BRPI0515125A - conjugados de polissacarìdeo derivatizado-proteìna multivalentes, meningocócicos e vacina - Google Patents

conjugados de polissacarìdeo derivatizado-proteìna multivalentes, meningocócicos e vacina

Info

Publication number
BRPI0515125A
BRPI0515125A BRPI0515125-2A BRPI0515125A BRPI0515125A BR PI0515125 A BRPI0515125 A BR PI0515125A BR PI0515125 A BRPI0515125 A BR PI0515125A BR PI0515125 A BRPI0515125 A BR PI0515125A
Authority
BR
Brazil
Prior art keywords
protein
derivatized
conjugates
vaccine
polysaccharide conjugates
Prior art date
Application number
BRPI0515125-2A
Other languages
English (en)
Inventor
Robert P Ryall
Original Assignee
Sanofi Pasteur Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Pasteur Inc filed Critical Sanofi Pasteur Inc
Publication of BRPI0515125A publication Critical patent/BRPI0515125A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/385—Haptens or antigens, bound to carriers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/116—Polyvalent bacterial antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

CONJUGADOS DE POLISSACARìDEO DERIVATIZADO-PROTEìNA MULTIVALENTES, MENINGOCóCICOS E VACINA. A presente invenção refere-se a conjugados de polissacarídeo derivatizado-proteína, uma composição compreendendo um ou mais de tais conjugados de polissacarídeo derivatizado e métodos para imunização de pacientes humanos com os mesmos. Os conjugados de polissacarídeo derivatizado-proteína são polissacarídeos capsulares purificados dos sorogrupos de Neisseria meningitidis A, C, W-135 e Y, derivatizados, ativados químicamente e anexados seletivamente a uma proteína veículo por meio de uma ligação química covalente, formando conjugados de polissacarídeo-proteína capazes de promover a imunidade de longa duração contra várias cepas de N. meningitidis.
BRPI0515125-2A 2004-08-30 2005-08-29 conjugados de polissacarìdeo derivatizado-proteìna multivalentes, meningocócicos e vacina BRPI0515125A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60557904P 2004-08-30 2004-08-30
PCT/US2005/031034 WO2006026689A2 (en) 2004-08-30 2005-08-29 Multivalent meningococcal derivatized polysaccharide-protein conjugates and vaccine

Publications (1)

Publication Number Publication Date
BRPI0515125A true BRPI0515125A (pt) 2008-07-08

Family

ID=36000720

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0515125-2A BRPI0515125A (pt) 2004-08-30 2005-08-29 conjugados de polissacarìdeo derivatizado-proteìna multivalentes, meningocócicos e vacina

Country Status (11)

Country Link
US (1) US20060088554A1 (pt)
EP (2) EP1784214A4 (pt)
JP (2) JP2008517876A (pt)
KR (1) KR20070101207A (pt)
CN (2) CN101048177A (pt)
AU (1) AU2005279821A1 (pt)
BR (1) BRPI0515125A (pt)
CA (1) CA2577920A1 (pt)
IL (1) IL181551A0 (pt)
WO (1) WO2006026689A2 (pt)
ZA (1) ZA200701675B (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2005286798A1 (en) * 2004-09-21 2006-03-30 Sanofi Pasteur, Inc. Multivalent meningococcal derivatized polysaccharide-protein conjugates and vaccine
ES2670231T3 (es) 2006-03-22 2018-05-29 Glaxosmithkline Biologicals S.A. Regímenes para inmunización con conjugados meningocócicos
US10828361B2 (en) 2006-03-22 2020-11-10 Glaxosmithkline Biologicals Sa Regimens for immunisation with meningococcal conjugates
US7491517B2 (en) * 2006-07-19 2009-02-17 Jeeri R Reddy Method of producing meningococcal meningitis vaccine for Neisseria meningitidis serotypes A,C,Y, and W-135
WO2013046226A2 (en) * 2011-08-04 2013-04-04 Serum Institute Of India Ltd. A novel quantification method for vaccines
CN103007268A (zh) * 2012-12-26 2013-04-03 天津康希诺生物技术有限公司 一种低剂量多价结合疫苗组合物及用途
CN103893751B (zh) * 2014-03-26 2016-04-20 天津康希诺生物技术有限公司 一种肺炎球菌多糖蛋白缀合疫苗及其制备方法
SG11201901394XA (en) 2016-09-02 2019-03-28 Sanofi Pasteur Inc Neisseria meningitidis vaccine

