meningitidis spezifische antiseren |
| AU2007227504B2 (en) | 2006-03-17 | 2013-10-31 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Methods for preparing complex multivalent immunogenic conjugates |
| PL2004225T3 (pl) | 2006-03-22 | 2012-09-28 | Novartis Ag | Schematy immunizacji koniugatami meningokokowymi |
| US10828361B2 (en) * | 2006-03-22 | 2020-11-10 | Glaxosmithkline Biologicals Sa | Regimens for immunisation with meningococcal conjugates |
| WO2007116409A2 (en) | 2006-04-11 | 2007-10-18 | Yeda Research And Development Co. Ltd. At The Weizmann Institute Of Science | Improved vaccines comprising multimeric hsp60 peptide carriers |
| US7491517B2 (en) * | 2006-07-19 | 2009-02-17 | Jeeri R Reddy | Method of producing meningococcal meningitis vaccine for Neisseria meningitidis serotypes A,C,Y, and W-135 |
| CN101428144A (zh) * | 2008-12-19 | 2009-05-13 | 长春长生生物科技股份有限公司 | 流脑多糖联合疫苗及制备工艺 |
| CN102858370A (zh) * | 2010-05-03 | 2013-01-02 | Dcb-美国有限责任公司 | 用作疫苗的多糖与去毒大肠杆菌(e.coli)不耐热肠毒素(lt)的偶联 |
| CN103623401A (zh) * | 2012-08-23 | 2014-03-12 | 北京科兴中维生物技术有限公司 | 多价肺炎球菌荚膜多糖-蛋白质共轭组合物及其制备方法 |
| CN102861326A (zh) * | 2012-09-19 | 2013-01-09 | 天津康希诺生物技术有限公司 | 流脑多糖-蛋白质缀合疫苗及制备方法 |
| CN104829711B (zh) * | 2014-04-08 | 2018-04-03 | 北京天成新脉生物技术有限公司 | 脑膜炎球菌荚膜多糖单克隆抗体及其应用 |
| KR102906912B1 (ko) | 2016-09-02 | 2026-01-05 | 사노피 파스퇴르 인크 | 네이세리아 메닌기티디스 백신 |
| CN108743936B (zh) * | 2018-06-14 | 2022-03-15 | 中国科学院过程工程研究所 | 一种细菌多糖结合疫苗及其制备方法与应用 |
| EP4034157A1 (en) * | 2019-09-27 | 2022-08-03 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4356170A (en) | 1981-05-27 | 1982-10-26 | Canadian Patents & Development Ltd. | Immunogenic polysaccharide-protein conjugates |
| US4619828A (en) | 1982-07-06 | 1986-10-28 | Connaught Laboratories, Inc. | Polysaccharide exotoxoid conjugate vaccines |
| HU212924B (en) | 1989-05-25 | 1996-12-30 | Chiron Corp | Adjuvant formulation comprising a submicron oil droplet emulsion |
| US5153312A (en) | 1990-09-28 | 1992-10-06 | American Cyanamid Company | Oligosaccharide conjugate vaccines |
| US5422427A (en) | 1991-09-17 | 1995-06-06 | The United States Of America As Represented By The United States Department Of Health And Human Services | Pneumococcal fimbrial protein A |
| US5445817A (en) | 1992-08-21 | 1995-08-29 | The United States Of America As Represented By The Department Of Health And Human Services | Pertussis toxin used as a carrier protein with non-charged saccharides in conjugate vaccines |
| US5965714A (en) * | 1997-10-02 | 1999-10-12 | Connaught Laboratories, Inc. | Method for the covalent attachment of polysaccharides to protein molecules |
| US6146902A (en) | 1998-12-29 | 2000-11-14 | Aventis Pasteur, Inc. | Purification of polysaccharide-protein conjugate vaccines by ultrafiltration with ammonium sulfate solutions |
| AU2002309706A1 (en) * | 2001-05-11 | 2002-11-25 | Aventis Pasteur, Inc. | Novel meningitis conjugate vaccine |
-
2004
- 2004-05-07 CN CNA2004800193066A patent/CN1852733A/zh not_active Withdrawn
- 2004-05-07 EP EP10183290A patent/EP2386313A1/en not_active Withdrawn
- 2004-05-07 US US10/841,294 patent/US20050002957A1/en not_active Abandoned
- 2004-05-07 CN CN201410415117.6A patent/CN104225587B/zh not_active Expired - Lifetime
- 2004-05-07 BR BRPI0410341A patent/BRPI0410341B8/pt active IP Right Grant
- 2004-05-07 CA CA2524860A patent/CA2524860C/en not_active Expired - Lifetime
- 2004-05-07 WO PCT/US2004/014466 patent/WO2004103400A2/en not_active Ceased
- 2004-05-07 JP JP2006529366A patent/JP2006528936A/ja active Pending
- 2004-05-07 AU AU2004240558A patent/AU2004240558A1/en not_active Abandoned
- 2004-05-07 EP EP04751728.9A patent/EP1624888B1/en not_active Expired - Lifetime
-
2010
- 2010-12-01 JP JP2010268151A patent/JP2011042693A/ja active Pending
- 2010-12-16 AU AU2010257242A patent/AU2010257242A1/en not_active Ceased
-
2014
- 2014-07-04 JP JP2014138526A patent/JP2014193929A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA2524860A1 (en) | 2004-12-02 |
| JP2011042693A (ja) | 2011-03-03 |
| CN104225587B (zh) | 2017-07-21 |
| JP2006528936A (ja) | 2006-12-28 |
| CN1852733A (zh) | 2006-10-25 |
| WO2004103400A2 (en) | 2004-12-02 |
| CA2524860C (en) | 2016-09-13 |
| BRPI0410341B1 (pt) | 2019-07-16 |
| WO2004103400A3 (en) | 2005-03-24 |
| AU2004240558A1 (en) | 2004-12-02 |
| BRPI0410341A (pt) | 2006-05-30 |
| HK1204574A1 (en) | 2015-11-27 |
| CN104225587A (zh) | 2014-12-24 |
| EP2386313A1 (en) | 2011-11-16 |
| AU2010257242A1 (en) | 2011-01-13 |
| JP2014193929A (ja) | 2014-10-09 |
| EP1624888B1 (en) | 2016-10-12 |
| US20050002957A1 (en) | 2005-01-06 |
| EP1624888A2 (en) | 2006-02-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B25E | Requested change of name of applicant rejected |
Owner name: SANOFI PASTEUR INC. (US) |
|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B07E | Notice of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
| B06T | Formal requirements before examination [chapter 6.20 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 16/07/2019, OBSERVADAS AS CONDICOES LEGAIS. (CO) 10 (DEZ) ANOS CONTADOS A PARTIR DE 16/07/2019, OBSERVADAS AS CONDICOES LEGAIS |
|
| B16C | Correction of notification of the grant [chapter 16.3 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 07/05/2004 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF |