BR9916724A - Produção de monelina recombinante utilizando sistema de expressão em leveduras metilotróficas - Google Patents

Produção de monelina recombinante utilizando sistema de expressão em leveduras metilotróficas

Info

Publication number
BR9916724A
BR9916724A BR9916724-7A BR9916724A BR9916724A BR 9916724 A BR9916724 A BR 9916724A BR 9916724 A BR9916724 A BR 9916724A BR 9916724 A BR9916724 A BR 9916724A
Authority
BR
Brazil
Prior art keywords
monelin
recombinant
protein
production
nucleic acid
Prior art date
Application number
BR9916724-7A
Other languages
English (en)
Portuguese (pt)
Inventor
Lingxun Duan
Original Assignee
Genway Biotech Inc
Lingxun Duan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genway Biotech Inc, Lingxun Duan filed Critical Genway Biotech Inc
Publication of BR9916724A publication Critical patent/BR9916724A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • C07K14/43—Sweetening agents, e.g. thaumatin, monellin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
BR9916724-7A 1998-12-31 1999-12-09 Produção de monelina recombinante utilizando sistema de expressão em leveduras metilotróficas BR9916724A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11452998P 1998-12-31 1998-12-31
PCT/US1999/029213 WO2000040603A2 (en) 1998-12-31 1999-12-09 Production of recombinant monellin using methylotrophic yeast expression system

Publications (1)

Publication Number Publication Date
BR9916724A true BR9916724A (pt) 2001-09-11

Family

ID=22355787

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9916724-7A BR9916724A (pt) 1998-12-31 1999-12-09 Produção de monelina recombinante utilizando sistema de expressão em leveduras metilotróficas

Country Status (9)

Country Link
EP (1) EP1141304A2 (ko)
JP (1) JP2002534074A (ko)
KR (1) KR20020008819A (ko)
CN (1) CN1332802A (ko)
AU (1) AU3116100A (ko)
BR (1) BR9916724A (ko)
CA (1) CA2364005A1 (ko)
IL (1) IL143771A0 (ko)
WO (1) WO2000040603A2 (ko)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117088958A (zh) * 2022-05-20 2023-11-21 南京百斯杰生物工程有限公司 具有高甜度的甜味蛋白莫内林(Monellin)突变体及其制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3998798A (en) * 1972-12-22 1976-12-21 The Trustees Of The University Of Pennsylvania Monellin, a sweet polypeptide derived from fruit of dioscoreophyllum cumminsii
ATE108185T1 (de) * 1987-06-19 1994-07-15 Univ California Neue klasse von niedrigkalorischen proteinsüssstoffen.
US6001410A (en) * 1996-07-25 1999-12-14 International Flavors & Fragrances Inc. Fruit liqueur beverage containing recombinant monellin to enhance the alcoholic impact

Also Published As

Publication number Publication date
EP1141304A2 (en) 2001-10-10
KR20020008819A (ko) 2002-01-31
CA2364005A1 (en) 2000-07-13
AU3116100A (en) 2000-07-24
CN1332802A (zh) 2002-01-23
JP2002534074A (ja) 2002-10-15
WO2000040603A3 (en) 2000-09-21
WO2000040603A2 (en) 2000-07-13
IL143771A0 (en) 2002-04-21

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Legal Events

Date Code Title Description
FA10 Dismissal: dismissal - article 33 of industrial property law
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]