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4356170A (en) 1981-05-27 1982-10-26 Canadian Patents & Development Ltd. Immunogenic polysaccharide-protein conjugates
US4619828A (en) 1982-07-06 1986-10-28 Connaught Laboratories, Inc. Polysaccharide exotoxoid conjugate vaccines
JPH0832638B2 (ja) 1989-05-25 1996-03-29 カイロン コーポレイション サブミクロン油滴乳剤を含んで成るアジュバント製剤
US5153312A (en) 1990-09-28 1992-10-06 American Cyanamid Company Oligosaccharide conjugate vaccines
US5422427A (en) 1991-09-17 1995-06-06 The United States Of America As Represented By The United States Department Of Health And Human Services Pneumococcal fimbrial protein A
US5445817A (en) 1992-08-21 1995-08-29 The United States Of America As Represented By The Department Of Health And Human Services Pertussis toxin used as a carrier protein with non-charged saccharides in conjugate vaccines
US5965714A (en) * 1997-10-02 1999-10-12 Connaught Laboratories, Inc. Method for the covalent attachment of polysaccharides to protein molecules
US6146902A (en) 1998-12-29 2000-11-14 Aventis Pasteur, Inc. Purification of polysaccharide-protein conjugate vaccines by ultrafiltration with ammonium sulfate solutions
PT2332581E (pt) * 2001-01-23 2015-10-16 Sanofi Pasteur Inc Vacina meningocócica tri- ou tetravalente de conjugados de polissacárido e crm-197
AU2002309706A1 (en) * 2001-05-11 2002-11-25 Aventis Pasteur, Inc. Novel meningitis conjugate vaccine
GB0115176D0 (en) * 2001-06-20 2001-08-15 Chiron Spa Capular polysaccharide solubilisation and combination vaccines
DE60325565D1 (de) * 2002-03-26 2009-02-12 Novartis Vaccines & Diagnostic Modifizierte saccharide mit verbesserter stabilität in wasser
CN1819843A (zh) * 2003-05-07 2006-08-16 安万特巴斯德公司 增强脑膜炎球菌疫苗接种免疫原性的方法
AU2004240558A1 (en) * 2003-05-07 2004-12-02 Aventis Pasteur, Inc. Multivalent meningococcal derivatized polysaccharide-protein conjugates and corresponding vaccines
AU2005286798A1 (en) * 2004-09-21 2006-03-30 Sanofi Pasteur, Inc. Multivalent meningococcal derivatized polysaccharide-protein conjugates and vaccine

Also Published As

Publication number Publication date
US20060088554A1 (en) 2006-04-27
CN101048177A (zh) 2007-10-03
WO2006026689A2 (en) 2006-03-09
EP1784214A2 (en) 2007-05-16
IL181551A0 (en) 2007-07-04
CN101934077A (zh) 2011-01-05
WO2006026689A3 (en) 2006-07-27
JP2012140456A (ja) 2012-07-26
KR20070101207A (ko) 2007-10-16
CA2577920A1 (en) 2006-03-09
AU2005279821A1 (en) 2006-03-09
ZA200701675B (en) 2008-11-26
EP2351582A1 (en) 2011-08-03
JP2008517876A (ja) 2008-05-29
EP1784214A4 (en) 2009-09-23

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 9A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2269 DE 01/07/2014.